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MAIA vs TELO vs NKTR vs ILMN vs TMO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MAIA
MAIA Biotechnology, Inc.

Biotechnology

HealthcareAMEX • US
Market Cap$55M
5Y Perf.+14.5%
TELO
Telomir Pharmaceuticals, Inc. Common Stock

Biotechnology

HealthcareNASDAQ • US
Market Cap$42M
5Y Perf.-86.0%
NKTR
Nektar Therapeutics

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.16B
5Y Perf.+456.9%
ILMN
Illumina, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$25.97B
5Y Perf.+23.7%
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$176.13B
5Y Perf.-15.5%

MAIA vs TELO vs NKTR vs ILMN vs TMO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MAIA logoMAIA
TELO logoTELO
NKTR logoNKTR
ILMN logoILMN
TMO logoTMO
IndustryBiotechnologyBiotechnologyBiotechnologyMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$55M$42M$1.16B$25.97B$176.13B
Revenue (TTM)$0.00$0.00$56M$4.39B$45.20B
Net Income (TTM)$-24M$-9M$-158M$853M$6.86B
Gross Margin99.4%67.1%39.4%
Operating Margin-224.9%20.9%17.8%
Forward P/E32.2x19.4x
Total Debt$0.00$0.00$149M$2.55B$40.85B
Cash & Equiv.$8.66B$7M$15M$1.42B$9.86B

MAIA vs TELO vs NKTR vs ILMN vs TMOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MAIA
TELO
NKTR
ILMN
TMO
StockFeb 24Jun 26Return
MAIA Biotechnology,… (MAIA)100114.5+14.5%
Telomir Pharmaceuti… (TELO)10014.0-86.0%
Nektar Therapeutics (NKTR)100556.9+456.9%
Illumina, Inc. (ILMN)100123.7+23.7%
Thermo Fisher Scien… (TMO)10084.5-15.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: MAIA vs TELO vs NKTR vs ILMN vs TMO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ILMN leads in 3 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Thermo Fisher Scientific Inc. is the stronger pick specifically for capital preservation and lower volatility and dividend income and shareholder returns. TELO and NKTR also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
MAIA
MAIA Biotechnology, Inc.
The Healthcare Pick

Among these 5 stocks, MAIA doesn't own a clear edge in any measured category.

Best for: healthcare exposure
TELO
Telomir Pharmaceuticals, Inc. Common Stock
The Growth Leader

TELO ranks third and is worth considering specifically for growth.

  • 241.7% revenue growth vs NKTR's -43.9%
Best for: growth
NKTR
Nektar Therapeutics
The Momentum Pick

NKTR is the clearest fit if your priority is momentum.

  • +485.3% vs TELO's -39.7%
Best for: momentum
ILMN
Illumina, Inc.
The Value Pick

ILMN carries the broadest edge in this set and is the clearest fit for valuation efficiency.

  • PEG 7.61 vs TMO's 9.18
  • Better valuation composite
  • 19.4% margin vs NKTR's -284.2%
  • 13.4% ROA vs TELO's -172.7%
Best for: valuation efficiency
TMO
Thermo Fisher Scientific Inc.
The Income Pick

TMO is the #2 pick in this set and the best alternative if income & stability and growth exposure is your priority.

  • Dividend streak 8 yrs, beta 0.95, yield 0.4%
  • Rev growth 3.9%, EPS growth 7.3%, 3Y rev CAGR -0.3%
  • 217.1% 10Y total return vs ILMN's 20.8%
  • Lower volatility, beta 0.95, Low D/E 76.3%, current ratio 1.89x
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthTELO logoTELO241.7% revenue growth vs NKTR's -43.9%
ValueILMN logoILMNBetter valuation composite
Quality / MarginsILMN logoILMN19.4% margin vs NKTR's -284.2%
Stability / SafetyTMO logoTMOBeta 0.95 vs TELO's 1.95
DividendsTMO logoTMO0.4% yield; 8-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)NKTR logoNKTR+485.3% vs TELO's -39.7%
Efficiency (ROA)ILMN logoILMN13.4% ROA vs TELO's -172.7%

MAIA vs TELO vs NKTR vs ILMN vs TMO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MAIAMAIA Biotechnology, Inc.

Segment breakdown not available.

TELOTelomir Pharmaceuticals, Inc. Common Stock

Segment breakdown not available.

NKTRNektar Therapeutics
FY 2025
Non Cash Royalty Revenue Related To Sale Of Future Royalties
99.5%$55M
License Collaboration And Other Revenue
0.5%$300,000
ILMNIllumina, Inc.
FY 2025
Sequencing
91.8%$4.0B
Microarray
8.2%$358M
TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B

MAIA vs TELO vs NKTR vs ILMN vs TMO — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLILMNLAGGINGTELO

Income & Cash Flow (Last 12 Months)

ILMN leads this category, winning 3 of 6 comparable metrics.

TMO and TELO operate at a comparable scale, with $45.2B and $0 in trailing revenue. ILMN is the more profitable business, keeping 19.4% of every revenue dollar as net income compared to NKTR's -2.8%.

MetricMAIA logoMAIAMAIA Biotechnolog…TELO logoTELOTelomir Pharmaceu…NKTR logoNKTRNektar Therapeuti…ILMN logoILMNIllumina, Inc.TMO logoTMOThermo Fisher Sci…
RevenueTrailing 12 months$0$0$56M$4.4B$45.2B
EBITDAEarnings before interest/tax-$16M-$9M-$124M$1.1B$10.5B
Net IncomeAfter-tax profit-$24M-$9M-$158M$853M$6.9B
Free Cash FlowCash after capex-$20M-$5M-$204M$989M$6.7B
Gross MarginGross profit ÷ Revenue+99.4%+67.1%+39.4%
Operating MarginEBIT ÷ Revenue-2.2%+20.9%+17.8%
Net MarginNet income ÷ Revenue-2.8%+19.4%+15.2%
FCF MarginFCF ÷ Revenue-3.7%+22.5%+14.9%
Rev. Growth (YoY)Latest quarter vs prior year+3.8%+4.8%+6.2%
EPS Growth (YoY)Latest quarter vs prior year+12.5%+59.0%+49.7%+6.1%+11.3%
ILMN leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

TMO leads this category, winning 4 of 7 comparable metrics.

At 26.7x trailing earnings, TMO trades at a 15% valuation discount to ILMN's 31.4x P/E. Adjusting for growth (PEG ratio), ILMN offers better value at 7.41x vs TMO's 12.65x — a lower PEG means you pay less per unit of expected earnings growth.

MetricMAIA logoMAIAMAIA Biotechnolog…TELO logoTELOTelomir Pharmaceu…NKTR logoNKTRNektar Therapeuti…ILMN logoILMNIllumina, Inc.TMO logoTMOThermo Fisher Sci…
Market CapShares × price$55M$42M$1.2B$26.0B$176.1B
Enterprise ValueMkt cap + debt − cash-$8.6B$35M$1.3B$27.1B$207.1B
Trailing P/EPrice ÷ TTM EPS-2.04x-3.73x-6.09x31.36x26.72x
Forward P/EPrice ÷ next-FY EPS est.32.19x19.38x
PEG RatioP/E ÷ EPS growth rate7.41x12.65x
EV / EBITDAEnterprise value multiple23.90x19.02x
Price / SalesMarket cap ÷ Revenue20.96x5.99x3.95x
Price / BookPrice ÷ Book value/share19.33x6.58x11.12x9.79x3.34x
Price / FCFMarket cap ÷ FCF27.89x27.99x
TMO leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

ILMN leads this category, winning 6 of 9 comparable metrics.

ILMN delivers a 32.8% return on equity — every $100 of shareholder capital generates $33 in annual profit, vs $-2 for TELO. TMO carries lower financial leverage with a 0.76x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), ILMN scores 8/9 vs NKTR's 2/9, reflecting strong financial health.

MetricMAIA logoMAIAMAIA Biotechnolog…TELO logoTELOTelomir Pharmaceu…NKTR logoNKTRNektar Therapeuti…ILMN logoILMNIllumina, Inc.TMO logoTMOThermo Fisher Sci…
ROE (TTM)Return on equity-4.0%-2.0%-87.0%+32.8%+13.2%
ROA (TTM)Return on assets-1.0%-172.7%-40.7%+13.4%+6.4%
ROICReturn on invested capital-57.2%+16.8%+7.5%
ROCEReturn on capital employed-4.8%-3.2%-55.7%+17.6%+9.1%
Piotroski ScoreFundamental quality 0–923286
Debt / EquityFinancial leverage1.66x0.94x0.76x
Net DebtTotal debt minus cash-$8.7B-$7M$134M$1.1B$31.0B
Cash & Equiv.Liquid assets$8.7B$7M$15M$1.4B$9.9B
Total DebtShort + long-term debt$0$0$149M$2.6B$40.9B
Interest CoverageEBIT ÷ Interest expense-1740.57x-4.15x12.09x5.89x
ILMN leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NKTR leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in TMO five years ago would be worth $10,803 today (with dividends reinvested), compared to $1,757 for TELO. Over the past 12 months, NKTR leads with a +485.3% total return vs TELO's -39.7%. The 3-year compound annual growth rate (CAGR) favors NKTR at 86.4% vs TELO's -44.0% — a key indicator of consistent wealth creation.

MetricMAIA logoMAIAMAIA Biotechnolog…TELO logoTELOTelomir Pharmaceu…NKTR logoNKTRNektar Therapeuti…ILMN logoILMNIllumina, Inc.TMO logoTMOThermo Fisher Sci…
YTD ReturnYear-to-date-10.6%-8.2%+36.4%+27.2%-19.9%
1-Year ReturnPast 12 months-18.3%-39.7%+485.3%+108.9%+18.9%
3-Year ReturnCumulative with dividends-39.1%-82.4%+547.3%-16.5%-7.7%
5-Year ReturnCumulative with dividends-67.9%-82.4%-77.9%-56.5%+8.0%
10-Year ReturnCumulative with dividends-67.9%-82.4%-75.1%+20.8%+217.1%
CAGR (3Y)Annualised 3-year return-15.3%-44.0%+86.4%-5.8%-2.6%
NKTR leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ILMN and TMO each lead in 1 of 2 comparable metrics.

TMO is the less volatile stock with a 0.95 beta — it tends to amplify market swings less than TELO's 1.95 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ILMN currently trades 99.1% from its 52-week high vs TELO's 39.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMAIA logoMAIAMAIA Biotechnolog…TELO logoTELOTelomir Pharmaceu…NKTR logoNKTRNektar Therapeuti…ILMN logoILMNIllumina, Inc.TMO logoTMOThermo Fisher Sci…
Beta (5Y)Sensitivity to S&P 5001.71x1.95x1.68x1.06x0.95x
52-Week HighHighest price in past year$3.19$3.10$109.00$172.49$643.99
52-Week LowLowest price in past year$0.87$1.05$7.99$78.79$385.46
% of 52W HighCurrent price vs 52-week peak+44.8%+39.7%+54.3%+99.1%+73.6%
RSI (14)Momentum oscillator 0–10052.442.522.075.655.9
Avg Volume (50D)Average daily shares traded737K145K1.0M1.6M2.0M
Evenly matched — ILMN and TMO each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: NKTR as "Buy", ILMN as "Buy", TMO as "Buy". Consensus price targets imply 152.6% upside for NKTR (target: $150) vs -12.0% for ILMN (target: $150). TMO is the only dividend payer here at 0.36% yield — a key consideration for income-focused portfolios.

MetricMAIA logoMAIAMAIA Biotechnolog…TELO logoTELOTelomir Pharmaceu…NKTR logoNKTRNektar Therapeuti…ILMN logoILMNIllumina, Inc.TMO logoTMOThermo Fisher Sci…
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$149.60$150.40$638.20
# AnalystsCovering analysts335042
Dividend YieldAnnual dividend ÷ price+0.4%
Dividend StreakConsecutive years of raises8
Dividend / ShareAnnual DPS$1.69
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+2.9%+1.7%
Insufficient data to determine a leader in this category.
Key Takeaway

ILMN leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). TMO leads in 1 (Valuation Metrics). 1 tied.

Best OverallIllumina, Inc. (ILMN)Leads 2 of 6 categories
Loading custom metrics...

MAIA vs TELO vs NKTR vs ILMN vs TMO: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is MAIA or TELO or NKTR or ILMN or TMO a better buy right now?

For growth investors, Thermo Fisher Scientific Inc.

(TMO) is the stronger pick with 3. 9% revenue growth year-over-year, versus -43. 9% for Nektar Therapeutics (NKTR). Thermo Fisher Scientific Inc. (TMO) offers the better valuation at 26. 7x trailing P/E (19. 4x forward), making it the more compelling value choice. Analysts rate Nektar Therapeutics (NKTR) a "Buy" — based on 33 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MAIA or TELO or NKTR or ILMN or TMO?

On trailing P/E, Thermo Fisher Scientific Inc.

(TMO) is the cheapest at 26. 7x versus Illumina, Inc. at 31. 4x. On forward P/E, Thermo Fisher Scientific Inc. is actually cheaper at 19. 4x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Illumina, Inc. wins at 7. 61x versus Thermo Fisher Scientific Inc. 's 9. 18x.

03

Which is the better long-term investment — MAIA or TELO or NKTR or ILMN or TMO?

Over the past 5 years, Thermo Fisher Scientific Inc.

(TMO) delivered a total return of +8. 0%, compared to -82. 4% for Telomir Pharmaceuticals, Inc. Common Stock (TELO). Over 10 years, the gap is even starker: TMO returned +221. 7% versus TELO's -81. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MAIA or TELO or NKTR or ILMN or TMO?

By beta (market sensitivity over 5 years), Thermo Fisher Scientific Inc.

(TMO) is the lower-risk stock at 0. 95β versus Telomir Pharmaceuticals, Inc. Common Stock's 1. 95β — meaning TELO is approximately 106% more volatile than TMO relative to the S&P 500. On balance sheet safety, Thermo Fisher Scientific Inc. (TMO) carries a lower debt/equity ratio of 76% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.

05

Which is growing faster — MAIA or TELO or NKTR or ILMN or TMO?

By revenue growth (latest reported year), Thermo Fisher Scientific Inc.

(TMO) is pulling ahead at 3. 9% versus -43. 9% for Nektar Therapeutics (NKTR). On earnings-per-share growth, the picture is similar: Illumina, Inc. grew EPS 170. 9% year-over-year, compared to -12. 1% for Nektar Therapeutics. Over a 3-year CAGR, TMO leads at -0. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MAIA or TELO or NKTR or ILMN or TMO?

Illumina, Inc.

(ILMN) is the more profitable company, earning 19. 6% net margin versus -297. 1% for Nektar Therapeutics — meaning it keeps 19. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ILMN leads at 19. 9% versus -236. 8% for NKTR. At the gross margin level — before operating expenses — NKTR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MAIA or TELO or NKTR or ILMN or TMO more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Illumina, Inc. (ILMN) is the more undervalued stock at a PEG of 7. 61x versus Thermo Fisher Scientific Inc. 's 9. 18x. Both stocks trade at elevated growth-adjusted valuations, so expected growth needs to materialise. On forward earnings alone, Thermo Fisher Scientific Inc. (TMO) trades at 19. 4x forward P/E versus 32. 2x for Illumina, Inc. — 12. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NKTR: 152. 6% to $149. 60.

08

Which pays a better dividend — MAIA or TELO or NKTR or ILMN or TMO?

In this comparison, TMO (0.

4% yield) pays a dividend. MAIA, TELO, NKTR, ILMN do not pay a meaningful dividend and should not be held primarily for income.

09

Is MAIA or TELO or NKTR or ILMN or TMO better for a retirement portfolio?

For long-horizon retirement investors, Thermo Fisher Scientific Inc.

(TMO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 95), +221. 7% 10Y return). Telomir Pharmaceuticals, Inc. Common Stock (TELO) carries a higher beta of 1. 95 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (TMO: +221. 7%, TELO: -81. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MAIA and TELO and NKTR and ILMN and TMO?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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