Medical - Diagnostics & Research
Compare Stocks
4 / 10Stock Comparison
OPK vs PRGO vs HLN vs PAHC
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
OPK vs PRGO vs HLN vs PAHC — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Diagnostics & Research | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic |
| Market Cap | $846M | $1.61B | $41.45B | $1.75B |
| Revenue (TTM) | $581M | $4.18B | $22.01B | $1.46B |
| Net Income (TTM) | $-213M | $-1.82B | $3.18B | $92M |
| Gross Margin | 47.7% | 34.2% | 63.9% | 31.9% |
| Operating Margin | -17.4% | -4.1% | 21.4% | 11.6% |
| Forward P/E | — | 5.6x | 22.2x | 14.2x |
| Total Debt | $434M | $3.97B | $8.59B | $762M |
| Cash & Equiv. | $369M | $532M | $1.32B | $68M |
OPK vs PRGO vs HLN vs PAHC — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 22 | May 26 | Return |
|---|---|---|---|
| OPKO Health, Inc. (OPK) | 100 | 47.5 | -52.5% |
| Perrigo Company plc (PRGO) | 100 | 28.0 | -72.0% |
| Haleon plc (HLN) | 100 | 132.4 | +32.4% |
| Phibro Animal Healt… (PAHC) | 100 | 220.5 | +120.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: OPK vs PRGO vs HLN vs PAHC
Each card shows where this stock fits in a portfolio — not just who wins on paper.
OPK is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.25, Low D/E 34.2%, current ratio 3.97x
PRGO is the #2 pick in this set and the best alternative if income & stability and defensive is your priority.
- Dividend streak 10 yrs, beta 1.18, yield 9.8%
- Beta 1.18, yield 9.8%, current ratio 2.76x
- Lower P/E (5.6x vs 22.2x)
- 9.8% yield, 10-year raise streak, vs HLN's 1.9%, (1 stock pays no dividend)
HLN carries the broadest edge in this set and is the clearest fit for quality and stability.
- 14.5% margin vs PRGO's -43.5%
- Beta 0.06 vs PAHC's 1.38, lower leverage
- 10.0% ROA vs PRGO's -19.8%, ROIC 7.6% vs 3.7%
PAHC is the clearest fit if your priority is growth exposure and long-term compounding.
- Rev growth 27.4%, EPS growth 18.8%, 3Y rev CAGR 11.2%
- 128.6% 10Y total return vs HLN's 31.7%
- PEG 1.90 vs HLN's 2.63
- 27.4% revenue growth vs OPK's -14.9%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 27.4% revenue growth vs OPK's -14.9% | |
| Value | Lower P/E (5.6x vs 22.2x) | |
| Quality / Margins | 14.5% margin vs PRGO's -43.5% | |
| Stability / Safety | Beta 0.06 vs PAHC's 1.38, lower leverage | |
| Dividends | 9.8% yield, 10-year raise streak, vs HLN's 1.9%, (1 stock pays no dividend) | |
| Momentum (1Y) | +125.1% vs PRGO's -51.2% | |
| Efficiency (ROA) | 10.0% ROA vs PRGO's -19.8%, ROIC 7.6% vs 3.7% |
OPK vs PRGO vs HLN vs PAHC — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
OPK vs PRGO vs HLN vs PAHC — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HLN leads in 2 of 6 categories
PRGO leads 2 • PAHC leads 1 • OPK leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
HLN leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
HLN is the larger business by revenue, generating $22.0B annually — 37.9x OPK's $581M. HLN is the more profitable business, keeping 14.5% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, PAHC holds the edge at +20.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $581M | $4.2B | $22.0B | $1.5B |
| EBITDAEarnings before interest/tax | -$33M | $58M | $5.3B | $220M |
| Net IncomeAfter-tax profit | -$213M | -$1.8B | $3.2B | $92M |
| Free Cash FlowCash after capex | -$174M | $108M | $3.1B | $47M |
| Gross MarginGross profit ÷ Revenue | +47.7% | +34.2% | +63.9% | +31.9% |
| Operating MarginEBIT ÷ Revenue | -17.4% | -4.1% | +21.4% | +11.6% |
| Net MarginNet income ÷ Revenue | -36.6% | -43.5% | +14.5% | +6.3% |
| FCF MarginFCF ÷ Revenue | -30.0% | +2.6% | +14.2% | +3.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | -17.2% | -7.2% | -0.4% | +20.9% |
| EPS Growth (YoY)Latest quarter vs prior year | +30.0% | -56.4% | +18.8% | +7.4% |
Valuation Metrics
PRGO leads this category, winning 5 of 7 comparable metrics.
Valuation Metrics
At 19.0x trailing earnings, HLN trades at a 48% valuation discount to PAHC's 36.3x P/E. Adjusting for growth (PEG ratio), HLN offers better value at 2.25x vs PAHC's 4.85x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $846M | $1.6B | $41.4B | $1.7B |
| Enterprise ValueMkt cap + debt − cash | $910M | $5.1B | $51.3B | $2.4B |
| Trailing P/EPrice ÷ TTM EPS | -3.73x | -1.14x | 19.01x | 36.27x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 5.56x | 22.22x | 14.23x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 2.25x | 4.85x |
| EV / EBITDAEnterprise value multiple | — | 7.42x | 13.62x | 15.65x |
| Price / SalesMarket cap ÷ Revenue | 1.39x | 0.38x | 2.83x | 1.35x |
| Price / BookPrice ÷ Book value/share | 0.68x | 0.55x | 1.87x | 6.15x |
| Price / FCFMarket cap ÷ FCF | — | 11.12x | 15.47x | 41.82x |
Profitability & Efficiency
Evenly matched — OPK and HLN and PAHC each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
PAHC delivers a 30.8% return on equity — every $100 of shareholder capital generates $31 in annual profit, vs $-51 for PRGO. OPK carries lower financial leverage with a 0.34x debt-to-equity ratio, signaling a more conservative balance sheet compared to PAHC's 2.67x. On the Piotroski fundamental quality scale (0–9), HLN scores 8/9 vs OPK's 3/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -16.8% | -50.7% | +19.9% | +30.8% |
| ROA (TTM)Return on assets | -11.0% | -19.8% | +10.0% | +6.7% |
| ROICReturn on invested capital | -11.9% | +3.7% | +7.6% | +9.8% |
| ROCEReturn on capital employed | -11.5% | +4.3% | +8.6% | +12.0% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 8 | 5 |
| Debt / EquityFinancial leverage | 0.34x | 1.35x | 0.52x | 2.67x |
| Net DebtTotal debt minus cash | $65M | $3.4B | $7.3B | $694M |
| Cash & Equiv.Liquid assets | $369M | $532M | $1.3B | $68M |
| Total DebtShort + long-term debt | $434M | $4.0B | $8.6B | $762M |
| Interest CoverageEBIT ÷ Interest expense | -1.10x | -7.20x | 7.80x | 3.64x |
Total Returns (Dividends Reinvested)
PAHC leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in PAHC five years ago would be worth $16,597 today (with dividends reinvested), compared to $2,947 for OPK. Over the past 12 months, PAHC leads with a +125.1% total return vs PRGO's -51.2%. The 3-year compound annual growth rate (CAGR) favors PAHC at 45.9% vs PRGO's -25.2% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -11.8% | -13.5% | -5.6% | +16.0% |
| 1-Year ReturnPast 12 months | -10.4% | -51.2% | -11.7% | +125.1% |
| 3-Year ReturnCumulative with dividends | -39.8% | -58.1% | +10.4% | +210.4% |
| 5-Year ReturnCumulative with dividends | -70.5% | -60.1% | +31.7% | +66.0% |
| 10-Year ReturnCumulative with dividends | -89.1% | -77.7% | +31.7% | +128.6% |
| CAGR (3Y)Annualised 3-year return | -15.6% | -25.2% | +3.4% | +45.9% |
Risk & Volatility
HLN leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
HLN is the less volatile stock with a 0.06 beta — it tends to amplify market swings less than PAHC's 1.38 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HLN currently trades 81.5% from its 52-week high vs PRGO's 41.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.25x | 1.18x | 0.06x | 1.38x |
| 52-Week HighHighest price in past year | $1.60 | $28.44 | $11.42 | $60.08 |
| 52-Week LowLowest price in past year | $0.98 | $9.23 | $8.71 | $19.00 |
| % of 52W HighCurrent price vs 52-week peak | +70.0% | +41.2% | +81.5% | +71.8% |
| RSI (14)Momentum oscillator 0–100 | 41.8 | 60.9 | 36.0 | 60.3 |
| Avg Volume (50D)Average daily shares traded | 2.4M | 3.4M | 8.0M | 302K |
Analyst Outlook
PRGO leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: OPK as "Buy", PRGO as "Hold", HLN as "Buy", PAHC as "Buy". Consensus price targets imply 156.2% upside for OPK (target: $3) vs 9.6% for HLN (target: $10). For income investors, PRGO offers the higher dividend yield at 9.81% vs PAHC's 1.11%.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | $2.87 | $20.00 | $10.20 | $49.00 |
| # AnalystsCovering analysts | 13 | 36 | 4 | 13 |
| Dividend YieldAnnual dividend ÷ price | — | +9.8% | +1.9% | +1.1% |
| Dividend StreakConsecutive years of raises | 0 | 10 | 2 | 0 |
| Dividend / ShareAnnual DPS | — | $1.15 | $0.13 | $0.48 |
| Buyback YieldShare repurchases ÷ mkt cap | +5.6% | 0.0% | +2.1% | 0.0% |
HLN leads in 2 of 6 categories (Income & Cash Flow, Risk & Volatility). PRGO leads in 2 (Valuation Metrics, Analyst Outlook). 1 tied.
OPK vs PRGO vs HLN vs PAHC: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is OPK or PRGO or HLN or PAHC a better buy right now?
For growth investors, Phibro Animal Health Corporation (PAHC) is the stronger pick with 27.
4% revenue growth year-over-year, versus -14. 9% for OPKO Health, Inc. (OPK). Haleon plc (HLN) offers the better valuation at 19. 0x trailing P/E (22. 2x forward), making it the more compelling value choice. Analysts rate OPKO Health, Inc. (OPK) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — OPK or PRGO or HLN or PAHC?
On trailing P/E, Haleon plc (HLN) is the cheapest at 19.
0x versus Phibro Animal Health Corporation at 36. 3x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Phibro Animal Health Corporation wins at 1. 90x versus Haleon plc's 2. 63x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — OPK or PRGO or HLN or PAHC?
Over the past 5 years, Phibro Animal Health Corporation (PAHC) delivered a total return of +66.
0%, compared to -70. 5% for OPKO Health, Inc. (OPK). Over 10 years, the gap is even starker: PAHC returned +128. 6% versus OPK's -89. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — OPK or PRGO or HLN or PAHC?
By beta (market sensitivity over 5 years), Haleon plc (HLN) is the lower-risk stock at 0.
06β versus Phibro Animal Health Corporation's 1. 38β — meaning PAHC is approximately 2157% more volatile than HLN relative to the S&P 500. On balance sheet safety, OPKO Health, Inc. (OPK) carries a lower debt/equity ratio of 34% versus 3% for Phibro Animal Health Corporation — giving it more financial flexibility in a downturn.
05Which is growing faster — OPK or PRGO or HLN or PAHC?
By revenue growth (latest reported year), Phibro Animal Health Corporation (PAHC) is pulling ahead at 27.
4% versus -14. 9% for OPKO Health, Inc. (OPK). On earnings-per-share growth, the picture is similar: Phibro Animal Health Corporation grew EPS 1883% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, PAHC leads at 11. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — OPK or PRGO or HLN or PAHC?
Haleon plc (HLN) is the more profitable company, earning 15.
1% net margin versus -37. 2% for OPKO Health, Inc. — meaning it keeps 15. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HLN leads at 22. 4% versus -36. 1% for OPK. At the gross margin level — before operating expenses — HLN leads at 64. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is OPK or PRGO or HLN or PAHC more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Phibro Animal Health Corporation (PAHC) is the more undervalued stock at a PEG of 1. 90x versus Haleon plc's 2. 63x. Both stocks trade at elevated growth-adjusted valuations, so expected growth needs to materialise. On forward earnings alone, Perrigo Company plc (PRGO) trades at 5. 6x forward P/E versus 22. 2x for Haleon plc — 16. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for OPK: 156. 2% to $2. 87.
08Which pays a better dividend — OPK or PRGO or HLN or PAHC?
In this comparison, PRGO (9.
8% yield), HLN (1. 9% yield), PAHC (1. 1% yield) pay a dividend. OPK does not pay a meaningful dividend and should not be held primarily for income.
09Is OPK or PRGO or HLN or PAHC better for a retirement portfolio?
For long-horizon retirement investors, Haleon plc (HLN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
06), 1. 9% yield). Both have compounded well over 10 years (HLN: +31. 7%, OPK: -89. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between OPK and PRGO and HLN and PAHC?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: OPK is a small-cap quality compounder stock; PRGO is a small-cap income-oriented stock; HLN is a mid-cap quality compounder stock; PAHC is a small-cap high-growth stock. PRGO, HLN, PAHC pay a dividend while OPK does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.