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Stock Comparison

ONCO vs IMVT vs RCUS vs PRAX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ONCO
Onconetix, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1M
5Y Perf.-100.0%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.+387.8%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.50B
5Y Perf.-33.3%
PRAX
Praxis Precision Medicines, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$9.63B
5Y Perf.+69.6%

ONCO vs IMVT vs RCUS vs PRAX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ONCO logoONCO
IMVT logoIMVT
RCUS logoRCUS
PRAX logoPRAX
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$1M$5.53B$2.50B$9.63B
Revenue (TTM)$815K$0.00$236M$-92K
Net Income (TTM)$-14M$-464M$-369M$-327M
Gross Margin77.6%90.7%
Operating Margin-21.9%-168.6%
Total Debt$49K$98K$99M$110K
Cash & Equiv.$5M$714M$222M$357M

ONCO vs IMVT vs RCUS vs PRAXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ONCO
IMVT
RCUS
PRAX
StockFeb 22May 26Return
Onconetix, Inc. (ONCO)1000.0-100.0%
Immunovant, Inc. (IMVT)100487.8+387.8%
Arcus Biosciences, … (RCUS)10066.7-33.3%
Praxis Precision Me… (PRAX)100169.6+69.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: ONCO vs IMVT vs RCUS vs PRAX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: IMVT and RCUS are tied at the top with 2 categories each — the right choice depends on your priorities. Arcus Biosciences, Inc. is the stronger pick specifically for growth and revenue expansion and operational efficiency and capital deployment. ONCO and PRAX also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
ONCO
Onconetix, Inc.
The Income Pick

ONCO is the clearest fit if your priority is dividends.

  • 30.9% yield; the other 3 pay no meaningful dividend
Best for: dividends
IMVT
Immunovant, Inc.
The Income Pick

IMVT carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • beta 1.37
  • 173.6% 10Y total return vs RCUS's 45.9%
  • Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
  • Beta 1.37, current ratio 11.16x
Best for: income & stability and long-term compounding
RCUS
Arcus Biosciences, Inc.
The Growth Play

RCUS is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth -4.3%, EPS growth -4.8%, 3Y rev CAGR 30.2%
  • -4.3% revenue growth vs PRAX's -100.0%
  • -35.3% ROA vs ONCO's -68.0%, ROIC -64.1% vs -32.8%
Best for: growth exposure
PRAX
Praxis Precision Medicines, Inc.
The Momentum Pick

PRAX is the clearest fit if your priority is momentum.

  • +7.7% vs ONCO's -98.6%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthRCUS logoRCUS-4.3% revenue growth vs PRAX's -100.0%
Quality / MarginsIMVT logoIMVT3.2% margin vs ONCO's -17.2%
Stability / SafetyIMVT logoIMVTBeta 1.37 vs RCUS's 1.95, lower leverage
DividendsONCO logoONCO30.9% yield; the other 3 pay no meaningful dividend
Momentum (1Y)PRAX logoPRAX+7.7% vs ONCO's -98.6%
Efficiency (ROA)RCUS logoRCUS-35.3% ROA vs ONCO's -68.0%, ROIC -64.1% vs -32.8%

ONCO vs IMVT vs RCUS vs PRAX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ONCOOnconetix, Inc.
FY 2025
License
0.0%$0
IMVTImmunovant, Inc.

Segment breakdown not available.

RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M
PRAXPraxis Precision Medicines, Inc.
FY 2024
License
76.8%$9M
Upfront Payment
23.2%$3M

ONCO vs IMVT vs RCUS vs PRAX — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLONCOLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

RCUS leads this category, winning 5 of 6 comparable metrics.

RCUS and PRAX operate at a comparable scale, with $236M and -$92,000 in trailing revenue. Profitability is closely matched — net margins range from -156.4% (RCUS) to -17.2% (ONCO). On growth, RCUS holds the edge at -39.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricONCO logoONCOOnconetix, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …
RevenueTrailing 12 months$815,371$0$236M-$92,000
EBITDAEarnings before interest/tax-$18M-$487M-$391M-$357M
Net IncomeAfter-tax profit-$14M-$464M-$369M-$327M
Free Cash FlowCash after capex-$10M-$423M-$489M-$283M
Gross MarginGross profit ÷ Revenue+77.6%+90.7%
Operating MarginEBIT ÷ Revenue-21.9%-168.6%
Net MarginNet income ÷ Revenue-17.2%-156.4%
FCF MarginFCF ÷ Revenue-11.9%-2.1%
Rev. Growth (YoY)Latest quarter vs prior year-57.4%-39.3%
EPS Growth (YoY)Latest quarter vs prior year+120.9%+19.7%+10.5%+2.7%
RCUS leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

ONCO leads this category, winning 2 of 3 comparable metrics.
MetricONCO logoONCOOnconetix, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …
Market CapShares × price$1M$5.5B$2.5B$9.6B
Enterprise ValueMkt cap + debt − cash-$4M$4.8B$2.4B$9.3B
Trailing P/EPrice ÷ TTM EPS-0.09x-9.97x-7.54x-24.72x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue1.70x10.11x
Price / BookPrice ÷ Book value/share0.08x5.83x4.22x8.54x
Price / FCFMarket cap ÷ FCF
ONCO leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

Evenly matched — ONCO and RCUS each lead in 3 of 9 comparable metrics.

PRAX delivers a -43.0% return on equity — every $100 of shareholder capital generates $-43 in annual profit, vs $-190 for ONCO. PRAX carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to RCUS's 0.16x. On the Piotroski fundamental quality scale (0–9), ONCO scores 5/9 vs RCUS's 0/9, reflecting solid financial health.

MetricONCO logoONCOOnconetix, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …
ROE (TTM)Return on equity-189.8%-47.1%-69.0%-43.0%
ROA (TTM)Return on assets-68.0%-44.1%-35.3%-40.2%
ROICReturn on invested capital-32.8%-64.1%-65.0%
ROCEReturn on capital employed-49.4%-66.1%-42.1%-49.3%
Piotroski ScoreFundamental quality 0–95203
Debt / EquityFinancial leverage0.00x0.00x0.16x0.00x
Net DebtTotal debt minus cash-$5M-$714M-$123M-$357M
Cash & Equiv.Liquid assets$5M$714M$222M$357M
Total DebtShort + long-term debt$48,774$98,000$99M$110,000
Interest CoverageEBIT ÷ Interest expense-26.95x-13.38x
Evenly matched — ONCO and RCUS each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

PRAX leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $0 for ONCO. Over the past 12 months, PRAX leads with a +775.0% total return vs ONCO's -98.6%. The 3-year compound annual growth rate (CAGR) favors PRAX at 174.9% vs ONCO's -97.2% — a key indicator of consistent wealth creation.

MetricONCO logoONCOOnconetix, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …
YTD ReturnYear-to-date-95.0%+5.1%+6.5%+16.4%
1-Year ReturnPast 12 months-98.6%+96.1%+209.6%+775.0%
3-Year ReturnCumulative with dividends-100.0%+40.9%+24.9%+1976.5%
5-Year ReturnCumulative with dividends-100.0%+62.4%-18.6%-20.8%
10-Year ReturnCumulative with dividends-100.0%+173.6%+45.9%-20.1%
CAGR (3Y)Annualised 3-year return-97.2%+12.1%+7.7%+174.9%
PRAX leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — IMVT and PRAX each lead in 1 of 2 comparable metrics.

IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than RCUS's 1.95 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PRAX currently trades 93.6% from its 52-week high vs ONCO's 0.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricONCO logoONCOOnconetix, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …
Beta (5Y)Sensitivity to S&P 5001.41x1.37x1.95x1.55x
52-Week HighHighest price in past year$74.30$30.09$28.72$356.00
52-Week LowLowest price in past year$0.37$13.36$7.06$35.18
% of 52W HighCurrent price vs 52-week peak+0.5%+90.5%+86.3%+93.6%
RSI (14)Momentum oscillator 0–10028.860.260.555.6
Avg Volume (50D)Average daily shares traded9.4M1.4M1.2M378K
Evenly matched — IMVT and PRAX each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: IMVT as "Buy", RCUS as "Buy", PRAX as "Buy". Consensus price targets imply 67.2% upside for IMVT (target: $46) vs 21.0% for RCUS (target: $30). ONCO is the only dividend payer here at 30.89% yield — a key consideration for income-focused portfolios.

MetricONCO logoONCOOnconetix, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…PRAX logoPRAXPraxis Precision …
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$45.50$30.00$544.40
# AnalystsCovering analysts231816
Dividend YieldAnnual dividend ÷ price+30.9%
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS$0.12
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

RCUS leads in 1 of 6 categories (Income & Cash Flow). ONCO leads in 1 (Valuation Metrics). 2 tied.

Best OverallOnconetix, Inc. (ONCO)Leads 1 of 6 categories
Loading custom metrics...

ONCO vs IMVT vs RCUS vs PRAX: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is ONCO or IMVT or RCUS or PRAX a better buy right now?

For growth investors, Arcus Biosciences, Inc.

(RCUS) is the stronger pick with -4. 3% revenue growth year-over-year, versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). Analysts rate Immunovant, Inc. (IMVT) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ONCO or IMVT or RCUS or PRAX?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +62. 4%, compared to -100. 0% for Onconetix, Inc. (ONCO). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus ONCO's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ONCO or IMVT or RCUS or PRAX?

By beta (market sensitivity over 5 years), Immunovant, Inc.

(IMVT) is the lower-risk stock at 1. 37β versus Arcus Biosciences, Inc. 's 1. 95β — meaning RCUS is approximately 42% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Praxis Precision Medicines, Inc. (PRAX) carries a lower debt/equity ratio of 0% versus 16% for Arcus Biosciences, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — ONCO or IMVT or RCUS or PRAX?

By revenue growth (latest reported year), Arcus Biosciences, Inc.

(RCUS) is pulling ahead at -4. 3% versus -100. 0% for Praxis Precision Medicines, Inc. (PRAX). On earnings-per-share growth, the picture is similar: Onconetix, Inc. grew EPS 99. 1% year-over-year, compared to -45. 2% for Immunovant, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ONCO or IMVT or RCUS or PRAX?

Immunovant, Inc.

(IMVT) is the more profitable company, earning 0. 0% net margin versus -1721. 0% for Onconetix, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -778. 2% for ONCO. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — ONCO or IMVT or RCUS or PRAX?

In this comparison, ONCO (30.

9% yield) pays a dividend. IMVT, RCUS, PRAX do not pay a meaningful dividend and should not be held primarily for income.

07

Is ONCO or IMVT or RCUS or PRAX better for a retirement portfolio?

For long-horizon retirement investors, Onconetix, Inc.

(ONCO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (30. 9% yield). Arcus Biosciences, Inc. (RCUS) carries a higher beta of 1. 95 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ONCO: -100. 0%, RCUS: +45. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between ONCO and IMVT and RCUS and PRAX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ONCO is a small-cap income-oriented stock; IMVT is a small-cap quality compounder stock; RCUS is a small-cap quality compounder stock; PRAX is a small-cap quality compounder stock. ONCO pays a dividend while IMVT, RCUS, PRAX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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