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IMTX vs CRIS
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
IMTX vs CRIS — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $1.49B | $76M |
| Revenue (TTM) | $85M | $9M |
| Net Income (TTM) | $-116M | $-8M |
| Gross Margin | 100.0% | 99.5% |
| Operating Margin | -167.8% | -348.4% |
| Forward P/E | 67.7x | — |
| Total Debt | $16M | $2M |
| Cash & Equiv. | $237M | $5M |
IMTX vs CRIS — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Immatics N.V. (IMTX) | 100 | 84.9 | -15.1% |
| Curis, Inc. (CRIS) | 100 | 3.4 | -96.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: IMTX vs CRIS
Each card shows where this stock fits in a portfolio — not just who wins on paper.
IMTX carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.63
- Rev growth 188.6%, EPS growth 111.7%, 3Y rev CAGR 64.9%
- 16.0% 10Y total return vs CRIS's -99.7%
CRIS is the clearest fit if your priority is quality.
- -80.3% margin vs IMTX's -136.7%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 188.6% revenue growth vs CRIS's -13.4% | |
| Quality / Margins | -80.3% margin vs IMTX's -136.7% | |
| Stability / Safety | Beta 1.63 vs CRIS's 1.87, lower leverage | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +153.8% vs CRIS's -72.0% | |
| Efficiency (ROA) | -22.3% ROA vs CRIS's -26.1% |
IMTX vs CRIS — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
IMTX vs CRIS — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
Evenly matched — IMTX and CRIS each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
IMTX is the larger business by revenue, generating $85M annually — 9.0x CRIS's $9M. CRIS is the more profitable business, keeping -80.3% of every revenue dollar as net income compared to IMTX's -136.7%. On growth, CRIS holds the edge at -66.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $85M | $9M |
| EBITDAEarnings before interest/tax | -$130M | -$33M |
| Net IncomeAfter-tax profit | -$116M | -$8M |
| Free Cash FlowCash after capex | -$184M | -$27M |
| Gross MarginGross profit ÷ Revenue | +100.0% | +99.5% |
| Operating MarginEBIT ÷ Revenue | -167.8% | -3.5% |
| Net MarginNet income ÷ Revenue | -136.7% | -80.3% |
| FCF MarginFCF ÷ Revenue | -2.2% | -2.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | -89.7% | -66.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -2.8% | +198.4% |
Valuation Metrics
CRIS leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $1.5B | $76M |
| Enterprise ValueMkt cap + debt − cash | $1.2B | $73M |
| Trailing P/EPrice ÷ TTM EPS | 67.71x | -0.99x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 8.16x | 8.04x |
| Price / BookPrice ÷ Book value/share | 1.76x | 13.91x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
IMTX leads this category, winning 6 of 8 comparable metrics.
Profitability & Efficiency
IMTX delivers a -27.8% return on equity — every $100 of shareholder capital generates $-28 in annual profit, vs $-139 for CRIS. IMTX carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to CRIS's 0.30x. On the Piotroski fundamental quality scale (0–9), IMTX scores 6/9 vs CRIS's 3/9, reflecting solid financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -27.8% | -138.8% |
| ROA (TTM)Return on assets | -22.3% | -26.1% |
| ROICReturn on invested capital | -15.4% | — |
| ROCEReturn on capital employed | -7.9% | -2.3% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 3 |
| Debt / EquityFinancial leverage | 0.03x | 0.30x |
| Net DebtTotal debt minus cash | -$221M | -$3M |
| Cash & Equiv.Liquid assets | $237M | $5M |
| Total DebtShort + long-term debt | $16M | $2M |
| Interest CoverageEBIT ÷ Interest expense | -124.10x | -107.35x |
Total Returns (Dividends Reinvested)
IMTX leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMTX five years ago would be worth $9,670 today (with dividends reinvested), compared to $28 for CRIS. Over the past 12 months, IMTX leads with a +153.8% total return vs CRIS's -72.0%. The 3-year compound annual growth rate (CAGR) favors IMTX at 4.3% vs CRIS's -67.0% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +6.6% | -41.1% |
| 1-Year ReturnPast 12 months | +153.8% | -72.0% |
| 3-Year ReturnCumulative with dividends | +13.3% | -96.4% |
| 5-Year ReturnCumulative with dividends | -3.3% | -99.7% |
| 10-Year ReturnCumulative with dividends | +16.0% | -99.7% |
| CAGR (3Y)Annualised 3-year return | +4.3% | -67.0% |
Risk & Volatility
IMTX leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
IMTX is the less volatile stock with a 1.63 beta — it tends to amplify market swings less than CRIS's 1.87 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMTX currently trades 89.8% from its 52-week high vs CRIS's 18.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.58x | 1.92x |
| 52-Week HighHighest price in past year | $12.41 | $3.13 |
| 52-Week LowLowest price in past year | $3.94 | $0.49 |
| % of 52W HighCurrent price vs 52-week peak | +89.8% | +18.4% |
| RSI (14)Momentum oscillator 0–100 | 60.9 | 48.9 |
| Avg Volume (50D)Average daily shares traded | 448K | 444K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | — |
| Price TargetConsensus 12-month target | $21.00 | — |
| # AnalystsCovering analysts | 8 | — |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
IMTX leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). CRIS leads in 1 (Valuation Metrics). 1 tied.
IMTX vs CRIS: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is IMTX or CRIS a better buy right now?
For growth investors, Immatics N.
V. (IMTX) is the stronger pick with 188. 6% revenue growth year-over-year, versus -13. 4% for Curis, Inc. (CRIS). Immatics N. V. (IMTX) offers the better valuation at 67. 7x trailing P/E, making it the more compelling value choice. Analysts rate Immatics N. V. (IMTX) a "Buy" — based on 8 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — IMTX or CRIS?
Over the past 5 years, Immatics N.
V. (IMTX) delivered a total return of -3. 3%, compared to -99. 7% for Curis, Inc. (CRIS). Over 10 years, the gap is even starker: IMTX returned +18. 4% versus CRIS's -99. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — IMTX or CRIS?
By beta (market sensitivity over 5 years), Immatics N.
V. (IMTX) is the lower-risk stock at 1. 58β versus Curis, Inc. 's 1. 92β — meaning CRIS is approximately 22% more volatile than IMTX relative to the S&P 500. On balance sheet safety, Immatics N. V. (IMTX) carries a lower debt/equity ratio of 3% versus 30% for Curis, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — IMTX or CRIS?
By revenue growth (latest reported year), Immatics N.
V. (IMTX) is pulling ahead at 188. 6% versus -13. 4% for Curis, Inc. (CRIS). On earnings-per-share growth, the picture is similar: Immatics N. V. grew EPS 111. 7% year-over-year, compared to 91. 6% for Curis, Inc.. Over a 3-year CAGR, IMTX leads at 64. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — IMTX or CRIS?
Immatics N.
V. (IMTX) is the more profitable company, earning 9. 8% net margin versus -80. 3% for Curis, Inc. — meaning it keeps 9. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMTX leads at -24. 8% versus -348. 4% for CRIS. At the gross margin level — before operating expenses — IMTX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — IMTX or CRIS?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is IMTX or CRIS better for a retirement portfolio?
For long-horizon retirement investors, Immatics N.
V. (IMTX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Curis, Inc. (CRIS) carries a higher beta of 1. 92 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMTX: +18. 4%, CRIS: -99. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between IMTX and CRIS?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: IMTX is a small-cap high-growth stock; CRIS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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