Medical - Pharmaceuticals
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Side-by-side financial analysisStock Comparison
NEUP vs LLY vs BIIB vs IQV vs CRL
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Medical - Diagnostics & Research
Medical - Diagnostics & Research
NEUP vs LLY vs BIIB vs IQV vs CRL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Pharmaceuticals | Drug Manufacturers - General | Drug Manufacturers - General | Medical - Diagnostics & Research | Medical - Diagnostics & Research |
| Market Cap | $23M | $1.04T | $29.02B | $28.47B | $8.91B |
| Revenue (TTM) | $-10M | $72.25B | $9.86B | $16.63B | $4.03B |
| Net Income (TTM) | $-28M | $25.27B | $1.37B | $1.39B | $-185M |
| Gross Margin | 100.0% | 83.5% | 69.8% | 26.1% | 31.9% |
| Operating Margin | -7.2% | 45.9% | 15.6% | 13.9% | 11.8% |
| Forward P/E | — | 30.0x | 13.5x | 13.1x | 16.7x |
| Total Debt | $226K | $42.50B | $6.95B | $16.17B | $3.07B |
| Cash & Equiv. | $22M | $7.16B | $3.01B | $1.98B | $214M |
NEUP vs LLY vs BIIB vs IQV vs CRL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Dec 21 | Jun 26 | Return |
|---|---|---|---|
| Neuphoria Therapeut… (NEUP) | 100 | 2.9 | -97.1% |
| Eli Lilly and Compa… (LLY) | 100 | 397.6 | +297.6% |
| Biogen Inc. (BIIB) | 100 | 81.9 | -18.1% |
| IQVIA Holdings Inc. (IQV) | 100 | 59.5 | -40.5% |
| Charles River Labor… (CRL) | 100 | 49.1 | -50.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: NEUP vs LLY vs BIIB vs IQV vs CRL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
NEUP lags the leaders in this set but could rank higher in a more targeted comparison.
LLY carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 11 yrs, beta 0.52, yield 0.5%
- Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
- 14.5% 10Y total return vs IQV's 163.4%
- 44.7% revenue growth vs NEUP's -140.1%
BIIB is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 0.34, Low D/E 38.1%, current ratio 2.68x
- Beta 0.34, current ratio 2.68x
- Beta 0.34 vs NEUP's 1.38
- +55.4% vs NEUP's -34.9%
IQV ranks third and is worth considering specifically for valuation efficiency.
- PEG 0.32 vs LLY's 1.04
- Lower P/E (13.1x vs 16.7x)
Among these 5 stocks, CRL doesn't own a clear edge in any measured category.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 44.7% revenue growth vs NEUP's -140.1% | |
| Value | Lower P/E (13.1x vs 16.7x) | |
| Quality / Margins | 35.0% margin vs CRL's -4.6% | |
| Stability / Safety | Beta 0.34 vs NEUP's 1.38 | |
| Dividends | 0.5% yield; 11-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +55.4% vs NEUP's -34.9% | |
| Efficiency (ROA) | 22.7% ROA vs NEUP's -77.5%, ROIC 41.8% vs -13.4% |
NEUP vs LLY vs BIIB vs IQV vs CRL — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
NEUP vs LLY vs BIIB vs IQV vs CRL — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
LLY leads in 4 of 6 categories
NEUP leads 1 • BIIB leads 1 • IQV leads 0 • CRL leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
LLY leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
LLY and NEUP operate at a comparable scale, with $72.2B and -$10M in trailing revenue. LLY is the more profitable business, keeping 35.0% of every revenue dollar as net income compared to CRL's -4.6%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | -$10M | $72.2B | $9.9B | $16.6B | $4.0B |
| EBITDAEarnings before interest/tax | -$25M | $34.7B | $2.4B | $3.5B | $824M |
| Net IncomeAfter-tax profit | -$28M | $25.3B | $1.4B | $1.4B | -$185M |
| Free Cash FlowCash after capex | $59M | $13.6B | $2.6B | $2.7B | $391M |
| Gross MarginGross profit ÷ Revenue | +100.0% | +83.5% | +69.8% | +26.1% | +31.9% |
| Operating MarginEBIT ÷ Revenue | -7.2% | +45.9% | +15.6% | +13.9% | +11.8% |
| Net MarginNet income ÷ Revenue | -2.4% | +35.0% | +13.9% | +8.3% | -4.6% |
| FCF MarginFCF ÷ Revenue | +4.9% | +18.8% | +26.6% | +16.1% | +9.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | +55.5% | +1.9% | +8.4% | +1.2% |
| EPS Growth (YoY)Latest quarter vs prior year | -101.4% | +169.9% | +31.1% | +15.0% | -160.0% |
Valuation Metrics
NEUP leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 21.4x trailing earnings, IQV trades at a 55% valuation discount to LLY's 47.8x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.53x vs LLY's 1.66x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $23M | $1.04T | $29.0B | $28.5B | $8.9B |
| Enterprise ValueMkt cap + debt − cash | $2M | $1.07T | $33.0B | $42.7B | $11.8B |
| Trailing P/EPrice ÷ TTM EPS | -18.74x | 47.85x | 22.26x | 21.40x | -63.57x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 30.00x | 13.51x | 13.09x | 16.68x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.66x | — | 0.53x | — |
| EV / EBITDAEnterprise value multiple | — | 34.32x | 11.72x | 12.44x | 12.91x |
| Price / SalesMarket cap ÷ Revenue | 1.49x | 15.92x | 2.96x | 1.75x | 2.22x |
| Price / BookPrice ÷ Book value/share | 0.24x | 37.16x | 1.58x | 4.39x | 2.86x |
| Price / FCFMarket cap ÷ FCF | 0.30x | 115.64x | 14.15x | 13.88x | 17.19x |
Profitability & Efficiency
LLY leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
LLY delivers a 101.2% return on equity — every $100 of shareholder capital generates $101 in annual profit, vs $-110 for NEUP. NEUP carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), NEUP scores 8/9 vs CRL's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -109.7% | +101.2% | +7.5% | +22.1% | -5.7% |
| ROA (TTM)Return on assets | -77.5% | +22.7% | +4.7% | +4.7% | -2.5% |
| ROICReturn on invested capital | -13.4% | +41.8% | +6.5% | +8.7% | +6.3% |
| ROCEReturn on capital employed | -3.7% | +46.6% | +7.7% | +11.0% | +8.1% |
| Piotroski ScoreFundamental quality 0–9 | 8 | 8 | 5 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.01x | 1.60x | 0.38x | 2.44x | 0.95x |
| Net DebtTotal debt minus cash | -$21M | $35.3B | $3.9B | $14.2B | $2.9B |
| Cash & Equiv.Liquid assets | $22M | $7.2B | $3.0B | $2.0B | $214M |
| Total DebtShort + long-term debt | $226,487 | $42.5B | $6.9B | $16.2B | $3.1B |
| Interest CoverageEBIT ÷ Interest expense | — | 35.68x | 6.91x | 3.10x | 4.29x |
Total Returns (Dividends Reinvested)
LLY leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LLY five years ago would be worth $51,381 today (with dividends reinvested), compared to $244 for NEUP. Over the past 12 months, BIIB leads with a +55.4% total return vs NEUP's -34.9%. The 3-year compound annual growth rate (CAGR) favors LLY at 35.1% vs NEUP's -47.9% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +12.8% | +2.0% | +10.5% | -25.6% | -8.6% |
| 1-Year ReturnPast 12 months | -34.9% | +40.7% | +55.4% | +8.5% | +27.3% |
| 3-Year ReturnCumulative with dividends | -85.8% | +146.7% | -33.1% | -21.9% | -11.7% |
| 5-Year ReturnCumulative with dividends | -97.6% | +413.8% | -49.4% | -30.0% | -47.7% |
| 10-Year ReturnCumulative with dividends | -97.6% | +1449.6% | -17.2% | +163.4% | +123.2% |
| CAGR (3Y)Annualised 3-year return | -47.9% | +35.1% | -12.5% | -7.9% | -4.1% |
Risk & Volatility
BIIB leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
BIIB is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than NEUP's 1.38 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BIIB currently trades 95.4% from its 52-week high vs NEUP's 20.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.38x | 0.52x | 0.34x | 1.12x | 1.35x |
| 52-Week HighHighest price in past year | $21.40 | $1182.73 | $205.97 | $247.05 | $228.88 |
| 52-Week LowLowest price in past year | $3.65 | $623.78 | $121.05 | $153.01 | $143.06 |
| % of 52W HighCurrent price vs 52-week peak | +20.1% | +92.8% | +95.4% | +67.9% | +80.8% |
| RSI (14)Momentum oscillator 0–100 | 36.3 | 57.2 | 55.2 | 42.4 | 54.2 |
| Avg Volume (50D)Average daily shares traded | 48K | 2.6M | 1.0M | 1.5M | 763K |
Analyst Outlook
LLY leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: LLY as "Buy", BIIB as "Buy", IQV as "Buy", CRL as "Buy". Consensus price targets imply 30.8% upside for IQV (target: $219) vs 11.1% for BIIB (target: $218). LLY is the only dividend payer here at 0.55% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $1271.24 | $218.32 | $219.44 | $214.14 |
| # AnalystsCovering analysts | — | 45 | 48 | 44 | 37 |
| Dividend YieldAnnual dividend ÷ price | — | +0.5% | — | — | — |
| Dividend StreakConsecutive years of raises | — | 11 | 0 | 2 | 1 |
| Dividend / ShareAnnual DPS | — | $6.00 | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.4% | 0.0% | +4.4% | +4.0% |
LLY leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NEUP leads in 1 (Valuation Metrics).
NEUP vs LLY vs BIIB vs IQV vs CRL: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is NEUP or LLY or BIIB or IQV or CRL a better buy right now?
For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.
7% revenue growth year-over-year, versus -0. 9% for Charles River Laboratories International, Inc. (CRL). IQVIA Holdings Inc. (IQV) offers the better valuation at 21. 4x trailing P/E (13. 1x forward), making it the more compelling value choice. Analysts rate Eli Lilly and Company (LLY) a "Buy" — based on 45 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — NEUP or LLY or BIIB or IQV or CRL?
On trailing P/E, IQVIA Holdings Inc.
(IQV) is the cheapest at 21. 4x versus Eli Lilly and Company at 47. 8x. On forward P/E, IQVIA Holdings Inc. is actually cheaper at 13. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 32x versus Eli Lilly and Company's 1. 04x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — NEUP or LLY or BIIB or IQV or CRL?
Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +413.
8%, compared to -97. 6% for Neuphoria Therapeutics Inc. (NEUP). Over 10 years, the gap is even starker: LLY returned +1450% versus NEUP's -97. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — NEUP or LLY or BIIB or IQV or CRL?
By beta (market sensitivity over 5 years), Biogen Inc.
(BIIB) is the lower-risk stock at 0. 34β versus Neuphoria Therapeutics Inc. 's 1. 38β — meaning NEUP is approximately 302% more volatile than BIIB relative to the S&P 500. On balance sheet safety, Neuphoria Therapeutics Inc. (NEUP) carries a lower debt/equity ratio of 1% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — NEUP or LLY or BIIB or IQV or CRL?
By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.
7% versus -0. 9% for Charles River Laboratories International, Inc. (CRL). On earnings-per-share growth, the picture is similar: Eli Lilly and Company grew EPS 96. 0% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, NEUP leads at 290. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — NEUP or LLY or BIIB or IQV or CRL?
Eli Lilly and Company (LLY) is the more profitable company, earning 31.
7% net margin versus -3. 6% for Charles River Laboratories International, Inc. — meaning it keeps 31. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus -7. 2% for NEUP. At the gross margin level — before operating expenses — NEUP leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is NEUP or LLY or BIIB or IQV or CRL more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 32x versus Eli Lilly and Company's 1. 04x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, IQVIA Holdings Inc. (IQV) trades at 13. 1x forward P/E versus 30. 0x for Eli Lilly and Company — 16. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for IQV: 30. 8% to $219. 44.
08Which pays a better dividend — NEUP or LLY or BIIB or IQV or CRL?
In this comparison, LLY (0.
5% yield) pays a dividend. NEUP, BIIB, IQV, CRL do not pay a meaningful dividend and should not be held primarily for income.
09Is NEUP or LLY or BIIB or IQV or CRL better for a retirement portfolio?
For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
52), 0. 5% yield, +1450% 10Y return). Both have compounded well over 10 years (LLY: +1450%, NEUP: -97. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between NEUP and LLY and BIIB and IQV and CRL?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: NEUP is a small-cap quality compounder stock; LLY is a mega-cap high-growth stock; BIIB is a mid-cap quality compounder stock; IQV is a mid-cap quality compounder stock; CRL is a small-cap quality compounder stock. LLY pays a dividend while NEUP, BIIB, IQV, CRL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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