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Stock Comparison

IART vs NTRA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
IART
Integra LifeSciences Holdings Corporation

Medical - Devices

HealthcareNASDAQ • US
Market Cap$1.06B
5Y Perf.-74.0%
NTRA
Natera, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$31.16B
5Y Perf.+401.3%

IART vs NTRA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
IART logoIART
NTRA logoNTRA
IndustryMedical - DevicesMedical - Diagnostics & Research
Market Cap$1.06B$31.16B
Revenue (TTM)$1.64B$2.31B
Net Income (TTM)$-496M$-208M
Gross Margin39.6%64.8%
Operating Margin5.8%-13.4%
Forward P/E5.8x
Total Debt$2.03B$214M
Cash & Equiv.$235M$1.08B

IART vs NTRALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

IART
NTRA
StockMay 20May 26Return
Integra LifeScience… (IART)10026.0-74.0%
Natera, Inc. (NTRA)100501.3+401.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: IART vs NTRA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: NTRA leads in 5 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. As sector peers, any of these can serve as alternatives in the same allocation.
IART
Integra LifeSciences Holdings Corporation
The Value Angle

In this particular matchup, IART is outpaced on most metrics by others in the set.

Best for: healthcare exposure
NTRA
Natera, Inc.
The Income Pick

NTRA carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 1.26
  • Rev growth 35.9%, EPS growth 0.7%, 3Y rev CAGR 41.1%
  • 20.9% 10Y total return vs IART's -63.0%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthNTRA logoNTRA35.9% revenue growth vs IART's 1.5%
Quality / MarginsNTRA logoNTRA-9.0% margin vs IART's -30.1%
Stability / SafetyNTRA logoNTRABeta 1.26 vs IART's 2.34, lower leverage
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)NTRA logoNTRA+37.3% vs IART's +6.5%
Efficiency (ROA)NTRA logoNTRA-10.6% ROA vs IART's -13.7%, ROIC -36.1% vs 1.7%

IART vs NTRA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

IARTIntegra LifeSciences Holdings Corporation
FY 2025
Codman Specialty Surgical
73.4%$1.2B
Tissue Technologies
26.6%$435M
NTRANatera, Inc.
FY 2025
Product
99.6%$2.3B
Licensing and other
0.4%$10M

IART vs NTRA — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLNTRALAGGINGIART

Income & Cash Flow (Last 12 Months)

NTRA leads this category, winning 5 of 6 comparable metrics.

NTRA and IART operate at a comparable scale, with $2.3B and $1.6B in trailing revenue. NTRA is the more profitable business, keeping -9.0% of every revenue dollar as net income compared to IART's -30.1%. On growth, NTRA holds the edge at +39.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricIART logoIARTIntegra LifeScien…NTRA logoNTRANatera, Inc.
RevenueTrailing 12 months$1.6B$2.3B
EBITDAEarnings before interest/tax$209M-$310M
Net IncomeAfter-tax profit-$496M-$208M
Free Cash FlowCash after capex-$10M$97M
Gross MarginGross profit ÷ Revenue+39.6%+64.8%
Operating MarginEBIT ÷ Revenue+5.8%-13.4%
Net MarginNet income ÷ Revenue-30.1%-9.0%
FCF MarginFCF ÷ Revenue-0.6%+4.2%
Rev. Growth (YoY)Latest quarter vs prior year+2.4%+39.8%
EPS Growth (YoY)Latest quarter vs prior year+81.8%+185.4%
NTRA leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

IART leads this category, winning 2 of 3 comparable metrics.
MetricIART logoIARTIntegra LifeScien…NTRA logoNTRANatera, Inc.
Market CapShares × price$1.1B$31.2B
Enterprise ValueMkt cap + debt − cash$2.9B$30.3B
Trailing P/EPrice ÷ TTM EPS-2.01x-144.62x
Forward P/EPrice ÷ next-FY EPS est.5.77x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple13.01x
Price / SalesMarket cap ÷ Revenue0.65x13.51x
Price / BookPrice ÷ Book value/share1.00x17.55x
Price / FCFMarket cap ÷ FCF285.53x
IART leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

NTRA leads this category, winning 5 of 8 comparable metrics.

NTRA delivers a -15.3% return on equity — every $100 of shareholder capital generates $-15 in annual profit, vs $-48 for IART. NTRA carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to IART's 1.95x.

MetricIART logoIARTIntegra LifeScien…NTRA logoNTRANatera, Inc.
ROE (TTM)Return on equity-47.6%-15.3%
ROA (TTM)Return on assets-13.7%-10.6%
ROICReturn on invested capital+1.7%-36.1%
ROCEReturn on capital employed+2.2%-18.3%
Piotroski ScoreFundamental quality 0–955
Debt / EquityFinancial leverage1.95x0.13x
Net DebtTotal debt minus cash$1.8B-$862M
Cash & Equiv.Liquid assets$235M$1.1B
Total DebtShort + long-term debt$2.0B$214M
Interest CoverageEBIT ÷ Interest expense-10.36x-25.21x
NTRA leads this category, winning 5 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

NTRA leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in NTRA five years ago would be worth $21,587 today (with dividends reinvested), compared to $1,827 for IART. Over the past 12 months, NTRA leads with a +37.3% total return vs IART's +6.5%. The 3-year compound annual growth rate (CAGR) favors NTRA at 60.6% vs IART's -35.4% — a key indicator of consistent wealth creation.

MetricIART logoIARTIntegra LifeScien…NTRA logoNTRANatera, Inc.
YTD ReturnYear-to-date+12.9%-3.9%
1-Year ReturnPast 12 months+6.5%+37.3%
3-Year ReturnCumulative with dividends-73.1%+314.0%
5-Year ReturnCumulative with dividends-81.7%+115.9%
10-Year ReturnCumulative with dividends-63.0%+2089.4%
CAGR (3Y)Annualised 3-year return-35.4%+60.6%
NTRA leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

NTRA leads this category, winning 2 of 2 comparable metrics.

NTRA is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than IART's 2.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NTRA currently trades 85.7% from its 52-week high vs IART's 82.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricIART logoIARTIntegra LifeScien…NTRA logoNTRANatera, Inc.
Beta (5Y)Sensitivity to S&P 5002.34x1.26x
52-Week HighHighest price in past year$16.49$256.36
52-Week LowLowest price in past year$8.70$131.81
% of 52W HighCurrent price vs 52-week peak+82.2%+85.7%
RSI (14)Momentum oscillator 0–10075.957.1
Avg Volume (50D)Average daily shares traded858K1.3M
NTRA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates IART as "Buy" and NTRA as "Buy". Consensus price targets imply 19.4% upside for NTRA (target: $263) vs -11.5% for IART (target: $12).

MetricIART logoIARTIntegra LifeScien…NTRA logoNTRANatera, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$12.00$262.50
# AnalystsCovering analysts2627
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap+0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

NTRA leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IART leads in 1 (Valuation Metrics).

Best OverallNatera, Inc. (NTRA)Leads 4 of 6 categories
Loading custom metrics...

IART vs NTRA: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is IART or NTRA a better buy right now?

For growth investors, Natera, Inc.

(NTRA) is the stronger pick with 35. 9% revenue growth year-over-year, versus 1. 5% for Integra LifeSciences Holdings Corporation (IART). Analysts rate Integra LifeSciences Holdings Corporation (IART) a "Buy" — based on 26 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — IART or NTRA?

Over the past 5 years, Natera, Inc.

(NTRA) delivered a total return of +115. 9%, compared to -81. 7% for Integra LifeSciences Holdings Corporation (IART). Over 10 years, the gap is even starker: NTRA returned +20. 9% versus IART's -63. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — IART or NTRA?

By beta (market sensitivity over 5 years), Natera, Inc.

(NTRA) is the lower-risk stock at 1. 26β versus Integra LifeSciences Holdings Corporation's 2. 34β — meaning IART is approximately 86% more volatile than NTRA relative to the S&P 500. On balance sheet safety, Natera, Inc. (NTRA) carries a lower debt/equity ratio of 13% versus 195% for Integra LifeSciences Holdings Corporation — giving it more financial flexibility in a downturn.

04

Which is growing faster — IART or NTRA?

By revenue growth (latest reported year), Natera, Inc.

(NTRA) is pulling ahead at 35. 9% versus 1. 5% for Integra LifeSciences Holdings Corporation (IART). On earnings-per-share growth, the picture is similar: Natera, Inc. grew EPS 0. 7% year-over-year, compared to -73. 6% for Integra LifeSciences Holdings Corporation. Over a 3-year CAGR, NTRA leads at 41. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — IART or NTRA?

Natera, Inc.

(NTRA) is the more profitable company, earning -9. 0% net margin versus -31. 6% for Integra LifeSciences Holdings Corporation — meaning it keeps -9. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IART leads at 4. 2% versus -13. 4% for NTRA. At the gross margin level — before operating expenses — NTRA leads at 64. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is IART or NTRA more undervalued right now?

Analyst consensus price targets imply the most upside for NTRA: 19.

4% to $262. 50.

07

Which pays a better dividend — IART or NTRA?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is IART or NTRA better for a retirement portfolio?

For long-horizon retirement investors, Natera, Inc.

(NTRA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 26)). Integra LifeSciences Holdings Corporation (IART) carries a higher beta of 2. 34 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (NTRA: +20. 9%, IART: -63. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between IART and NTRA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: IART is a small-cap quality compounder stock; NTRA is a mid-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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IART

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 23%
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NTRA

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 19%
  • Gross Margin > 38%
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Revenue Growth>
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(IART: 2.4% · NTRA: 39.8%)

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