Biotechnology
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5 / 10Stock Comparison
OTLK vs RCKT vs EDIT vs BEAM vs REGN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
OTLK vs RCKT vs EDIT vs BEAM vs REGN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $14M | $398M | $297M | $3.23B | $73.68B |
| Revenue (TTM) | $206K | $0.00 | $0.00 | $132M | $14.92B |
| Net Income (TTM) | $-103M | $-223M | $-160M | $-65M | $4.42B |
| Gross Margin | -5.9% | — | — | -64.2% | 84.5% |
| Operating Margin | -286.8% | — | — | -281.0% | 24.3% |
| Forward P/E | — | — | — | — | 15.3x |
| Total Debt | $247.70B | $25M | $18M | $294M | $2.71B |
| Cash & Equiv. | $8.08T | $78M | $147M | $295M | $3.12B |
OTLK vs RCKT vs EDIT vs BEAM vs REGN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Outlook Therapeutic… (OTLK) | 100 | 1.1 | -98.9% |
| Rocket Pharmaceutic… (RCKT) | 100 | 19.5 | -80.5% |
| Editas Medicine, In… (EDIT) | 100 | 11.2 | -88.8% |
| Beam Therapeutics I… (BEAM) | 100 | 123.2 | +23.2% |
| Regeneron Pharmaceu… (REGN) | 100 | 115.7 | +15.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: OTLK vs RCKT vs EDIT vs BEAM vs REGN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
OTLK is the clearest fit if your priority is income & stability.
- Dividend streak 2 yrs, beta 1.54
Among these 5 stocks, RCKT doesn't own a clear edge in any measured category.
EDIT is the #2 pick in this set and the best alternative if momentum is your priority.
- +127.8% vs OTLK's -84.7%
BEAM ranks third and is worth considering specifically for growth exposure.
- Rev growth 120.0%, EPS growth 82.3%, 3Y rev CAGR 31.9%
- 120.0% revenue growth vs EDIT's -100.0%
REGN carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.
- 90.0% 10Y total return vs BEAM's 67.8%
- Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
- Beta 0.81, yield 0.5%, current ratio 4.13x
- 29.6% margin vs OTLK's -500.5%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 120.0% revenue growth vs EDIT's -100.0% | |
| Quality / Margins | 29.6% margin vs OTLK's -500.5% | |
| Stability / Safety | Beta 0.81 vs EDIT's 2.52, lower leverage | |
| Dividends | 0.5% yield; 1-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +127.8% vs OTLK's -84.7% | |
| Efficiency (ROA) | 11.1% ROA vs EDIT's -74.2% |
OTLK vs RCKT vs EDIT vs BEAM vs REGN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
OTLK vs RCKT vs EDIT vs BEAM vs REGN — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
REGN leads in 3 of 6 categories
OTLK leads 1 • RCKT leads 0 • EDIT leads 0 • BEAM leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
REGN leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
REGN and EDIT operate at a comparable scale, with $14.9B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to OTLK's -500.5%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $205,535 | $0 | $0 | $132M | $14.9B |
| EBITDAEarnings before interest/tax | -$59M | -$232M | $0 | -$355M | $4.2B |
| Net IncomeAfter-tax profit | -$103M | -$223M | -$160M | -$65M | $4.4B |
| Free Cash FlowCash after capex | -$14.94T | -$190M | -$166M | -$384M | $4.2B |
| Gross MarginGross profit ÷ Revenue | -5.9% | — | — | -64.2% | +84.5% |
| Operating MarginEBIT ÷ Revenue | -286.8% | — | — | -2.8% | +24.3% |
| Net MarginNet income ÷ Revenue | -500.5% | — | — | -49.2% | +29.6% |
| FCF MarginFCF ÷ Revenue | -999999.0% | — | — | -2.9% | +27.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | -151.6% | -100.0% | +19.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -152.8% | +38.7% | +105.5% | +26.6% | -7.2% |
Valuation Metrics
Evenly matched — RCKT and BEAM and REGN each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $14M | $398M | $297M | $3.2B | $73.7B |
| Enterprise ValueMkt cap + debt − cash | -$7.84T | $345M | $168M | $3.2B | $73.3B |
| Trailing P/EPrice ÷ TTM EPS | -0.12x | -1.83x | -1.68x | -38.85x | 17.09x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | 15.35x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 2.70x |
| EV / EBITDAEnterprise value multiple | — | — | — | — | 17.78x |
| Price / SalesMarket cap ÷ Revenue | 9.85x | — | — | 23.14x | 5.14x |
| Price / BookPrice ÷ Book value/share | — | 1.47x | 9.85x | 2.51x | 2.46x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | 18.06x |
Profitability & Efficiency
REGN leads this category, winning 7 of 9 comparable metrics.
Profitability & Efficiency
REGN delivers a 14.3% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $-5 for EDIT. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 0.66x. On the Piotroski fundamental quality scale (0–9), REGN scores 5/9 vs EDIT's 1/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | — | -80.5% | -5.2% | -5.9% | +14.3% |
| ROA (TTM)Return on assets | -0.0% | -67.5% | -74.2% | -4.6% | +11.1% |
| ROICReturn on invested capital | — | -63.2% | — | -31.1% | +8.9% |
| ROCEReturn on capital employed | — | -58.9% | — | -33.3% | +10.2% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 1 | 1 | 4 | 5 |
| Debt / EquityFinancial leverage | — | 0.09x | 0.66x | 0.24x | 0.09x |
| Net DebtTotal debt minus cash | -$7.84T | -$53M | -$129M | -$1M | -$412M |
| Cash & Equiv.Liquid assets | $8.08T | $78M | $147M | $295M | $3.1B |
| Total DebtShort + long-term debt | $247.7B | $25M | $18M | $294M | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | -182.41x | — | — | 1.08x | 108.44x |
Total Returns (Dividends Reinvested)
REGN leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in REGN five years ago would be worth $14,365 today (with dividends reinvested), compared to $50 for OTLK. Over the past 12 months, EDIT leads with a +127.8% total return vs OTLK's -84.7%. The 3-year compound annual growth rate (CAGR) favors REGN at -1.7% vs OTLK's -78.9% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -67.3% | +6.1% | +47.8% | +16.0% | -8.5% |
| 1-Year ReturnPast 12 months | -84.7% | -45.2% | +127.8% | +93.9% | +27.1% |
| 3-Year ReturnCumulative with dividends | -99.1% | -82.8% | -68.5% | -5.6% | -5.1% |
| 5-Year ReturnCumulative with dividends | -99.5% | -91.6% | -91.1% | -55.6% | +43.6% |
| 10-Year ReturnCumulative with dividends | -100.0% | -91.3% | -90.0% | +67.8% | +90.0% |
| CAGR (3Y)Annualised 3-year return | -78.9% | -44.4% | -32.0% | -1.9% | -1.7% |
Risk & Volatility
Evenly matched — BEAM and REGN each lead in 1 of 2 comparable metrics.
Risk & Volatility
REGN is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BEAM currently trades 86.4% from its 52-week high vs OTLK's 6.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.54x | 1.31x | 2.52x | 2.14x | 0.81x |
| 52-Week HighHighest price in past year | $3.39 | $7.39 | $4.54 | $36.44 | $821.11 |
| 52-Week LowLowest price in past year | $0.16 | $2.19 | $1.29 | $15.35 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +6.4% | +49.7% | +66.7% | +86.4% | +86.4% |
| RSI (14)Momentum oscillator 0–100 | 40.7 | 54.4 | 57.5 | 60.9 | 44.9 |
| Avg Volume (50D)Average daily shares traded | 4.0M | 3.5M | 1.6M | 2.0M | 631K |
Analyst Outlook
OTLK leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: RCKT as "Buy", EDIT as "Buy", BEAM as "Buy", REGN as "Buy". Consensus price targets imply 98.0% upside for EDIT (target: $6) vs 22.1% for REGN (target: $866). REGN is the only dividend payer here at 0.48% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $5.00 | $6.00 | $40.83 | $865.68 |
| # AnalystsCovering analysts | — | 19 | 25 | 27 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +0.5% |
| Dividend StreakConsecutive years of raises | 2 | — | — | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | +5.4% |
REGN leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). OTLK leads in 1 (Analyst Outlook). 2 tied.
OTLK vs RCKT vs EDIT vs BEAM vs REGN: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is OTLK or RCKT or EDIT or BEAM or REGN a better buy right now?
For growth investors, Beam Therapeutics Inc.
(BEAM) is the stronger pick with 120. 0% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 1x trailing P/E (15. 3x forward), making it the more compelling value choice. Analysts rate Rocket Pharmaceuticals, Inc. (RCKT) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — OTLK or RCKT or EDIT or BEAM or REGN?
Over the past 5 years, Regeneron Pharmaceuticals, Inc.
(REGN) delivered a total return of +43. 6%, compared to -99. 5% for Outlook Therapeutics, Inc. (OTLK). Over 10 years, the gap is even starker: REGN returned +90. 0% versus OTLK's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — OTLK or RCKT or EDIT or BEAM or REGN?
By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc.
(REGN) is the lower-risk stock at 0. 81β versus Editas Medicine, Inc. 's 2. 52β — meaning EDIT is approximately 213% more volatile than REGN relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 66% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — OTLK or RCKT or EDIT or BEAM or REGN?
By revenue growth (latest reported year), Beam Therapeutics Inc.
(BEAM) is pulling ahead at 120. 0% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Beam Therapeutics Inc. grew EPS 82. 3% year-over-year, compared to 8. 2% for Regeneron Pharmaceuticals, Inc.. Over a 3-year CAGR, BEAM leads at 31. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — OTLK or RCKT or EDIT or BEAM or REGN?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus -44. 2% for Outlook Therapeutics, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: REGN leads at 24. 9% versus -47. 4% for OTLK. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is OTLK or RCKT or EDIT or BEAM or REGN more undervalued right now?
Analyst consensus price targets imply the most upside for EDIT: 98.
0% to $6. 00.
07Which pays a better dividend — OTLK or RCKT or EDIT or BEAM or REGN?
In this comparison, REGN (0.
5% yield) pays a dividend. OTLK, RCKT, EDIT, BEAM do not pay a meaningful dividend and should not be held primarily for income.
08Is OTLK or RCKT or EDIT or BEAM or REGN better for a retirement portfolio?
For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc.
(REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 81)). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (REGN: +90. 0%, EDIT: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between OTLK and RCKT and EDIT and BEAM and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: OTLK is a small-cap quality compounder stock; RCKT is a small-cap quality compounder stock; EDIT is a small-cap quality compounder stock; BEAM is a small-cap high-growth stock; REGN is a mid-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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