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INBX vs KYMR vs IMVT vs PRAX vs CRL

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
INBX
Inhibrx Biosciences, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.96B
5Y Perf.+688.4%
KYMR
Kymera Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.03B
5Y Perf.+139.2%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.88B
5Y Perf.-33.7%
PRAX
Praxis Precision Medicines, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$9.53B
5Y Perf.-37.1%
CRL
Charles River Laboratories International, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$8.76B
5Y Perf.-22.0%

INBX vs KYMR vs IMVT vs PRAX vs CRL — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
INBX logoINBX
KYMR logoKYMR
IMVT logoIMVT
PRAX logoPRAX
CRL logoCRL
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyMedical - Diagnostics & Research
Market Cap$1.96B$7.03B$5.88B$9.53B$8.76B
Revenue (TTM)$1M$51M$0.00$0.00$4.03B
Net Income (TTM)$-140M$-315M$-464M$-327M$-185M
Gross Margin-47.6%33.2%31.9%
Operating Margin-103.9%-7.0%11.8%
Forward P/E16.0x
Total Debt$107M$82M$98K$110K$3.07B
Cash & Equiv.$124M$357M$714M$357M$214M

INBX vs KYMR vs IMVT vs PRAX vs CRLLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

INBX
KYMR
IMVT
PRAX
CRL
StockOct 20May 26Return
Inhibrx Biosciences… (INBX)100788.4+688.4%
Kymera Therapeutics… (KYMR)100239.2+139.2%
Immunovant, Inc. (IMVT)10066.3-33.7%
Praxis Precision Me… (PRAX)10062.9-37.1%
Charles River Labor… (CRL)10078.0-22.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: INBX vs KYMR vs IMVT vs PRAX vs CRL

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INBX leads in 2 of 6 categories (5-stock set), making it the strongest pick for growth and revenue expansion and recent price momentum and sentiment. Kymera Therapeutics, Inc. is the stronger pick specifically for capital preservation and lower volatility. IMVT and CRL also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
INBX
Inhibrx Biosciences, Inc.
The Growth Play

INBX carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth 5.5%, EPS growth -107.8%, 3Y rev CAGR -16.0%
  • 5.6% 10Y total return vs IMVT's 190.9%
  • 5.5% revenue growth vs PRAX's -100.0%
  • +10.9% vs CRL's +25.7%
Best for: growth exposure and long-term compounding
KYMR
Kymera Therapeutics, Inc.
The Defensive Pick

KYMR is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.

  • Lower volatility, beta 1.03, Low D/E 5.2%, current ratio 10.47x
  • Beta 1.03, current ratio 10.47x
  • Beta 1.03 vs INBX's 1.99, lower leverage
Best for: sleep-well-at-night and defensive
IMVT
Immunovant, Inc.
The Quality Compounder

IMVT ranks third and is worth considering specifically for quality.

  • 3.2% margin vs INBX's -107.7%
Best for: quality
PRAX
Praxis Precision Medicines, Inc.
The Healthcare Pick

Among these 5 stocks, PRAX doesn't own a clear edge in any measured category.

Best for: healthcare exposure
CRL
Charles River Laboratories International, Inc.
The Income Pick

CRL is the clearest fit if your priority is income & stability.

  • Dividend streak 1 yrs, beta 1.44
  • -2.5% ROA vs INBX's -71.9%
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthINBX logoINBX5.5% revenue growth vs PRAX's -100.0%
Quality / MarginsIMVT logoIMVT3.2% margin vs INBX's -107.7%
Stability / SafetyKYMR logoKYMRBeta 1.03 vs INBX's 1.99, lower leverage
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)INBX logoINBX+10.9% vs CRL's +25.7%
Efficiency (ROA)CRL logoCRL-2.5% ROA vs INBX's -71.9%

INBX vs KYMR vs IMVT vs PRAX vs CRL — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

INBXInhibrx Biosciences, Inc.
FY 2025
License, Non-Affiliate
100.0%$1M
KYMRKymera Therapeutics, Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

PRAXPraxis Precision Medicines, Inc.
FY 2024
License
76.8%$9M
Upfront Payment
23.2%$3M
CRLCharles River Laboratories International, Inc.
FY 2025
Discovery and Safety Assessment
59.8%$2.4B
Research Models and Services
21.1%$846M
Manufacturing Support
19.1%$766M

INBX vs KYMR vs IMVT vs PRAX vs CRL — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCRLLAGGINGPRAX

Income & Cash Flow (Last 12 Months)

CRL leads this category, winning 3 of 6 comparable metrics.

CRL and PRAX operate at a comparable scale, with $4.0B and $0 in trailing revenue. CRL is the more profitable business, keeping -4.6% of every revenue dollar as net income compared to INBX's -107.7%. On growth, KYMR holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricINBX logoINBXInhibrx Bioscienc…KYMR logoKYMRKymera Therapeuti…IMVT logoIMVTImmunovant, Inc.PRAX logoPRAXPraxis Precision …CRL logoCRLCharles River Lab…
RevenueTrailing 12 months$1M$51M$0$0$4.0B
EBITDAEarnings before interest/tax-$133M-$352M-$487M-$357M$824M
Net IncomeAfter-tax profit-$140M-$315M-$464M-$327M-$185M
Free Cash FlowCash after capex-$130M-$244M-$423M-$283M$391M
Gross MarginGross profit ÷ Revenue-47.6%+33.2%+31.9%
Operating MarginEBIT ÷ Revenue-103.9%-7.0%+11.8%
Net MarginNet income ÷ Revenue-107.7%-6.1%-4.6%
FCF MarginFCF ÷ Revenue-99.9%-4.7%+9.7%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%+55.5%+1.2%
EPS Growth (YoY)Latest quarter vs prior year+36.3%+13.4%+19.7%+2.7%-160.0%
CRL leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

CRL leads this category, winning 3 of 3 comparable metrics.
MetricINBX logoINBXInhibrx Bioscienc…KYMR logoKYMRKymera Therapeuti…IMVT logoIMVTImmunovant, Inc.PRAX logoPRAXPraxis Precision …CRL logoCRLCharles River Lab…
Market CapShares × price$2.0B$7.0B$5.9B$9.5B$8.8B
Enterprise ValueMkt cap + debt − cash$1.9B$6.8B$5.2B$9.2B$11.6B
Trailing P/EPrice ÷ TTM EPS-14.86x-23.33x-10.60x-24.48x-61.04x
Forward P/EPrice ÷ next-FY EPS est.16.00x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple12.75x
Price / SalesMarket cap ÷ Revenue1506.58x179.28x2.18x
Price / BookPrice ÷ Book value/share260.31x4.60x6.20x8.46x2.74x
Price / FCFMarket cap ÷ FCF16.90x
CRL leads this category, winning 3 of 3 comparable metrics.

Profitability & Efficiency

CRL leads this category, winning 6 of 9 comparable metrics.

CRL delivers a -5.7% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-3 for INBX. PRAX carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to INBX's 13.39x. On the Piotroski fundamental quality scale (0–9), KYMR scores 4/9 vs IMVT's 2/9, reflecting mixed financial health.

MetricINBX logoINBXInhibrx Bioscienc…KYMR logoKYMRKymera Therapeuti…IMVT logoIMVTImmunovant, Inc.PRAX logoPRAXPraxis Precision …CRL logoCRLCharles River Lab…
ROE (TTM)Return on equity-2.7%-25.0%-47.1%-43.0%-5.7%
ROA (TTM)Return on assets-71.9%-22.3%-44.1%-40.2%-2.5%
ROICReturn on invested capital-24.9%-65.0%+6.3%
ROCEReturn on capital employed-106.9%-27.2%-66.1%-49.3%+8.1%
Piotroski ScoreFundamental quality 0–924234
Debt / EquityFinancial leverage13.39x0.05x0.00x0.00x0.95x
Net DebtTotal debt minus cash-$17M-$275M-$714M-$357M$2.9B
Cash & Equiv.Liquid assets$124M$357M$714M$357M$214M
Total DebtShort + long-term debt$107M$82M$98,000$110,000$3.1B
Interest CoverageEBIT ÷ Interest expense-2119.53x4.29x
CRL leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

INBX leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in INBX five years ago would be worth $91,290 today (with dividends reinvested), compared to $5,336 for CRL. Over the past 12 months, INBX leads with a +1093.2% total return vs CRL's +25.7%. The 3-year compound annual growth rate (CAGR) favors PRAX at 174.0% vs CRL's -2.2% — a key indicator of consistent wealth creation.

MetricINBX logoINBXInhibrx Bioscienc…KYMR logoKYMRKymera Therapeuti…IMVT logoIMVTImmunovant, Inc.PRAX logoPRAXPraxis Precision …CRL logoCRLCharles River Lab…
YTD ReturnYear-to-date+79.0%+18.3%+11.7%+15.2%-12.3%
1-Year ReturnPast 12 months+1093.2%+179.8%+102.4%+767.1%+25.7%
3-Year ReturnCumulative with dividends+411.2%+210.3%+49.8%+1956.2%-6.5%
5-Year ReturnCumulative with dividends+812.9%+95.8%+84.4%-14.9%-46.6%
10-Year ReturnCumulative with dividends+555.4%+158.8%+190.9%-20.9%+114.0%
CAGR (3Y)Annualised 3-year return+72.3%+45.9%+14.4%+174.0%-2.2%
INBX leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — KYMR and IMVT each lead in 1 of 2 comparable metrics.

KYMR is the less volatile stock with a 1.03 beta — it tends to amplify market swings less than INBX's 1.99 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 96.2% from its 52-week high vs CRL's 77.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricINBX logoINBXInhibrx Bioscienc…KYMR logoKYMRKymera Therapeuti…IMVT logoIMVTImmunovant, Inc.PRAX logoPRAXPraxis Precision …CRL logoCRLCharles River Lab…
Beta (5Y)Sensitivity to S&P 5001.99x1.03x1.36x1.40x1.44x
52-Week HighHighest price in past year$155.29$103.00$30.09$356.00$228.88
52-Week LowLowest price in past year$10.84$28.06$13.36$35.21$132.58
% of 52W HighCurrent price vs 52-week peak+86.5%+83.6%+96.2%+92.7%+77.6%
RSI (14)Momentum oscillator 0–10062.750.550.653.357.4
Avg Volume (50D)Average daily shares traded340K583K1.4M376K792K
Evenly matched — KYMR and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

CRL leads this category, winning 1 of 1 comparable metric.

Analyst consensus: INBX as "Buy", KYMR as "Buy", IMVT as "Buy", PRAX as "Buy", CRL as "Buy". Consensus price targets imply 66.3% upside for PRAX (target: $549) vs 16.2% for CRL (target: $206).

MetricINBX logoINBXInhibrx Bioscienc…KYMR logoKYMRKymera Therapeuti…IMVT logoIMVTImmunovant, Inc.PRAX logoPRAXPraxis Precision …CRL logoCRLCharles River Lab…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$118.06$45.50$548.80$206.43
# AnalystsCovering analysts526231636
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises01
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+4.1%
CRL leads this category, winning 1 of 1 comparable metric.
Key Takeaway

CRL leads in 4 of 6 categories (Income & Cash Flow, Valuation Metrics). INBX leads in 1 (Total Returns). 1 tied.

Best OverallCharles River Laboratories … (CRL)Leads 4 of 6 categories
Loading custom metrics...

INBX vs KYMR vs IMVT vs PRAX vs CRL: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is INBX or KYMR or IMVT or PRAX or CRL a better buy right now?

For growth investors, Inhibrx Biosciences, Inc.

(INBX) is the stronger pick with 550. 0% revenue growth year-over-year, versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). Analysts rate Inhibrx Biosciences, Inc. (INBX) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — INBX or KYMR or IMVT or PRAX or CRL?

Over the past 5 years, Inhibrx Biosciences, Inc.

(INBX) delivered a total return of +812. 9%, compared to -46. 6% for Charles River Laboratories International, Inc. (CRL). Over 10 years, the gap is even starker: INBX returned +555. 4% versus PRAX's -20. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — INBX or KYMR or IMVT or PRAX or CRL?

By beta (market sensitivity over 5 years), Kymera Therapeutics, Inc.

(KYMR) is the lower-risk stock at 1. 03β versus Inhibrx Biosciences, Inc. 's 1. 99β — meaning INBX is approximately 94% more volatile than KYMR relative to the S&P 500. On balance sheet safety, Praxis Precision Medicines, Inc. (PRAX) carries a lower debt/equity ratio of 0% versus 13% for Inhibrx Biosciences, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — INBX or KYMR or IMVT or PRAX or CRL?

By revenue growth (latest reported year), Inhibrx Biosciences, Inc.

(INBX) is pulling ahead at 550. 0% versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). On earnings-per-share growth, the picture is similar: Kymera Therapeutics, Inc. grew EPS -23. 8% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, CRL leads at 0. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — INBX or KYMR or IMVT or PRAX or CRL?

Immunovant, Inc.

(IMVT) is the more profitable company, earning 0. 0% net margin versus -107. 7% for Inhibrx Biosciences, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CRL leads at 12. 6% versus -103. 9% for INBX. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is INBX or KYMR or IMVT or PRAX or CRL more undervalued right now?

Analyst consensus price targets imply the most upside for PRAX: 66.

3% to $548. 80.

07

Which pays a better dividend — INBX or KYMR or IMVT or PRAX or CRL?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is INBX or KYMR or IMVT or PRAX or CRL better for a retirement portfolio?

For long-horizon retirement investors, Kymera Therapeutics, Inc.

(KYMR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 03), +158. 8% 10Y return). Inhibrx Biosciences, Inc. (INBX) carries a higher beta of 1. 99 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KYMR: +158. 8%, INBX: +555. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between INBX and KYMR and IMVT and PRAX and CRL?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: INBX is a small-cap high-growth stock; KYMR is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; PRAX is a small-cap quality compounder stock; CRL is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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INBX

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