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LTRN vs RXRX vs SDGR vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Medical - Healthcare Information Services
Biotechnology
LTRN vs RXRX vs SDGR vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Medical - Healthcare Information Services | Biotechnology |
| Market Cap | $23M | $1.48B | $981M | $5.88B |
| Revenue (TTM) | $0.00 | $66M | $255M | $0.00 |
| Net Income (TTM) | $-19M | $-560M | $-103M | $-464M |
| Gross Margin | — | -34.4% | 55.3% | — |
| Operating Margin | — | -8.8% | -64.7% | — |
| Total Debt | $244K | $78M | $109M | $98K |
| Cash & Equiv. | $8M | $743M | $231M | $714M |
LTRN vs RXRX vs SDGR vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Apr 21 | May 26 | Return |
|---|---|---|---|
| Lantern Pharma Inc. (LTRN) | 100 | 14.0 | -86.0% |
| Recursion Pharmaceu… (RXRX) | 100 | 9.9 | -90.1% |
| Schrödinger, Inc. (SDGR) | 100 | 17.2 | -82.8% |
| Immunovant, Inc. (IMVT) | 100 | 184.6 | +84.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: LTRN vs RXRX vs SDGR vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
LTRN lags the leaders in this set but could rank higher in a more targeted comparison.
RXRX is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 26.9%, EPS growth 14.8%, 3Y rev CAGR 23.5%
- 26.9% revenue growth vs IMVT's -21.3%
SDGR is the clearest fit if your priority is efficiency.
- -15.3% ROA vs LTRN's -97.4%, ROIC -39.4% vs -100.6%
IMVT carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- beta 1.36
- 190.9% 10Y total return vs SDGR's -54.2%
- Lower volatility, beta 1.36, Low D/E 0.0%, current ratio 11.16x
- Beta 1.36, current ratio 11.16x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 26.9% revenue growth vs IMVT's -21.3% | |
| Quality / Margins | 3.2% margin vs RXRX's -8.4% | |
| Stability / Safety | Beta 1.36 vs RXRX's 2.99, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +102.4% vs LTRN's -45.6% | |
| Efficiency (ROA) | -15.3% ROA vs LTRN's -97.4%, ROIC -39.4% vs -100.6% |
LTRN vs RXRX vs SDGR vs IMVT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
LTRN vs RXRX vs SDGR vs IMVT — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
SDGR leads in 2 of 6 categories
IMVT leads 2 • LTRN leads 0 • RXRX leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
SDGR leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
SDGR and IMVT operate at a comparable scale, with $255M and $0 in trailing revenue. Profitability is closely matched — net margins range from -40.6% (SDGR) to -8.4% (RXRX). On growth, SDGR holds the edge at -1.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $66M | $255M | $0 |
| EBITDAEarnings before interest/tax | -$20M | -$501M | -$159M | -$487M |
| Net IncomeAfter-tax profit | -$19M | -$560M | -$103M | -$464M |
| Free Cash FlowCash after capex | -$17M | -$326M | -$148M | -$423M |
| Gross MarginGross profit ÷ Revenue | — | -34.4% | +55.3% | — |
| Operating MarginEBIT ÷ Revenue | — | -8.8% | -64.7% | — |
| Net MarginNet income ÷ Revenue | — | -8.4% | -40.6% | — |
| FCF MarginFCF ÷ Revenue | — | -4.9% | -58.2% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -56.1% | -1.6% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +7.1% | +56.0% | +1.2% | +19.7% |
Valuation Metrics
Evenly matched — LTRN and SDGR and IMVT each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $23M | $1.5B | $981M | $5.9B |
| Enterprise ValueMkt cap + debt − cash | $16M | $819M | $860M | $5.2B |
| Trailing P/EPrice ÷ TTM EPS | -0.00x | -2.31x | -9.31x | -10.60x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 19.88x | 3.83x | — |
| Price / BookPrice ÷ Book value/share | 1.07x | 1.31x | 2.65x | 6.20x |
| Price / FCFMarket cap ÷ FCF | — | — | 78.76x | — |
Profitability & Efficiency
SDGR leads this category, winning 5 of 8 comparable metrics.
Profitability & Efficiency
SDGR delivers a -30.8% return on equity — every $100 of shareholder capital generates $-31 in annual profit, vs $-126 for LTRN. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to SDGR's 0.30x. On the Piotroski fundamental quality scale (0–9), RXRX scores 4/9 vs IMVT's 2/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -126.0% | -54.3% | -30.8% | -47.1% |
| ROA (TTM)Return on assets | -97.4% | -40.6% | -15.3% | -44.1% |
| ROICReturn on invested capital | -100.6% | -95.8% | -39.4% | — |
| ROCEReturn on capital employed | -71.4% | -50.1% | -28.6% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 4 | 4 | 2 |
| Debt / EquityFinancial leverage | 0.01x | 0.07x | 0.30x | 0.00x |
| Net DebtTotal debt minus cash | -$7M | -$665M | -$121M | -$714M |
| Cash & Equiv.Liquid assets | $8M | $743M | $231M | $714M |
| Total DebtShort + long-term debt | $243,657 | $78M | $109M | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | — | -342.92x | — | — |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $18,445 today (with dividends reinvested), compared to $1,392 for LTRN. Over the past 12 months, IMVT leads with a +102.4% total return vs LTRN's -45.6%. The 3-year compound annual growth rate (CAGR) favors IMVT at 14.4% vs LTRN's -26.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -32.5% | -21.0% | -27.0% | +11.7% |
| 1-Year ReturnPast 12 months | -45.6% | -24.4% | -45.0% | +102.4% |
| 3-Year ReturnCumulative with dividends | -60.4% | -40.7% | -52.7% | +49.8% |
| 5-Year ReturnCumulative with dividends | -86.1% | -85.6% | -79.5% | +84.4% |
| 10-Year ReturnCumulative with dividends | -86.0% | -81.6% | -54.2% | +190.9% |
| CAGR (3Y)Annualised 3-year return | -26.6% | -16.0% | -22.1% | +14.4% |
Risk & Volatility
IMVT leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
IMVT is the less volatile stock with a 1.36 beta — it tends to amplify market swings less than RXRX's 2.99 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 96.2% from its 52-week high vs LTRN's 36.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.49x | 2.99x | 1.65x | 1.36x |
| 52-Week HighHighest price in past year | $5.74 | $7.18 | $27.63 | $30.09 |
| 52-Week LowLowest price in past year | $1.11 | $2.80 | $10.95 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +36.6% | +46.2% | +47.5% | +96.2% |
| RSI (14)Momentum oscillator 0–100 | 44.2 | 44.4 | 62.7 | 50.6 |
| Avg Volume (50D)Average daily shares traded | 693K | 12.5M | 1.3M | 1.4M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: RXRX as "Hold", SDGR as "Buy", IMVT as "Buy". Consensus price targets imply 231.3% upside for RXRX (target: $11) vs 37.1% for SDGR (target: $18).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | — | $11.00 | $18.00 | $45.50 |
| # AnalystsCovering analysts | — | 10 | 12 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
SDGR leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IMVT leads in 2 (Total Returns, Risk & Volatility). 1 tied.
LTRN vs RXRX vs SDGR vs IMVT: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is LTRN or RXRX or SDGR or IMVT a better buy right now?
For growth investors, Recursion Pharmaceuticals, Inc.
(RXRX) is the stronger pick with 26. 9% revenue growth year-over-year, versus 23. 3% for Schrödinger, Inc. (SDGR). Analysts rate Schrödinger, Inc. (SDGR) a "Buy" — based on 12 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — LTRN or RXRX or SDGR or IMVT?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +84. 4%, compared to -86. 1% for Lantern Pharma Inc. (LTRN). Over 10 years, the gap is even starker: IMVT returned +190. 9% versus LTRN's -86. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — LTRN or RXRX or SDGR or IMVT?
By beta (market sensitivity over 5 years), Immunovant, Inc.
(IMVT) is the lower-risk stock at 1. 36β versus Recursion Pharmaceuticals, Inc. 's 2. 99β — meaning RXRX is approximately 120% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 30% for Schrödinger, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — LTRN or RXRX or SDGR or IMVT?
By revenue growth (latest reported year), Recursion Pharmaceuticals, Inc.
(RXRX) is pulling ahead at 26. 9% versus 23. 3% for Schrödinger, Inc. (SDGR). On earnings-per-share growth, the picture is similar: Schrödinger, Inc. grew EPS 45. 1% year-over-year, compared to -1312. 6% for Lantern Pharma Inc.. Over a 3-year CAGR, RXRX leads at 23. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — LTRN or RXRX or SDGR or IMVT?
Lantern Pharma Inc.
(LTRN) is the more profitable company, earning 0. 0% net margin versus -863. 4% for Recursion Pharmaceuticals, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LTRN leads at 0. 0% versus -867. 9% for RXRX. At the gross margin level — before operating expenses — SDGR leads at 55. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — LTRN or RXRX or SDGR or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is LTRN or RXRX or SDGR or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Immunovant, Inc.
(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+190. 9% 10Y return). Lantern Pharma Inc. (LTRN) carries a higher beta of 2. 49 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +190. 9%, LTRN: -86. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between LTRN and RXRX and SDGR and IMVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: LTRN is a small-cap quality compounder stock; RXRX is a small-cap high-growth stock; SDGR is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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