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IRTC vs ITGR vs INVA vs BDX vs HOLX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
IRTC
iRhythm Technologies, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$4.10B
5Y Perf.+0.5%
ITGR
Integer Holdings Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$3.03B
5Y Perf.+11.0%
INVA
Innoviva, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.93B
5Y Perf.+63.2%
BDX
Becton, Dickinson and Company

Medical - Instruments & Supplies

HealthcareNYSE • US
Market Cap$55.53B
5Y Perf.+3.0%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+42.6%

IRTC vs ITGR vs INVA vs BDX vs HOLX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
IRTC logoIRTC
ITGR logoITGR
INVA logoINVA
BDX logoBDX
HOLX logoHOLX
IndustryMedical - DevicesMedical - DevicesBiotechnologyMedical - Instruments & SuppliesMedical - Instruments & Supplies
Market Cap$4.10B$3.03B$1.93B$55.53B$16.97B
Revenue (TTM)$788M$1.85B$424M$21.36B$4.13B
Net Income (TTM)$-28M$142M$504M$1.14B$544M
Gross Margin71.0%23.3%76.2%46.5%52.8%
Operating Margin-3.3%10.4%14.8%10.6%17.5%
Forward P/E13.5x11.9x12.3x17.2x
Total Debt$731M$1.40B$269M$19.18B$2.63B
Cash & Equiv.$236M$17M$551M$851M$1.96B

IRTC vs ITGR vs INVA vs BDX vs HOLXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

IRTC
ITGR
INVA
BDX
HOLX
StockMay 20May 26Return
iRhythm Technologie… (IRTC)100100.5+0.5%
Integer Holdings Co… (ITGR)100111.0+11.0%
Innoviva, Inc. (INVA)100163.2+63.2%
Becton, Dickinson a… (BDX)100103.0+3.0%
Hologic, Inc. (HOLX)100142.6+42.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: IRTC vs ITGR vs INVA vs BDX vs HOLX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INVA leads in 4 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Becton, Dickinson and Company is the stronger pick specifically for dividend income and shareholder returns and recent price momentum and sentiment. IRTC also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
IRTC
iRhythm Technologies, Inc.
The Growth Play

IRTC ranks third and is worth considering specifically for growth exposure and long-term compounding.

  • Rev growth 26.2%, EPS growth 61.7%, 3Y rev CAGR 22.1%
  • 379.3% 10Y total return vs INVA's 94.9%
  • 26.2% revenue growth vs HOLX's 1.7%
Best for: growth exposure and long-term compounding
ITGR
Integer Holdings Corporation
The Lower-Volatility Pick

ITGR lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
INVA
Innoviva, Inc.
The Defensive Pick

INVA carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and defensive.

  • Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
  • Beta 0.13, current ratio 14.64x
  • Lower P/E (11.9x vs 17.2x)
  • 118.9% margin vs IRTC's -3.5%
Best for: sleep-well-at-night and defensive
BDX
Becton, Dickinson and Company
The Income Pick

BDX is the #2 pick in this set and the best alternative if income & stability and valuation efficiency is your priority.

  • Dividend streak 1 yrs, beta 0.66, yield 2.7%
  • PEG 0.74 vs ITGR's 3.08
  • 2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend
  • +51.8% vs ITGR's -26.1%
Best for: income & stability and valuation efficiency
HOLX
Hologic, Inc.
The Lower-Volatility Pick

Among these 5 stocks, HOLX doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthIRTC logoIRTC26.2% revenue growth vs HOLX's 1.7%
ValueINVA logoINVALower P/E (11.9x vs 17.2x)
Quality / MarginsINVA logoINVA118.9% margin vs IRTC's -3.5%
Stability / SafetyINVA logoINVABeta 0.13 vs IRTC's 0.93, lower leverage
DividendsBDX logoBDX2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)BDX logoBDX+51.8% vs ITGR's -26.1%
Efficiency (ROA)INVA logoINVA32.4% ROA vs IRTC's -2.8%, ROIC 14.2% vs -5.2%

IRTC vs ITGR vs INVA vs BDX vs HOLX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

IRTCiRhythm Technologies, Inc.
FY 2025
Commercial Payors
52.5%$392M
Centers For Medicare And Medicaid
24.0%$179M
Healthcare Institutions
16.8%$126M
Non-contracted Third-party Payors
6.7%$50M
ITGRInteger Holdings Corporation
FY 2025
Cardio And Vascular
59.7%$1.1B
Cardiac Rhythm Management & Neuromodulation
36.1%$669M
Other Markets
4.2%$78M
INVAInnoviva, Inc.
FY 2025
Royalty
57.5%$236M
Product
41.8%$172M
License And Other Revenue
0.7%$3M
BDXBecton, Dickinson and Company
FY 2025
Medical
52.5%$11.5B
Interventional
23.9%$5.2B
Life Sciences
23.7%$5.2B
HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M

IRTC vs ITGR vs INVA vs BDX vs HOLX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLINVALAGGINGHOLX

Income & Cash Flow (Last 12 Months)

INVA leads this category, winning 4 of 6 comparable metrics.

BDX is the larger business by revenue, generating $21.4B annually — 50.4x INVA's $424M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to IRTC's -3.5%. On growth, IRTC holds the edge at +25.7% YoY revenue growth, suggesting stronger near-term business momentum.

MetricIRTC logoIRTCiRhythm Technolog…ITGR logoITGRInteger Holdings …INVA logoINVAInnoviva, Inc.BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.
RevenueTrailing 12 months$788M$1.8B$424M$21.4B$4.1B
EBITDAEarnings before interest/tax-$6M$328M$86M$4.2B$974M
Net IncomeAfter-tax profit-$28M$142M$504M$1.1B$544M
Free Cash FlowCash after capex$19M$168M$181M$3.1B$1000M
Gross MarginGross profit ÷ Revenue+71.0%+23.3%+76.2%+46.5%+52.8%
Operating MarginEBIT ÷ Revenue-3.3%+10.4%+14.8%+10.6%+17.5%
Net MarginNet income ÷ Revenue-3.5%+7.7%+118.9%+5.3%+13.2%
FCF MarginFCF ÷ Revenue+2.4%+9.1%+42.8%+14.7%+24.2%
Rev. Growth (YoY)Latest quarter vs prior year+25.7%+0.8%+10.6%-10.6%+2.5%
EPS Growth (YoY)Latest quarter vs prior year+55.7%+172.7%+4.0%-2.0%-9.2%
INVA leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

INVA leads this category, winning 5 of 7 comparable metrics.

At 6.9x trailing earnings, INVA trades at a 77% valuation discount to HOLX's 30.5x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs ITGR's 6.91x — a lower PEG means you pay less per unit of expected earnings growth.

MetricIRTC logoIRTCiRhythm Technolog…ITGR logoITGRInteger Holdings …INVA logoINVAInnoviva, Inc.BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.
Market CapShares × price$4.1B$3.0B$1.9B$55.5B$17.0B
Enterprise ValueMkt cap + debt − cash$4.6B$4.4B$1.7B$73.9B$17.6B
Trailing P/EPrice ÷ TTM EPS-89.83x30.42x6.91x26.29x30.53x
Forward P/EPrice ÷ next-FY EPS est.13.55x11.91x12.27x17.21x
PEG RatioP/E ÷ EPS growth rate6.91x0.67x1.59x
EV / EBITDAEnterprise value multiple13.15x8.10x14.65x17.39x
Price / SalesMarket cap ÷ Revenue5.49x1.64x4.55x2.54x4.14x
Price / BookPrice ÷ Book value/share26.16x1.79x1.65x1.73x3.43x
Price / FCFMarket cap ÷ FCF118.84x28.78x9.88x20.80x18.44x
INVA leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

INVA leads this category, winning 8 of 9 comparable metrics.

INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-21 for IRTC. INVA carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to IRTC's 4.79x. On the Piotroski fundamental quality scale (0–9), BDX scores 7/9 vs INVA's 5/9, reflecting strong financial health.

MetricIRTC logoIRTCiRhythm Technolog…ITGR logoITGRInteger Holdings …INVA logoINVAInnoviva, Inc.BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.
ROE (TTM)Return on equity-20.6%+8.2%+46.5%+4.5%+11.0%
ROA (TTM)Return on assets-2.8%+4.2%+32.4%+2.1%+6.1%
ROICReturn on invested capital-5.2%+5.4%+14.2%+4.3%+9.4%
ROCEReturn on capital employed-4.4%+6.9%+12.4%+5.4%+8.8%
Piotroski ScoreFundamental quality 0–965577
Debt / EquityFinancial leverage4.79x0.80x0.23x0.76x0.52x
Net DebtTotal debt minus cash$495M$1.4B-$282M$18.3B$667M
Cash & Equiv.Liquid assets$236M$17M$551M$851M$2.0B
Total DebtShort + long-term debt$731M$1.4B$269M$19.2B$2.6B
Interest CoverageEBIT ÷ Interest expense-1.48x5.07x63.45x4.09x8.00x
INVA leads this category, winning 8 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

INVA leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $9,252 for ITGR. Over the past 12 months, BDX leads with a +51.8% total return vs ITGR's -26.1%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.0% vs HOLX's -2.9% — a key indicator of consistent wealth creation.

MetricIRTC logoIRTCiRhythm Technolog…ITGR logoITGRInteger Holdings …INVA logoINVAInnoviva, Inc.BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.
YTD ReturnYear-to-date-28.7%+14.5%+14.7%+0.7%+1.9%
1-Year ReturnPast 12 months-8.3%-26.1%+21.7%+51.8%+37.1%
3-Year ReturnCumulative with dividends-2.1%+8.8%+95.2%+5.0%-8.5%
5-Year ReturnCumulative with dividends+56.1%-7.5%+94.4%+16.9%+15.8%
10-Year ReturnCumulative with dividends+379.3%+165.1%+94.9%+80.2%+124.3%
CAGR (3Y)Annualised 3-year return-0.7%+2.9%+25.0%+1.6%-2.9%
INVA leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — INVA and HOLX each lead in 1 of 2 comparable metrics.

INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than IRTC's 0.93 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs IRTC's 58.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricIRTC logoIRTCiRhythm Technolog…ITGR logoITGRInteger Holdings …INVA logoINVAInnoviva, Inc.BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.
Beta (5Y)Sensitivity to S&P 5000.93x0.72x0.13x0.66x0.41x
52-Week HighHighest price in past year$212.00$123.78$25.15$205.52$76.04
52-Week LowLowest price in past year$112.31$62.00$16.52$100.31$52.81
% of 52W HighCurrent price vs 52-week peak+58.9%+71.0%+90.7%+74.6%+100.0%
RSI (14)Momentum oscillator 0–10044.150.939.932.269.1
Avg Volume (50D)Average daily shares traded524K628K621K2.5M10.0M
Evenly matched — INVA and HOLX each lead in 1 of 2 comparable metrics.

Analyst Outlook

BDX leads this category, winning 1 of 1 comparable metric.

Analyst consensus: IRTC as "Buy", ITGR as "Buy", INVA as "Buy", BDX as "Buy", HOLX as "Hold". Consensus price targets imply 65.2% upside for INVA (target: $38) vs 3.9% for HOLX (target: $79). BDX is the only dividend payer here at 2.72% yield — a key consideration for income-focused portfolios.

MetricIRTC logoIRTCiRhythm Technolog…ITGR logoITGRInteger Holdings …INVA logoINVAInnoviva, Inc.BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyHold
Price TargetConsensus 12-month target$193.67$98.00$37.67$172.85$79.00
# AnalystsCovering analysts1914103342
Dividend YieldAnnual dividend ÷ price+2.7%
Dividend StreakConsecutive years of raises01
Dividend / ShareAnnual DPS$4.17
Buyback YieldShare repurchases ÷ mkt cap0.0%+1.7%+0.2%+1.8%+4.4%
BDX leads this category, winning 1 of 1 comparable metric.
Key Takeaway

INVA leads in 4 of 6 categories (Income & Cash Flow, Valuation Metrics). BDX leads in 1 (Analyst Outlook). 1 tied.

Best OverallInnoviva, Inc. (INVA)Leads 4 of 6 categories
Loading custom metrics...

IRTC vs ITGR vs INVA vs BDX vs HOLX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is IRTC or ITGR or INVA or BDX or HOLX a better buy right now?

For growth investors, iRhythm Technologies, Inc.

(IRTC) is the stronger pick with 26. 2% revenue growth year-over-year, versus 1. 7% for Hologic, Inc. (HOLX). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (11. 9x forward), making it the more compelling value choice. Analysts rate iRhythm Technologies, Inc. (IRTC) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — IRTC or ITGR or INVA or BDX or HOLX?

On trailing P/E, Innoviva, Inc.

(INVA) is the cheapest at 6. 9x versus Hologic, Inc. at 30. 5x. On forward P/E, Innoviva, Inc. is actually cheaper at 11. 9x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Becton, Dickinson and Company wins at 0. 74x versus Integer Holdings Corporation's 3. 08x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — IRTC or ITGR or INVA or BDX or HOLX?

Over the past 5 years, Innoviva, Inc.

(INVA) delivered a total return of +94. 4%, compared to -7. 5% for Integer Holdings Corporation (ITGR). Over 10 years, the gap is even starker: IRTC returned +379. 3% versus BDX's +80. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — IRTC or ITGR or INVA or BDX or HOLX?

By beta (market sensitivity over 5 years), Innoviva, Inc.

(INVA) is the lower-risk stock at 0. 13β versus iRhythm Technologies, Inc. 's 0. 93β — meaning IRTC is approximately 639% more volatile than INVA relative to the S&P 500. On balance sheet safety, Innoviva, Inc. (INVA) carries a lower debt/equity ratio of 23% versus 5% for iRhythm Technologies, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — IRTC or ITGR or INVA or BDX or HOLX?

By revenue growth (latest reported year), iRhythm Technologies, Inc.

(IRTC) is pulling ahead at 26. 2% versus 1. 7% for Hologic, Inc. (HOLX). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -25. 0% for Hologic, Inc.. Over a 3-year CAGR, IRTC leads at 22. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — IRTC or ITGR or INVA or BDX or HOLX?

Innoviva, Inc.

(INVA) is the more profitable company, earning 63. 8% net margin versus -6. 0% for iRhythm Technologies, Inc. — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -4. 9% for IRTC. At the gross margin level — before operating expenses — INVA leads at 72. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is IRTC or ITGR or INVA or BDX or HOLX more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Becton, Dickinson and Company (BDX) is the more undervalued stock at a PEG of 0. 74x versus Integer Holdings Corporation's 3. 08x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Innoviva, Inc. (INVA) trades at 11. 9x forward P/E versus 17. 2x for Hologic, Inc. — 5. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for INVA: 65. 2% to $37. 67.

08

Which pays a better dividend — IRTC or ITGR or INVA or BDX or HOLX?

In this comparison, BDX (2.

7% yield) pays a dividend. IRTC, ITGR, INVA, HOLX do not pay a meaningful dividend and should not be held primarily for income.

09

Is IRTC or ITGR or INVA or BDX or HOLX better for a retirement portfolio?

For long-horizon retirement investors, Becton, Dickinson and Company (BDX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

66), 2. 7% yield). Both have compounded well over 10 years (BDX: +80. 2%, IRTC: +379. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between IRTC and ITGR and INVA and BDX and HOLX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: IRTC is a small-cap high-growth stock; ITGR is a small-cap quality compounder stock; INVA is a small-cap high-growth stock; BDX is a mid-cap quality compounder stock; HOLX is a mid-cap quality compounder stock. BDX pays a dividend while IRTC, ITGR, INVA, HOLX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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