Medical - Devices
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5 / 10Stock Comparison
IRTC vs ITGR vs INVA vs BDX vs HOLX
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Devices
Biotechnology
Medical - Instruments & Supplies
Medical - Instruments & Supplies
IRTC vs ITGR vs INVA vs BDX vs HOLX — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Devices | Medical - Devices | Biotechnology | Medical - Instruments & Supplies | Medical - Instruments & Supplies |
| Market Cap | $4.10B | $3.03B | $1.93B | $55.53B | $16.97B |
| Revenue (TTM) | $788M | $1.85B | $424M | $21.36B | $4.13B |
| Net Income (TTM) | $-28M | $142M | $504M | $1.14B | $544M |
| Gross Margin | 71.0% | 23.3% | 76.2% | 46.5% | 52.8% |
| Operating Margin | -3.3% | 10.4% | 14.8% | 10.6% | 17.5% |
| Forward P/E | — | 13.5x | 11.9x | 12.3x | 17.2x |
| Total Debt | $731M | $1.40B | $269M | $19.18B | $2.63B |
| Cash & Equiv. | $236M | $17M | $551M | $851M | $1.96B |
IRTC vs ITGR vs INVA vs BDX vs HOLX — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| iRhythm Technologie… (IRTC) | 100 | 100.5 | +0.5% |
| Integer Holdings Co… (ITGR) | 100 | 111.0 | +11.0% |
| Innoviva, Inc. (INVA) | 100 | 163.2 | +63.2% |
| Becton, Dickinson a… (BDX) | 100 | 103.0 | +3.0% |
| Hologic, Inc. (HOLX) | 100 | 142.6 | +42.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: IRTC vs ITGR vs INVA vs BDX vs HOLX
Each card shows where this stock fits in a portfolio — not just who wins on paper.
IRTC ranks third and is worth considering specifically for growth exposure and long-term compounding.
- Rev growth 26.2%, EPS growth 61.7%, 3Y rev CAGR 22.1%
- 379.3% 10Y total return vs INVA's 94.9%
- 26.2% revenue growth vs HOLX's 1.7%
ITGR lags the leaders in this set but could rank higher in a more targeted comparison.
INVA carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and defensive.
- Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
- Beta 0.13, current ratio 14.64x
- Lower P/E (11.9x vs 17.2x)
- 118.9% margin vs IRTC's -3.5%
BDX is the #2 pick in this set and the best alternative if income & stability and valuation efficiency is your priority.
- Dividend streak 1 yrs, beta 0.66, yield 2.7%
- PEG 0.74 vs ITGR's 3.08
- 2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend
- +51.8% vs ITGR's -26.1%
Among these 5 stocks, HOLX doesn't own a clear edge in any measured category.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 26.2% revenue growth vs HOLX's 1.7% | |
| Value | Lower P/E (11.9x vs 17.2x) | |
| Quality / Margins | 118.9% margin vs IRTC's -3.5% | |
| Stability / Safety | Beta 0.13 vs IRTC's 0.93, lower leverage | |
| Dividends | 2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +51.8% vs ITGR's -26.1% | |
| Efficiency (ROA) | 32.4% ROA vs IRTC's -2.8%, ROIC 14.2% vs -5.2% |
IRTC vs ITGR vs INVA vs BDX vs HOLX — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
IRTC vs ITGR vs INVA vs BDX vs HOLX — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
INVA leads in 4 of 6 categories
BDX leads 1 • IRTC leads 0 • ITGR leads 0 • HOLX leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
INVA leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BDX is the larger business by revenue, generating $21.4B annually — 50.4x INVA's $424M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to IRTC's -3.5%. On growth, IRTC holds the edge at +25.7% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $788M | $1.8B | $424M | $21.4B | $4.1B |
| EBITDAEarnings before interest/tax | -$6M | $328M | $86M | $4.2B | $974M |
| Net IncomeAfter-tax profit | -$28M | $142M | $504M | $1.1B | $544M |
| Free Cash FlowCash after capex | $19M | $168M | $181M | $3.1B | $1000M |
| Gross MarginGross profit ÷ Revenue | +71.0% | +23.3% | +76.2% | +46.5% | +52.8% |
| Operating MarginEBIT ÷ Revenue | -3.3% | +10.4% | +14.8% | +10.6% | +17.5% |
| Net MarginNet income ÷ Revenue | -3.5% | +7.7% | +118.9% | +5.3% | +13.2% |
| FCF MarginFCF ÷ Revenue | +2.4% | +9.1% | +42.8% | +14.7% | +24.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | +25.7% | +0.8% | +10.6% | -10.6% | +2.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +55.7% | +172.7% | +4.0% | -2.0% | -9.2% |
Valuation Metrics
INVA leads this category, winning 5 of 7 comparable metrics.
Valuation Metrics
At 6.9x trailing earnings, INVA trades at a 77% valuation discount to HOLX's 30.5x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs ITGR's 6.91x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $4.1B | $3.0B | $1.9B | $55.5B | $17.0B |
| Enterprise ValueMkt cap + debt − cash | $4.6B | $4.4B | $1.7B | $73.9B | $17.6B |
| Trailing P/EPrice ÷ TTM EPS | -89.83x | 30.42x | 6.91x | 26.29x | 30.53x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 13.55x | 11.91x | 12.27x | 17.21x |
| PEG RatioP/E ÷ EPS growth rate | — | 6.91x | 0.67x | 1.59x | — |
| EV / EBITDAEnterprise value multiple | — | 13.15x | 8.10x | 14.65x | 17.39x |
| Price / SalesMarket cap ÷ Revenue | 5.49x | 1.64x | 4.55x | 2.54x | 4.14x |
| Price / BookPrice ÷ Book value/share | 26.16x | 1.79x | 1.65x | 1.73x | 3.43x |
| Price / FCFMarket cap ÷ FCF | 118.84x | 28.78x | 9.88x | 20.80x | 18.44x |
Profitability & Efficiency
INVA leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-21 for IRTC. INVA carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to IRTC's 4.79x. On the Piotroski fundamental quality scale (0–9), BDX scores 7/9 vs INVA's 5/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -20.6% | +8.2% | +46.5% | +4.5% | +11.0% |
| ROA (TTM)Return on assets | -2.8% | +4.2% | +32.4% | +2.1% | +6.1% |
| ROICReturn on invested capital | -5.2% | +5.4% | +14.2% | +4.3% | +9.4% |
| ROCEReturn on capital employed | -4.4% | +6.9% | +12.4% | +5.4% | +8.8% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 5 | 5 | 7 | 7 |
| Debt / EquityFinancial leverage | 4.79x | 0.80x | 0.23x | 0.76x | 0.52x |
| Net DebtTotal debt minus cash | $495M | $1.4B | -$282M | $18.3B | $667M |
| Cash & Equiv.Liquid assets | $236M | $17M | $551M | $851M | $2.0B |
| Total DebtShort + long-term debt | $731M | $1.4B | $269M | $19.2B | $2.6B |
| Interest CoverageEBIT ÷ Interest expense | -1.48x | 5.07x | 63.45x | 4.09x | 8.00x |
Total Returns (Dividends Reinvested)
INVA leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $9,252 for ITGR. Over the past 12 months, BDX leads with a +51.8% total return vs ITGR's -26.1%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.0% vs HOLX's -2.9% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -28.7% | +14.5% | +14.7% | +0.7% | +1.9% |
| 1-Year ReturnPast 12 months | -8.3% | -26.1% | +21.7% | +51.8% | +37.1% |
| 3-Year ReturnCumulative with dividends | -2.1% | +8.8% | +95.2% | +5.0% | -8.5% |
| 5-Year ReturnCumulative with dividends | +56.1% | -7.5% | +94.4% | +16.9% | +15.8% |
| 10-Year ReturnCumulative with dividends | +379.3% | +165.1% | +94.9% | +80.2% | +124.3% |
| CAGR (3Y)Annualised 3-year return | -0.7% | +2.9% | +25.0% | +1.6% | -2.9% |
Risk & Volatility
Evenly matched — INVA and HOLX each lead in 1 of 2 comparable metrics.
Risk & Volatility
INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than IRTC's 0.93 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs IRTC's 58.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.93x | 0.72x | 0.13x | 0.66x | 0.41x |
| 52-Week HighHighest price in past year | $212.00 | $123.78 | $25.15 | $205.52 | $76.04 |
| 52-Week LowLowest price in past year | $112.31 | $62.00 | $16.52 | $100.31 | $52.81 |
| % of 52W HighCurrent price vs 52-week peak | +58.9% | +71.0% | +90.7% | +74.6% | +100.0% |
| RSI (14)Momentum oscillator 0–100 | 44.1 | 50.9 | 39.9 | 32.2 | 69.1 |
| Avg Volume (50D)Average daily shares traded | 524K | 628K | 621K | 2.5M | 10.0M |
Analyst Outlook
BDX leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: IRTC as "Buy", ITGR as "Buy", INVA as "Buy", BDX as "Buy", HOLX as "Hold". Consensus price targets imply 65.2% upside for INVA (target: $38) vs 3.9% for HOLX (target: $79). BDX is the only dividend payer here at 2.72% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | $193.67 | $98.00 | $37.67 | $172.85 | $79.00 |
| # AnalystsCovering analysts | 19 | 14 | 10 | 33 | 42 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +2.7% | — |
| Dividend StreakConsecutive years of raises | — | — | 0 | 1 | — |
| Dividend / ShareAnnual DPS | — | — | — | $4.17 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +1.7% | +0.2% | +1.8% | +4.4% |
INVA leads in 4 of 6 categories (Income & Cash Flow, Valuation Metrics). BDX leads in 1 (Analyst Outlook). 1 tied.
IRTC vs ITGR vs INVA vs BDX vs HOLX: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is IRTC or ITGR or INVA or BDX or HOLX a better buy right now?
For growth investors, iRhythm Technologies, Inc.
(IRTC) is the stronger pick with 26. 2% revenue growth year-over-year, versus 1. 7% for Hologic, Inc. (HOLX). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (11. 9x forward), making it the more compelling value choice. Analysts rate iRhythm Technologies, Inc. (IRTC) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — IRTC or ITGR or INVA or BDX or HOLX?
On trailing P/E, Innoviva, Inc.
(INVA) is the cheapest at 6. 9x versus Hologic, Inc. at 30. 5x. On forward P/E, Innoviva, Inc. is actually cheaper at 11. 9x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Becton, Dickinson and Company wins at 0. 74x versus Integer Holdings Corporation's 3. 08x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — IRTC or ITGR or INVA or BDX or HOLX?
Over the past 5 years, Innoviva, Inc.
(INVA) delivered a total return of +94. 4%, compared to -7. 5% for Integer Holdings Corporation (ITGR). Over 10 years, the gap is even starker: IRTC returned +379. 3% versus BDX's +80. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — IRTC or ITGR or INVA or BDX or HOLX?
By beta (market sensitivity over 5 years), Innoviva, Inc.
(INVA) is the lower-risk stock at 0. 13β versus iRhythm Technologies, Inc. 's 0. 93β — meaning IRTC is approximately 639% more volatile than INVA relative to the S&P 500. On balance sheet safety, Innoviva, Inc. (INVA) carries a lower debt/equity ratio of 23% versus 5% for iRhythm Technologies, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — IRTC or ITGR or INVA or BDX or HOLX?
By revenue growth (latest reported year), iRhythm Technologies, Inc.
(IRTC) is pulling ahead at 26. 2% versus 1. 7% for Hologic, Inc. (HOLX). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -25. 0% for Hologic, Inc.. Over a 3-year CAGR, IRTC leads at 22. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — IRTC or ITGR or INVA or BDX or HOLX?
Innoviva, Inc.
(INVA) is the more profitable company, earning 63. 8% net margin versus -6. 0% for iRhythm Technologies, Inc. — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -4. 9% for IRTC. At the gross margin level — before operating expenses — INVA leads at 72. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is IRTC or ITGR or INVA or BDX or HOLX more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Becton, Dickinson and Company (BDX) is the more undervalued stock at a PEG of 0. 74x versus Integer Holdings Corporation's 3. 08x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Innoviva, Inc. (INVA) trades at 11. 9x forward P/E versus 17. 2x for Hologic, Inc. — 5. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for INVA: 65. 2% to $37. 67.
08Which pays a better dividend — IRTC or ITGR or INVA or BDX or HOLX?
In this comparison, BDX (2.
7% yield) pays a dividend. IRTC, ITGR, INVA, HOLX do not pay a meaningful dividend and should not be held primarily for income.
09Is IRTC or ITGR or INVA or BDX or HOLX better for a retirement portfolio?
For long-horizon retirement investors, Becton, Dickinson and Company (BDX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
66), 2. 7% yield). Both have compounded well over 10 years (BDX: +80. 2%, IRTC: +379. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between IRTC and ITGR and INVA and BDX and HOLX?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: IRTC is a small-cap high-growth stock; ITGR is a small-cap quality compounder stock; INVA is a small-cap high-growth stock; BDX is a mid-cap quality compounder stock; HOLX is a mid-cap quality compounder stock. BDX pays a dividend while IRTC, ITGR, INVA, HOLX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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