OPKO Health, Inc. (OPK) Revenue History
Annual and quarterly revenue from 2014 to 2025
Compound Annual Growth Rate (CAGR)
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OPK Revenue Growth
Revenue Breakdown (FY 2025)
OPK's revenue distribution by segment and geography for fiscal year 2025
By Product/Segment
By Geography
OPK Revenue Analysis (2014–2025)
As of May 8, 2026, OPKO Health, Inc. (OPK) generated trailing twelve-month (TTM) revenue of $581.2 million, reflecting significant decline in growth of -17.2% year-over-year. The most recent quarter (Q1 2026) recorded $124.2 million in revenue, down 16.4% sequentially.
Looking at the longer-term picture, OPK's 5-year compound annual growth rate (CAGR) stands at -15.8%, indicating revenue contraction over this period. The company achieved its highest annual revenue of $1.77 billion in 2021.
Revenue diversification analysis shows OPK's business is primarily driven by Service (61%), Product (26%), and Transfer of Intellectual Property and Other (13%). With over half of revenue concentrated in Service, the company maintains significant focus in this area while developing other growth vectors.
When compared to Healthcare sector peers including PRGO (-3.6% YoY), PAHC (+32.4% YoY), and NKTR (-43.9% YoY), OPK has underperformed the peer group in terms of revenue growth. Compare OPK vs PRGO →
OPK Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| OPKCurrent | $581M | -17.2% | -15.8% | -36.1% | |
 PRGO | $4.3B | -3.6% | +0.8% | 8.1% | |
 PAHC | $1.3B | +32.4% | +10.1% | 8.5% | |
 NKTR | $55M | -43.9% | -18.4% | -236.8% | |
 LH | $14.0B | +7.3% | -0.0% | 10.9% | |
 DGX | $11.0B | +11.0% | +3.2% | 14.5% |
OPK Historical Revenue Data (2014–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $606.9M | -14.9% | $128.1M | 21.1% | $-218,985,000 | -36.1% |
| 2024 | $713.1M | -17.4% | $311.0M | 43.6% | $-152,065,000 | -21.3% |
| 2023 | $863.5M | -14.0% | $318.1M | 36.8% | $-157,021,000 | -18.2% |
| 2022 | $1.00B | -43.4% | $288.2M | 28.7% | $-226,253,000 | -22.5% |
| 2021 | $1.77B | +23.6% | $581.5M | 32.8% | $18.8M | 1.1% |
| 2020 | $1.44B | +59.1% | $541.0M | 37.7% | $57.7M | 4.0% |
| 2019 | $901.9M | -8.9% | $329.5M | 36.5% | $-274,052,000 | -30.4% |
| 2018 | $990.3M | +2.5% | $385.7M | 38.9% | $-171,197,000 | -17.3% |
| 2017 | $966.0M | -20.9% | $345.9M | 35.8% | $-276,442,000 | -28.6% |
| 2016 | $1.22B | +148.5% | $610.2M | 49.9% | $-73,275,000 | -6.0% |
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Start ComparisonOPK — Frequently Asked Questions
Quick answers to the most common questions about buying OPK stock.
Is OPK's revenue growth accelerating or slowing?
OPK revenue declined -17.2% year-over-year, contrasting with the 5-year CAGR of -15.8%. TTM revenue fell to $581M. This reverses the prior growth trend.
What is OPK's long-term revenue growth rate?
OPKO Health, Inc.'s 5-year revenue CAGR of -15.8% reflects the variable expansion pattern. Current YoY growth of -17.2% is below this long-term average.
How is OPK's revenue distributed by segment?
OPK reports revenue by product line and geographic region. Annual and quarterly breakdowns from 2014-2025 are available for download. Segment mix reveals concentration and diversification trends.