OPK
OPKO Health, Inc.
Medical - Diagnostics & Research
Market Cap$846M
5Y Perf.-50.9%
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Stock Comparison
OPK vs DBVT
Revenue, margins, valuation, and 5-year total return — side by side.
DBVT
DBV Technologies S.A.
Biotechnology
Market Cap$1712.35T
5Y Perf.-58.8%
OPK vs DBVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | OPK | DBVT |
|---|---|---|
| Industry | Medical - Diagnostics & Research | Biotechnology |
| Market Cap | $846M | $1712.35T |
| Revenue (TTM) | $581M | $0.00 |
| Net Income (TTM) | $-213M | $-168M |
| Gross Margin | 47.7% | — |
| Operating Margin | -17.4% | — |
| Total Debt | $434M | $22M |
| Cash & Equiv. | $369M | $194M |
OPK vs DBVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
OPK
DBVT
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| OPKO Health, Inc. (OPK) | 100 | 49.1 | -50.9% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: OPK vs DBVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: OPK leads in 3 of 6 categories, making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. DBV Technologies S.A. is the stronger pick specifically for profitability and margin quality and recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
OPK
OPKO Health, Inc.
The Income Pick
OPK carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 0 yrs, beta 1.25
- Rev growth -14.9%, EPS growth -291.1%, 3Y rev CAGR -15.5%
- Lower volatility, beta 1.25, Low D/E 34.2%, current ratio 3.97x
Best for: income & stability and growth exposure
DBVT
DBV Technologies S.A.
The Long-Run Compounder
DBVT is the clearest fit if your priority is long-term compounding.
- -87.0% 10Y total return vs OPK's -89.1%
- 0.3% margin vs OPK's -36.6%
- +110.4% vs OPK's -10.4%
Best for: long-term compounding
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | OPK | -14.9% revenue growth vs DBVT's -100.0% |
| Quality / Margins | DBVT | 0.3% margin vs OPK's -36.6% |
| Stability / Safety | OPK | Beta 1.25 vs DBVT's 1.26 |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | DBVT | +110.4% vs OPK's -10.4% |
| Efficiency (ROA) | OPK | -11.0% ROA vs DBVT's -89.0% |
OPK vs DBVT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
FY 2025
Segment breakdown not available.
OPK vs DBVT — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLDBVTLAGGINGOPK
OPKOPKO Health, Inc.
0leads
DBVTDBV Technologies S.A.
2leads
6 Total Categories
CATEGORYLEADERvs OPKMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
DBVT1/1
Valuation MetricsMultiples, price ratios, and targets
Tied
—
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
Tied
—
Total Returns1Y, 3Y, 5Y total returns with dividends
DBVT6/6
Risk & VolatilityBeta, volatility, and downside exposure
Tied
—
Analyst OutlookRatings, price targets, and dividends
—
—
Income & Cash Flow (Last 12 Months)
DBVT leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
OPK and DBVT operate at a comparable scale, with $581M and $0 in trailing revenue.
| Metric | OPKOPKO Health, Inc. | DBVTDBV Technologies … |
|---|---|---|
| RevenueTrailing 12 months | $581M | $0 |
| EBITDAEarnings before interest/tax | -$33M | -$112M |
| Net IncomeAfter-tax profit | -$213M | -$168M |
| Free Cash FlowCash after capex | -$174M | -$151M |
| Gross MarginGross profit ÷ Revenue | +47.7% | — |
| Operating MarginEBIT ÷ Revenue | -17.4% | — |
| Net MarginNet income ÷ Revenue | -36.6% | — |
| FCF MarginFCF ÷ Revenue | -30.0% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | -17.2% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +30.0% | +91.5% |
DBVT leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
Evenly matched — OPK and DBVT each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | OPKOPKO Health, Inc. | DBVTDBV Technologies … |
|---|---|---|
| Market CapShares × price | $846M | $1712.35T |
| Enterprise ValueMkt cap + debt − cash | $910M | $1712.35T |
| Trailing P/EPrice ÷ TTM EPS | -3.73x | -0.76x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 1.39x | — |
| Price / BookPrice ÷ Book value/share | 0.68x | 0.66x |
| Price / FCFMarket cap ÷ FCF | — | — |
Evenly matched — OPK and DBVT each lead in 1 of 2 comparable metrics.
Profitability & Efficiency
Evenly matched — OPK and DBVT each lead in 4 of 8 comparable metrics.
Profitability & Efficiency
OPK delivers a -16.8% return on equity — every $100 of shareholder capital generates $-17 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to OPK's 0.34x. On the Piotroski fundamental quality scale (0–9), DBVT scores 4/9 vs OPK's 3/9, reflecting mixed financial health.
| Metric | OPKOPKO Health, Inc. | DBVTDBV Technologies … |
|---|---|---|
| ROE (TTM)Return on equity | -16.8% | -130.2% |
| ROA (TTM)Return on assets | -11.0% | -89.0% |
| ROICReturn on invested capital | -11.9% | — |
| ROCEReturn on capital employed | -11.5% | -145.7% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 |
| Debt / EquityFinancial leverage | 0.34x | 0.13x |
| Net DebtTotal debt minus cash | $65M | -$172M |
| Cash & Equiv.Liquid assets | $369M | $194M |
| Total DebtShort + long-term debt | $434M | $22M |
| Interest CoverageEBIT ÷ Interest expense | -1.10x | -189.82x |
Evenly matched — OPK and DBVT each lead in 4 of 8 comparable metrics.
Total Returns (Dividends Reinvested)
DBVT leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in DBVT five years ago would be worth $3,090 today (with dividends reinvested), compared to $2,947 for OPK. Over the past 12 months, DBVT leads with a +110.4% total return vs OPK's -10.4%. The 3-year compound annual growth rate (CAGR) favors DBVT at 6.2% vs OPK's -15.6% — a key indicator of consistent wealth creation.
| Metric | OPKOPKO Health, Inc. | DBVTDBV Technologies … |
|---|---|---|
| YTD ReturnYear-to-date | -11.8% | +4.9% |
| 1-Year ReturnPast 12 months | -10.4% | +110.4% |
| 3-Year ReturnCumulative with dividends | -39.8% | +19.7% |
| 5-Year ReturnCumulative with dividends | -70.5% | -69.1% |
| 10-Year ReturnCumulative with dividends | -89.1% | -87.0% |
| CAGR (3Y)Annualised 3-year return | -15.6% | +6.2% |
DBVT leads this category, winning 6 of 6 comparable metrics.
Risk & Volatility
Evenly matched — OPK and DBVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
OPK is the less volatile stock with a 1.25 beta — it tends to amplify market swings less than DBVT's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. DBVT currently trades 76.3% from its 52-week high vs OPK's 70.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | OPKOPKO Health, Inc. | DBVTDBV Technologies … |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.25x | 1.26x |
| 52-Week HighHighest price in past year | $1.60 | $26.18 |
| 52-Week LowLowest price in past year | $0.98 | $7.53 |
| % of 52W HighCurrent price vs 52-week peak | +70.0% | +76.3% |
| RSI (14)Momentum oscillator 0–100 | 41.8 | 48.1 |
| Avg Volume (50D)Average daily shares traded | 2.4M | 252K |
Evenly matched — OPK and DBVT each lead in 1 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates OPK as "Buy" and DBVT as "Buy". Consensus price targets imply 156.2% upside for OPK (target: $3) vs 131.8% for DBVT (target: $46).
| Metric | OPKOPKO Health, Inc. | DBVTDBV Technologies … |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $2.87 | $46.33 |
| # AnalystsCovering analysts | 13 | 15 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | 0 | 0 |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +5.6% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
DBVT leads in 2 of 6 categories — strongest in Income & Cash Flow and Total Returns. 3 categories are tied.
Best OverallDBV Technologies S.A. (DBVT)Leads 2 of 6 categories
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OPK vs DBVT: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is OPK or DBVT a better buy right now?
Analysts rate OPKO Health, Inc.
(OPK) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — OPK or DBVT?
Over the past 5 years, DBV Technologies S.
A. (DBVT) delivered a total return of -69. 1%, compared to -70. 5% for OPKO Health, Inc. (OPK). Over 10 years, the gap is even starker: DBVT returned -87. 0% versus OPK's -89. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — OPK or DBVT?
By beta (market sensitivity over 5 years), OPKO Health, Inc.
(OPK) is the lower-risk stock at 1. 25β versus DBV Technologies S. A. 's 1. 26β — meaning DBVT is approximately 0% more volatile than OPK relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 34% for OPKO Health, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — OPK or DBVT?
On earnings-per-share growth, the picture is similar: OPKO Health, Inc.
grew EPS -291. 1% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — OPK or DBVT?
DBV Technologies S.
A. (DBVT) is the more profitable company, earning 0. 0% net margin versus -37. 2% for OPKO Health, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DBVT leads at 0. 0% versus -36. 1% for OPK. At the gross margin level — before operating expenses — OPK leads at 21. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — OPK or DBVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is OPK or DBVT better for a retirement portfolio?
For long-horizon retirement investors, OPKO Health, Inc.
(OPK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 25)). Both have compounded well over 10 years (OPK: -89. 1%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between OPK and DBVT?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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