Biotechnology
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5 / 10Stock Comparison
MRVI vs NUVL vs RGEN vs AZTA vs BRKR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Medical - Instruments & Supplies
Medical - Instruments & Supplies
Medical - Devices
MRVI vs NUVL vs RGEN vs AZTA vs BRKR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Medical - Instruments & Supplies | Medical - Instruments & Supplies | Medical - Devices |
| Market Cap | $436M | $7.53B | $7.13B | $855M | $6.66B |
| Revenue (TTM) | $186M | $0.00 | $763M | $597M | $3.46B |
| Net Income (TTM) | $-131M | $-450M | $51M | $-178M | $-12M |
| Gross Margin | 18.3% | — | 51.5% | 44.6% | 45.3% |
| Operating Margin | -115.9% | — | 8.7% | -26.4% | 4.9% |
| Forward P/E | — | — | 64.3x | 23.7x | 20.7x |
| Total Debt | $36M | $0.00 | $690M | $111M | $2.04B |
| Cash & Equiv. | $217M | $262M | $566M | $280M | $299M |
MRVI vs NUVL vs RGEN vs AZTA vs BRKR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 21 | May 26 | Return |
|---|---|---|---|
| Maravai LifeScience… (MRVI) | 100 | 9.0 | -91.0% |
| Nuvalent, Inc. (NUVL) | 100 | 561.1 | +461.1% |
| Repligen Corporation (RGEN) | 100 | 51.5 | -48.5% |
| Azenta, Inc. (AZTA) | 100 | 20.9 | -79.1% |
| Bruker Corporation (BRKR) | 100 | 53.2 | -46.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MRVI vs NUVL vs RGEN vs AZTA vs BRKR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
MRVI ranks third and is worth considering specifically for income & stability.
- Dividend streak 1 yrs, beta 2.03
- +85.8% vs AZTA's -26.5%
NUVL is the clearest fit if your priority is long-term compounding and sleep-well-at-night.
- 446.1% 10Y total return vs RGEN's 369.1%
- Lower volatility, beta 1.09, current ratio 15.27x
- Beta 1.09, current ratio 15.27x
- Beta 1.09 vs AZTA's 2.17
RGEN carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 16.4%, EPS growth 287.0%, 3Y rev CAGR -2.7%
- 16.4% revenue growth vs MRVI's -80.8%
- 6.7% margin vs MRVI's -70.4%
- 1.8% ROA vs MRVI's -187.0%, ROIC 2.2% vs -39.2%
Among these 5 stocks, AZTA doesn't own a clear edge in any measured category.
BRKR is the #2 pick in this set and the best alternative if value and dividends is your priority.
- Lower P/E (20.7x vs 64.3x)
- 0.3% yield; the other 4 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 16.4% revenue growth vs MRVI's -80.8% | |
| Value | Lower P/E (20.7x vs 64.3x) | |
| Quality / Margins | 6.7% margin vs MRVI's -70.4% | |
| Stability / Safety | Beta 1.09 vs AZTA's 2.17 | |
| Dividends | 0.3% yield; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +85.8% vs AZTA's -26.5% | |
| Efficiency (ROA) | 1.8% ROA vs MRVI's -187.0%, ROIC 2.2% vs -39.2% |
MRVI vs NUVL vs RGEN vs AZTA vs BRKR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
MRVI vs NUVL vs RGEN vs AZTA vs BRKR — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
RGEN leads in 2 of 6 categories
AZTA leads 1 • NUVL leads 1 • MRVI leads 1 • BRKR leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
RGEN leads this category, winning 6 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BRKR and NUVL operate at a comparable scale, with $3.5B and $0 in trailing revenue. RGEN is the more profitable business, keeping 6.7% of every revenue dollar as net income compared to MRVI's -70.4%. On growth, RGEN holds the edge at +14.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $186M | $0 | $763M | $597M | $3.5B |
| EBITDAEarnings before interest/tax | -$230M | -$346M | $155M | -$115M | $397M |
| Net IncomeAfter-tax profit | -$131M | -$450M | $51M | -$178M | -$12M |
| Free Cash FlowCash after capex | -$46M | -$313M | $104M | $29M | $51M |
| Gross MarginGross profit ÷ Revenue | +18.3% | — | +51.5% | +44.6% | +45.3% |
| Operating MarginEBIT ÷ Revenue | -115.9% | — | +8.7% | -26.4% | +4.9% |
| Net MarginNet income ÷ Revenue | -70.4% | — | +6.7% | -29.9% | -0.3% |
| FCF MarginFCF ÷ Revenue | -24.7% | — | +13.7% | +4.8% | +1.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | -11.6% | — | +14.8% | +1.0% | +2.7% |
| EPS Growth (YoY)Latest quarter vs prior year | -33.3% | -17.8% | +50.0% | -3.0% | -79.2% |
Valuation Metrics
AZTA leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
On an enterprise value basis, AZTA's 13.8x EV/EBITDA is more attractive than RGEN's 52.4x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $436M | $7.5B | $7.1B | $855M | $6.7B |
| Enterprise ValueMkt cap + debt − cash | $255M | $7.3B | $7.3B | $687M | $8.4B |
| Trailing P/EPrice ÷ TTM EPS | -16.42x | -17.50x | 147.01x | -15.22x | -291.53x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 64.26x | 23.68x | 20.68x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | 52.45x | 13.75x | 18.41x |
| Price / SalesMarket cap ÷ Revenue | 8.75x | — | 9.66x | 1.44x | 1.94x |
| Price / BookPrice ÷ Book value/share | 1.53x | 5.96x | 3.40x | 0.49x | 2.64x |
| Price / FCFMarket cap ÷ FCF | — | — | 75.94x | 22.32x | 153.73x |
Profitability & Efficiency
RGEN leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
RGEN delivers a 2.5% return on equity — every $100 of shareholder capital generates $2 in annual profit, vs $-43 for NUVL. AZTA carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to BRKR's 0.81x. On the Piotroski fundamental quality scale (0–9), RGEN scores 7/9 vs NUVL's 1/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -35.1% | -42.8% | +2.5% | -10.7% | -0.5% |
| ROA (TTM)Return on assets | -187.0% | -37.8% | +1.8% | -8.8% | -0.2% |
| ROICReturn on invested capital | -39.2% | -32.5% | +2.2% | -0.5% | +4.4% |
| ROCEReturn on capital employed | -25.7% | -34.4% | +2.2% | -0.6% | +5.0% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 1 | 7 | 6 | 4 |
| Debt / EquityFinancial leverage | 0.10x | — | 0.33x | 0.06x | 0.81x |
| Net DebtTotal debt minus cash | -$181M | -$262M | $124M | -$169M | $1.7B |
| Cash & Equiv.Liquid assets | $217M | $262M | $566M | $280M | $299M |
| Total DebtShort + long-term debt | $36M | $0 | $690M | $111M | $2.0B |
| Interest CoverageEBIT ÷ Interest expense | -10.92x | -26.85x | 2.64x | — | 1.14x |
Total Returns (Dividends Reinvested)
NUVL leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NUVL five years ago would be worth $54,613 today (with dividends reinvested), compared to $1,061 for MRVI. Over the past 12 months, MRVI leads with a +85.8% total return vs AZTA's -26.5%. The 3-year compound annual growth rate (CAGR) favors NUVL at 39.5% vs MRVI's -34.3% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +15.9% | +1.5% | -23.1% | -44.4% | -9.0% |
| 1-Year ReturnPast 12 months | +85.8% | +53.5% | -0.4% | -26.5% | +7.8% |
| 3-Year ReturnCumulative with dividends | -71.7% | +171.2% | -19.3% | -59.1% | -42.5% |
| 5-Year ReturnCumulative with dividends | -89.4% | +446.1% | -32.7% | -81.0% | -35.5% |
| 10-Year ReturnCumulative with dividends | -86.8% | +446.1% | +369.1% | +123.4% | +67.1% |
| CAGR (3Y)Annualised 3-year return | -34.3% | +39.5% | -6.9% | -25.8% | -16.9% |
Risk & Volatility
Evenly matched — MRVI and NUVL each lead in 1 of 2 comparable metrics.
Risk & Volatility
NUVL is the less volatile stock with a 1.09 beta — it tends to amplify market swings less than AZTA's 2.17 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRVI currently trades 96.0% from its 52-week high vs AZTA's 44.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.03x | 1.09x | 1.76x | 2.17x | 1.59x |
| 52-Week HighHighest price in past year | $4.11 | $113.02 | $175.77 | $41.73 | $56.22 |
| 52-Week LowLowest price in past year | $1.95 | $63.56 | $109.52 | $17.11 | $28.53 |
| % of 52W HighCurrent price vs 52-week peak | +96.0% | +90.6% | +71.9% | +44.5% | +77.8% |
| RSI (14)Momentum oscillator 0–100 | 67.7 | 52.9 | 55.1 | 31.1 | 64.8 |
| Avg Volume (50D)Average daily shares traded | 1.9M | 544K | 905K | 1.0M | 1.9M |
Analyst Outlook
MRVI leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: MRVI as "Buy", NUVL as "Buy", RGEN as "Buy", AZTA as "Buy", BRKR as "Buy". Consensus price targets imply 140.5% upside for AZTA (target: $45) vs 14.2% for MRVI (target: $5). BRKR is the only dividend payer here at 0.34% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $4.50 | $144.40 | $168.00 | $44.67 | $52.13 |
| # AnalystsCovering analysts | 14 | 14 | 23 | 12 | 32 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +0.3% |
| Dividend StreakConsecutive years of raises | 1 | — | — | 0 | 0 |
| Dividend / ShareAnnual DPS | — | — | — | — | $0.15 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | +0.2% |
RGEN leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). AZTA leads in 1 (Valuation Metrics). 1 tied.
MRVI vs NUVL vs RGEN vs AZTA vs BRKR: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is MRVI or NUVL or RGEN or AZTA or BRKR a better buy right now?
For growth investors, Repligen Corporation (RGEN) is the stronger pick with 16.
4% revenue growth year-over-year, versus -80. 8% for Maravai LifeSciences Holdings, Inc. (MRVI). Repligen Corporation (RGEN) offers the better valuation at 147. 0x trailing P/E (64. 3x forward), making it the more compelling value choice. Analysts rate Maravai LifeSciences Holdings, Inc. (MRVI) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — MRVI or NUVL or RGEN or AZTA or BRKR?
On forward P/E, Bruker Corporation is actually cheaper at 20.
7x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — MRVI or NUVL or RGEN or AZTA or BRKR?
Over the past 5 years, Nuvalent, Inc.
(NUVL) delivered a total return of +446. 1%, compared to -89. 4% for Maravai LifeSciences Holdings, Inc. (MRVI). Over 10 years, the gap is even starker: NUVL returned +446. 1% versus MRVI's -86. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — MRVI or NUVL or RGEN or AZTA or BRKR?
By beta (market sensitivity over 5 years), Nuvalent, Inc.
(NUVL) is the lower-risk stock at 1. 09β versus Azenta, Inc. 's 2. 17β — meaning AZTA is approximately 99% more volatile than NUVL relative to the S&P 500. On balance sheet safety, Azenta, Inc. (AZTA) carries a lower debt/equity ratio of 6% versus 81% for Bruker Corporation — giving it more financial flexibility in a downturn.
05Which is growing faster — MRVI or NUVL or RGEN or AZTA or BRKR?
By revenue growth (latest reported year), Repligen Corporation (RGEN) is pulling ahead at 16.
4% versus -80. 8% for Maravai LifeSciences Holdings, Inc. (MRVI). On earnings-per-share growth, the picture is similar: Repligen Corporation grew EPS 287. 0% year-over-year, compared to -119. 7% for Bruker Corporation. Over a 3-year CAGR, BRKR leads at 10. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — MRVI or NUVL or RGEN or AZTA or BRKR?
Repligen Corporation (RGEN) is the more profitable company, earning 6.
6% net margin versus -262. 2% for Maravai LifeSciences Holdings, Inc. — meaning it keeps 6. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RGEN leads at 8. 1% versus -431. 7% for MRVI. At the gross margin level — before operating expenses — RGEN leads at 47. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is MRVI or NUVL or RGEN or AZTA or BRKR more undervalued right now?
On forward earnings alone, Bruker Corporation (BRKR) trades at 20.
7x forward P/E versus 64. 3x for Repligen Corporation — 43. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for AZTA: 140. 5% to $44. 67.
08Which pays a better dividend — MRVI or NUVL or RGEN or AZTA or BRKR?
In this comparison, BRKR (0.
3% yield) pays a dividend. MRVI, NUVL, RGEN, AZTA do not pay a meaningful dividend and should not be held primarily for income.
09Is MRVI or NUVL or RGEN or AZTA or BRKR better for a retirement portfolio?
For long-horizon retirement investors, Nuvalent, Inc.
(NUVL) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 09), +446. 1% 10Y return). Maravai LifeSciences Holdings, Inc. (MRVI) carries a higher beta of 2. 03 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (NUVL: +446. 1%, MRVI: -86. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between MRVI and NUVL and RGEN and AZTA and BRKR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: MRVI is a small-cap quality compounder stock; NUVL is a small-cap quality compounder stock; RGEN is a small-cap high-growth stock; AZTA is a small-cap quality compounder stock; BRKR is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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