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HUMA vs ANGO vs NVCR vs ATRC
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Instruments & Supplies
Medical - Instruments & Supplies
Medical - Instruments & Supplies
HUMA vs ANGO vs NVCR vs ATRC — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Medical - Instruments & Supplies | Medical - Instruments & Supplies | Medical - Instruments & Supplies |
| Market Cap | $140M | $469M | $1.92B | $1.41B |
| Revenue (TTM) | $9M | $307M | $674M | $552M |
| Net Income (TTM) | $-37M | $-28M | $-173M | $-5M |
| Gross Margin | 9.9% | 53.7% | 75.2% | 75.5% |
| Operating Margin | -12.0% | -9.4% | -27.2% | -0.4% |
| Forward P/E | — | — | — | 370.7x |
| Total Debt | $17M | $0.00 | $290M | $88M |
| Cash & Equiv. | $45M | $56M | $103M | $167M |
HUMA vs ANGO vs NVCR vs ATRC — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Dec 20 | May 26 | Return |
|---|---|---|---|
| Humacyte, Inc. (HUMA) | 100 | 10.6 | -89.4% |
| AngioDynamics, Inc. (ANGO) | 100 | 73.5 | -26.5% |
| NovoCure Limited (NVCR) | 100 | 9.7 | -90.3% |
| AtriCure, Inc. (ATRC) | 100 | 49.9 | -50.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: HUMA vs ANGO vs NVCR vs ATRC
Each card shows where this stock fits in a portfolio — not just who wins on paper.
HUMA is the #2 pick in this set and the best alternative if growth is your priority.
- 79.5% revenue growth vs ANGO's -3.8%
ANGO is the clearest fit if your priority is momentum.
- +28.5% vs HUMA's -11.5%
NVCR lags the leaders in this set but could rank higher in a more targeted comparison.
ATRC carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.03
- Rev growth 14.9%, EPS growth 74.7%, 3Y rev CAGR 17.4%
- 95.1% 10Y total return vs ANGO's -9.2%
- Lower volatility, beta 1.03, Low D/E 17.9%, current ratio 3.96x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 79.5% revenue growth vs ANGO's -3.8% | |
| Quality / Margins | -0.8% margin vs HUMA's -420.2% | |
| Stability / Safety | Beta 1.03 vs HUMA's 3.27 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +28.5% vs HUMA's -11.5% | |
| Efficiency (ROA) | -0.7% ROA vs HUMA's -40.4% |
HUMA vs ANGO vs NVCR vs ATRC — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
HUMA vs ANGO vs NVCR vs ATRC — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ATRC leads in 2 of 6 categories
ANGO leads 2 • HUMA leads 0 • NVCR leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ATRC leads this category, winning 6 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVCR is the larger business by revenue, generating $674M annually — 76.6x HUMA's $9M. Profitability is closely matched — net margins range from -0.8% (ATRC) to -4.2% (HUMA). On growth, ATRC holds the edge at +14.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $9M | $307M | $674M | $552M |
| EBITDAEarnings before interest/tax | -$98M | -$5M | -$165M | $13M |
| Net IncomeAfter-tax profit | -$37M | -$28M | -$173M | -$5M |
| Free Cash FlowCash after capex | -$106M | -$9M | -$48M | $54M |
| Gross MarginGross profit ÷ Revenue | +9.9% | +53.7% | +75.2% | +75.5% |
| Operating MarginEBIT ÷ Revenue | -12.0% | -9.4% | -27.2% | -0.4% |
| Net MarginNet income ÷ Revenue | -4.2% | -9.0% | -25.7% | -0.8% |
| FCF MarginFCF ÷ Revenue | -12.1% | -3.0% | -7.1% | +9.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +9.0% | +12.3% | +14.3% |
| EPS Growth (YoY)Latest quarter vs prior year | +66.7% | +42.3% | -100.0% | +101.6% |
Valuation Metrics
ANGO leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $140M | $469M | $1.9B | $1.4B |
| Enterprise ValueMkt cap + debt − cash | $112M | $413M | $2.1B | $1.3B |
| Trailing P/EPrice ÷ TTM EPS | -0.86x | -13.58x | -13.80x | -115.83x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 370.67x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | 77.75x |
| Price / SalesMarket cap ÷ Revenue | — | 1.60x | 2.92x | 2.63x |
| Price / BookPrice ÷ Book value/share | — | 2.52x | 5.51x | 2.70x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 29.15x |
Profitability & Efficiency
ATRC leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
ATRC delivers a -1.0% return on equity — every $100 of shareholder capital generates $-1 in annual profit, vs $-51 for NVCR. ATRC carries lower financial leverage with a 0.18x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), ANGO scores 5/9 vs HUMA's 2/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | — | -15.7% | -50.8% | -1.0% |
| ROA (TTM)Return on assets | -40.4% | -10.3% | -16.5% | -0.7% |
| ROICReturn on invested capital | — | -22.9% | -16.4% | -0.6% |
| ROCEReturn on capital employed | -100.5% | -18.6% | -28.9% | -0.6% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 5 | 5 | 5 |
| Debt / EquityFinancial leverage | — | — | 0.85x | 0.18x |
| Net DebtTotal debt minus cash | -$28M | -$56M | $187M | -$79M |
| Cash & Equiv.Liquid assets | $45M | $56M | $103M | $167M |
| Total DebtShort + long-term debt | $17M | $0 | $290M | $88M |
| Interest CoverageEBIT ÷ Interest expense | -2.47x | -258.19x | -96.80x | 0.47x |
Total Returns (Dividends Reinvested)
ANGO leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ANGO five years ago would be worth $4,674 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, ANGO leads with a +28.5% total return vs HUMA's -11.5%. The 3-year compound annual growth rate (CAGR) favors ANGO at 7.9% vs HUMA's -39.9% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +10.8% | -11.1% | +28.3% | -29.2% |
| 1-Year ReturnPast 12 months | -11.5% | +28.5% | +1.1% | -8.3% |
| 3-Year ReturnCumulative with dividends | -78.3% | +25.8% | -75.7% | -41.8% |
| 5-Year ReturnCumulative with dividends | -89.2% | -53.3% | -91.3% | -64.2% |
| 10-Year ReturnCumulative with dividends | -88.8% | -9.2% | +30.3% | +95.1% |
| CAGR (3Y)Annualised 3-year return | -39.9% | +7.9% | -37.6% | -16.5% |
Risk & Volatility
Evenly matched — NVCR and ATRC each lead in 1 of 2 comparable metrics.
Risk & Volatility
ATRC is the less volatile stock with a 1.03 beta — it tends to amplify market swings less than HUMA's 3.27 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NVCR currently trades 83.9% from its 52-week high vs HUMA's 36.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 3.27x | 1.32x | 2.20x | 1.03x |
| 52-Week HighHighest price in past year | $2.93 | $13.99 | $20.06 | $43.18 |
| 52-Week LowLowest price in past year | $0.55 | $8.36 | $9.82 | $26.62 |
| % of 52W HighCurrent price vs 52-week peak | +36.9% | +80.6% | +83.9% | +64.4% |
| RSI (14)Momentum oscillator 0–100 | 65.9 | 54.0 | 69.8 | 45.0 |
| Avg Volume (50D)Average daily shares traded | 6.7M | 395K | 1.5M | 669K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: HUMA as "Buy", ANGO as "Hold", NVCR as "Buy", ATRC as "Buy". Consensus price targets imply 177.8% upside for HUMA (target: $3) vs 46.4% for ANGO (target: $17).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | $3.00 | $16.50 | $33.50 | $50.67 |
| # AnalystsCovering analysts | 11 | 11 | 15 | 19 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.4% | 0.0% | +0.8% |
ATRC leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ANGO leads in 2 (Valuation Metrics, Total Returns). 1 tied.
HUMA vs ANGO vs NVCR vs ATRC: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is HUMA or ANGO or NVCR or ATRC a better buy right now?
For growth investors, AtriCure, Inc.
(ATRC) is the stronger pick with 14. 9% revenue growth year-over-year, versus -3. 8% for AngioDynamics, Inc. (ANGO). Analysts rate Humacyte, Inc. (HUMA) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — HUMA or ANGO or NVCR or ATRC?
Over the past 5 years, AngioDynamics, Inc.
(ANGO) delivered a total return of -53. 3%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: ATRC returned +95. 1% versus HUMA's -88. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — HUMA or ANGO or NVCR or ATRC?
By beta (market sensitivity over 5 years), AtriCure, Inc.
(ATRC) is the lower-risk stock at 1. 03β versus Humacyte, Inc. 's 3. 27β — meaning HUMA is approximately 219% more volatile than ATRC relative to the S&P 500. On balance sheet safety, AtriCure, Inc. (ATRC) carries a lower debt/equity ratio of 18% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.
04Which is growing faster — HUMA or ANGO or NVCR or ATRC?
By revenue growth (latest reported year), AtriCure, Inc.
(ATRC) is pulling ahead at 14. 9% versus -3. 8% for AngioDynamics, Inc. (ANGO). On earnings-per-share growth, the picture is similar: AngioDynamics, Inc. grew EPS 81. 9% year-over-year, compared to -17. 8% for Humacyte, Inc.. Over a 3-year CAGR, ATRC leads at 17. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — HUMA or ANGO or NVCR or ATRC?
AtriCure, Inc.
(ATRC) is the more profitable company, earning -2. 1% net margin versus -420. 2% for Humacyte, Inc. — meaning it keeps -2. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ATRC leads at -0. 6% versus -1197. 7% for HUMA. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is HUMA or ANGO or NVCR or ATRC more undervalued right now?
Analyst consensus price targets imply the most upside for HUMA: 177.
8% to $3. 00.
07Which pays a better dividend — HUMA or ANGO or NVCR or ATRC?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is HUMA or ANGO or NVCR or ATRC better for a retirement portfolio?
For long-horizon retirement investors, AtriCure, Inc.
(ATRC) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 03)). Humacyte, Inc. (HUMA) carries a higher beta of 3. 27 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ATRC: +95. 1%, HUMA: -88. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between HUMA and ANGO and NVCR and ATRC?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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