Illumina, Inc. (ILMN) P/E Ratio History
Historical price-to-earnings valuation from 2006 to 2026
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ILMN Valuation Context
How does the current P/E compare to historical and market benchmarks?
P/E Ratio Analysis
As of May 10, 2026, Illumina, Inc. (ILMN) trades at a price-to-earnings ratio of 25.5x, with a stock price of $138.71 and trailing twelve-month earnings per share of $5.54.
The current P/E is 55% below its 5-year average of 56.3x. Over the past five years, ILMN's P/E has ranged from a low of 12.0x to a high of 88.4x, placing the current valuation at the 20th percentile of its historical range.
Compared to the Healthcare sector median P/E of 22.3x, ILMN is roughly in line with its sector peers. The sector includes 241 companies with P/E ratios ranging from 0.0x to 177.5x.
The PEG ratio of 6.01 (P/E divided by 171% EPS growth) suggests the stock may be expensive relative to its earnings growth. Peter Lynch popularized the rule that a PEG below 1.0 indicates an attractive entry point.
Relative to the broader market, ILMN trades roughly in line with the S&P 500 median P/E of 25.1x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our ILMN DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
ILMN P/E vs Peers
P/E ratio compared to closely matched public peers
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $176B | 26.8 | 12.67 | +7% | |
| $124B | 34.9 | - | -5% | |
| $34B | 26.0 | 1.76Best | +3% | |
| $7B | 9.2Lowest | - | +143%Best |
Peers sorted by market capitalization. P/E below peers may indicate undervaluation or lower growth expectations. Consider PEG ratio for growth-adjusted comparison.
ILMN Historical P/E Data (2006–2026)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Date | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2026 Q1 | Sun Mar 29 2026 00:00:00 GM | $117.67 | $5.51 | 21.4x | -70% |
| FY2025 Q4 | Sun Dec 28 2025 00:00:00 GM | $134.95 | $5.46 | 24.7x | -66% |
| FY2025 Q3 | Sun Sep 28 2025 00:00:00 GM | $91.69 | $4.46 | 20.6x | -71% |
| FY2025 Q2 | Sun Jun 29 2025 00:00:00 GM | $94.79 | $7.90 | 12.0x | -83% |
| FY2022 Q1 | Sun Apr 03 2022 00:00:00 GM | $353.65 | $4.58 | 77.2x | +7% |
| FY2021 Q4 | Fri Dec 31 2021 00:00:00 GM | $369.72 | $5.04 | 73.4x | +2% |
| FY2021 Q3 | Sun Oct 03 2021 00:00:00 GM | $383.72 | $6.08 | 63.1x | -12% |
| FY2021 Q2 | Sun Jul 04 2021 00:00:00 GM | $461.36 | $5.22 | 88.4x | +23% |
| FY2021 Q1 | Sun Apr 04 2021 00:00:00 GM | $374.19 | $4.28 | 87.5x | +21% |
| FY2020 Q4 | $359.58 | $4.45 | 80.8x | +12% | |
| FY2020 Q3 | Sun Sep 27 2020 00:00:00 GM | $291.44 | $4.31 | 67.5x | -6% |
| FY2020 Q2 | Sun Jun 28 2020 00:00:00 GM | $349.94 | $4.68 | 74.7x | +4% |
Average P/E for displayed period: 72.1x
Full ILMN Stock Analysis
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Start ComparisonILMN — Frequently Asked Questions
Quick answers to the most common questions about buying ILMN stock.
Is ILMN stock overvalued or undervalued?
ILMN trades at 25.5x P/E, below its 5-year average of 56.3x. At the 20th percentile of historical range, the stock is priced at a discount to its own history.
How does ILMN's valuation compare to peers?
Illumina, Inc. P/E of 25.5x compares to sector median of 22.3x. The premium reflects expected growth above peers.
What is ILMN's PEG ratio?
ILMN PEG ratio is 6.01. Above 2.0 indicates premium valuation relative to growth rate. Historical P/E data spans 2006-2026.