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KPRX vs RCKT vs CRSP vs EDIT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
KPRX vs RCKT vs CRSP vs EDIT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $8M | $398M | $5.06B | $297M |
| Revenue (TTM) | $0.00 | $0.00 | $4M | $0.00 |
| Net Income (TTM) | $-9M | $-223M | $-569M | $-160M |
| Gross Margin | 100.0% | — | -41.7% | — |
| Operating Margin | 28.2% | — | -134.1% | — |
| Forward P/E | 2.8x | — | — | — |
| Total Debt | $57K | $25M | $395M | $18M |
| Cash & Equiv. | $4M | $78M | $355M | $147M |
KPRX vs RCKT vs CRSP vs EDIT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Kiora Pharmaceutica… (KPRX) | 100 | 0.1 | -99.9% |
| Rocket Pharmaceutic… (RCKT) | 100 | 19.3 | -80.7% |
| CRISPR Therapeutics… (CRSP) | 100 | 84.9 | -15.1% |
| Editas Medicine, In… (EDIT) | 100 | 11.5 | -88.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: KPRX vs RCKT vs CRSP vs EDIT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
KPRX carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.29
- Rev growth -100.0%, EPS growth 103.6%
- Lower volatility, beta 1.29, Low D/E 0.2%, current ratio 4.94x
- Beta 1.29, current ratio 4.94x
RCKT is the #2 pick in this set and the best alternative if growth is your priority.
- 10.5% revenue growth vs EDIT's -100.0%
CRSP is the clearest fit if your priority is long-term compounding.
- 272.0% 10Y total return vs EDIT's -90.0%
- -24.5% ROA vs EDIT's -74.2%
EDIT is the clearest fit if your priority is momentum.
- +127.8% vs RCKT's -45.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 10.5% revenue growth vs EDIT's -100.0% | |
| Quality / Margins | 22.5% margin vs CRSP's -138.6% | |
| Stability / Safety | Beta 1.29 vs EDIT's 2.52, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +127.8% vs RCKT's -45.2% | |
| Efficiency (ROA) | -24.5% ROA vs EDIT's -74.2% |
KPRX vs RCKT vs CRSP vs EDIT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
KPRX vs RCKT vs CRSP vs EDIT — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
KPRX leads in 3 of 6 categories
CRSP leads 1 • RCKT leads 0 • EDIT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
KPRX leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
CRSP and EDIT operate at a comparable scale, with $4M and $0 in trailing revenue. KPRX is the more profitable business, keeping 22.5% of every revenue dollar as net income compared to CRSP's -138.6%. On growth, CRSP holds the edge at +68.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $4M | $0 |
| EBITDAEarnings before interest/tax | -$8M | -$232M | -$535M | $0 |
| Net IncomeAfter-tax profit | -$9M | -$223M | -$569M | -$160M |
| Free Cash FlowCash after capex | -$10M | -$190M | -$401M | -$166M |
| Gross MarginGross profit ÷ Revenue | +100.0% | — | -41.7% | — |
| Operating MarginEBIT ÷ Revenue | +28.2% | — | -134.1% | — |
| Net MarginNet income ÷ Revenue | +22.5% | — | -138.6% | — |
| FCF MarginFCF ÷ Revenue | +53.5% | — | -97.8% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +68.6% | -151.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +100.8% | +38.7% | +19.0% | +105.5% |
Valuation Metrics
KPRX leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $8M | $398M | $5.1B | $297M |
| Enterprise ValueMkt cap + debt − cash | $5M | $345M | $5.1B | $168M |
| Trailing P/EPrice ÷ TTM EPS | 2.82x | -1.83x | -8.10x | -1.68x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | 1.03x | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 0.53x | — | 1440.41x | — |
| Price / BookPrice ÷ Book value/share | 0.39x | 1.47x | 2.45x | 9.85x |
| Price / FCFMarket cap ÷ FCF | 0.98x | — | — | — |
Profitability & Efficiency
KPRX leads this category, winning 5 of 8 comparable metrics.
Profitability & Efficiency
CRSP delivers a -30.9% return on equity — every $100 of shareholder capital generates $-31 in annual profit, vs $-5 for EDIT. KPRX carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 0.66x. On the Piotroski fundamental quality scale (0–9), KPRX scores 8/9 vs EDIT's 1/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -36.4% | -80.5% | -30.9% | -5.2% |
| ROA (TTM)Return on assets | -25.8% | -67.5% | -24.5% | -74.2% |
| ROICReturn on invested capital | +26.2% | -63.2% | -22.3% | — |
| ROCEReturn on capital employed | +21.2% | -58.9% | -26.6% | — |
| Piotroski ScoreFundamental quality 0–9 | 8 | 1 | 1 | 1 |
| Debt / EquityFinancial leverage | 0.00x | 0.09x | 0.21x | 0.66x |
| Net DebtTotal debt minus cash | -$4M | -$53M | $40M | -$129M |
| Cash & Equiv.Liquid assets | $4M | $78M | $355M | $147M |
| Total DebtShort + long-term debt | $57,170 | $25M | $395M | $18M |
| Interest CoverageEBIT ÷ Interest expense | -430.61x | — | — | — |
Total Returns (Dividends Reinvested)
CRSP leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CRSP five years ago would be worth $4,867 today (with dividends reinvested), compared to $17 for KPRX. Over the past 12 months, EDIT leads with a +127.8% total return vs RCKT's -45.2%. The 3-year compound annual growth rate (CAGR) favors CRSP at -2.2% vs KPRX's -52.4% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +21.3% | +6.1% | -2.5% | +47.8% |
| 1-Year ReturnPast 12 months | -26.9% | -45.2% | +53.1% | +127.8% |
| 3-Year ReturnCumulative with dividends | -89.2% | -82.8% | -6.3% | -68.5% |
| 5-Year ReturnCumulative with dividends | -99.8% | -91.6% | -51.3% | -91.1% |
| 10-Year ReturnCumulative with dividends | -100.0% | -91.3% | +272.0% | -90.0% |
| CAGR (3Y)Annualised 3-year return | -52.4% | -44.4% | -2.2% | -32.0% |
Risk & Volatility
Evenly matched — RCKT and CRSP each lead in 1 of 2 comparable metrics.
Risk & Volatility
KPRX is the less volatile stock with a 1.29 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CRSP currently trades 66.8% from its 52-week high vs RCKT's 49.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.30x | 1.21x | 1.87x | 2.45x |
| 52-Week HighHighest price in past year | $4.18 | $7.39 | $78.48 | $4.54 |
| 52-Week LowLowest price in past year | $1.76 | $2.19 | $33.50 | $1.29 |
| % of 52W HighCurrent price vs 52-week peak | +58.6% | +49.7% | +66.8% | +66.7% |
| RSI (14)Momentum oscillator 0–100 | 60.2 | 54.4 | 55.5 | 57.5 |
| Avg Volume (50D)Average daily shares traded | 597K | 3.5M | 2.0M | 1.6M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: RCKT as "Buy", CRSP as "Buy", EDIT as "Buy". Consensus price targets imply 65.0% upside for EDIT (target: $5) vs 20.2% for CRSP (target: $63).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $5.00 | $63.00 | $5.00 |
| # AnalystsCovering analysts | — | 19 | 38 | 25 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
KPRX leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). CRSP leads in 1 (Total Returns). 1 tied.
KPRX vs RCKT vs CRSP vs EDIT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is KPRX or RCKT or CRSP or EDIT a better buy right now?
For growth investors, CRISPR Therapeutics AG (CRSP) is the stronger pick with -90.
0% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Kiora Pharmaceuticals, Inc. (KPRX) offers the better valuation at 2. 8x trailing P/E, making it the more compelling value choice. Analysts rate Rocket Pharmaceuticals, Inc. (RCKT) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — KPRX or RCKT or CRSP or EDIT?
Over the past 5 years, CRISPR Therapeutics AG (CRSP) delivered a total return of -51.
3%, compared to -99. 8% for Kiora Pharmaceuticals, Inc. (KPRX). Over 10 years, the gap is even starker: CRSP returned +289. 1% versus KPRX's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — KPRX or RCKT or CRSP or EDIT?
By beta (market sensitivity over 5 years), Rocket Pharmaceuticals, Inc.
(RCKT) is the lower-risk stock at 1. 21β versus Editas Medicine, Inc. 's 2. 45β — meaning EDIT is approximately 102% more volatile than RCKT relative to the S&P 500. On balance sheet safety, Kiora Pharmaceuticals, Inc. (KPRX) carries a lower debt/equity ratio of 0% versus 66% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — KPRX or RCKT or CRSP or EDIT?
By revenue growth (latest reported year), CRISPR Therapeutics AG (CRSP) is pulling ahead at -90.
0% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Kiora Pharmaceuticals, Inc. grew EPS 103. 6% year-over-year, compared to -49. 1% for CRISPR Therapeutics AG. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — KPRX or RCKT or CRSP or EDIT?
Kiora Pharmaceuticals, Inc.
(KPRX) is the more profitable company, earning 22. 5% net margin versus -165. 7% for CRISPR Therapeutics AG — meaning it keeps 22. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KPRX leads at 28. 2% versus -161. 9% for CRSP. At the gross margin level — before operating expenses — KPRX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — KPRX or RCKT or CRSP or EDIT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is KPRX or RCKT or CRSP or EDIT better for a retirement portfolio?
For long-horizon retirement investors, Rocket Pharmaceuticals, Inc.
(RCKT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 21)). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 45 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (RCKT: -91. 4%, EDIT: -89. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between KPRX and RCKT and CRSP and EDIT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: KPRX is a small-cap deep-value stock; RCKT is a small-cap quality compounder stock; CRSP is a small-cap quality compounder stock; EDIT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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