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OTLK vs RCKT vs EDIT vs BEAM vs REGN

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
OTLK
Outlook Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$14M
5Y Perf.-98.9%
RCKT
Rocket Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$398M
5Y Perf.-80.5%
EDIT
Editas Medicine, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$297M
5Y Perf.-88.8%
BEAM
Beam Therapeutics Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.23B
5Y Perf.+23.2%
REGN
Regeneron Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$73.68B
5Y Perf.+15.7%

OTLK vs RCKT vs EDIT vs BEAM vs REGN — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
OTLK logoOTLK
RCKT logoRCKT
EDIT logoEDIT
BEAM logoBEAM
REGN logoREGN
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$14M$398M$297M$3.23B$73.68B
Revenue (TTM)$206K$0.00$0.00$132M$14.92B
Net Income (TTM)$-103M$-223M$-160M$-65M$4.42B
Gross Margin-5.9%-64.2%84.5%
Operating Margin-286.8%-281.0%24.3%
Forward P/E15.3x
Total Debt$247.70B$25M$18M$294M$2.71B
Cash & Equiv.$8.08T$78M$147M$295M$3.12B

OTLK vs RCKT vs EDIT vs BEAM vs REGNLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

OTLK
RCKT
EDIT
BEAM
REGN
StockMay 20May 26Return
Outlook Therapeutic… (OTLK)1001.1-98.9%
Rocket Pharmaceutic… (RCKT)10019.5-80.5%
Editas Medicine, In… (EDIT)10011.2-88.8%
Beam Therapeutics I… (BEAM)100123.2+23.2%
Regeneron Pharmaceu… (REGN)100115.7+15.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: OTLK vs RCKT vs EDIT vs BEAM vs REGN

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: REGN leads in 4 of 6 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Editas Medicine, Inc. is the stronger pick specifically for recent price momentum and sentiment. BEAM also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
OTLK
Outlook Therapeutics, Inc.
The Income Pick

OTLK is the clearest fit if your priority is income & stability.

  • Dividend streak 2 yrs, beta 1.54
Best for: income & stability
RCKT
Rocket Pharmaceuticals, Inc.
The Healthcare Pick

Among these 5 stocks, RCKT doesn't own a clear edge in any measured category.

Best for: healthcare exposure
EDIT
Editas Medicine, Inc.
The Momentum Pick

EDIT is the #2 pick in this set and the best alternative if momentum is your priority.

  • +127.8% vs OTLK's -84.7%
Best for: momentum
BEAM
Beam Therapeutics Inc.
The Growth Play

BEAM ranks third and is worth considering specifically for growth exposure.

  • Rev growth 120.0%, EPS growth 82.3%, 3Y rev CAGR 31.9%
  • 120.0% revenue growth vs EDIT's -100.0%
Best for: growth exposure
REGN
Regeneron Pharmaceuticals, Inc.
The Long-Run Compounder

REGN carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.

  • 90.0% 10Y total return vs BEAM's 67.8%
  • Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
  • Beta 0.81, yield 0.5%, current ratio 4.13x
  • 29.6% margin vs OTLK's -500.5%
Best for: long-term compounding and sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthBEAM logoBEAM120.0% revenue growth vs EDIT's -100.0%
Quality / MarginsREGN logoREGN29.6% margin vs OTLK's -500.5%
Stability / SafetyREGN logoREGNBeta 0.81 vs EDIT's 2.52, lower leverage
DividendsREGN logoREGN0.5% yield; 1-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)EDIT logoEDIT+127.8% vs OTLK's -84.7%
Efficiency (ROA)REGN logoREGN11.1% ROA vs EDIT's -74.2%

OTLK vs RCKT vs EDIT vs BEAM vs REGN — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

OTLKOutlook Therapeutics, Inc.

Segment breakdown not available.

RCKTRocket Pharmaceuticals, Inc.

Segment breakdown not available.

EDITEditas Medicine, Inc.
FY 2025
Reportable Segment
100.0%$41M
BEAMBeam Therapeutics Inc.

Segment breakdown not available.

REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M

OTLK vs RCKT vs EDIT vs BEAM vs REGN — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLREGNLAGGINGBEAM

Income & Cash Flow (Last 12 Months)

REGN leads this category, winning 5 of 6 comparable metrics.

REGN and EDIT operate at a comparable scale, with $14.9B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to OTLK's -500.5%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricOTLK logoOTLKOutlook Therapeut…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …BEAM logoBEAMBeam Therapeutics…REGN logoREGNRegeneron Pharmac…
RevenueTrailing 12 months$205,535$0$0$132M$14.9B
EBITDAEarnings before interest/tax-$59M-$232M$0-$355M$4.2B
Net IncomeAfter-tax profit-$103M-$223M-$160M-$65M$4.4B
Free Cash FlowCash after capex-$14.94T-$190M-$166M-$384M$4.2B
Gross MarginGross profit ÷ Revenue-5.9%-64.2%+84.5%
Operating MarginEBIT ÷ Revenue-286.8%-2.8%+24.3%
Net MarginNet income ÷ Revenue-500.5%-49.2%+29.6%
FCF MarginFCF ÷ Revenue-999999.0%-2.9%+27.9%
Rev. Growth (YoY)Latest quarter vs prior year-151.6%-100.0%+19.0%
EPS Growth (YoY)Latest quarter vs prior year-152.8%+38.7%+105.5%+26.6%-7.2%
REGN leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

Evenly matched — RCKT and BEAM and REGN each lead in 1 of 3 comparable metrics.
MetricOTLK logoOTLKOutlook Therapeut…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …BEAM logoBEAMBeam Therapeutics…REGN logoREGNRegeneron Pharmac…
Market CapShares × price$14M$398M$297M$3.2B$73.7B
Enterprise ValueMkt cap + debt − cash-$7.84T$345M$168M$3.2B$73.3B
Trailing P/EPrice ÷ TTM EPS-0.12x-1.83x-1.68x-38.85x17.09x
Forward P/EPrice ÷ next-FY EPS est.15.35x
PEG RatioP/E ÷ EPS growth rate2.70x
EV / EBITDAEnterprise value multiple17.78x
Price / SalesMarket cap ÷ Revenue9.85x23.14x5.14x
Price / BookPrice ÷ Book value/share1.47x9.85x2.51x2.46x
Price / FCFMarket cap ÷ FCF18.06x
Evenly matched — RCKT and BEAM and REGN each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

REGN leads this category, winning 7 of 9 comparable metrics.

REGN delivers a 14.3% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $-5 for EDIT. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to EDIT's 0.66x. On the Piotroski fundamental quality scale (0–9), REGN scores 5/9 vs EDIT's 1/9, reflecting solid financial health.

MetricOTLK logoOTLKOutlook Therapeut…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …BEAM logoBEAMBeam Therapeutics…REGN logoREGNRegeneron Pharmac…
ROE (TTM)Return on equity-80.5%-5.2%-5.9%+14.3%
ROA (TTM)Return on assets-0.0%-67.5%-74.2%-4.6%+11.1%
ROICReturn on invested capital-63.2%-31.1%+8.9%
ROCEReturn on capital employed-58.9%-33.3%+10.2%
Piotroski ScoreFundamental quality 0–941145
Debt / EquityFinancial leverage0.09x0.66x0.24x0.09x
Net DebtTotal debt minus cash-$7.84T-$53M-$129M-$1M-$412M
Cash & Equiv.Liquid assets$8.08T$78M$147M$295M$3.1B
Total DebtShort + long-term debt$247.7B$25M$18M$294M$2.7B
Interest CoverageEBIT ÷ Interest expense-182.41x1.08x108.44x
REGN leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

REGN leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in REGN five years ago would be worth $14,365 today (with dividends reinvested), compared to $50 for OTLK. Over the past 12 months, EDIT leads with a +127.8% total return vs OTLK's -84.7%. The 3-year compound annual growth rate (CAGR) favors REGN at -1.7% vs OTLK's -78.9% — a key indicator of consistent wealth creation.

MetricOTLK logoOTLKOutlook Therapeut…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …BEAM logoBEAMBeam Therapeutics…REGN logoREGNRegeneron Pharmac…
YTD ReturnYear-to-date-67.3%+6.1%+47.8%+16.0%-8.5%
1-Year ReturnPast 12 months-84.7%-45.2%+127.8%+93.9%+27.1%
3-Year ReturnCumulative with dividends-99.1%-82.8%-68.5%-5.6%-5.1%
5-Year ReturnCumulative with dividends-99.5%-91.6%-91.1%-55.6%+43.6%
10-Year ReturnCumulative with dividends-100.0%-91.3%-90.0%+67.8%+90.0%
CAGR (3Y)Annualised 3-year return-78.9%-44.4%-32.0%-1.9%-1.7%
REGN leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — BEAM and REGN each lead in 1 of 2 comparable metrics.

REGN is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BEAM currently trades 86.4% from its 52-week high vs OTLK's 6.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricOTLK logoOTLKOutlook Therapeut…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …BEAM logoBEAMBeam Therapeutics…REGN logoREGNRegeneron Pharmac…
Beta (5Y)Sensitivity to S&P 5001.54x1.31x2.52x2.14x0.81x
52-Week HighHighest price in past year$3.39$7.39$4.54$36.44$821.11
52-Week LowLowest price in past year$0.16$2.19$1.29$15.35$476.49
% of 52W HighCurrent price vs 52-week peak+6.4%+49.7%+66.7%+86.4%+86.4%
RSI (14)Momentum oscillator 0–10040.754.457.560.944.9
Avg Volume (50D)Average daily shares traded4.0M3.5M1.6M2.0M631K
Evenly matched — BEAM and REGN each lead in 1 of 2 comparable metrics.

Analyst Outlook

OTLK leads this category, winning 1 of 1 comparable metric.

Analyst consensus: RCKT as "Buy", EDIT as "Buy", BEAM as "Buy", REGN as "Buy". Consensus price targets imply 98.0% upside for EDIT (target: $6) vs 22.1% for REGN (target: $866). REGN is the only dividend payer here at 0.48% yield — a key consideration for income-focused portfolios.

MetricOTLK logoOTLKOutlook Therapeut…RCKT logoRCKTRocket Pharmaceut…EDIT logoEDITEditas Medicine, …BEAM logoBEAMBeam Therapeutics…REGN logoREGNRegeneron Pharmac…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$5.00$6.00$40.83$865.68
# AnalystsCovering analysts19252748
Dividend YieldAnnual dividend ÷ price+0.5%
Dividend StreakConsecutive years of raises21
Dividend / ShareAnnual DPS$3.41
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+5.4%
OTLK leads this category, winning 1 of 1 comparable metric.
Key Takeaway

REGN leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). OTLK leads in 1 (Analyst Outlook). 2 tied.

Best OverallRegeneron Pharmaceuticals, … (REGN)Leads 3 of 6 categories
Loading custom metrics...

OTLK vs RCKT vs EDIT vs BEAM vs REGN: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is OTLK or RCKT or EDIT or BEAM or REGN a better buy right now?

For growth investors, Beam Therapeutics Inc.

(BEAM) is the stronger pick with 120. 0% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 1x trailing P/E (15. 3x forward), making it the more compelling value choice. Analysts rate Rocket Pharmaceuticals, Inc. (RCKT) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — OTLK or RCKT or EDIT or BEAM or REGN?

Over the past 5 years, Regeneron Pharmaceuticals, Inc.

(REGN) delivered a total return of +43. 6%, compared to -99. 5% for Outlook Therapeutics, Inc. (OTLK). Over 10 years, the gap is even starker: REGN returned +90. 0% versus OTLK's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — OTLK or RCKT or EDIT or BEAM or REGN?

By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc.

(REGN) is the lower-risk stock at 0. 81β versus Editas Medicine, Inc. 's 2. 52β — meaning EDIT is approximately 213% more volatile than REGN relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 66% for Editas Medicine, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — OTLK or RCKT or EDIT or BEAM or REGN?

By revenue growth (latest reported year), Beam Therapeutics Inc.

(BEAM) is pulling ahead at 120. 0% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Beam Therapeutics Inc. grew EPS 82. 3% year-over-year, compared to 8. 2% for Regeneron Pharmaceuticals, Inc.. Over a 3-year CAGR, BEAM leads at 31. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — OTLK or RCKT or EDIT or BEAM or REGN?

Regeneron Pharmaceuticals, Inc.

(REGN) is the more profitable company, earning 31. 4% net margin versus -44. 2% for Outlook Therapeutics, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: REGN leads at 24. 9% versus -47. 4% for OTLK. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is OTLK or RCKT or EDIT or BEAM or REGN more undervalued right now?

Analyst consensus price targets imply the most upside for EDIT: 98.

0% to $6. 00.

07

Which pays a better dividend — OTLK or RCKT or EDIT or BEAM or REGN?

In this comparison, REGN (0.

5% yield) pays a dividend. OTLK, RCKT, EDIT, BEAM do not pay a meaningful dividend and should not be held primarily for income.

08

Is OTLK or RCKT or EDIT or BEAM or REGN better for a retirement portfolio?

For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc.

(REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 81)). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (REGN: +90. 0%, EDIT: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between OTLK and RCKT and EDIT and BEAM and REGN?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: OTLK is a small-cap quality compounder stock; RCKT is a small-cap quality compounder stock; EDIT is a small-cap quality compounder stock; BEAM is a small-cap high-growth stock; REGN is a mid-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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OTLK

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  • Market Cap > $100B
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  • Market Cap > $100B
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  • Market Cap > $100B
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