Biotechnology
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ORIC vs ARVN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
ORIC vs ARVN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $912M | $652M |
| Revenue (TTM) | $0.00 | $263M |
| Net Income (TTM) | $-135M | $-81M |
| Gross Margin | — | 99.5% |
| Operating Margin | — | -44.0% |
| Total Debt | $12M | $9M |
| Cash & Equiv. | $46M | $143M |
ORIC vs ARVN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| ORIC Pharmaceutical… (ORIC) | 100 | 30.4 | -69.6% |
| Arvinas, Inc. (ARVN) | 100 | 30.6 | -69.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ORIC vs ARVN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ORIC has the current edge in this matchup, primarily because of its strength in income & stability and sleep-well-at-night.
- beta 1.12
- Lower volatility, beta 1.12, Low D/E 3.0%, current ratio 14.13x
- Beta 1.12, current ratio 14.13x
ARVN is the clearest fit if your priority is growth exposure and long-term compounding.
- Rev growth -0.3%, EPS growth 53.8%, 3Y rev CAGR 26.0%
- -36.5% 10Y total return vs ORIC's -65.8%
- -0.3% revenue growth vs ORIC's -1.8%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | -0.3% revenue growth vs ORIC's -1.8% | |
| Stability / Safety | Beta 1.12 vs ARVN's 1.15 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +87.4% vs ARVN's +52.8% | |
| Efficiency (ROA) | -9.3% ROA vs ORIC's -33.3%, ROIC -22.4% vs -39.9% |
ORIC vs ARVN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ORIC vs ARVN — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
ORIC leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
ARVN and ORIC operate at a comparable scale, with $263M and $0 in trailing revenue.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $0 | $263M |
| EBITDAEarnings before interest/tax | -$149M | -$111M |
| Net IncomeAfter-tax profit | -$135M | -$81M |
| Free Cash FlowCash after capex | -$111M | -$276M |
| Gross MarginGross profit ÷ Revenue | — | +99.5% |
| Operating MarginEBIT ÷ Revenue | — | -44.0% |
| Net MarginNet income ÷ Revenue | — | -30.8% |
| FCF MarginFCF ÷ Revenue | — | -105.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -84.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +19.0% | -65.1% |
Valuation Metrics
ARVN leads this category, winning 2 of 2 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $912M | $652M |
| Enterprise ValueMkt cap + debt − cash | $878M | $517M |
| Trailing P/EPrice ÷ TTM EPS | -5.99x | -7.96x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 2.48x |
| Price / BookPrice ÷ Book value/share | 2.01x | 1.52x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
ARVN leads this category, winning 8 of 8 comparable metrics.
Profitability & Efficiency
ARVN delivers a -14.3% return on equity — every $100 of shareholder capital generates $-14 in annual profit, vs $-35 for ORIC. ARVN carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to ORIC's 0.03x. On the Piotroski fundamental quality scale (0–9), ARVN scores 4/9 vs ORIC's 3/9, reflecting mixed financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -35.3% | -14.3% |
| ROA (TTM)Return on assets | -33.3% | -9.3% |
| ROICReturn on invested capital | -39.9% | -22.4% |
| ROCEReturn on capital employed | -44.7% | -16.0% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 |
| Debt / EquityFinancial leverage | 0.03x | 0.02x |
| Net DebtTotal debt minus cash | -$34M | -$134M |
| Cash & Equiv.Liquid assets | $46M | $143M |
| Total DebtShort + long-term debt | $12M | $9M |
| Interest CoverageEBIT ÷ Interest expense | — | — |
Total Returns (Dividends Reinvested)
ORIC leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ORIC five years ago would be worth $3,689 today (with dividends reinvested), compared to $1,601 for ARVN. Over the past 12 months, ORIC leads with a +87.4% total return vs ARVN's +52.8%. The 3-year compound annual growth rate (CAGR) favors ORIC at 19.1% vs ARVN's -25.5% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +7.8% | -11.2% |
| 1-Year ReturnPast 12 months | +87.4% | +52.8% |
| 3-Year ReturnCumulative with dividends | +68.8% | -58.7% |
| 5-Year ReturnCumulative with dividends | -63.1% | -84.0% |
| 10-Year ReturnCumulative with dividends | -65.8% | -36.5% |
| CAGR (3Y)Annualised 3-year return | +19.1% | -25.5% |
Risk & Volatility
Evenly matched — ORIC and ARVN each lead in 1 of 2 comparable metrics.
Risk & Volatility
ORIC is the less volatile stock with a 1.12 beta — it tends to amplify market swings less than ARVN's 1.15 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ARVN currently trades 70.2% from its 52-week high vs ORIC's 59.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.12x | 1.15x |
| 52-Week HighHighest price in past year | $14.93 | $14.51 |
| 52-Week LowLowest price in past year | $4.52 | $5.90 |
| % of 52W HighCurrent price vs 52-week peak | +59.0% | +70.2% |
| RSI (14)Momentum oscillator 0–100 | 39.7 | 42.6 |
| Avg Volume (50D)Average daily shares traded | 1.9M | 808K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates ORIC as "Buy" and ARVN as "Buy". Consensus price targets imply 146.9% upside for ORIC (target: $22) vs 27.6% for ARVN (target: $13).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $21.75 | $13.00 |
| # AnalystsCovering analysts | 10 | 26 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +14.1% |
ORIC leads in 2 of 6 categories (Income & Cash Flow, Total Returns). ARVN leads in 2 (Valuation Metrics, Profitability & Efficiency). 1 tied.
ORIC vs ARVN: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is ORIC or ARVN a better buy right now?
Analysts rate ORIC Pharmaceuticals, Inc.
(ORIC) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ORIC or ARVN?
Over the past 5 years, ORIC Pharmaceuticals, Inc.
(ORIC) delivered a total return of -63. 1%, compared to -84. 0% for Arvinas, Inc. (ARVN). Over 10 years, the gap is even starker: ARVN returned -36. 5% versus ORIC's -65. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ORIC or ARVN?
By beta (market sensitivity over 5 years), ORIC Pharmaceuticals, Inc.
(ORIC) is the lower-risk stock at 1. 12β versus Arvinas, Inc. 's 1. 15β — meaning ARVN is approximately 3% more volatile than ORIC relative to the S&P 500. On balance sheet safety, Arvinas, Inc. (ARVN) carries a lower debt/equity ratio of 2% versus 3% for ORIC Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ORIC or ARVN?
On earnings-per-share growth, the picture is similar: Arvinas, Inc.
grew EPS 53. 8% year-over-year, compared to 19. 7% for ORIC Pharmaceuticals, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ORIC or ARVN?
ORIC Pharmaceuticals, Inc.
(ORIC) is the more profitable company, earning 0. 0% net margin versus -30. 8% for Arvinas, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ORIC leads at 0. 0% versus -43. 8% for ARVN. At the gross margin level — before operating expenses — ARVN leads at 98. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ORIC or ARVN?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ORIC or ARVN better for a retirement portfolio?
For long-horizon retirement investors, ORIC Pharmaceuticals, Inc.
(ORIC) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 12)). Both have compounded well over 10 years (ORIC: -65. 8%, ARVN: -36. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ORIC and ARVN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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