Biotechnology
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5 / 10Stock Comparison
MBRX vs TPVG vs SNDX vs HRZN vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Asset Management
Biotechnology
Asset Management
Biotechnology
MBRX vs TPVG vs SNDX vs HRZN vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Asset Management | Biotechnology | Asset Management | Biotechnology |
| Market Cap | $29M | $243M | $1.81B | $199M | $5.53B |
| Revenue (TTM) | $0.00 | $97M | $217M | $40M | $0.00 |
| Net Income (TTM) | $-24M | $-12M | $-243M | $28M | $-464M |
| Gross Margin | — | 83.5% | 98.0% | 18.0% | — |
| Operating Margin | — | 77.9% | -102.9% | -4.0% | — |
| Forward P/E | — | 6.5x | — | 6.1x | — |
| Total Debt | $222K | $469M | $346M | $473M | $98K |
| Cash & Equiv. | $9M | $20M | $135M | $106M | $714M |
MBRX vs TPVG vs SNDX vs HRZN vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Moleculin Biotech, … (MBRX) | 100 | 2.5 | -97.5% |
| TriplePoint Venture… (TPVG) | 100 | 59.8 | -40.2% |
| Syndax Pharmaceutic… (SNDX) | 100 | 126.8 | +26.8% |
| Horizon Technology … (HRZN) | 100 | 41.4 | -58.6% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MBRX vs TPVG vs SNDX vs HRZN vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
MBRX is the #2 pick in this set and the best alternative if momentum is your priority.
- +149.2% vs HRZN's -23.2%
TPVG ranks third and is worth considering specifically for bank quality.
- NIM 7.4% vs HRZN's 7.1%
- 50.6% margin vs SNDX's -112.0%
SNDX is the clearest fit if your priority is growth exposure.
- Rev growth 6.3%, EPS growth 11.8%
- 6.3% revenue growth vs IMVT's -21.3%
HRZN carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- Dividend streak 0 yrs, beta 0.70, yield 27.8%
- Lower volatility, beta 0.70, current ratio 1.24x
- PEG 0.26 vs TPVG's 6.41
- Beta 0.70, yield 27.8%, current ratio 1.24x
IMVT is the clearest fit if your priority is long-term compounding.
- 173.6% 10Y total return vs TPVG's 93.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 6.3% revenue growth vs IMVT's -21.3% | |
| Value | Better valuation composite | |
| Quality / Margins | 50.6% margin vs SNDX's -112.0% | |
| Stability / Safety | Beta 0.70 vs IMVT's 1.37 | |
| Dividends | 27.8% yield, vs MBRX's 0.4%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +149.2% vs HRZN's -23.2% | |
| Efficiency (ROA) | 3.6% ROA vs MBRX's -112.5%, ROIC -0.2% vs -441.5% |
MBRX vs TPVG vs SNDX vs HRZN vs IMVT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
MBRX vs TPVG vs SNDX vs HRZN vs IMVT — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HRZN leads in 2 of 6 categories
TPVG leads 1 • IMVT leads 1 • MBRX leads 0 • SNDX leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
TPVG leads this category, winning 2 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
SNDX and IMVT operate at a comparable scale, with $217M and $0 in trailing revenue. TPVG is the more profitable business, keeping 50.6% of every revenue dollar as net income compared to SNDX's -112.0%.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $97M | $217M | $40M | $0 |
| EBITDAEarnings before interest/tax | -$25M | -$22M | -$218M | $19M | -$487M |
| Net IncomeAfter-tax profit | -$24M | -$12M | -$243M | $28M | -$464M |
| Free Cash FlowCash after capex | -$23M | $35M | -$278M | $67M | -$423M |
| Gross MarginGross profit ÷ Revenue | — | +83.5% | +98.0% | +18.0% | — |
| Operating MarginEBIT ÷ Revenue | — | +77.9% | -102.9% | -4.0% | — |
| Net MarginNet income ÷ Revenue | — | +50.6% | -112.0% | -6.6% | — |
| FCF MarginFCF ÷ Revenue | — | -58.7% | -128.2% | +141.5% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +2.2% | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | +134.5% | -2.3% | +100.0% | -29.6% | +19.7% |
Valuation Metrics
HRZN leads this category, winning 3 of 5 comparable metrics.
Valuation Metrics
At 4.3x trailing earnings, HRZN trades at a 13% valuation discount to TPVG's 4.9x P/E. Adjusting for growth (PEG ratio), HRZN offers better value at 0.18x vs TPVG's 4.84x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $29M | $243M | $1.8B | $199M | $5.5B |
| Enterprise ValueMkt cap + debt − cash | $21M | $691M | $2.0B | $567M | $4.8B |
| Trailing P/EPrice ÷ TTM EPS | -0.09x | 4.91x | -6.24x | 4.30x | -9.97x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 6.50x | — | 6.10x | — |
| PEG RatioP/E ÷ EPS growth rate | — | 4.84x | — | 0.18x | — |
| EV / EBITDAEnterprise value multiple | — | 9.13x | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 2.50x | 10.51x | 4.97x | — |
| Price / BookPrice ÷ Book value/share | 1.97x | 0.68x | 27.53x | 0.60x | 5.83x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 3.51x | — |
Profitability & Efficiency
HRZN leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
HRZN delivers a 9.0% return on equity — every $100 of shareholder capital generates $9 in annual profit, vs $-3 for MBRX. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to SNDX's 5.36x. On the Piotroski fundamental quality scale (0–9), TPVG scores 5/9 vs IMVT's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -3.2% | -3.4% | -2.6% | +9.0% | -47.1% |
| ROA (TTM)Return on assets | -112.5% | -1.5% | -45.2% | +3.6% | -44.1% |
| ROICReturn on invested capital | -4.4% | +7.2% | -54.2% | -0.2% | — |
| ROCEReturn on capital employed | -187.1% | +9.4% | -53.0% | -0.2% | -66.1% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 5 | 2 | 5 | 2 |
| Debt / EquityFinancial leverage | 0.01x | 1.33x | 5.36x | 1.49x | 0.00x |
| Net DebtTotal debt minus cash | -$9M | $449M | $212M | $368M | -$714M |
| Cash & Equiv.Liquid assets | $9M | $20M | $135M | $106M | $714M |
| Total DebtShort + long-term debt | $222,000 | $469M | $346M | $473M | $98,000 |
| Interest CoverageEBIT ÷ Interest expense | — | -1.02x | -2.31x | 0.60x | — |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $496 for MBRX. Over the past 12 months, MBRX leads with a +149.2% total return vs HRZN's -23.2%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs MBRX's -40.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -31.2% | -6.3% | -3.6% | -26.7% | +5.1% |
| 1-Year ReturnPast 12 months | +149.2% | +19.3% | +105.6% | -23.2% | +96.1% |
| 3-Year ReturnCumulative with dividends | -79.2% | -3.4% | +1.2% | -27.7% | +40.9% |
| 5-Year ReturnCumulative with dividends | -95.0% | -13.5% | +28.1% | -32.8% | +62.4% |
| 10-Year ReturnCumulative with dividends | -99.7% | +93.3% | +43.4% | +52.9% | +173.6% |
| CAGR (3Y)Annualised 3-year return | -40.7% | -1.2% | +0.4% | -10.3% | +12.1% |
Risk & Volatility
Evenly matched — HRZN and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
HRZN is the less volatile stock with a 0.70 beta — it tends to amplify market swings less than IMVT's 1.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs MBRX's 31.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.22x | 0.83x | 0.81x | 0.70x | 1.37x |
| 52-Week HighHighest price in past year | $7.98 | $7.53 | $25.58 | $8.46 | $30.09 |
| 52-Week LowLowest price in past year | $0.25 | $4.48 | $8.58 | $3.80 | $13.36 |
| % of 52W HighCurrent price vs 52-week peak | +31.2% | +79.5% | +80.3% | +53.3% | +90.5% |
| RSI (14)Momentum oscillator 0–100 | 48.5 | 58.3 | 41.3 | 58.5 | 60.2 |
| Avg Volume (50D)Average daily shares traded | 110K | 504K | 1.5M | 1.2M | 1.4M |
Analyst Outlook
Evenly matched — MBRX and SNDX and HRZN each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: MBRX as "Buy", TPVG as "Hold", SNDX as "Buy", HRZN as "Hold", IMVT as "Buy". Consensus price targets imply 94.7% upside for SNDX (target: $40) vs 44.1% for HRZN (target: $7). For income investors, HRZN offers the higher dividend yield at 27.80% vs MBRX's 0.35%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Hold | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | — | $8.95 | $40.00 | $6.50 | $45.50 |
| # AnalystsCovering analysts | 4 | 12 | 22 | 22 | 23 |
| Dividend YieldAnnual dividend ÷ price | +0.4% | +17.1% | — | +27.8% | — |
| Dividend StreakConsecutive years of raises | 1 | 0 | 1 | 0 | — |
| Dividend / ShareAnnual DPS | $0.01 | $1.02 | — | $1.25 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
HRZN leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). TPVG leads in 1 (Income & Cash Flow). 2 tied.
MBRX vs TPVG vs SNDX vs HRZN vs IMVT: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is MBRX or TPVG or SNDX or HRZN or IMVT a better buy right now?
For growth investors, Syndax Pharmaceuticals, Inc.
(SNDX) is the stronger pick with 627. 8% revenue growth year-over-year, versus 17. 9% for Horizon Technology Finance Corporation (HRZN). Horizon Technology Finance Corporation (HRZN) offers the better valuation at 4. 3x trailing P/E (6. 1x forward), making it the more compelling value choice. Analysts rate Moleculin Biotech, Inc. (MBRX) a "Buy" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — MBRX or TPVG or SNDX or HRZN or IMVT?
On trailing P/E, Horizon Technology Finance Corporation (HRZN) is the cheapest at 4.
3x versus TriplePoint Venture Growth BDC Corp. at 4. 9x. On forward P/E, Horizon Technology Finance Corporation is actually cheaper at 6. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Horizon Technology Finance Corporation wins at 0. 26x versus TriplePoint Venture Growth BDC Corp. 's 6. 41x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — MBRX or TPVG or SNDX or HRZN or IMVT?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +62. 4%, compared to -95. 0% for Moleculin Biotech, Inc. (MBRX). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus MBRX's -99. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — MBRX or TPVG or SNDX or HRZN or IMVT?
By beta (market sensitivity over 5 years), Horizon Technology Finance Corporation (HRZN) is the lower-risk stock at 0.
70β versus Immunovant, Inc. 's 1. 37β — meaning IMVT is approximately 96% more volatile than HRZN relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 5% for Syndax Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — MBRX or TPVG or SNDX or HRZN or IMVT?
By revenue growth (latest reported year), Syndax Pharmaceuticals, Inc.
(SNDX) is pulling ahead at 627. 8% versus 17. 9% for Horizon Technology Finance Corporation (HRZN). On earnings-per-share growth, the picture is similar: Horizon Technology Finance Corporation grew EPS 756. 3% year-over-year, compared to -45. 2% for Immunovant, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — MBRX or TPVG or SNDX or HRZN or IMVT?
TriplePoint Venture Growth BDC Corp.
(TPVG) is the more profitable company, earning 50. 6% net margin versus -165. 6% for Syndax Pharmaceuticals, Inc. — meaning it keeps 50. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: TPVG leads at 77. 9% versus -158. 4% for SNDX. At the gross margin level — before operating expenses — SNDX leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is MBRX or TPVG or SNDX or HRZN or IMVT more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Horizon Technology Finance Corporation (HRZN) is the more undervalued stock at a PEG of 0. 26x versus TriplePoint Venture Growth BDC Corp. 's 6. 41x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Horizon Technology Finance Corporation (HRZN) trades at 6. 1x forward P/E versus 6. 5x for TriplePoint Venture Growth BDC Corp. — 0. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for SNDX: 94. 7% to $40. 00.
08Which pays a better dividend — MBRX or TPVG or SNDX or HRZN or IMVT?
In this comparison, HRZN (27.
8% yield), TPVG (17. 1% yield), MBRX (0. 4% yield) pay a dividend. SNDX, IMVT do not pay a meaningful dividend and should not be held primarily for income.
09Is MBRX or TPVG or SNDX or HRZN or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Horizon Technology Finance Corporation (HRZN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
70), 27. 8% yield). Both have compounded well over 10 years (HRZN: +52. 9%, MBRX: -99. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between MBRX and TPVG and SNDX and HRZN and IMVT?
These companies operate in different sectors (MBRX (Healthcare) and TPVG (Financial Services) and SNDX (Healthcare) and HRZN (Financial Services) and IMVT (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: MBRX is a small-cap quality compounder stock; TPVG is a small-cap high-growth stock; SNDX is a small-cap high-growth stock; HRZN is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock. TPVG, HRZN pay a dividend while MBRX, SNDX, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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- Sector: Financial Services
- Market Cap > $100B
- Revenue Growth > 8%
- Dividend Yield > 11.1%
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