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MYNZ vs GKOS vs HOLX vs EXAS vs GH

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MYNZ
Mainz Biomed B.V.

Medical - Diagnostics & Research

HealthcareNASDAQ • DE
Market Cap$678K
5Y Perf.-99.8%
GKOS
Glaukos Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$7.81B
5Y Perf.+179.8%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+0.8%
EXAS
Exact Sciences Corporation

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$20.02B
5Y Perf.+21.1%
GH
Guardant Health, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$12.55B
5Y Perf.-10.7%

MYNZ vs GKOS vs HOLX vs EXAS vs GH — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MYNZ logoMYNZ
GKOS logoGKOS
HOLX logoHOLX
EXAS logoEXAS
GH logoGH
IndustryMedical - Diagnostics & ResearchMedical - DevicesMedical - Instruments & SuppliesMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$678K$7.81B$16.97B$20.02B$12.55B
Revenue (TTM)$2M$551M$4.13B$3.25B$1.08B
Net Income (TTM)$-40M$-189M$544M$-208M$-433M
Gross Margin55.5%78.1%52.8%69.7%64.9%
Operating Margin-27.3%-15.6%17.5%-6.4%-41.4%
Forward P/E17.2x582.8x
Total Debt$3M$140M$2.63B$2.52B$1.68B
Cash & Equiv.$6M$91M$1.96B$956M$378M

MYNZ vs GKOS vs HOLX vs EXAS vs GHLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MYNZ
GKOS
HOLX
EXAS
GH
StockNov 21Mar 26Return
Mainz Biomed B.V. (MYNZ)1000.2-99.8%
Glaukos Corporation (GKOS)100279.8+179.8%
Hologic, Inc. (HOLX)100100.8+0.8%
Exact Sciences Corp… (EXAS)100121.1+21.1%
Guardant Health, In… (GH)10089.3-10.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: MYNZ vs GKOS vs HOLX vs EXAS vs GH

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HOLX leads in 3 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Guardant Health, Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. EXAS also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
MYNZ
Mainz Biomed B.V.
The Healthcare Pick

MYNZ lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
GKOS
Glaukos Corporation
The Long-Run Compounder

GKOS is the clearest fit if your priority is long-term compounding.

  • 454.5% 10Y total return vs EXAS's 16.7%
Best for: long-term compounding
HOLX
Hologic, Inc.
The Defensive Pick

HOLX carries the broadest edge in this set and is the clearest fit for sleep-well-at-night.

  • Lower volatility, beta 0.45, Low D/E 52.0%, current ratio 3.75x
  • Better valuation composite
  • 13.2% margin vs MYNZ's -24.9%
  • 6.1% ROA vs MYNZ's -302.9%, ROIC 9.4% vs -419.7%
Best for: sleep-well-at-night
EXAS
Exact Sciences Corporation
The Income Pick

EXAS ranks third and is worth considering specifically for income & stability.

  • beta 0.05
  • Beta 0.05 vs MYNZ's 1.62
Best for: income & stability
GH
Guardant Health, Inc.
The Growth Play

GH is the #2 pick in this set and the best alternative if growth exposure and defensive is your priority.

  • Rev growth 32.9%, EPS growth 6.7%, 3Y rev CAGR 29.8%
  • Beta 0.86, current ratio 4.84x
  • 32.9% revenue growth vs MYNZ's -0.2%
  • +129.6% vs MYNZ's -72.5%
Best for: growth exposure and defensive
See the full category breakdown
CategoryWinnerWhy
GrowthGH logoGH32.9% revenue growth vs MYNZ's -0.2%
ValueHOLX logoHOLXBetter valuation composite
Quality / MarginsHOLX logoHOLX13.2% margin vs MYNZ's -24.9%
Stability / SafetyEXAS logoEXASBeta 0.05 vs MYNZ's 1.62
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)GH logoGH+129.6% vs MYNZ's -72.5%
Efficiency (ROA)HOLX logoHOLX6.1% ROA vs MYNZ's -302.9%, ROIC 9.4% vs -419.7%

MYNZ vs GKOS vs HOLX vs EXAS vs GH — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MYNZMainz Biomed B.V.

Segment breakdown not available.

GKOSGlaukos Corporation
FY 2019
Glaucoma
97.5%$231M
Corneal Health
2.5%$6M
HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
EXASExact Sciences Corporation
FY 2025
Screening
77.9%$2.5B
Precision Oncology
22.1%$717M
GHGuardant Health, Inc.
FY 2025
Oncology
69.6%$684M
Biopharma & Data
21.4%$210M
Screening
8.1%$80M
Licensing & Other
0.9%$9M

MYNZ vs GKOS vs HOLX vs EXAS vs GH — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHOLXLAGGINGEXAS

Income & Cash Flow (Last 12 Months)

HOLX leads this category, winning 3 of 6 comparable metrics.

HOLX is the larger business by revenue, generating $4.1B annually — 2564.6x MYNZ's $2M. HOLX is the more profitable business, keeping 13.2% of every revenue dollar as net income compared to MYNZ's -24.9%. On growth, MYNZ holds the edge at +73.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricMYNZ logoMYNZMainz Biomed B.V.GKOS logoGKOSGlaukos Corporati…HOLX logoHOLXHologic, Inc.EXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …
RevenueTrailing 12 months$2M$551M$4.1B$3.2B$1.1B
EBITDAEarnings before interest/tax-$42M-$40M$974M-$41M-$418M
Net IncomeAfter-tax profit-$40M-$189M$544M-$208M-$433M
Free Cash FlowCash after capex-$28M-$18M$1000M$357M-$225M
Gross MarginGross profit ÷ Revenue+55.5%+78.1%+52.8%+69.7%+64.9%
Operating MarginEBIT ÷ Revenue-27.3%-15.6%+17.5%-6.4%-41.4%
Net MarginNet income ÷ Revenue-24.9%-34.3%+13.2%-6.4%-40.1%
FCF MarginFCF ÷ Revenue-17.1%-3.4%+24.2%+11.0%-20.8%
Rev. Growth (YoY)Latest quarter vs prior year+73.8%+41.2%+2.5%+23.1%+48.3%
EPS Growth (YoY)Latest quarter vs prior year+34.3%-6.3%-9.2%+90.4%-10.4%
HOLX leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — MYNZ and HOLX each lead in 2 of 5 comparable metrics.
MetricMYNZ logoMYNZMainz Biomed B.V.GKOS logoGKOSGlaukos Corporati…HOLX logoHOLXHologic, Inc.EXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …
Market CapShares × price$677,764$7.8B$17.0B$20.0B$12.6B
Enterprise ValueMkt cap + debt − cash-$2M$7.9B$17.6B$21.6B$13.9B
Trailing P/EPrice ÷ TTM EPS-0.03x-40.71x30.53x-95.37x-28.83x
Forward P/EPrice ÷ next-FY EPS est.17.21x582.83x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple17.39x
Price / SalesMarket cap ÷ Revenue0.76x15.40x4.14x6.16x12.78x
Price / BookPrice ÷ Book value/share0.11x11.64x3.43x8.24x
Price / FCFMarket cap ÷ FCF18.44x56.10x
Evenly matched — MYNZ and HOLX each lead in 2 of 5 comparable metrics.

Profitability & Efficiency

HOLX leads this category, winning 6 of 9 comparable metrics.

HOLX delivers a 11.0% return on equity — every $100 of shareholder capital generates $11 in annual profit, vs $-7 for MYNZ. GKOS carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to EXAS's 1.05x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs GKOS's 3/9, reflecting strong financial health.

MetricMYNZ logoMYNZMainz Biomed B.V.GKOS logoGKOSGlaukos Corporati…HOLX logoHOLXHologic, Inc.EXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …
ROE (TTM)Return on equity-6.6%-26.5%+11.0%-8.7%
ROA (TTM)Return on assets-3.0%-20.1%+6.1%-3.5%-26.5%
ROICReturn on invested capital-4.2%-9.2%+9.4%-3.6%-34.9%
ROCEReturn on capital employed-2.8%-10.3%+8.8%-4.0%-29.4%
Piotroski ScoreFundamental quality 0–963775
Debt / EquityFinancial leverage0.54x0.21x0.52x1.05x
Net DebtTotal debt minus cash-$3M$49M$667M$1.6B$1.3B
Cash & Equiv.Liquid assets$6M$91M$2.0B$956M$378M
Total DebtShort + long-term debt$3M$140M$2.6B$2.5B$1.7B
Interest CoverageEBIT ÷ Interest expense-18.32x-18.69x8.00x-5.47x-250.66x
HOLX leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GH leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in GKOS five years ago would be worth $17,474 today (with dividends reinvested), compared to $18 for MYNZ. Over the past 12 months, GH leads with a +129.6% total return vs MYNZ's -72.5%. The 3-year compound annual growth rate (CAGR) favors GH at 59.6% vs MYNZ's -84.9% — a key indicator of consistent wealth creation.

MetricMYNZ logoMYNZMainz Biomed B.V.GKOS logoGKOSGlaukos Corporati…HOLX logoHOLXHologic, Inc.EXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …
YTD ReturnYear-to-date-39.7%+20.6%+1.9%+3.1%-5.9%
1-Year ReturnPast 12 months-72.5%+47.5%+35.3%+97.7%+129.6%
3-Year ReturnCumulative with dividends-99.7%+127.6%-8.5%+53.0%+306.7%
5-Year ReturnCumulative with dividends-99.8%+74.7%+16.8%+6.1%-21.4%
10-Year ReturnCumulative with dividends-99.8%+454.5%+124.3%+1669.1%+197.2%
CAGR (3Y)Annualised 3-year return-84.9%+31.5%-2.9%+15.2%+59.6%
GH leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — HOLX and EXAS each lead in 1 of 2 comparable metrics.

EXAS is the less volatile stock with a 0.05 beta — it tends to amplify market swings less than MYNZ's 1.62 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs MYNZ's 26.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMYNZ logoMYNZMainz Biomed B.V.GKOS logoGKOSGlaukos Corporati…HOLX logoHOLXHologic, Inc.EXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …
Beta (5Y)Sensitivity to S&P 5001.62x1.16x0.45x0.05x0.86x
52-Week HighHighest price in past year$2.64$146.75$76.04$104.98$120.74
52-Week LowLowest price in past year$0.55$73.16$53.62$38.81$36.36
% of 52W HighCurrent price vs 52-week peak+26.5%+91.0%+100.0%+99.9%+79.3%
RSI (14)Momentum oscillator 0–10040.161.569.176.455.9
Avg Volume (50D)Average daily shares traded603K674K10.3M4.3M1.9M
Evenly matched — HOLX and EXAS each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: GKOS as "Buy", HOLX as "Hold", EXAS as "Buy", GH as "Buy". Consensus price targets imply 39.1% upside for GH (target: $133) vs 0.1% for EXAS (target: $105).

MetricMYNZ logoMYNZMainz Biomed B.V.GKOS logoGKOSGlaukos Corporati…HOLX logoHOLXHologic, Inc.EXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …
Analyst RatingConsensus buy/hold/sellBuyHoldBuyBuy
Price TargetConsensus 12-month target$146.67$79.00$105.00$133.14
# AnalystsCovering analysts24424130
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+4.4%+0.1%+0.1%
Insufficient data to determine a leader in this category.
Key Takeaway

HOLX leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). GH leads in 1 (Total Returns). 2 tied.

Best OverallHologic, Inc. (HOLX)Leads 2 of 6 categories
Loading custom metrics...

MYNZ vs GKOS vs HOLX vs EXAS vs GH: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is MYNZ or GKOS or HOLX or EXAS or GH a better buy right now?

For growth investors, Guardant Health, Inc.

(GH) is the stronger pick with 32. 9% revenue growth year-over-year, versus -0. 2% for Mainz Biomed B. V. (MYNZ). Hologic, Inc. (HOLX) offers the better valuation at 30. 5x trailing P/E (17. 2x forward), making it the more compelling value choice. Analysts rate Glaukos Corporation (GKOS) a "Buy" — based on 24 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MYNZ or GKOS or HOLX or EXAS or GH?

On forward P/E, Hologic, Inc.

is actually cheaper at 17. 2x.

03

Which is the better long-term investment — MYNZ or GKOS or HOLX or EXAS or GH?

Over the past 5 years, Glaukos Corporation (GKOS) delivered a total return of +74.

7%, compared to -99. 8% for Mainz Biomed B. V. (MYNZ). Over 10 years, the gap is even starker: EXAS returned +1669% versus MYNZ's -99. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MYNZ or GKOS or HOLX or EXAS or GH?

By beta (market sensitivity over 5 years), Exact Sciences Corporation (EXAS) is the lower-risk stock at 0.

05β versus Mainz Biomed B. V. 's 1. 62β — meaning MYNZ is approximately 2976% more volatile than EXAS relative to the S&P 500. On balance sheet safety, Glaukos Corporation (GKOS) carries a lower debt/equity ratio of 21% versus 105% for Exact Sciences Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — MYNZ or GKOS or HOLX or EXAS or GH?

By revenue growth (latest reported year), Guardant Health, Inc.

(GH) is pulling ahead at 32. 9% versus -0. 2% for Mainz Biomed B. V. (MYNZ). On earnings-per-share growth, the picture is similar: Exact Sciences Corporation grew EPS 80. 3% year-over-year, compared to -1280. 2% for Mainz Biomed B. V.. Over a 3-year CAGR, GH leads at 29. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MYNZ or GKOS or HOLX or EXAS or GH?

Hologic, Inc.

(HOLX) is the more profitable company, earning 13. 8% net margin versus -24. 2% for Mainz Biomed B. V. — meaning it keeps 13. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HOLX leads at 17. 4% versus -20. 9% for MYNZ. At the gross margin level — before operating expenses — GKOS leads at 77. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MYNZ or GKOS or HOLX or EXAS or GH more undervalued right now?

On forward earnings alone, Hologic, Inc.

(HOLX) trades at 17. 2x forward P/E versus 582. 8x for Exact Sciences Corporation — 565. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for GH: 39. 1% to $133. 14.

08

Which pays a better dividend — MYNZ or GKOS or HOLX or EXAS or GH?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is MYNZ or GKOS or HOLX or EXAS or GH better for a retirement portfolio?

For long-horizon retirement investors, Exact Sciences Corporation (EXAS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

05), +1669% 10Y return). Mainz Biomed B. V. (MYNZ) carries a higher beta of 1. 62 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (EXAS: +1669%, MYNZ: -99. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MYNZ and GKOS and HOLX and EXAS and GH?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: MYNZ is a small-cap quality compounder stock; GKOS is a small-cap high-growth stock; HOLX is a mid-cap quality compounder stock; EXAS is a mid-cap high-growth stock; GH is a mid-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
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EXAS

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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 24%
  • Gross Margin > 38%
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