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PRTC vs ROIV vs RXRX vs ABBV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
PRTC
PureTech Health plc

Biotechnology

HealthcareNASDAQ • US
Market Cap$41M
5Y Perf.-70.1%
ROIV
Roivant Sciences Ltd.

Biotechnology

HealthcareNASDAQ • GB
Market Cap$20.51B
5Y Perf.+186.8%
RXRX
Recursion Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.46B
5Y Perf.-90.2%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$358.42B
5Y Perf.+81.7%

PRTC vs ROIV vs RXRX vs ABBV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
PRTC logoPRTC
ROIV logoROIV
RXRX logoRXRX
ABBV logoABBV
IndustryBiotechnologyBiotechnologyBiotechnologyDrug Manufacturers - General
Market Cap$41M$20.51B$1.46B$358.42B
Revenue (TTM)$9M$13M$66M$61.16B
Net Income (TTM)$-56M$-809M$-560M$4.23B
Gross Margin-196.2%91.2%-34.4%70.2%
Operating Margin-26.2%-91.3%-8.8%26.7%
Forward P/E14.3x
Total Debt$20M$100M$78M$69.07B
Cash & Equiv.$254M$2.72B$743M$5.23B

PRTC vs ROIV vs RXRX vs ABBVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

PRTC
ROIV
RXRX
ABBV
StockApr 21May 26Return
PureTech Health plc (PRTC)10029.9-70.1%
Roivant Sciences Lt… (ROIV)100286.8+186.8%
Recursion Pharmaceu… (RXRX)1009.8-90.2%
AbbVie Inc. (ABBV)100181.7+81.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: PRTC vs ROIV vs RXRX vs ABBV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABBV leads in 4 of 6 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Roivant Sciences Ltd. is the stronger pick specifically for recent price momentum and sentiment. RXRX also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
PRTC
PureTech Health plc
The Defensive Pick

PRTC is the clearest fit if your priority is defensive.

  • Beta 0.51, current ratio 6.59x
Best for: defensive
ROIV
Roivant Sciences Ltd.
The Defensive Pick

ROIV is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.

  • Lower volatility, beta 0.95, Low D/E 1.9%, current ratio 33.47x
  • +153.2% vs RXRX's -22.0%
Best for: sleep-well-at-night
RXRX
Recursion Pharmaceuticals, Inc.
The Growth Play

RXRX is the clearest fit if your priority is growth exposure.

  • Rev growth 26.9%, EPS growth 14.8%, 3Y rev CAGR 23.5%
  • 26.9% revenue growth vs ROIV's -11.2%
Best for: growth exposure
ABBV
AbbVie Inc.
The Income Pick

ABBV carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 13 yrs, beta 0.34, yield 3.2%
  • 295.5% 10Y total return vs ROIV's 171.9%
  • 6.9% margin vs ROIV's -60.8%
  • Beta 0.34 vs RXRX's 3.18
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthRXRX logoRXRX26.9% revenue growth vs ROIV's -11.2%
Quality / MarginsABBV logoABBV6.9% margin vs ROIV's -60.8%
Stability / SafetyABBV logoABBVBeta 0.34 vs RXRX's 3.18
DividendsABBV logoABBV3.2% yield; 13-year raise streak; the other 3 pay no meaningful dividend
Momentum (1Y)ROIV logoROIV+153.2% vs RXRX's -22.0%
Efficiency (ROA)ABBV logoABBV3.1% ROA vs RXRX's -40.6%, ROIC 23.9% vs -95.8%

PRTC vs ROIV vs RXRX vs ABBV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

PRTCPureTech Health plc

Segment breakdown not available.

ROIVRoivant Sciences Ltd.
FY 2024
Product
100.0%$75M
RXRXRecursion Pharmaceuticals, Inc.
FY 2025
License and Service
99.4%$74M
Grant
0.6%$425,000
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B

PRTC vs ROIV vs RXRX vs ABBV — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLABBVLAGGINGRXRX

Income & Cash Flow (Last 12 Months)

ABBV leads this category, winning 5 of 6 comparable metrics.

ABBV is the larger business by revenue, generating $61.2B annually — 6823.3x PRTC's $9M. ABBV is the more profitable business, keeping 6.9% of every revenue dollar as net income compared to ROIV's -60.8%. On growth, ABBV holds the edge at +10.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricPRTC logoPRTCPureTech Health p…ROIV logoROIVRoivant Sciences …RXRX logoRXRXRecursion Pharmac…ABBV logoABBVAbbVie Inc.
RevenueTrailing 12 months$9M$13M$66M$61.2B
EBITDAEarnings before interest/tax-$228M-$1.2B-$521M$24.5B
Net IncomeAfter-tax profit-$56M-$809M-$560M$4.2B
Free Cash FlowCash after capex-$219M-$767M-$326M$18.7B
Gross MarginGross profit ÷ Revenue-196.2%+91.2%-34.4%+70.2%
Operating MarginEBIT ÷ Revenue-26.2%-91.3%-8.8%+26.7%
Net MarginNet income ÷ Revenue-6.2%-60.8%-8.4%+6.9%
FCF MarginFCF ÷ Revenue-24.4%-57.6%-4.9%+30.6%
Rev. Growth (YoY)Latest quarter vs prior year-30.5%-77.8%-56.1%+10.0%
EPS Growth (YoY)Latest quarter vs prior year-8.7%-2.7%+56.0%+57.4%
ABBV leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

Evenly matched — PRTC and ROIV and ABBV each lead in 1 of 3 comparable metrics.
MetricPRTC logoPRTCPureTech Health p…ROIV logoROIVRoivant Sciences …RXRX logoRXRXRecursion Pharmac…ABBV logoABBVAbbVie Inc.
Market CapShares × price$41M$20.5B$1.5B$358.4B
Enterprise ValueMkt cap + debt − cash-$193M$17.9B$797M$422.3B
Trailing P/EPrice ÷ TTM EPS-0.37x-117.83x-2.27x85.50x
Forward P/EPrice ÷ next-FY EPS est.14.28x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple14.96x
Price / SalesMarket cap ÷ Revenue8.79x706.10x19.58x5.86x
Price / BookPrice ÷ Book value/share0.13x3.95x1.29x
Price / FCFMarket cap ÷ FCF20.12x
Evenly matched — PRTC and ROIV and ABBV each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

ABBV leads this category, winning 6 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-54 for RXRX. ROIV carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to RXRX's 0.07x. On the Piotroski fundamental quality scale (0–9), ABBV scores 6/9 vs RXRX's 4/9, reflecting solid financial health.

MetricPRTC logoPRTCPureTech Health p…ROIV logoROIVRoivant Sciences …RXRX logoRXRXRecursion Pharmac…ABBV logoABBVAbbVie Inc.
ROE (TTM)Return on equity-16.1%-16.3%-54.3%+62.1%
ROA (TTM)Return on assets-9.9%-15.5%-40.6%+3.1%
ROICReturn on invested capital-66.9%-50.4%-95.8%+23.9%
ROCEReturn on capital employed-18.8%-16.4%-50.1%+21.5%
Piotroski ScoreFundamental quality 0–95546
Debt / EquityFinancial leverage0.06x0.02x0.07x
Net DebtTotal debt minus cash-$234M-$2.6B-$665M$63.8B
Cash & Equiv.Liquid assets$254M$2.7B$743M$5.2B
Total DebtShort + long-term debt$20M$100M$78M$69.1B
Interest CoverageEBIT ÷ Interest expense-1.16x-336.46x3.28x
ABBV leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ROIV leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in ROIV five years ago would be worth $28,537 today (with dividends reinvested), compared to $1,179 for RXRX. Over the past 12 months, ROIV leads with a +153.2% total return vs RXRX's -22.0%. The 3-year compound annual growth rate (CAGR) favors ROIV at 46.7% vs RXRX's -16.4% — a key indicator of consistent wealth creation.

MetricPRTC logoPRTCPureTech Health p…ROIV logoROIVRoivant Sciences …RXRX logoRXRXRecursion Pharmac…ABBV logoABBVAbbVie Inc.
YTD ReturnYear-to-date+2.0%+29.0%-22.1%-10.1%
1-Year ReturnPast 12 months-2.6%+153.2%-22.0%+11.3%
3-Year ReturnCumulative with dividends-41.3%+215.6%-41.6%+50.4%
5-Year ReturnCumulative with dividends-70.1%+185.4%-88.2%+101.3%
10-Year ReturnCumulative with dividends-55.9%+171.9%-81.8%+295.5%
CAGR (3Y)Annualised 3-year return-16.3%+46.7%-16.4%+14.6%
ROIV leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ROIV and ABBV each lead in 1 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than RXRX's 3.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ROIV currently trades 93.2% from its 52-week high vs RXRX's 45.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricPRTC logoPRTCPureTech Health p…ROIV logoROIVRoivant Sciences …RXRX logoRXRXRecursion Pharmac…ABBV logoABBVAbbVie Inc.
Beta (5Y)Sensitivity to S&P 5000.51x0.95x3.18x0.34x
52-Week HighHighest price in past year$19.92$30.33$7.18$244.81
52-Week LowLowest price in past year$14.50$10.58$2.80$176.57
% of 52W HighCurrent price vs 52-week peak+85.2%+93.2%+45.5%+82.8%
RSI (14)Momentum oscillator 0–10048.254.849.546.8
Avg Volume (50D)Average daily shares traded8K4.8M12.5M5.8M
Evenly matched — ROIV and ABBV each lead in 1 of 2 comparable metrics.

Analyst Outlook

ABBV leads this category, winning 1 of 1 comparable metric.

Analyst consensus: PRTC as "Buy", ROIV as "Buy", RXRX as "Hold", ABBV as "Buy". Consensus price targets imply 236.4% upside for RXRX (target: $11) vs 17.4% for ROIV (target: $33). ABBV is the only dividend payer here at 3.24% yield — a key consideration for income-focused portfolios.

MetricPRTC logoPRTCPureTech Health p…ROIV logoROIVRoivant Sciences …RXRX logoRXRXRecursion Pharmac…ABBV logoABBVAbbVie Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuy
Price TargetConsensus 12-month target$57.00$33.20$11.00$256.64
# AnalystsCovering analysts2141041
Dividend YieldAnnual dividend ÷ price+3.2%
Dividend StreakConsecutive years of raises1113
Dividend / ShareAnnual DPS$6.57
Buyback YieldShare repurchases ÷ mkt cap+5.0%+6.3%0.0%+0.3%
ABBV leads this category, winning 1 of 1 comparable metric.
Key Takeaway

ABBV leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). ROIV leads in 1 (Total Returns). 2 tied.

Best OverallAbbVie Inc. (ABBV)Leads 3 of 6 categories
Loading custom metrics...

PRTC vs ROIV vs RXRX vs ABBV: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is PRTC or ROIV or RXRX or ABBV a better buy right now?

For growth investors, Recursion Pharmaceuticals, Inc.

(RXRX) is the stronger pick with 26. 9% revenue growth year-over-year, versus -11. 2% for Roivant Sciences Ltd. (ROIV). AbbVie Inc. (ABBV) offers the better valuation at 85. 5x trailing P/E (14. 3x forward), making it the more compelling value choice. Analysts rate PureTech Health plc (PRTC) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — PRTC or ROIV or RXRX or ABBV?

Over the past 5 years, Roivant Sciences Ltd.

(ROIV) delivered a total return of +185. 4%, compared to -88. 2% for Recursion Pharmaceuticals, Inc. (RXRX). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus RXRX's -81. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — PRTC or ROIV or RXRX or ABBV?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 34β versus Recursion Pharmaceuticals, Inc. 's 3. 18β — meaning RXRX is approximately 839% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Roivant Sciences Ltd. (ROIV) carries a lower debt/equity ratio of 2% versus 7% for Recursion Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — PRTC or ROIV or RXRX or ABBV?

By revenue growth (latest reported year), Recursion Pharmaceuticals, Inc.

(RXRX) is pulling ahead at 26. 9% versus -11. 2% for Roivant Sciences Ltd. (ROIV). On earnings-per-share growth, the picture is similar: Recursion Pharmaceuticals, Inc. grew EPS 14. 8% year-over-year, compared to -24. 0% for PureTech Health plc. Over a 3-year CAGR, PRTC leads at 30. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — PRTC or ROIV or RXRX or ABBV?

AbbVie Inc.

(ABBV) is the more profitable company, earning 6. 9% net margin versus -23. 6% for PureTech Health plc — meaning it keeps 6. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus -34. 5% for ROIV. At the gross margin level — before operating expenses — PRTC leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is PRTC or ROIV or RXRX or ABBV more undervalued right now?

Analyst consensus price targets imply the most upside for RXRX: 236.

4% to $11. 00.

07

Which pays a better dividend — PRTC or ROIV or RXRX or ABBV?

In this comparison, ABBV (3.

2% yield) pays a dividend. PRTC, ROIV, RXRX do not pay a meaningful dividend and should not be held primarily for income.

08

Is PRTC or ROIV or RXRX or ABBV better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Recursion Pharmaceuticals, Inc. (RXRX) carries a higher beta of 3. 18 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABBV: +295. 5%, RXRX: -81. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between PRTC and ROIV and RXRX and ABBV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: PRTC is a small-cap quality compounder stock; ROIV is a mid-cap quality compounder stock; RXRX is a small-cap high-growth stock; ABBV is a large-cap income-oriented stock. ABBV pays a dividend while PRTC, ROIV, RXRX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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