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Stock Comparison

IMTX vs CRIS

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
IMTX
Immatics N.V.

Biotechnology

HealthcareNASDAQ • DE
Market Cap$1.49B
5Y Perf.-15.1%
CRIS
Curis, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$76M
5Y Perf.-96.6%

IMTX vs CRIS — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
IMTX logoIMTX
CRIS logoCRIS
IndustryBiotechnologyBiotechnology
Market Cap$1.49B$76M
Revenue (TTM)$85M$9M
Net Income (TTM)$-116M$-8M
Gross Margin100.0%99.5%
Operating Margin-167.8%-348.4%
Forward P/E67.7x
Total Debt$16M$2M
Cash & Equiv.$237M$5M

IMTX vs CRISLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

IMTX
CRIS
StockMay 20May 26Return
Immatics N.V. (IMTX)10084.9-15.1%
Curis, Inc. (CRIS)1003.4-96.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: IMTX vs CRIS

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: IMTX leads in 4 of 6 categories, making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. Curis, Inc. is the stronger pick specifically for profitability and margin quality. As sector peers, any of these can serve as alternatives in the same allocation.
IMTX
Immatics N.V.
The Income Pick

IMTX carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 1.63
  • Rev growth 188.6%, EPS growth 111.7%, 3Y rev CAGR 64.9%
  • 16.0% 10Y total return vs CRIS's -99.7%
Best for: income & stability and growth exposure
CRIS
Curis, Inc.
The Quality Compounder

CRIS is the clearest fit if your priority is quality.

  • -80.3% margin vs IMTX's -136.7%
Best for: quality
See the full category breakdown
CategoryWinnerWhy
GrowthIMTX logoIMTX188.6% revenue growth vs CRIS's -13.4%
Quality / MarginsCRIS logoCRIS-80.3% margin vs IMTX's -136.7%
Stability / SafetyIMTX logoIMTXBeta 1.63 vs CRIS's 1.87, lower leverage
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)IMTX logoIMTX+153.8% vs CRIS's -72.0%
Efficiency (ROA)IMTX logoIMTX-22.3% ROA vs CRIS's -26.1%

IMTX vs CRIS — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

IMTXImmatics N.V.

Segment breakdown not available.

CRISCuris, Inc.
FY 2025
Reportable Segment
100.0%$9M

IMTX vs CRIS — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLIMTXLAGGINGCRIS

Income & Cash Flow (Last 12 Months)

Evenly matched — IMTX and CRIS each lead in 3 of 6 comparable metrics.

IMTX is the larger business by revenue, generating $85M annually — 9.0x CRIS's $9M. CRIS is the more profitable business, keeping -80.3% of every revenue dollar as net income compared to IMTX's -136.7%. On growth, CRIS holds the edge at -66.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricIMTX logoIMTXImmatics N.V.CRIS logoCRISCuris, Inc.
RevenueTrailing 12 months$85M$9M
EBITDAEarnings before interest/tax-$130M-$33M
Net IncomeAfter-tax profit-$116M-$8M
Free Cash FlowCash after capex-$184M-$27M
Gross MarginGross profit ÷ Revenue+100.0%+99.5%
Operating MarginEBIT ÷ Revenue-167.8%-3.5%
Net MarginNet income ÷ Revenue-136.7%-80.3%
FCF MarginFCF ÷ Revenue-2.2%-2.9%
Rev. Growth (YoY)Latest quarter vs prior year-89.7%-66.0%
EPS Growth (YoY)Latest quarter vs prior year-2.8%+198.4%
Evenly matched — IMTX and CRIS each lead in 3 of 6 comparable metrics.

Valuation Metrics

CRIS leads this category, winning 2 of 3 comparable metrics.
MetricIMTX logoIMTXImmatics N.V.CRIS logoCRISCuris, Inc.
Market CapShares × price$1.5B$76M
Enterprise ValueMkt cap + debt − cash$1.2B$73M
Trailing P/EPrice ÷ TTM EPS67.71x-0.99x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue8.16x8.04x
Price / BookPrice ÷ Book value/share1.76x13.91x
Price / FCFMarket cap ÷ FCF
CRIS leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

IMTX leads this category, winning 6 of 8 comparable metrics.

IMTX delivers a -27.8% return on equity — every $100 of shareholder capital generates $-28 in annual profit, vs $-139 for CRIS. IMTX carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to CRIS's 0.30x. On the Piotroski fundamental quality scale (0–9), IMTX scores 6/9 vs CRIS's 3/9, reflecting solid financial health.

MetricIMTX logoIMTXImmatics N.V.CRIS logoCRISCuris, Inc.
ROE (TTM)Return on equity-27.8%-138.8%
ROA (TTM)Return on assets-22.3%-26.1%
ROICReturn on invested capital-15.4%
ROCEReturn on capital employed-7.9%-2.3%
Piotroski ScoreFundamental quality 0–963
Debt / EquityFinancial leverage0.03x0.30x
Net DebtTotal debt minus cash-$221M-$3M
Cash & Equiv.Liquid assets$237M$5M
Total DebtShort + long-term debt$16M$2M
Interest CoverageEBIT ÷ Interest expense-124.10x-107.35x
IMTX leads this category, winning 6 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

IMTX leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in IMTX five years ago would be worth $9,670 today (with dividends reinvested), compared to $28 for CRIS. Over the past 12 months, IMTX leads with a +153.8% total return vs CRIS's -72.0%. The 3-year compound annual growth rate (CAGR) favors IMTX at 4.3% vs CRIS's -67.0% — a key indicator of consistent wealth creation.

MetricIMTX logoIMTXImmatics N.V.CRIS logoCRISCuris, Inc.
YTD ReturnYear-to-date+6.6%-41.1%
1-Year ReturnPast 12 months+153.8%-72.0%
3-Year ReturnCumulative with dividends+13.3%-96.4%
5-Year ReturnCumulative with dividends-3.3%-99.7%
10-Year ReturnCumulative with dividends+16.0%-99.7%
CAGR (3Y)Annualised 3-year return+4.3%-67.0%
IMTX leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

IMTX leads this category, winning 2 of 2 comparable metrics.

IMTX is the less volatile stock with a 1.63 beta — it tends to amplify market swings less than CRIS's 1.87 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMTX currently trades 89.8% from its 52-week high vs CRIS's 18.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricIMTX logoIMTXImmatics N.V.CRIS logoCRISCuris, Inc.
Beta (5Y)Sensitivity to S&P 5001.58x1.92x
52-Week HighHighest price in past year$12.41$3.13
52-Week LowLowest price in past year$3.94$0.49
% of 52W HighCurrent price vs 52-week peak+89.8%+18.4%
RSI (14)Momentum oscillator 0–10060.948.9
Avg Volume (50D)Average daily shares traded448K444K
IMTX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricIMTX logoIMTXImmatics N.V.CRIS logoCRISCuris, Inc.
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$21.00
# AnalystsCovering analysts8
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

IMTX leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). CRIS leads in 1 (Valuation Metrics). 1 tied.

Best OverallImmatics N.V. (IMTX)Leads 3 of 6 categories
Loading custom metrics...

IMTX vs CRIS: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is IMTX or CRIS a better buy right now?

For growth investors, Immatics N.

V. (IMTX) is the stronger pick with 188. 6% revenue growth year-over-year, versus -13. 4% for Curis, Inc. (CRIS). Immatics N. V. (IMTX) offers the better valuation at 67. 7x trailing P/E, making it the more compelling value choice. Analysts rate Immatics N. V. (IMTX) a "Buy" — based on 8 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — IMTX or CRIS?

Over the past 5 years, Immatics N.

V. (IMTX) delivered a total return of -3. 3%, compared to -99. 7% for Curis, Inc. (CRIS). Over 10 years, the gap is even starker: IMTX returned +18. 4% versus CRIS's -99. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — IMTX or CRIS?

By beta (market sensitivity over 5 years), Immatics N.

V. (IMTX) is the lower-risk stock at 1. 58β versus Curis, Inc. 's 1. 92β — meaning CRIS is approximately 22% more volatile than IMTX relative to the S&P 500. On balance sheet safety, Immatics N. V. (IMTX) carries a lower debt/equity ratio of 3% versus 30% for Curis, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — IMTX or CRIS?

By revenue growth (latest reported year), Immatics N.

V. (IMTX) is pulling ahead at 188. 6% versus -13. 4% for Curis, Inc. (CRIS). On earnings-per-share growth, the picture is similar: Immatics N. V. grew EPS 111. 7% year-over-year, compared to 91. 6% for Curis, Inc.. Over a 3-year CAGR, IMTX leads at 64. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — IMTX or CRIS?

Immatics N.

V. (IMTX) is the more profitable company, earning 9. 8% net margin versus -80. 3% for Curis, Inc. — meaning it keeps 9. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMTX leads at -24. 8% versus -348. 4% for CRIS. At the gross margin level — before operating expenses — IMTX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — IMTX or CRIS?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is IMTX or CRIS better for a retirement portfolio?

For long-horizon retirement investors, Immatics N.

V. (IMTX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Curis, Inc. (CRIS) carries a higher beta of 1. 92 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMTX: +18. 4%, CRIS: -99. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between IMTX and CRIS?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: IMTX is a small-cap high-growth stock; CRIS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 59%
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