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Praxis Precision Medicines, Inc. (PRAX) Total Return Calculator with Dividends Reinvested

Praxis Precision Medicines, Inc.

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The total return for Praxis Precision Medicines, Inc. (PRAX) stock is +860.90% over the past 12 months. So far it's up 18.00% this year. The 5-year total return is -18.43%, meaning $10,000 invested in PRAX stock 5 years ago would be worth $8,157 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in PRAX 1 year ago, it would be worth $88,724 today — you'd have gained $78,724.

With Dividends Reinvested$88,724+787.24%

Price Only (No DRIP)$88,724+787.24%

Period2025-05-07 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in PRAX

1Y$96,090+$86,090 (+860.9%)860.9% CAGR

3Y$210,561+$200,561 (+2005.6%)176.1% CAGR

5Y$8,157-$1,843 (-18.4%)-4.0% CAGR

10Y$8,104-$1,896 (-19.0%)-2.1% CAGR

15Y$8,104-$1,896 (-19.0%)-1.4% CAGR

20Y$8,104-$1,896 (-19.0%)-1.0% CAGR

30Y$8,104-$1,896 (-19.0%)-0.7% CAGR

Praxis Precision Medicines, Inc. did not pay dividends during this period. Total return = price return.

Loading PRAX total return...

As of 2026-05-07

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	+18.00%	—	+18.00%	—	$11,800
1Y	+860.90%	860.90%	+860.90%	—	$96,090
3Y	+2005.61%	176.14%	+2005.61%	—	$210,561
5Y	-18.43%	-3.99%	-18.43%	—	$8,157
10Y	-18.96%	-2.08%	-18.96%	—	$8,104
15Y	-18.96%	-1.39%	-18.96%	—	$8,104
20Y	-18.96%	-1.05%	-18.96%	—	$8,104
30Y	-18.96%	-0.70%	-18.96%	—	$8,104

Risk & Highlights

Best Year+270.65%2025

Worst Year-88.27%2022

Max Drawdown-36.32%2025-07-25 → 2025-09-12 · Recovered 2025-10-16

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	+17.58%	+17.58%	—	+0.41%	+17.2pp
2025	+270.65%	+270.65%	—	+16.64%	+254.0pp
2024	+268.23%	+268.23%	—	+24.00%	+244.2pp
2023	-42.20%	-42.20%	—	+24.81%	-67.0pp
2022	-88.27%	-88.27%	—	-19.95%	-68.3pp

PRAX outperformed the S&P 500 by 829.58pp over the past year (+860.90% vs +31.32%).

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PRAX Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
PRAXPraxis Precision Medicines, Inc.	$7.6B	+9.0%	+18.0%	+860.9%	—	+2005.6%	-18.4%	-19.0%
ACADACADIA Pharmaceuticals Inc.	$3.7B	-3.8%	-17.9%	+47.7%	—	-0.3%	+2.5%	-22.3%
NRIXNurix Therapeutics, Inc.	$1.7B	+6.9%	-6.5%	+74.9%	—	+83.1%	-38.3%	-11.2%
ARVNArvinas, Inc.	$656M	-8.6%	-10.5%	+47.6%	—	-58.4%	-83.8%	-36.1%
LGNDLigand Pharmaceuticals Incorporated	$4.6B	+14.2%	+22.3%	+125.1%	—	+200.3%	+83.9%	+95.1%
OVIDOvid Therapeutics Inc.	$362M	+20.9%	+58.0%	+869.3%	—	-19.7%	-19.7%	-77.3%
PTCTPTC Therapeutics, Inc.	$5.5B	-3.3%	-13.2%	+84.1%	—	+19.9%	+65.2%	+839.5%
KALAKALA BIO, Inc.	$855,530	-33.4%	-81.5%	-96.7%	—	-99.3%	-100.0%	-100.0%
ENOVEnovis Corporation	$1.4B	+9.2%	-6.3%	-27.1%	—	-56.3%	-66.2%	-43.2%
ILMNIllumina, Inc.	$21.7B	+11.6%	+6.1%	+91.3%	—	-25.0%	-61.1%	+4.3%
PACBPacific Biosciences of California, Inc.	$516M	+20.4%	-7.1%	+55.5%	—	-86.0%	-93.0%	-80.3%

Compare:PRAX vs ACAD PRAX vs NRIX PRAX vs ARVN PRAX vs ACAD vs NRIX

About PRAX Dividend Returns

Praxis Precision Medicines, Inc. (PRAX) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of PRAX over the past year?

Praxis Precision Medicines, Inc. (PRAX) delivered a return of 860.90% over the past year. Since PRAX does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in PRAX be worth today?

A $10,000 investment in Praxis Precision Medicines, Inc. one year ago would be worth $96,090 today, representing a gain of $86,090.

Q3Does PRAX pay dividends?

Praxis Precision Medicines, Inc. (PRAX) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For PRAX, the total return equals the price-only return.

Q4Did PRAX beat the S&P 500?

Yes, Praxis Precision Medicines, Inc. (PRAX) outperformed the S&P 500 by 829.58 percentage points over the past year. PRAX delivered a total return of 860.90%, compared to the S&P 500's 31.32%. This 829.58pp alpha means investors in PRAX earned more than a passive S&P 500 index fund.

Q5What is PRAX's worst drawdown?

Praxis Precision Medicines, Inc. (PRAX) experienced a maximum drawdown of -36.32% over the past year, declining from its peak on 2025-07-25 to its trough on 2025-09-12. The stock recovered to its prior peak by 2025-10-16. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is PRAX's long-term total return over 10, 20, or 30 years?

Here are Praxis Precision Medicines, Inc. (PRAX)'s long-term returns with dividends reinvested. Over 10 years, the total return is -19.0% (-2.1% CAGR) — $10,000 would have grown to $8,104. Over 20 years: -19.0% total return (-1.0% CAGR) — $10,000 → $8,104. Over 30 years: -19.0% total return (-0.7% CAGR) — $10,000 → $8,104. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was PRAX's best and worst year?

Praxis Precision Medicines, Inc.'s best calendar year was 2025 with a total return of 270.6%. Its worst year was 2022 with a total return of -88.3%. This range shows the volatility investors should expect — the difference between the best and worst year is 358.9 percentage points.