Biotechnology
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PRTC vs ABSI vs RXRX vs BEAM
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
PRTC vs ABSI vs RXRX vs BEAM — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $41M | $894M | $1.46B | $3.23B |
| Revenue (TTM) | $9M | $2M | $66M | $132M |
| Net Income (TTM) | $-56M | $-118M | $-560M | $-65M |
| Gross Margin | -196.2% | -13.4% | -34.4% | -64.2% |
| Operating Margin | -26.2% | -60.3% | -8.8% | -281.0% |
| Total Debt | $20M | $5M | $78M | $294M |
| Cash & Equiv. | $254M | $20M | $743M | $295M |
PRTC vs ABSI vs RXRX vs BEAM — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 21 | May 26 | Return |
|---|---|---|---|
| PureTech Health plc (PRTC) | 100 | 35.9 | -64.1% |
| Absci Corporation (ABSI) | 100 | 20.7 | -79.3% |
| Recursion Pharmaceu… (RXRX) | 100 | 10.9 | -89.1% |
| Beam Therapeutics I… (BEAM) | 100 | 35.1 | -64.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: PRTC vs ABSI vs RXRX vs BEAM
Each card shows where this stock fits in a portfolio — not just who wins on paper.
PRTC is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.
- Dividend streak 1 yrs, beta 0.51
- Lower volatility, beta 0.51, Low D/E 6.5%, current ratio 6.59x
- Beta 0.51, current ratio 6.59x
- Beta 0.51 vs RXRX's 3.18, lower leverage
ABSI is the clearest fit if your priority is momentum.
- +116.2% vs RXRX's -22.0%
RXRX lags the leaders in this set but could rank higher in a more targeted comparison.
BEAM carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 120.0%, EPS growth 82.3%, 3Y rev CAGR 31.9%
- 67.8% 10Y total return vs PRTC's -55.9%
- 120.0% revenue growth vs ABSI's -38.2%
- -49.2% margin vs ABSI's -73.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 120.0% revenue growth vs ABSI's -38.2% | |
| Quality / Margins | -49.2% margin vs ABSI's -73.1% | |
| Stability / Safety | Beta 0.51 vs RXRX's 3.18, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +116.2% vs RXRX's -22.0% | |
| Efficiency (ROA) | -4.6% ROA vs ABSI's -54.7%, ROIC -31.1% vs -58.0% |
PRTC vs ABSI vs RXRX vs BEAM — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
PRTC vs ABSI vs RXRX vs BEAM — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
BEAM leads in 2 of 6 categories
PRTC leads 1 • ABSI leads 1 • RXRX leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
BEAM leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BEAM is the larger business by revenue, generating $132M annually — 81.6x ABSI's $2M. BEAM is the more profitable business, keeping -49.2% of every revenue dollar as net income compared to ABSI's -73.1%. On growth, PRTC holds the edge at -30.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $9M | $2M | $66M | $132M |
| EBITDAEarnings before interest/tax | -$228M | -$116M | -$521M | -$355M |
| Net IncomeAfter-tax profit | -$56M | -$118M | -$560M | -$65M |
| Free Cash FlowCash after capex | -$219M | -$99M | -$326M | -$384M |
| Gross MarginGross profit ÷ Revenue | -196.2% | -13.4% | -34.4% | -64.2% |
| Operating MarginEBIT ÷ Revenue | -26.2% | -60.3% | -8.8% | -2.8% |
| Net MarginNet income ÷ Revenue | -6.2% | -73.1% | -8.4% | -49.2% |
| FCF MarginFCF ÷ Revenue | -24.4% | -60.8% | -4.9% | -2.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | -30.5% | -100.0% | -56.1% | -100.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -8.7% | +9.5% | +56.0% | +26.6% |
Valuation Metrics
PRTC leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $41M | $894M | $1.5B | $3.2B |
| Enterprise ValueMkt cap + debt − cash | -$193M | $879M | $797M | $3.2B |
| Trailing P/EPrice ÷ TTM EPS | -0.37x | -6.85x | -2.27x | -38.85x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 8.79x | 319.22x | 19.58x | 23.14x |
| Price / BookPrice ÷ Book value/share | 0.13x | 4.15x | 1.29x | 2.51x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
BEAM leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
BEAM delivers a -5.9% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-64 for ABSI. ABSI carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to BEAM's 0.24x. On the Piotroski fundamental quality scale (0–9), PRTC scores 5/9 vs BEAM's 4/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -16.1% | -63.6% | -54.3% | -5.9% |
| ROA (TTM)Return on assets | -9.9% | -54.7% | -40.6% | -4.6% |
| ROICReturn on invested capital | -66.9% | -58.0% | -95.8% | -31.1% |
| ROCEReturn on capital employed | -18.8% | -65.9% | -50.1% | -33.3% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.06x | 0.03x | 0.07x | 0.24x |
| Net DebtTotal debt minus cash | -$234M | -$15M | -$665M | -$1M |
| Cash & Equiv.Liquid assets | $254M | $20M | $743M | $295M |
| Total DebtShort + long-term debt | $20M | $5M | $78M | $294M |
| Interest CoverageEBIT ÷ Interest expense | -1.16x | -865.97x | -336.46x | 1.08x |
Total Returns (Dividends Reinvested)
ABSI leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in BEAM five years ago would be worth $4,444 today (with dividends reinvested), compared to $1,179 for RXRX. Over the past 12 months, ABSI leads with a +116.2% total return vs RXRX's -22.0%. The 3-year compound annual growth rate (CAGR) favors ABSI at 59.4% vs RXRX's -16.4% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +2.0% | +59.3% | -22.1% | +16.0% |
| 1-Year ReturnPast 12 months | -2.6% | +116.2% | -22.0% | +93.9% |
| 3-Year ReturnCumulative with dividends | -41.3% | +304.9% | -41.6% | -5.6% |
| 5-Year ReturnCumulative with dividends | -70.1% | -73.4% | -88.2% | -55.6% |
| 10-Year ReturnCumulative with dividends | -55.9% | -73.4% | -81.8% | +67.8% |
| CAGR (3Y)Annualised 3-year return | -16.3% | +59.4% | -16.4% | -1.9% |
Risk & Volatility
Evenly matched — PRTC and ABSI each lead in 1 of 2 comparable metrics.
Risk & Volatility
PRTC is the less volatile stock with a 0.51 beta — it tends to amplify market swings less than RXRX's 3.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ABSI currently trades 92.2% from its 52-week high vs RXRX's 45.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.51x | 2.77x | 2.99x | 2.08x |
| 52-Week HighHighest price in past year | $19.92 | $6.24 | $7.18 | $36.44 |
| 52-Week LowLowest price in past year | $14.50 | $2.24 | $2.80 | $15.35 |
| % of 52W HighCurrent price vs 52-week peak | +85.2% | +92.2% | +45.5% | +86.4% |
| RSI (14)Momentum oscillator 0–100 | 48.2 | 83.6 | 49.5 | 60.9 |
| Avg Volume (50D)Average daily shares traded | 8K | 4.4M | 12.5M | 2.0M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: PRTC as "Buy", ABSI as "Buy", RXRX as "Hold", BEAM as "Buy". Consensus price targets imply 236.4% upside for RXRX (target: $11) vs 7.1% for ABSI (target: $6).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | $57.00 | $6.16 | $11.00 | $40.83 |
| # AnalystsCovering analysts | 2 | 12 | 10 | 27 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | 1 | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +5.0% | 0.0% | 0.0% | 0.0% |
BEAM leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PRTC leads in 1 (Valuation Metrics). 1 tied.
PRTC vs ABSI vs RXRX vs BEAM: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is PRTC or ABSI or RXRX or BEAM a better buy right now?
For growth investors, Beam Therapeutics Inc.
(BEAM) is the stronger pick with 120. 0% revenue growth year-over-year, versus -38. 2% for Absci Corporation (ABSI). Analysts rate PureTech Health plc (PRTC) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — PRTC or ABSI or RXRX or BEAM?
Over the past 5 years, Beam Therapeutics Inc.
(BEAM) delivered a total return of -55. 6%, compared to -88. 2% for Recursion Pharmaceuticals, Inc. (RXRX). Over 10 years, the gap is even starker: BEAM returned +72. 4% versus RXRX's -81. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — PRTC or ABSI or RXRX or BEAM?
By beta (market sensitivity over 5 years), PureTech Health plc (PRTC) is the lower-risk stock at 0.
51β versus Recursion Pharmaceuticals, Inc. 's 2. 99β — meaning RXRX is approximately 485% more volatile than PRTC relative to the S&P 500. On balance sheet safety, Absci Corporation (ABSI) carries a lower debt/equity ratio of 3% versus 24% for Beam Therapeutics Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — PRTC or ABSI or RXRX or BEAM?
By revenue growth (latest reported year), Beam Therapeutics Inc.
(BEAM) is pulling ahead at 120. 0% versus -38. 2% for Absci Corporation (ABSI). On earnings-per-share growth, the picture is similar: Beam Therapeutics Inc. grew EPS 82. 3% year-over-year, compared to -24. 0% for PureTech Health plc. Over a 3-year CAGR, BEAM leads at 31. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — PRTC or ABSI or RXRX or BEAM?
Beam Therapeutics Inc.
(BEAM) is the more profitable company, earning -57. 2% net margin versus -41. 1% for Absci Corporation — meaning it keeps -57. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BEAM leads at -274. 6% versus -44. 5% for ABSI. At the gross margin level — before operating expenses — PRTC leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — PRTC or ABSI or RXRX or BEAM?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is PRTC or ABSI or RXRX or BEAM better for a retirement portfolio?
For long-horizon retirement investors, PureTech Health plc (PRTC) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
51)). Recursion Pharmaceuticals, Inc. (RXRX) carries a higher beta of 2. 99 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PRTC: -55. 5%, RXRX: -81. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between PRTC and ABSI and RXRX and BEAM?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: PRTC is a small-cap quality compounder stock; ABSI is a small-cap quality compounder stock; RXRX is a small-cap high-growth stock; BEAM is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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