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Stock Comparison

OSUR vs TMO vs DHR vs ABT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
OSUR
OraSure Technologies, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$225M
5Y Perf.-78.5%
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$176.36B
5Y Perf.+35.9%
DHR
Danaher Corporation

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$124.33B
5Y Perf.+18.9%
ABT
Abbott Laboratories

Medical - Devices

HealthcareNYSE • US
Market Cap$151.30B
5Y Perf.-8.3%

OSUR vs TMO vs DHR vs ABT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
OSUR logoOSUR
TMO logoTMO
DHR logoDHR
ABT logoABT
IndustryMedical - Instruments & SuppliesMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Devices
Market Cap$225M$176.36B$124.33B$151.30B
Revenue (TTM)$85M$45.20B$24.78B$43.84B
Net Income (TTM)$-53M$6.86B$3.69B$13.98B
Gross Margin38.8%39.4%60.7%54.0%
Operating Margin-58.6%17.8%21.0%17.8%
Forward P/E19.1x20.8x15.9x
Total Debt$13M$40.85B$18.42B$15.28B
Cash & Equiv.$199K$9.86B$4.62B$7.62B

OSUR vs TMO vs DHR vs ABTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

OSUR
TMO
DHR
ABT
StockMay 20May 26Return
OraSure Technologie… (OSUR)10021.5-78.5%
Thermo Fisher Scien… (TMO)100135.9+35.9%
Danaher Corporation (DHR)100118.9+18.9%
Abbott Laboratories (ABT)10091.7-8.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: OSUR vs TMO vs DHR vs ABT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABT leads in 6 of 7 categories, making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Thermo Fisher Scientific Inc. is the stronger pick specifically for recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
OSUR
OraSure Technologies, Inc.
The Specific-Use Pick

OSUR plays a supporting role in this comparison — it may shine differently against other peers.

Best for: healthcare exposure
TMO
Thermo Fisher Scientific Inc.
The Long-Run Compounder

TMO is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 229.1% 10Y total return vs DHR's 219.3%
  • +16.8% vs ABT's -33.2%
Best for: long-term compounding
DHR
Danaher Corporation
The Quality Angle

DHR lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
ABT
Abbott Laboratories
The Income Pick

ABT carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 11 yrs, beta 0.25, yield 2.5%
  • Rev growth 4.6%, EPS growth 133.6%, 3Y rev CAGR -0.9%
  • Lower volatility, beta 0.25, Low D/E 31.9%, current ratio 1.67x
  • PEG 0.53 vs DHR's 34.35
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthABT logoABT4.6% revenue growth vs OSUR's -38.1%
ValueABT logoABTLower P/E (15.9x vs 19.1x), PEG 0.53 vs 9.05
Quality / MarginsABT logoABT31.9% margin vs OSUR's -61.9%
Stability / SafetyABT logoABTBeta 0.25 vs OSUR's 1.45
DividendsABT logoABT2.5% yield, 11-year raise streak, vs TMO's 0.4%, (1 stock pays no dividend)
Momentum (1Y)TMO logoTMO+16.8% vs ABT's -33.2%
Efficiency (ROA)ABT logoABT16.6% ROA vs OSUR's -12.8%, ROIC 9.9% vs -20.0%

OSUR vs TMO vs DHR vs ABT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

OSUROraSure Technologies, Inc.
FY 2025
Product And Services
94.8%$109M
Other Revenues
5.2%$6M
TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B
DHRDanaher Corporation
FY 2025
Revenue from Contract with Customer, Measurement, Recurring
81.9%$20.1B
Revenue from Contract with Customer, Measurement, Nonrecurring
18.1%$4.4B
ABTAbbott Laboratories
FY 2024
Medical Devices
45.3%$19.0B
Diagnostic Products
22.3%$9.3B
Nutritional Products
20.1%$8.4B
Established Pharmaceutical Products
12.4%$5.2B

OSUR vs TMO vs DHR vs ABT — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLABTLAGGINGOSUR

Income & Cash Flow (Last 12 Months)

DHR leads this category, winning 3 of 6 comparable metrics.

TMO is the larger business by revenue, generating $45.2B annually — 531.0x OSUR's $85M. ABT is the more profitable business, keeping 31.9% of every revenue dollar as net income compared to OSUR's -61.9%. On growth, ABT holds the edge at +6.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricOSUR logoOSUROraSure Technolog…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…ABT logoABTAbbott Laboratori…
RevenueTrailing 12 months$85M$45.2B$24.8B$43.8B
EBITDAEarnings before interest/tax-$45M$10.5B$7.2B$10.9B
Net IncomeAfter-tax profit-$53M$6.9B$3.7B$14.0B
Free Cash FlowCash after capex-$33M$6.7B$5.3B$6.9B
Gross MarginGross profit ÷ Revenue+38.8%+39.4%+60.7%+54.0%
Operating MarginEBIT ÷ Revenue-58.6%+17.8%+21.0%+17.8%
Net MarginNet income ÷ Revenue-61.9%+15.2%+14.9%+31.9%
FCF MarginFCF ÷ Revenue-38.9%+14.9%+21.4%+15.8%
Rev. Growth (YoY)Latest quarter vs prior year-99.9%+6.2%+3.7%+6.9%
EPS Growth (YoY)Latest quarter vs prior year-52.4%+11.3%+9.8%0.0%
DHR leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — OSUR and ABT each lead in 3 of 7 comparable metrics.

At 11.4x trailing earnings, ABT trades at a 67% valuation discount to DHR's 34.9x P/E. Adjusting for growth (PEG ratio), ABT offers better value at 0.38x vs DHR's 34.35x — a lower PEG means you pay less per unit of expected earnings growth.

MetricOSUR logoOSUROraSure Technolog…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…ABT logoABTAbbott Laboratori…
Market CapShares × price$225M$176.4B$124.3B$151.3B
Enterprise ValueMkt cap + debt − cash$238M$207.4B$138.1B$159.0B
Trailing P/EPrice ÷ TTM EPS-3.33x26.75x34.85x11.39x
Forward P/EPrice ÷ next-FY EPS est.19.11x20.82x15.87x
PEG RatioP/E ÷ EPS growth rate12.67x34.35x0.38x
EV / EBITDAEnterprise value multiple19.04x18.21x15.83x
Price / SalesMarket cap ÷ Revenue1.96x3.96x5.06x3.61x
Price / BookPrice ÷ Book value/share0.67x3.34x2.38x3.18x
Price / FCFMarket cap ÷ FCF28.02x23.64x23.82x
Evenly matched — OSUR and ABT each lead in 3 of 7 comparable metrics.

Profitability & Efficiency

ABT leads this category, winning 6 of 9 comparable metrics.

ABT delivers a 27.3% return on equity — every $100 of shareholder capital generates $27 in annual profit, vs $-15 for OSUR. OSUR carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to TMO's 0.76x. On the Piotroski fundamental quality scale (0–9), DHR scores 7/9 vs OSUR's 3/9, reflecting strong financial health.

MetricOSUR logoOSUROraSure Technolog…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…ABT logoABTAbbott Laboratori…
ROE (TTM)Return on equity-15.1%+13.2%+7.1%+27.3%
ROA (TTM)Return on assets-12.8%+6.4%+4.5%+16.6%
ROICReturn on invested capital-20.0%+7.5%+5.9%+9.9%
ROCEReturn on capital employed-16.8%+9.1%+7.0%+10.8%
Piotroski ScoreFundamental quality 0–93677
Debt / EquityFinancial leverage0.04x0.76x0.35x0.32x
Net DebtTotal debt minus cash$13M$31.0B$13.8B$7.7B
Cash & Equiv.Liquid assets$199,278$9.9B$4.6B$7.6B
Total DebtShort + long-term debt$13M$40.9B$18.4B$15.3B
Interest CoverageEBIT ÷ Interest expense5.89x18.13x19.22x
ABT leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

TMO leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in TMO five years ago would be worth $10,283 today (with dividends reinvested), compared to $3,174 for OSUR. Over the past 12 months, TMO leads with a +16.8% total return vs ABT's -33.2%. The 3-year compound annual growth rate (CAGR) favors TMO at -4.0% vs OSUR's -23.5% — a key indicator of consistent wealth creation.

MetricOSUR logoOSUROraSure Technolog…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…ABT logoABTAbbott Laboratori…
YTD ReturnYear-to-date+31.5%-19.8%-23.6%-28.9%
1-Year ReturnPast 12 months+12.2%+16.8%-8.3%-33.2%
3-Year ReturnCumulative with dividends-55.2%-11.7%-15.5%-15.4%
5-Year ReturnCumulative with dividends-68.3%+2.8%-21.1%-17.9%
10-Year ReturnCumulative with dividends-53.1%+229.1%+219.3%+173.7%
CAGR (3Y)Annualised 3-year return-23.5%-4.0%-5.5%-5.4%
TMO leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — OSUR and ABT each lead in 1 of 2 comparable metrics.

ABT is the less volatile stock with a 0.25 beta — it tends to amplify market swings less than OSUR's 1.45 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. OSUR currently trades 81.9% from its 52-week high vs ABT's 62.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricOSUR logoOSUROraSure Technolog…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…ABT logoABTAbbott Laboratori…
Beta (5Y)Sensitivity to S&P 5001.45x1.10x0.94x0.25x
52-Week HighHighest price in past year$3.82$643.99$242.80$139.06
52-Week LowLowest price in past year$2.08$385.46$172.06$86.15
% of 52W HighCurrent price vs 52-week peak+81.9%+73.7%+72.3%+62.6%
RSI (14)Momentum oscillator 0–10047.143.133.022.9
Avg Volume (50D)Average daily shares traded473K1.9M4.2M10.5M
Evenly matched — OSUR and ABT each lead in 1 of 2 comparable metrics.

Analyst Outlook

ABT leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: OSUR as "Hold", TMO as "Buy", DHR as "Buy", ABT as "Buy". Consensus price targets imply 47.9% upside for ABT (target: $129) vs 27.8% for OSUR (target: $4). For income investors, ABT offers the higher dividend yield at 2.52% vs TMO's 0.36%.

MetricOSUR logoOSUROraSure Technolog…TMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…ABT logoABTAbbott Laboratori…
Analyst RatingConsensus buy/hold/sellHoldBuyBuyBuy
Price TargetConsensus 12-month target$4.00$654.67$247.00$128.71
# AnalystsCovering analysts13424241
Dividend YieldAnnual dividend ÷ price+0.4%+0.7%+2.5%
Dividend StreakConsecutive years of raises28111
Dividend / ShareAnnual DPS$1.69$1.23$2.19
Buyback YieldShare repurchases ÷ mkt cap+6.7%+1.7%+2.5%+0.9%
ABT leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

ABT leads in 2 of 6 categories (Profitability & Efficiency, Analyst Outlook). DHR leads in 1 (Income & Cash Flow). 2 tied.

Best OverallAbbott Laboratories (ABT)Leads 2 of 6 categories
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OSUR vs TMO vs DHR vs ABT: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is OSUR or TMO or DHR or ABT a better buy right now?

For growth investors, Abbott Laboratories (ABT) is the stronger pick with 4.

6% revenue growth year-over-year, versus -38. 1% for OraSure Technologies, Inc. (OSUR). Abbott Laboratories (ABT) offers the better valuation at 11. 4x trailing P/E (15. 9x forward), making it the more compelling value choice. Analysts rate Thermo Fisher Scientific Inc. (TMO) a "Buy" — based on 42 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — OSUR or TMO or DHR or ABT?

On trailing P/E, Abbott Laboratories (ABT) is the cheapest at 11.

4x versus Danaher Corporation at 34. 9x. On forward P/E, Abbott Laboratories is actually cheaper at 15. 9x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Abbott Laboratories wins at 0. 53x versus Danaher Corporation's 34. 35x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — OSUR or TMO or DHR or ABT?

Over the past 5 years, Thermo Fisher Scientific Inc.

(TMO) delivered a total return of +2. 8%, compared to -68. 3% for OraSure Technologies, Inc. (OSUR). Over 10 years, the gap is even starker: TMO returned +229. 1% versus OSUR's -53. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — OSUR or TMO or DHR or ABT?

By beta (market sensitivity over 5 years), Abbott Laboratories (ABT) is the lower-risk stock at 0.

25β versus OraSure Technologies, Inc. 's 1. 45β — meaning OSUR is approximately 484% more volatile than ABT relative to the S&P 500. On balance sheet safety, OraSure Technologies, Inc. (OSUR) carries a lower debt/equity ratio of 4% versus 76% for Thermo Fisher Scientific Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — OSUR or TMO or DHR or ABT?

By revenue growth (latest reported year), Abbott Laboratories (ABT) is pulling ahead at 4.

6% versus -38. 1% for OraSure Technologies, Inc. (OSUR). On earnings-per-share growth, the picture is similar: Abbott Laboratories grew EPS 133. 6% year-over-year, compared to -261. 5% for OraSure Technologies, Inc.. Over a 3-year CAGR, TMO leads at -0. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — OSUR or TMO or DHR or ABT?

Abbott Laboratories (ABT) is the more profitable company, earning 31.

9% net margin versus -59. 8% for OraSure Technologies, Inc. — meaning it keeps 31. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DHR leads at 20. 9% versus -59. 2% for OSUR. At the gross margin level — before operating expenses — DHR leads at 60. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is OSUR or TMO or DHR or ABT more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Abbott Laboratories (ABT) is the more undervalued stock at a PEG of 0. 53x versus Danaher Corporation's 34. 35x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Abbott Laboratories (ABT) trades at 15. 9x forward P/E versus 20. 8x for Danaher Corporation — 4. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ABT: 47. 9% to $128. 71.

08

Which pays a better dividend — OSUR or TMO or DHR or ABT?

In this comparison, ABT (2.

5% yield), DHR (0. 7% yield), TMO (0. 4% yield) pay a dividend. OSUR does not pay a meaningful dividend and should not be held primarily for income.

09

Is OSUR or TMO or DHR or ABT better for a retirement portfolio?

For long-horizon retirement investors, Abbott Laboratories (ABT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

25), 2. 5% yield, +173. 7% 10Y return). Both have compounded well over 10 years (ABT: +173. 7%, OSUR: -53. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between OSUR and TMO and DHR and ABT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: OSUR is a small-cap quality compounder stock; TMO is a mid-cap quality compounder stock; DHR is a mid-cap quality compounder stock; ABT is a mid-cap deep-value stock. DHR, ABT pay a dividend while OSUR, TMO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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OSUR

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 23%
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  • Sector: Healthcare
  • Market Cap > $100B
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  • Dividend Yield > 0.5%
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ABT

Dividend Mega-Cap Quality

  • Sector: Healthcare
  • Market Cap > $100B
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Beat Both

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Revenue Growth>
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(OSUR: -99.9% · TMO: 6.2%)

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