Biotechnology
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OABI vs HALO vs RCUS vs REGN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
OABI vs HALO vs RCUS vs REGN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $167M | $7.68B | $2.50B | $73.68B |
| Revenue (TTM) | $29M | $1.40B | $236M | $14.92B |
| Net Income (TTM) | $-54M | $317M | $-369M | $4.42B |
| Gross Margin | 82.8% | 81.9% | 90.7% | 84.5% |
| Operating Margin | -173.0% | 58.4% | -168.6% | 24.3% |
| Forward P/E | — | 8.1x | — | 15.3x |
| Total Debt | $20M | $0.00 | $99M | $2.71B |
| Cash & Equiv. | $26M | $134M | $222M | $3.12B |
OABI vs HALO vs RCUS vs REGN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Sep 21 | May 26 | Return |
|---|---|---|---|
| OmniAb, Inc. (OABI) | 100 | 15.1 | -84.9% |
| Halozyme Therapeuti… (HALO) | 100 | 160.3 | +60.3% |
| Arcus Biosciences, … (RCUS) | 100 | 71.1 | -28.9% |
| Regeneron Pharmaceu… (REGN) | 100 | 117.2 | +17.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: OABI vs HALO vs RCUS vs REGN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
OABI lags the leaders in this set but could rank higher in a more targeted comparison.
HALO carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- beta 0.56
- 5.7% 10Y total return vs REGN's 90.0%
- Lower volatility, beta 0.56, current ratio 4.66x
- PEG 0.35 vs REGN's 2.43
RCUS is the clearest fit if your priority is momentum.
- +209.6% vs HALO's -7.1%
REGN is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 1.0%, EPS growth 8.2%, 3Y rev CAGR 5.6%
- 29.6% margin vs OABI's -187.6%
- 0.5% yield; 1-year raise streak; the other 3 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 37.6% revenue growth vs OABI's -29.3% | |
| Value | Lower P/E (8.1x vs 15.3x), PEG 0.35 vs 2.43 | |
| Quality / Margins | 29.6% margin vs OABI's -187.6% | |
| Stability / Safety | Beta 0.56 vs RCUS's 1.95 | |
| Dividends | 0.5% yield; 1-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +209.6% vs HALO's -7.1% | |
| Efficiency (ROA) | 12.5% ROA vs RCUS's -35.3%, ROIC 73.4% vs -64.1% |
OABI vs HALO vs RCUS vs REGN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
OABI vs HALO vs RCUS vs REGN — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 3 of 6 categories
OABI leads 0 • RCUS leads 0 • REGN leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — OABI and HALO each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
REGN is the larger business by revenue, generating $14.9B annually — 515.6x OABI's $29M. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to OABI's -187.6%. On growth, OABI holds the edge at +2.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $29M | $1.4B | $236M | $14.9B |
| EBITDAEarnings before interest/tax | -$33M | $945M | -$391M | $4.2B |
| Net IncomeAfter-tax profit | -$54M | $317M | -$369M | $4.4B |
| Free Cash FlowCash after capex | -$26M | $645M | -$489M | $4.2B |
| Gross MarginGross profit ÷ Revenue | +82.8% | +81.9% | +90.7% | +84.5% |
| Operating MarginEBIT ÷ Revenue | -173.0% | +58.4% | -168.6% | +24.3% |
| Net MarginNet income ÷ Revenue | -187.6% | +22.7% | -156.4% | +29.6% |
| FCF MarginFCF ÷ Revenue | -89.9% | +46.2% | -2.1% | +27.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | +2.5% | +51.6% | -39.3% | +19.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +64.7% | -2.1% | +10.5% | -7.2% |
Valuation Metrics
HALO leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 17.1x trailing earnings, REGN trades at a 33% valuation discount to HALO's 25.5x P/E. Adjusting for growth (PEG ratio), HALO offers better value at 1.11x vs REGN's 2.70x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $167M | $7.7B | $2.5B | $73.7B |
| Enterprise ValueMkt cap + debt − cash | $162M | $7.5B | $2.4B | $73.3B |
| Trailing P/EPrice ÷ TTM EPS | -2.58x | 25.46x | -7.54x | 17.09x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 8.09x | — | 15.35x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.11x | — | 2.70x |
| EV / EBITDAEnterprise value multiple | — | 8.34x | — | 17.78x |
| Price / SalesMarket cap ÷ Revenue | 8.96x | 5.50x | 10.11x | 5.14x |
| Price / BookPrice ÷ Book value/share | 0.63x | 165.47x | 4.22x | 2.46x |
| Price / FCFMarket cap ÷ FCF | — | 11.91x | — | 18.06x |
Profitability & Efficiency
HALO leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-69 for RCUS. OABI carries lower financial leverage with a 0.08x debt-to-equity ratio, signaling a more conservative balance sheet compared to RCUS's 0.16x. On the Piotroski fundamental quality scale (0–9), HALO scores 5/9 vs RCUS's 0/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -20.3% | +6.5% | -69.0% | +14.3% |
| ROA (TTM)Return on assets | -18.1% | +12.5% | -35.3% | +11.1% |
| ROICReturn on invested capital | -19.7% | +73.4% | -64.1% | +8.9% |
| ROCEReturn on capital employed | -24.0% | +38.2% | -42.1% | +10.2% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 5 | 0 | 5 |
| Debt / EquityFinancial leverage | 0.08x | — | 0.16x | 0.09x |
| Net DebtTotal debt minus cash | -$5M | -$134M | -$123M | -$412M |
| Cash & Equiv.Liquid assets | $26M | $134M | $222M | $3.1B |
| Total DebtShort + long-term debt | $20M | $0 | $99M | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | — | 46.08x | -13.38x | 108.44x |
Total Returns (Dividends Reinvested)
HALO leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in REGN five years ago would be worth $14,365 today (with dividends reinvested), compared to $1,506 for OABI. Over the past 12 months, RCUS leads with a +209.6% total return vs HALO's -7.1%. The 3-year compound annual growth rate (CAGR) favors HALO at 29.1% vs OABI's -24.8% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -21.8% | -7.3% | +6.5% | -8.5% |
| 1-Year ReturnPast 12 months | -3.9% | -7.1% | +209.6% | +27.1% |
| 3-Year ReturnCumulative with dividends | -57.4% | +115.3% | +24.9% | -5.1% |
| 5-Year ReturnCumulative with dividends | -84.9% | +37.0% | -18.6% | +43.6% |
| 10-Year ReturnCumulative with dividends | -84.9% | +570.7% | +45.9% | +90.0% |
| CAGR (3Y)Annualised 3-year return | -24.8% | +29.1% | +7.7% | -1.7% |
Risk & Volatility
Evenly matched — HALO and REGN each lead in 1 of 2 comparable metrics.
Risk & Volatility
HALO is the less volatile stock with a 0.56 beta — it tends to amplify market swings less than RCUS's 1.95 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. REGN currently trades 86.4% from its 52-week high vs OABI's 63.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.51x | 0.56x | 1.95x | 0.81x |
| 52-Week HighHighest price in past year | $2.30 | $82.22 | $28.72 | $821.11 |
| 52-Week LowLowest price in past year | $1.22 | $47.50 | $7.06 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +63.9% | +79.3% | +86.3% | +86.4% |
| RSI (14)Momentum oscillator 0–100 | 42.5 | 52.4 | 60.5 | 44.9 |
| Avg Volume (50D)Average daily shares traded | 428K | 1.4M | 1.2M | 631K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: OABI as "Buy", HALO as "Buy", RCUS as "Buy", REGN as "Buy". Consensus price targets imply 172.1% upside for OABI (target: $4) vs 20.2% for HALO (target: $78). REGN is the only dividend payer here at 0.48% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $4.00 | $78.33 | $30.00 | $865.68 |
| # AnalystsCovering analysts | 9 | 27 | 18 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +0.5% |
| Dividend StreakConsecutive years of raises | — | — | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +4.5% | 0.0% | +5.4% |
HALO leads in 3 of 6 categories — strongest in Valuation Metrics and Profitability & Efficiency. 2 categories are tied.
OABI vs HALO vs RCUS vs REGN: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is OABI or HALO or RCUS or REGN a better buy right now?
For growth investors, Halozyme Therapeutics, Inc.
(HALO) is the stronger pick with 37. 6% revenue growth year-over-year, versus -29. 3% for OmniAb, Inc. (OABI). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 1x trailing P/E (15. 3x forward), making it the more compelling value choice. Analysts rate OmniAb, Inc. (OABI) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — OABI or HALO or RCUS or REGN?
On trailing P/E, Regeneron Pharmaceuticals, Inc.
(REGN) is the cheapest at 17. 1x versus Halozyme Therapeutics, Inc. at 25. 5x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 1x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Halozyme Therapeutics, Inc. wins at 0. 35x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — OABI or HALO or RCUS or REGN?
Over the past 5 years, Regeneron Pharmaceuticals, Inc.
(REGN) delivered a total return of +43. 6%, compared to -84. 9% for OmniAb, Inc. (OABI). Over 10 years, the gap is even starker: HALO returned +570. 7% versus OABI's -84. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — OABI or HALO or RCUS or REGN?
By beta (market sensitivity over 5 years), Halozyme Therapeutics, Inc.
(HALO) is the lower-risk stock at 0. 56β versus Arcus Biosciences, Inc. 's 1. 95β — meaning RCUS is approximately 250% more volatile than HALO relative to the S&P 500. On balance sheet safety, OmniAb, Inc. (OABI) carries a lower debt/equity ratio of 8% versus 16% for Arcus Biosciences, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — OABI or HALO or RCUS or REGN?
By revenue growth (latest reported year), Halozyme Therapeutics, Inc.
(HALO) is pulling ahead at 37. 6% versus -29. 3% for OmniAb, Inc. (OABI). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -25. 4% for Halozyme Therapeutics, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — OABI or HALO or RCUS or REGN?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus -347. 0% for OmniAb, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -383. 1% for OABI. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is OABI or HALO or RCUS or REGN more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Halozyme Therapeutics, Inc. (HALO) is the more undervalued stock at a PEG of 0. 35x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Halozyme Therapeutics, Inc. (HALO) trades at 8. 1x forward P/E versus 15. 3x for Regeneron Pharmaceuticals, Inc. — 7. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for OABI: 172. 1% to $4. 00.
08Which pays a better dividend — OABI or HALO or RCUS or REGN?
In this comparison, REGN (0.
5% yield) pays a dividend. OABI, HALO, RCUS do not pay a meaningful dividend and should not be held primarily for income.
09Is OABI or HALO or RCUS or REGN better for a retirement portfolio?
For long-horizon retirement investors, Halozyme Therapeutics, Inc.
(HALO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 56), +570. 7% 10Y return). Arcus Biosciences, Inc. (RCUS) carries a higher beta of 1. 95 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (HALO: +570. 7%, RCUS: +45. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between OABI and HALO and RCUS and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: OABI is a small-cap quality compounder stock; HALO is a small-cap high-growth stock; RCUS is a small-cap quality compounder stock; REGN is a mid-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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