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Stock Comparison

IART vs JNJ vs HOLX vs SYK vs BDX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
IART
Integra LifeSciences Holdings Corporation

Medical - Devices

HealthcareNASDAQ • US
Market Cap$1.06B
5Y Perf.-74.0%
JNJ
Johnson & Johnson

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$536.23B
5Y Perf.+49.6%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+42.6%
SYK
Stryker Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$112.69B
5Y Perf.+50.3%
BDX
Becton, Dickinson and Company

Medical - Instruments & Supplies

HealthcareNYSE • US
Market Cap$55.53B
5Y Perf.+3.0%

IART vs JNJ vs HOLX vs SYK vs BDX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
IART logoIART
JNJ logoJNJ
HOLX logoHOLX
SYK logoSYK
BDX logoBDX
IndustryMedical - DevicesDrug Manufacturers - GeneralMedical - Instruments & SuppliesMedical - DevicesMedical - Instruments & Supplies
Market Cap$1.06B$536.23B$16.97B$112.69B$55.53B
Revenue (TTM)$1.64B$92.15B$4.13B$25.12B$21.36B
Net Income (TTM)$-496M$25.12B$544M$3.25B$1.14B
Gross Margin39.6%68.1%52.8%63.5%46.5%
Operating Margin5.8%26.1%17.5%22.4%10.6%
Forward P/E5.8x19.2x17.2x19.6x12.3x
Total Debt$2.03B$36.63B$2.63B$14.86B$19.18B
Cash & Equiv.$235M$24.11B$1.96B$4.01B$851M

IART vs JNJ vs HOLX vs SYK vs BDXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

IART
JNJ
HOLX
SYK
BDX
StockMay 20May 26Return
Integra LifeScience… (IART)10026.0-74.0%
Johnson & Johnson (JNJ)100149.6+49.6%
Hologic, Inc. (HOLX)100142.6+42.6%
Stryker Corporation (SYK)100150.3+50.3%
Becton, Dickinson a… (BDX)100103.0+3.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: IART vs JNJ vs HOLX vs SYK vs BDX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: JNJ leads in 3 of 7 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Becton, Dickinson and Company is the stronger pick specifically for dividend income and shareholder returns and recent price momentum and sentiment. IART and SYK also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
IART
Integra LifeSciences Holdings Corporation
The Value Play

IART ranks third and is worth considering specifically for value.

  • Lower P/E (5.8x vs 19.6x)
Best for: value
JNJ
Johnson & Johnson
The Income Pick

JNJ carries the broadest edge in this set and is the clearest fit for income & stability and defensive.

  • Dividend streak 36 yrs, beta 0.06, yield 2.2%
  • Beta 0.06, yield 2.2%, current ratio 1.11x
  • 27.3% margin vs IART's -30.1%
  • Beta 0.06 vs IART's 2.34, lower leverage
Best for: income & stability and defensive
HOLX
Hologic, Inc.
The Defensive Pick

HOLX is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.41, Low D/E 52.0%, current ratio 3.75x
Best for: sleep-well-at-night
SYK
Stryker Corporation
The Growth Play

SYK is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth 11.2%, EPS growth 8.2%, 3Y rev CAGR 10.8%
  • 187.1% 10Y total return vs JNJ's 132.3%
  • 11.2% revenue growth vs IART's 1.5%
Best for: growth exposure and long-term compounding
BDX
Becton, Dickinson and Company
The Value Pick

BDX is the #2 pick in this set and the best alternative if valuation efficiency is your priority.

  • PEG 0.74 vs JNJ's 34.17
  • 2.7% yield, 1-year raise streak, vs JNJ's 2.2%, (2 stocks pay no dividend)
  • +51.8% vs SYK's -22.5%
Best for: valuation efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthSYK logoSYK11.2% revenue growth vs IART's 1.5%
ValueIART logoIARTLower P/E (5.8x vs 19.6x)
Quality / MarginsJNJ logoJNJ27.3% margin vs IART's -30.1%
Stability / SafetyJNJ logoJNJBeta 0.06 vs IART's 2.34, lower leverage
DividendsBDX logoBDX2.7% yield, 1-year raise streak, vs JNJ's 2.2%, (2 stocks pay no dividend)
Momentum (1Y)BDX logoBDX+51.8% vs SYK's -22.5%
Efficiency (ROA)JNJ logoJNJ13.0% ROA vs IART's -13.7%, ROIC 20.7% vs 1.7%

IART vs JNJ vs HOLX vs SYK vs BDX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

IARTIntegra LifeSciences Holdings Corporation
FY 2025
Codman Specialty Surgical
73.4%$1.2B
Tissue Technologies
26.6%$435M
JNJJohnson & Johnson
FY 2024
Innovative Medicine
64.1%$57.0B
MedTech
35.9%$31.9B
HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
SYKStryker Corporation
FY 2025
MedSurg
62.3%$15.6B
Orthopaedics
37.7%$9.5B
BDXBecton, Dickinson and Company
FY 2025
Medical
52.5%$11.5B
Interventional
23.9%$5.2B
Life Sciences
23.7%$5.2B

IART vs JNJ vs HOLX vs SYK vs BDX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLJNJLAGGINGBDX

Income & Cash Flow (Last 12 Months)

JNJ leads this category, winning 4 of 6 comparable metrics.

JNJ is the larger business by revenue, generating $92.1B annually — 56.0x IART's $1.6B. JNJ is the more profitable business, keeping 27.3% of every revenue dollar as net income compared to IART's -30.1%. On growth, SYK holds the edge at +11.4% YoY revenue growth, suggesting stronger near-term business momentum.

MetricIART logoIARTIntegra LifeScien…JNJ logoJNJJohnson & JohnsonHOLX logoHOLXHologic, Inc.SYK logoSYKStryker Corporati…BDX logoBDXBecton, Dickinson…
RevenueTrailing 12 months$1.6B$92.1B$4.1B$25.1B$21.4B
EBITDAEarnings before interest/tax$209M$31.4B$974M$6.3B$4.2B
Net IncomeAfter-tax profit-$496M$25.1B$544M$3.2B$1.1B
Free Cash FlowCash after capex-$10M$19.1B$1000M$4.3B$3.1B
Gross MarginGross profit ÷ Revenue+39.6%+68.1%+52.8%+63.5%+46.5%
Operating MarginEBIT ÷ Revenue+5.8%+26.1%+17.5%+22.4%+10.6%
Net MarginNet income ÷ Revenue-30.1%+27.3%+13.2%+12.9%+5.3%
FCF MarginFCF ÷ Revenue-0.6%+20.7%+24.2%+17.1%+14.7%
Rev. Growth (YoY)Latest quarter vs prior year+2.4%+6.8%+2.5%+11.4%-10.6%
EPS Growth (YoY)Latest quarter vs prior year+81.8%+91.0%-9.2%+56.0%-2.0%
JNJ leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

IART leads this category, winning 5 of 7 comparable metrics.

At 26.3x trailing earnings, BDX trades at a 32% valuation discount to JNJ's 38.4x P/E. Adjusting for growth (PEG ratio), BDX offers better value at 1.59x vs JNJ's 34.17x — a lower PEG means you pay less per unit of expected earnings growth.

MetricIART logoIARTIntegra LifeScien…JNJ logoJNJJohnson & JohnsonHOLX logoHOLXHologic, Inc.SYK logoSYKStryker Corporati…BDX logoBDXBecton, Dickinson…
Market CapShares × price$1.1B$536.2B$17.0B$112.7B$55.5B
Enterprise ValueMkt cap + debt − cash$2.9B$548.8B$17.6B$123.5B$73.9B
Trailing P/EPrice ÷ TTM EPS-2.01x38.43x30.53x35.03x26.29x
Forward P/EPrice ÷ next-FY EPS est.5.77x19.20x17.21x19.62x12.27x
PEG RatioP/E ÷ EPS growth rate34.17x2.36x1.59x
EV / EBITDAEnterprise value multiple13.01x18.61x17.39x20.31x14.65x
Price / SalesMarket cap ÷ Revenue0.65x6.04x4.14x4.49x2.54x
Price / BookPrice ÷ Book value/share1.00x7.56x3.43x5.02x1.73x
Price / FCFMarket cap ÷ FCF27.02x18.44x26.31x20.80x
IART leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

JNJ leads this category, winning 6 of 9 comparable metrics.

JNJ delivers a 31.7% return on equity — every $100 of shareholder capital generates $32 in annual profit, vs $-48 for IART. JNJ carries lower financial leverage with a 0.51x debt-to-equity ratio, signaling a more conservative balance sheet compared to IART's 1.95x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs JNJ's 5/9, reflecting strong financial health.

MetricIART logoIARTIntegra LifeScien…JNJ logoJNJJohnson & JohnsonHOLX logoHOLXHologic, Inc.SYK logoSYKStryker Corporati…BDX logoBDXBecton, Dickinson…
ROE (TTM)Return on equity-47.6%+31.7%+11.0%+15.0%+4.5%
ROA (TTM)Return on assets-13.7%+13.0%+6.1%+6.9%+2.1%
ROICReturn on invested capital+1.7%+20.7%+9.4%+11.4%+4.3%
ROCEReturn on capital employed+2.2%+17.6%+8.8%+13.0%+5.4%
Piotroski ScoreFundamental quality 0–955767
Debt / EquityFinancial leverage1.95x0.51x0.52x0.66x0.76x
Net DebtTotal debt minus cash$1.8B$12.5B$667M$10.8B$18.3B
Cash & Equiv.Liquid assets$235M$24.1B$2.0B$4.0B$851M
Total DebtShort + long-term debt$2.0B$36.6B$2.6B$14.9B$19.2B
Interest CoverageEBIT ÷ Interest expense-10.36x48.23x8.00x6.72x4.09x
JNJ leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

JNJ leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in JNJ five years ago would be worth $14,611 today (with dividends reinvested), compared to $1,827 for IART. Over the past 12 months, BDX leads with a +51.8% total return vs SYK's -22.5%. The 3-year compound annual growth rate (CAGR) favors JNJ at 13.5% vs IART's -35.4% — a key indicator of consistent wealth creation.

MetricIART logoIARTIntegra LifeScien…JNJ logoJNJJohnson & JohnsonHOLX logoHOLXHologic, Inc.SYK logoSYKStryker Corporati…BDX logoBDXBecton, Dickinson…
YTD ReturnYear-to-date+12.9%+7.9%+1.9%-15.2%+0.7%
1-Year ReturnPast 12 months+6.5%+44.8%+37.1%-22.5%+51.8%
3-Year ReturnCumulative with dividends-73.1%+46.3%-8.5%+5.5%+5.0%
5-Year ReturnCumulative with dividends-81.7%+46.1%+15.8%+21.5%+16.9%
10-Year ReturnCumulative with dividends-63.0%+132.3%+124.3%+187.1%+80.2%
CAGR (3Y)Annualised 3-year return-35.4%+13.5%-2.9%+1.8%+1.6%
JNJ leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — JNJ and HOLX each lead in 1 of 2 comparable metrics.

JNJ is the less volatile stock with a 0.06 beta — it tends to amplify market swings less than IART's 2.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs SYK's 72.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricIART logoIARTIntegra LifeScien…JNJ logoJNJJohnson & JohnsonHOLX logoHOLXHologic, Inc.SYK logoSYKStryker Corporati…BDX logoBDXBecton, Dickinson…
Beta (5Y)Sensitivity to S&P 5002.34x0.06x0.41x0.55x0.66x
52-Week HighHighest price in past year$16.49$251.71$76.04$404.87$205.52
52-Week LowLowest price in past year$8.70$146.12$52.81$289.91$100.31
% of 52W HighCurrent price vs 52-week peak+82.2%+88.4%+100.0%+72.7%+74.6%
RSI (14)Momentum oscillator 0–10075.937.169.124.332.2
Avg Volume (50D)Average daily shares traded858K7.0M10.0M2.1M2.5M
Evenly matched — JNJ and HOLX each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — JNJ and BDX each lead in 1 of 2 comparable metrics.

Analyst consensus: IART as "Buy", JNJ as "Buy", HOLX as "Hold", SYK as "Buy", BDX as "Buy". Consensus price targets imply 37.2% upside for SYK (target: $404) vs -11.5% for IART (target: $12). For income investors, BDX offers the higher dividend yield at 2.72% vs SYK's 1.14%.

MetricIART logoIARTIntegra LifeScien…JNJ logoJNJJohnson & JohnsonHOLX logoHOLXHologic, Inc.SYK logoSYKStryker Corporati…BDX logoBDXBecton, Dickinson…
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuyBuy
Price TargetConsensus 12-month target$12.00$249.27$79.00$403.69$172.85
# AnalystsCovering analysts2640425033
Dividend YieldAnnual dividend ÷ price+2.2%+1.1%+2.7%
Dividend StreakConsecutive years of raises036341
Dividend / ShareAnnual DPS$4.87$3.36$4.17
Buyback YieldShare repurchases ÷ mkt cap+0.0%+0.5%+4.4%0.0%+1.8%
Evenly matched — JNJ and BDX each lead in 1 of 2 comparable metrics.
Key Takeaway

JNJ leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IART leads in 1 (Valuation Metrics). 2 tied.

Best OverallJohnson & Johnson (JNJ)Leads 3 of 6 categories
Loading custom metrics...

IART vs JNJ vs HOLX vs SYK vs BDX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is IART or JNJ or HOLX or SYK or BDX a better buy right now?

For growth investors, Stryker Corporation (SYK) is the stronger pick with 11.

2% revenue growth year-over-year, versus 1. 5% for Integra LifeSciences Holdings Corporation (IART). Becton, Dickinson and Company (BDX) offers the better valuation at 26. 3x trailing P/E (12. 3x forward), making it the more compelling value choice. Analysts rate Integra LifeSciences Holdings Corporation (IART) a "Buy" — based on 26 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — IART or JNJ or HOLX or SYK or BDX?

On trailing P/E, Becton, Dickinson and Company (BDX) is the cheapest at 26.

3x versus Johnson & Johnson at 38. 4x. On forward P/E, Integra LifeSciences Holdings Corporation is actually cheaper at 5. 8x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Becton, Dickinson and Company wins at 0. 74x versus Johnson & Johnson's 34. 17x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — IART or JNJ or HOLX or SYK or BDX?

Over the past 5 years, Johnson & Johnson (JNJ) delivered a total return of +46.

1%, compared to -81. 7% for Integra LifeSciences Holdings Corporation (IART). Over 10 years, the gap is even starker: SYK returned +187. 1% versus IART's -63. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — IART or JNJ or HOLX or SYK or BDX?

By beta (market sensitivity over 5 years), Johnson & Johnson (JNJ) is the lower-risk stock at 0.

06β versus Integra LifeSciences Holdings Corporation's 2. 34β — meaning IART is approximately 4001% more volatile than JNJ relative to the S&P 500. On balance sheet safety, Johnson & Johnson (JNJ) carries a lower debt/equity ratio of 51% versus 195% for Integra LifeSciences Holdings Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — IART or JNJ or HOLX or SYK or BDX?

By revenue growth (latest reported year), Stryker Corporation (SYK) is pulling ahead at 11.

2% versus 1. 5% for Integra LifeSciences Holdings Corporation (IART). On earnings-per-share growth, the picture is similar: Stryker Corporation grew EPS 8. 2% year-over-year, compared to -73. 6% for Integra LifeSciences Holdings Corporation. Over a 3-year CAGR, SYK leads at 10. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — IART or JNJ or HOLX or SYK or BDX?

Johnson & Johnson (JNJ) is the more profitable company, earning 15.

8% net margin versus -31. 6% for Integra LifeSciences Holdings Corporation — meaning it keeps 15. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JNJ leads at 24. 9% versus 4. 2% for IART. At the gross margin level — before operating expenses — JNJ leads at 69. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is IART or JNJ or HOLX or SYK or BDX more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Becton, Dickinson and Company (BDX) is the more undervalued stock at a PEG of 0. 74x versus Johnson & Johnson's 34. 17x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Integra LifeSciences Holdings Corporation (IART) trades at 5. 8x forward P/E versus 19. 6x for Stryker Corporation — 13. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for SYK: 37. 2% to $403. 69.

08

Which pays a better dividend — IART or JNJ or HOLX or SYK or BDX?

In this comparison, BDX (2.

7% yield), JNJ (2. 2% yield), SYK (1. 1% yield) pay a dividend. IART, HOLX do not pay a meaningful dividend and should not be held primarily for income.

09

Is IART or JNJ or HOLX or SYK or BDX better for a retirement portfolio?

For long-horizon retirement investors, Johnson & Johnson (JNJ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

06), 2. 2% yield, +132. 3% 10Y return). Integra LifeSciences Holdings Corporation (IART) carries a higher beta of 2. 34 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (JNJ: +132. 3%, IART: -63. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between IART and JNJ and HOLX and SYK and BDX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

JNJ, SYK, BDX pay a dividend while IART, HOLX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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(IART: 2.4% · JNJ: 6.8%)

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