Biotechnology
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Side-by-side financial analysisStock Comparison
IKT vs LLY vs BIIB vs CRL vs IQV
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Medical - Diagnostics & Research
Medical - Diagnostics & Research
IKT vs LLY vs BIIB vs CRL vs IQV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General | Medical - Diagnostics & Research | Medical - Diagnostics & Research |
| Market Cap | $119M | $1.07T | $29.53B | $9.03B | $30.79B |
| Revenue (TTM) | $0.00 | $72.25B | $9.86B | $4.03B | $16.63B |
| Net Income (TTM) | $-51M | $25.27B | $1.37B | $-185M | $1.39B |
| Gross Margin | — | 83.5% | 69.8% | 31.9% | 26.1% |
| Operating Margin | — | 45.9% | 15.6% | 11.8% | 13.9% |
| Forward P/E | — | 30.9x | 13.7x | 16.9x | 14.2x |
| Total Debt | $0.00 | $42.50B | $6.95B | $3.07B | $16.17B |
| Cash & Equiv. | $139M | $7.16B | $3.01B | $214M | $1.98B |
IKT vs LLY vs BIIB vs CRL vs IQV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Dec 20 | Jun 26 | Return |
|---|---|---|---|
| Inhibikase Therapeu… (IKT) | 100 | 4.0 | -96.0% |
| Eli Lilly and Compa… (LLY) | 100 | 671.0 | +571.0% |
| Biogen Inc. (BIIB) | 100 | 81.7 | -18.3% |
| Charles River Labor… (CRL) | 100 | 75.0 | -25.0% |
| IQVIA Holdings Inc. (IQV) | 100 | 101.3 | +1.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: IKT vs LLY vs BIIB vs CRL vs IQV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
IKT ranks third and is worth considering specifically for growth.
- 129.4% revenue growth vs CRL's -0.9%
LLY carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 11 yrs, beta 0.53, yield 0.5%
- Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
- 14.8% 10Y total return vs IQV's 177.5%
- 35.0% margin vs CRL's -4.6%
BIIB is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 0.40, Low D/E 38.1%, current ratio 2.68x
- Beta 0.40, current ratio 2.68x
- Lower P/E (13.7x vs 16.9x)
- Beta 0.40 vs IKT's 1.92
CRL lags the leaders in this set but could rank higher in a more targeted comparison.
IQV is the clearest fit if your priority is valuation efficiency.
- PEG 0.35 vs LLY's 1.07
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 129.4% revenue growth vs CRL's -0.9% | |
| Value | Lower P/E (13.7x vs 16.9x) | |
| Quality / Margins | 35.0% margin vs CRL's -4.6% | |
| Stability / Safety | Beta 0.40 vs IKT's 1.92 | |
| Dividends | 0.5% yield; 11-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +51.2% vs IKT's -12.6% | |
| Efficiency (ROA) | 22.7% ROA vs IKT's -39.0%, ROIC 41.8% vs -108.0% |
IKT vs LLY vs BIIB vs CRL vs IQV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
IKT vs LLY vs BIIB vs CRL vs IQV — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
LLY leads in 4 of 6 categories
BIIB leads 2 • IKT leads 0 • CRL leads 0 • IQV leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
LLY leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
LLY and IKT operate at a comparable scale, with $72.2B and $0 in trailing revenue. LLY is the more profitable business, keeping 35.0% of every revenue dollar as net income compared to CRL's -4.6%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $72.2B | $9.9B | $4.0B | $16.6B |
| EBITDAEarnings before interest/tax | -$55M | $34.7B | $2.4B | $824M | $3.5B |
| Net IncomeAfter-tax profit | -$51M | $25.3B | $1.4B | -$185M | $1.4B |
| Free Cash FlowCash after capex | -$36M | $13.6B | $2.6B | $391M | $2.7B |
| Gross MarginGross profit ÷ Revenue | — | +83.5% | +69.8% | +31.9% | +26.1% |
| Operating MarginEBIT ÷ Revenue | — | +45.9% | +15.6% | +11.8% | +13.9% |
| Net MarginNet income ÷ Revenue | — | +35.0% | +13.9% | -4.6% | +8.3% |
| FCF MarginFCF ÷ Revenue | — | +18.8% | +26.6% | +9.7% | +16.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +55.5% | +1.9% | +1.2% | +8.4% |
| EPS Growth (YoY)Latest quarter vs prior year | -13.3% | +169.9% | +31.1% | -160.0% | +15.0% |
Valuation Metrics
BIIB leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 22.7x trailing earnings, BIIB trades at a 54% valuation discount to LLY's 49.4x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.57x vs LLY's 1.71x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $119M | $1.07T | $29.5B | $9.0B | $30.8B |
| Enterprise ValueMkt cap + debt − cash | -$21M | $1.11T | $33.5B | $11.9B | $45.0B |
| Trailing P/EPrice ÷ TTM EPS | -3.41x | 49.37x | 22.66x | -64.44x | 23.15x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 30.95x | 13.69x | 16.90x | 14.16x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.71x | — | — | 0.57x |
| EV / EBITDAEnterprise value multiple | — | 35.38x | 11.90x | 13.04x | 13.11x |
| Price / SalesMarket cap ÷ Revenue | — | 16.42x | 3.01x | 2.25x | 1.89x |
| Price / BookPrice ÷ Book value/share | 0.95x | 38.34x | 1.61x | 2.89x | 4.75x |
| Price / FCFMarket cap ÷ FCF | — | 119.31x | 14.40x | 17.42x | 15.01x |
Profitability & Efficiency
LLY leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
LLY delivers a 101.2% return on equity — every $100 of shareholder capital generates $101 in annual profit, vs $-41 for IKT. BIIB carries lower financial leverage with a 0.38x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), LLY scores 8/9 vs IKT's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -41.3% | +101.2% | +7.5% | -5.7% | +22.1% |
| ROA (TTM)Return on assets | -39.0% | +22.7% | +4.7% | -2.5% | +4.7% |
| ROICReturn on invested capital | -108.0% | +41.8% | +6.5% | +6.3% | +8.7% |
| ROCEReturn on capital employed | -38.8% | +46.6% | +7.7% | +8.1% | +11.0% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 8 | 5 | 4 | 4 |
| Debt / EquityFinancial leverage | — | 1.60x | 0.38x | 0.95x | 2.44x |
| Net DebtTotal debt minus cash | -$139M | $35.3B | $3.9B | $2.9B | $14.2B |
| Cash & Equiv.Liquid assets | $139M | $7.2B | $3.0B | $214M | $2.0B |
| Total DebtShort + long-term debt | $0 | $42.5B | $6.9B | $3.1B | $16.2B |
| Interest CoverageEBIT ÷ Interest expense | — | 35.68x | 6.91x | 4.29x | 3.10x |
Total Returns (Dividends Reinvested)
LLY leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LLY five years ago would be worth $51,207 today (with dividends reinvested), compared to $573 for IKT. Over the past 12 months, BIIB leads with a +51.2% total return vs IKT's -12.6%. The 3-year compound annual growth rate (CAGR) favors LLY at 37.2% vs IKT's -26.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -14.4% | +5.2% | +12.5% | -7.4% | -19.5% |
| 1-Year ReturnPast 12 months | -12.6% | +40.3% | +51.2% | +23.5% | +14.0% |
| 3-Year ReturnCumulative with dividends | -59.5% | +158.2% | -36.2% | -8.7% | -14.4% |
| 5-Year ReturnCumulative with dividends | -94.3% | +412.1% | -50.7% | -47.2% | -25.8% |
| 10-Year ReturnCumulative with dividends | -97.2% | +1484.6% | -18.1% | +122.4% | +177.5% |
| CAGR (3Y)Annualised 3-year return | -26.0% | +37.2% | -13.9% | -3.0% | -5.0% |
Risk & Volatility
BIIB leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
BIIB is the less volatile stock with a 0.40 beta — it tends to amplify market swings less than IKT's 1.92 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BIIB currently trades 97.1% from its 52-week high vs IQV's 73.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.92x | 0.53x | 0.40x | 1.39x | 1.16x |
| 52-Week HighHighest price in past year | $2.26 | $1182.73 | $205.97 | $228.88 | $247.05 |
| 52-Week LowLowest price in past year | $1.33 | $623.78 | $121.05 | $143.06 | $153.01 |
| % of 52W HighCurrent price vs 52-week peak | +73.9% | +95.8% | +97.1% | +81.9% | +73.5% |
| RSI (14)Momentum oscillator 0–100 | 44.1 | 70.0 | 57.5 | 60.8 | 54.4 |
| Avg Volume (50D)Average daily shares traded | 787K | 2.6M | 1.1M | 767K | 1.5M |
Analyst Outlook
LLY leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: IKT as "Hold", LLY as "Buy", BIIB as "Buy", CRL as "Buy", IQV as "Buy". Consensus price targets imply 199.4% upside for IKT (target: $5) vs 9.1% for BIIB (target: $218). LLY is the only dividend payer here at 0.53% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $5.00 | $1268.94 | $218.16 | $213.17 | $222.22 |
| # AnalystsCovering analysts | 2 | 45 | 48 | 37 | 44 |
| Dividend YieldAnnual dividend ÷ price | — | +0.5% | — | — | — |
| Dividend StreakConsecutive years of raises | — | 11 | 0 | 1 | 2 |
| Dividend / ShareAnnual DPS | — | $6.00 | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.4% | 0.0% | +4.0% | +4.0% |
LLY leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BIIB leads in 2 (Valuation Metrics, Risk & Volatility).
IKT vs LLY vs BIIB vs CRL vs IQV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is IKT or LLY or BIIB or CRL or IQV a better buy right now?
For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.
7% revenue growth year-over-year, versus -0. 9% for Charles River Laboratories International, Inc. (CRL). Biogen Inc. (BIIB) offers the better valuation at 22. 7x trailing P/E (13. 7x forward), making it the more compelling value choice. Analysts rate Eli Lilly and Company (LLY) a "Buy" — based on 45 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — IKT or LLY or BIIB or CRL or IQV?
On trailing P/E, Biogen Inc.
(BIIB) is the cheapest at 22. 7x versus Eli Lilly and Company at 49. 4x. On forward P/E, Biogen Inc. is actually cheaper at 13. 7x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 35x versus Eli Lilly and Company's 1. 07x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — IKT or LLY or BIIB or CRL or IQV?
Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +412.
1%, compared to -94. 3% for Inhibikase Therapeutics, Inc. (IKT). Over 10 years, the gap is even starker: LLY returned +1485% versus IKT's -97. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — IKT or LLY or BIIB or CRL or IQV?
By beta (market sensitivity over 5 years), Biogen Inc.
(BIIB) is the lower-risk stock at 0. 40β versus Inhibikase Therapeutics, Inc. 's 1. 92β — meaning IKT is approximately 373% more volatile than BIIB relative to the S&P 500. On balance sheet safety, Biogen Inc. (BIIB) carries a lower debt/equity ratio of 38% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — IKT or LLY or BIIB or CRL or IQV?
By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.
7% versus -0. 9% for Charles River Laboratories International, Inc. (CRL). On earnings-per-share growth, the picture is similar: Eli Lilly and Company grew EPS 96. 0% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — IKT or LLY or BIIB or CRL or IQV?
Eli Lilly and Company (LLY) is the more profitable company, earning 31.
7% net margin versus -3. 6% for Charles River Laboratories International, Inc. — meaning it keeps 31. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus 0. 0% for IKT. At the gross margin level — before operating expenses — LLY leads at 83. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is IKT or LLY or BIIB or CRL or IQV more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 35x versus Eli Lilly and Company's 1. 07x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Biogen Inc. (BIIB) trades at 13. 7x forward P/E versus 30. 9x for Eli Lilly and Company — 17. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for IKT: 199. 4% to $5. 00.
08Which pays a better dividend — IKT or LLY or BIIB or CRL or IQV?
In this comparison, LLY (0.
5% yield) pays a dividend. IKT, BIIB, CRL, IQV do not pay a meaningful dividend and should not be held primarily for income.
09Is IKT or LLY or BIIB or CRL or IQV better for a retirement portfolio?
For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
53), 0. 5% yield, +1485% 10Y return). Inhibikase Therapeutics, Inc. (IKT) carries a higher beta of 1. 92 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (LLY: +1485%, IKT: -97. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between IKT and LLY and BIIB and CRL and IQV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: IKT is a small-cap quality compounder stock; LLY is a mega-cap high-growth stock; BIIB is a mid-cap quality compounder stock; CRL is a small-cap quality compounder stock; IQV is a mid-cap quality compounder stock. LLY pays a dividend while IKT, BIIB, CRL, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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