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4 / 10Stock Comparison
ITGR vs DBVT vs ALKS vs NVCR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Instruments & Supplies
ITGR vs DBVT vs ALKS vs NVCR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Devices | Biotechnology | Biotechnology | Medical - Instruments & Supplies |
| Market Cap | $3.03B | $1712.35T | $5.90B | $1.92B |
| Revenue (TTM) | $1.85B | $0.00 | $1.56B | $674M |
| Net Income (TTM) | $142M | $-168M | $153M | $-173M |
| Gross Margin | 23.3% | — | 65.4% | 75.2% |
| Operating Margin | 10.4% | — | 12.3% | -27.2% |
| Forward P/E | 13.5x | — | 24.8x | — |
| Total Debt | $1.40B | $22M | $70M | $290M |
| Cash & Equiv. | $17M | $194M | $1.12B | $103M |
ITGR vs DBVT vs ALKS vs NVCR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Integer Holdings Co… (ITGR) | 100 | 111.0 | +11.0% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Alkermes plc (ALKS) | 100 | 216.4 | +116.4% |
| NovoCure Limited (NVCR) | 100 | 25.0 | -75.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ITGR vs DBVT vs ALKS vs NVCR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ITGR has the current edge in this matchup, primarily because of its strength in long-term compounding and defensive.
- 165.1% 10Y total return vs ALKS's -11.0%
- Beta 0.72, current ratio 3.32x
- Better valuation composite
- Beta 0.72 vs NVCR's 2.20, lower leverage
DBVT is the clearest fit if your priority is income & stability.
- Dividend streak 0 yrs, beta 1.26
- +110.4% vs ITGR's -26.1%
ALKS is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.
- Lower volatility, beta 1.06, Low D/E 3.8%, current ratio 3.55x
- 9.8% margin vs NVCR's -25.7%
- 5.4% ROA vs DBVT's -89.0%
NVCR is the clearest fit if your priority is growth exposure.
- Rev growth 8.3%, EPS growth 21.8%, 3Y rev CAGR 6.8%
- 8.3% revenue growth vs DBVT's -100.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.3% revenue growth vs DBVT's -100.0% | |
| Value | Better valuation composite | |
| Quality / Margins | 9.8% margin vs NVCR's -25.7% | |
| Stability / Safety | Beta 0.72 vs NVCR's 2.20, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +110.4% vs ITGR's -26.1% | |
| Efficiency (ROA) | 5.4% ROA vs DBVT's -89.0% |
ITGR vs DBVT vs ALKS vs NVCR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
ITGR vs DBVT vs ALKS vs NVCR — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ALKS leads in 2 of 6 categories
ITGR leads 1 • DBVT leads 1 • NVCR leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ALKS leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ITGR and DBVT operate at a comparable scale, with $1.8B and $0 in trailing revenue. ALKS is the more profitable business, keeping 9.8% of every revenue dollar as net income compared to NVCR's -25.7%. On growth, ALKS holds the edge at +28.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $1.8B | $0 | $1.6B | $674M |
| EBITDAEarnings before interest/tax | $328M | -$112M | $212M | -$165M |
| Net IncomeAfter-tax profit | $142M | -$168M | $153M | -$173M |
| Free Cash FlowCash after capex | $168M | -$151M | $392M | -$48M |
| Gross MarginGross profit ÷ Revenue | +23.3% | — | +65.4% | +75.2% |
| Operating MarginEBIT ÷ Revenue | +10.4% | — | +12.3% | -27.2% |
| Net MarginNet income ÷ Revenue | +7.7% | — | +9.8% | -25.7% |
| FCF MarginFCF ÷ Revenue | +9.1% | — | +25.1% | -7.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +0.8% | — | +28.2% | +12.3% |
| EPS Growth (YoY)Latest quarter vs prior year | +172.7% | +91.5% | -4.1% | -100.0% |
Valuation Metrics
ITGR leads this category, winning 2 of 5 comparable metrics.
Valuation Metrics
At 24.8x trailing earnings, ALKS trades at a 19% valuation discount to ITGR's 30.4x P/E. On an enterprise value basis, ITGR's 13.1x EV/EBITDA is more attractive than ALKS's 17.3x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $3.0B | $1712.35T | $5.9B | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $4.4B | $1712.35T | $4.9B | $2.1B |
| Trailing P/EPrice ÷ TTM EPS | 30.42x | -0.76x | 24.76x | -13.80x |
| Forward P/EPrice ÷ next-FY EPS est. | 13.55x | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | 6.91x | — | — | — |
| EV / EBITDAEnterprise value multiple | 13.15x | — | 17.25x | — |
| Price / SalesMarket cap ÷ Revenue | 1.64x | — | 4.00x | 2.92x |
| Price / BookPrice ÷ Book value/share | 1.79x | 0.66x | 3.28x | 5.51x |
| Price / FCFMarket cap ÷ FCF | 28.78x | — | 12.28x | — |
Profitability & Efficiency
ALKS leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
ALKS delivers a 8.8% return on equity — every $100 of shareholder capital generates $9 in annual profit, vs $-130 for DBVT. ALKS carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs DBVT's 4/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | +8.2% | -130.2% | +8.8% | -50.8% |
| ROA (TTM)Return on assets | +4.2% | -89.0% | +5.4% | -16.5% |
| ROICReturn on invested capital | +5.4% | — | +18.9% | -16.4% |
| ROCEReturn on capital employed | +6.9% | -145.7% | +14.2% | -28.9% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 7 | 5 |
| Debt / EquityFinancial leverage | 0.80x | 0.13x | 0.04x | 0.85x |
| Net DebtTotal debt minus cash | $1.4B | -$172M | -$1.0B | $187M |
| Cash & Equiv.Liquid assets | $17M | $194M | $1.1B | $103M |
| Total DebtShort + long-term debt | $1.4B | $22M | $70M | $290M |
| Interest CoverageEBIT ÷ Interest expense | 5.07x | -189.82x | 32.30x | -96.80x |
Total Returns (Dividends Reinvested)
DBVT leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ALKS five years ago would be worth $16,091 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, DBVT leads with a +110.4% total return vs ITGR's -26.1%. The 3-year compound annual growth rate (CAGR) favors DBVT at 6.2% vs NVCR's -37.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +14.5% | +4.9% | +25.3% | +28.3% |
| 1-Year ReturnPast 12 months | -26.1% | +110.4% | +16.5% | +1.1% |
| 3-Year ReturnCumulative with dividends | +8.8% | +19.7% | +14.5% | -75.7% |
| 5-Year ReturnCumulative with dividends | -7.5% | -69.1% | +60.9% | -91.3% |
| 10-Year ReturnCumulative with dividends | +165.1% | -87.0% | -11.0% | +30.3% |
| CAGR (3Y)Annualised 3-year return | +2.9% | +6.2% | +4.6% | -37.6% |
Risk & Volatility
Evenly matched — ITGR and ALKS each lead in 1 of 2 comparable metrics.
Risk & Volatility
ITGR is the less volatile stock with a 0.72 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 96.7% from its 52-week high vs ITGR's 71.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.72x | 1.26x | 1.06x | 2.20x |
| 52-Week HighHighest price in past year | $123.78 | $26.18 | $36.60 | $20.06 |
| 52-Week LowLowest price in past year | $62.00 | $7.53 | $25.17 | $9.82 |
| % of 52W HighCurrent price vs 52-week peak | +71.0% | +76.3% | +96.7% | +83.9% |
| RSI (14)Momentum oscillator 0–100 | 50.9 | 48.1 | 60.2 | 69.8 |
| Avg Volume (50D)Average daily shares traded | 628K | 252K | 2.3M | 1.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ITGR as "Buy", DBVT as "Buy", ALKS as "Buy", NVCR as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 11.5% for ITGR (target: $98).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $98.00 | $46.33 | $44.00 | $33.50 |
| # AnalystsCovering analysts | 14 | 15 | 28 | 15 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | 0 | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +1.7% | 0.0% | +0.5% | 0.0% |
ALKS leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ITGR leads in 1 (Valuation Metrics). 1 tied.
ITGR vs DBVT vs ALKS vs NVCR: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ITGR or DBVT or ALKS or NVCR a better buy right now?
For growth investors, NovoCure Limited (NVCR) is the stronger pick with 8.
3% revenue growth year-over-year, versus -5. 2% for Alkermes plc (ALKS). Alkermes plc (ALKS) offers the better valuation at 24. 8x trailing P/E, making it the more compelling value choice. Analysts rate Integer Holdings Corporation (ITGR) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ITGR or DBVT or ALKS or NVCR?
On trailing P/E, Alkermes plc (ALKS) is the cheapest at 24.
8x versus Integer Holdings Corporation at 30. 4x.
03Which is the better long-term investment — ITGR or DBVT or ALKS or NVCR?
Over the past 5 years, Alkermes plc (ALKS) delivered a total return of +60.
9%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: ITGR returned +165. 1% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ITGR or DBVT or ALKS or NVCR?
By beta (market sensitivity over 5 years), Integer Holdings Corporation (ITGR) is the lower-risk stock at 0.
72β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 206% more volatile than ITGR relative to the S&P 500. On balance sheet safety, Alkermes plc (ALKS) carries a lower debt/equity ratio of 4% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.
05Which is growing faster — ITGR or DBVT or ALKS or NVCR?
By revenue growth (latest reported year), NovoCure Limited (NVCR) is pulling ahead at 8.
3% versus -5. 2% for Alkermes plc (ALKS). On earnings-per-share growth, the picture is similar: NovoCure Limited grew EPS 21. 8% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, ITGR leads at 11. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ITGR or DBVT or ALKS or NVCR?
Alkermes plc (ALKS) is the more profitable company, earning 16.
4% net margin versus -20. 8% for NovoCure Limited — meaning it keeps 16. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ALKS leads at 17. 2% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — ALKS leads at 86. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ITGR or DBVT or ALKS or NVCR more undervalued right now?
Analyst consensus price targets imply the most upside for DBVT: 131.
8% to $46. 33.
08Which pays a better dividend — ITGR or DBVT or ALKS or NVCR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is ITGR or DBVT or ALKS or NVCR better for a retirement portfolio?
For long-horizon retirement investors, Integer Holdings Corporation (ITGR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
72), +165. 1% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 20 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ITGR: +165. 1%, NVCR: +30. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ITGR and DBVT and ALKS and NVCR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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