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Stock Comparison

QGEN vs NTRA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
QGEN
Qiagen N.V.

Medical - Diagnostics & Research

HealthcareNYSE • NL
Market Cap$6.91B
5Y Perf.-27.8%
NTRA
Natera, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$31.16B
5Y Perf.+401.3%

QGEN vs NTRA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
QGEN logoQGEN
NTRA logoNTRA
IndustryMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$6.91B$31.16B
Revenue (TTM)$2.09B$2.31B
Net Income (TTM)$425M$-208M
Gross Margin61.8%64.8%
Operating Margin24.9%-13.4%
Forward P/E13.4x
Total Debt$1.65B$214M
Cash & Equiv.$839M$1.08B

QGEN vs NTRALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

QGEN
NTRA
StockMay 20May 26Return
Qiagen N.V. (QGEN)10072.2-27.8%
Natera, Inc. (NTRA)100501.3+401.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: QGEN vs NTRA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: QGEN leads in 5 of 7 categories, making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Natera, Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
QGEN
Qiagen N.V.
The Income Pick

QGEN carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.

  • Dividend streak 1 yrs, beta 0.42, yield 0.8%
  • Lower volatility, beta 0.42, Low D/E 43.8%, current ratio 3.90x
  • Beta 0.42, yield 0.8%, current ratio 3.90x
Best for: income & stability and sleep-well-at-night
NTRA
Natera, Inc.
The Growth Play

NTRA is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth 35.9%, EPS growth 0.7%, 3Y rev CAGR 41.1%
  • 20.9% 10Y total return vs QGEN's 65.1%
  • 35.9% revenue growth vs QGEN's 5.7%
Best for: growth exposure and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthNTRA logoNTRA35.9% revenue growth vs QGEN's 5.7%
ValueQGEN logoQGENBetter valuation composite
Quality / MarginsQGEN logoQGEN20.3% margin vs NTRA's -9.0%
Stability / SafetyQGEN logoQGENBeta 0.42 vs NTRA's 1.26
DividendsQGEN logoQGEN0.8% yield; 1-year raise streak; the other pay no meaningful dividend
Momentum (1Y)NTRA logoNTRA+37.3% vs QGEN's -15.4%
Efficiency (ROA)QGEN logoQGEN7.0% ROA vs NTRA's -10.6%, ROIC 8.6% vs -36.1%

QGEN vs NTRA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

QGENQiagen N.V.
FY 2025
Consumables and Related
44.9%$1.9B
Diagnostic Solutions
19.2%$803M
Sample Technologies
15.8%$661M
PCR / Nucleic Acid Amplification
7.4%$309M
Genomics / NGS
5.8%$242M
Instruments
5.1%$214M
Product and Service, Other
1.8%$75M
NTRANatera, Inc.
FY 2025
Product
99.6%$2.3B
Licensing and other
0.4%$10M

QGEN vs NTRA — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLQGENLAGGINGNTRA

Income & Cash Flow (Last 12 Months)

Evenly matched — QGEN and NTRA each lead in 3 of 6 comparable metrics.

NTRA and QGEN operate at a comparable scale, with $2.3B and $2.1B in trailing revenue. QGEN is the more profitable business, keeping 20.3% of every revenue dollar as net income compared to NTRA's -9.0%. On growth, NTRA holds the edge at +39.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricQGEN logoQGENQiagen N.V.NTRA logoNTRANatera, Inc.
RevenueTrailing 12 months$2.1B$2.3B
EBITDAEarnings before interest/tax$714M-$310M
Net IncomeAfter-tax profit$425M-$208M
Free Cash FlowCash after capex$453M$97M
Gross MarginGross profit ÷ Revenue+61.8%+64.8%
Operating MarginEBIT ÷ Revenue+24.9%-13.4%
Net MarginNet income ÷ Revenue+20.3%-9.0%
FCF MarginFCF ÷ Revenue+21.7%+4.2%
Rev. Growth (YoY)Latest quarter vs prior year+3.7%+39.8%
EPS Growth (YoY)Latest quarter vs prior year+26.8%+185.4%
Evenly matched — QGEN and NTRA each lead in 3 of 6 comparable metrics.

Valuation Metrics

QGEN leads this category, winning 3 of 4 comparable metrics.
MetricQGEN logoQGENQiagen N.V.NTRA logoNTRANatera, Inc.
Market CapShares × price$6.9B$31.2B
Enterprise ValueMkt cap + debt − cash$7.7B$30.3B
Trailing P/EPrice ÷ TTM EPS16.44x-144.62x
Forward P/EPrice ÷ next-FY EPS est.13.42x
PEG RatioP/E ÷ EPS growth rate0.37x
EV / EBITDAEnterprise value multiple10.82x
Price / SalesMarket cap ÷ Revenue3.31x13.51x
Price / BookPrice ÷ Book value/share1.85x17.55x
Price / FCFMarket cap ÷ FCF15.24x285.53x
QGEN leads this category, winning 3 of 4 comparable metrics.

Profitability & Efficiency

QGEN leads this category, winning 6 of 9 comparable metrics.

QGEN delivers a 11.9% return on equity — every $100 of shareholder capital generates $12 in annual profit, vs $-15 for NTRA. NTRA carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to QGEN's 0.44x. On the Piotroski fundamental quality scale (0–9), QGEN scores 8/9 vs NTRA's 5/9, reflecting strong financial health.

MetricQGEN logoQGENQiagen N.V.NTRA logoNTRANatera, Inc.
ROE (TTM)Return on equity+11.9%-15.3%
ROA (TTM)Return on assets+7.0%-10.6%
ROICReturn on invested capital+8.6%-36.1%
ROCEReturn on capital employed+9.5%-18.3%
Piotroski ScoreFundamental quality 0–985
Debt / EquityFinancial leverage0.44x0.13x
Net DebtTotal debt minus cash$815M-$862M
Cash & Equiv.Liquid assets$839M$1.1B
Total DebtShort + long-term debt$1.7B$214M
Interest CoverageEBIT ÷ Interest expense15.74x-25.21x
QGEN leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NTRA leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in NTRA five years ago would be worth $21,587 today (with dividends reinvested), compared to $7,665 for QGEN. Over the past 12 months, NTRA leads with a +37.3% total return vs QGEN's -15.4%. The 3-year compound annual growth rate (CAGR) favors NTRA at 60.6% vs QGEN's -7.5% — a key indicator of consistent wealth creation.

MetricQGEN logoQGENQiagen N.V.NTRA logoNTRANatera, Inc.
YTD ReturnYear-to-date-20.7%-3.9%
1-Year ReturnPast 12 months-15.4%+37.3%
3-Year ReturnCumulative with dividends-20.7%+314.0%
5-Year ReturnCumulative with dividends-23.3%+115.9%
10-Year ReturnCumulative with dividends+65.1%+2089.4%
CAGR (3Y)Annualised 3-year return-7.5%+60.6%
NTRA leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — QGEN and NTRA each lead in 1 of 2 comparable metrics.

QGEN is the less volatile stock with a 0.42 beta — it tends to amplify market swings less than NTRA's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NTRA currently trades 85.7% from its 52-week high vs QGEN's 58.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricQGEN logoQGENQiagen N.V.NTRA logoNTRANatera, Inc.
Beta (5Y)Sensitivity to S&P 5000.42x1.26x
52-Week HighHighest price in past year$57.82$256.36
52-Week LowLowest price in past year$33.17$131.81
% of 52W HighCurrent price vs 52-week peak+58.0%+85.7%
RSI (14)Momentum oscillator 0–10029.357.1
Avg Volume (50D)Average daily shares traded1.9M1.3M
Evenly matched — QGEN and NTRA each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates QGEN as "Hold" and NTRA as "Buy". Consensus price targets imply 41.7% upside for QGEN (target: $48) vs 19.4% for NTRA (target: $263). QGEN is the only dividend payer here at 0.78% yield — a key consideration for income-focused portfolios.

MetricQGEN logoQGENQiagen N.V.NTRA logoNTRANatera, Inc.
Analyst RatingConsensus buy/hold/sellHoldBuy
Price TargetConsensus 12-month target$47.50$262.50
# AnalystsCovering analysts2927
Dividend YieldAnnual dividend ÷ price+0.8%
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS$0.26
Buyback YieldShare repurchases ÷ mkt cap+4.4%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

QGEN leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). NTRA leads in 1 (Total Returns). 2 tied.

Best OverallQiagen N.V. (QGEN)Leads 2 of 6 categories
Loading custom metrics...

QGEN vs NTRA: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is QGEN or NTRA a better buy right now?

For growth investors, Natera, Inc.

(NTRA) is the stronger pick with 35. 9% revenue growth year-over-year, versus 5. 7% for Qiagen N. V. (QGEN). Qiagen N. V. (QGEN) offers the better valuation at 16. 4x trailing P/E (13. 4x forward), making it the more compelling value choice. Analysts rate Natera, Inc. (NTRA) a "Buy" — based on 27 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — QGEN or NTRA?

Over the past 5 years, Natera, Inc.

(NTRA) delivered a total return of +115. 9%, compared to -23. 3% for Qiagen N. V. (QGEN). Over 10 years, the gap is even starker: NTRA returned +20. 9% versus QGEN's +65. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — QGEN or NTRA?

By beta (market sensitivity over 5 years), Qiagen N.

V. (QGEN) is the lower-risk stock at 0. 42β versus Natera, Inc. 's 1. 26β — meaning NTRA is approximately 201% more volatile than QGEN relative to the S&P 500. On balance sheet safety, Natera, Inc. (NTRA) carries a lower debt/equity ratio of 13% versus 44% for Qiagen N. V. — giving it more financial flexibility in a downturn.

04

Which is growing faster — QGEN or NTRA?

By revenue growth (latest reported year), Natera, Inc.

(NTRA) is pulling ahead at 35. 9% versus 5. 7% for Qiagen N. V. (QGEN). On earnings-per-share growth, the picture is similar: Qiagen N. V. grew EPS 436. 8% year-over-year, compared to 0. 7% for Natera, Inc.. Over a 3-year CAGR, NTRA leads at 41. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — QGEN or NTRA?

Qiagen N.

V. (QGEN) is the more profitable company, earning 20. 3% net margin versus -9. 0% for Natera, Inc. — meaning it keeps 20. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: QGEN leads at 24. 9% versus -13. 4% for NTRA. At the gross margin level — before operating expenses — NTRA leads at 64. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is QGEN or NTRA more undervalued right now?

Analyst consensus price targets imply the most upside for QGEN: 41.

7% to $47. 50.

07

Which pays a better dividend — QGEN or NTRA?

In this comparison, QGEN (0.

8% yield) pays a dividend. NTRA does not pay a meaningful dividend and should not be held primarily for income.

08

Is QGEN or NTRA better for a retirement portfolio?

For long-horizon retirement investors, Qiagen N.

V. (QGEN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 42), 0. 8% yield). Both have compounded well over 10 years (QGEN: +65. 1%, NTRA: +20. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between QGEN and NTRA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: QGEN is a small-cap deep-value stock; NTRA is a mid-cap high-growth stock. QGEN pays a dividend while NTRA does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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QGEN

Quality Mega-Cap Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 12%
  • Dividend Yield > 0.5%
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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 19%
  • Gross Margin > 38%
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