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SABS vs IMVT vs ARGX vs HALO vs ADMA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
SABS vs IMVT vs ARGX vs HALO vs ADMA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $195M | $5.53B | $48.72B | $7.68B | $2.03B |
| Revenue (TTM) | $0.00 | $0.00 | $5.60B | $1.40B | $510M |
| Net Income (TTM) | $13M | $-464M | $1.95B | $317M | $165M |
| Gross Margin | — | — | 88.3% | 81.9% | 61.3% |
| Operating Margin | — | — | 15.0% | 58.4% | 42.1% |
| Forward P/E | — | — | 30.0x | 8.1x | 8.9x |
| Total Debt | $6M | $98K | $83M | $0.00 | $80M |
| Cash & Equiv. | $11M | $714M | $3.49B | $134M | $88M |
SABS vs IMVT vs ARGX vs HALO vs ADMA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 21 | May 26 | Return |
|---|---|---|---|
| SAB Biotherapeutics… (SABS) | 100 | 4.1 | -95.9% |
| Immunovant, Inc. (IMVT) | 100 | 172.5 | +72.5% |
| argenx SE (ARGX) | 100 | 238.1 | +138.1% |
| Halozyme Therapeuti… (HALO) | 100 | 144.1 | +44.1% |
| ADMA Biologics, Inc. (ADMA) | 100 | 366.7 | +266.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: SABS vs IMVT vs ARGX vs HALO vs ADMA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
SABS is the #2 pick in this set and the best alternative if momentum is your priority.
- +142.0% vs ADMA's -64.1%
IMVT lags the leaders in this set but could rank higher in a more targeted comparison.
ARGX carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 0.52
- Rev growth 90.1%, EPS growth 53.6%, 3Y rev CAGR 116.4%
- 33.2% 10Y total return vs HALO's 5.7%
- Lower volatility, beta 0.52, Low D/E 1.1%, current ratio 5.23x
HALO ranks third and is worth considering specifically for value.
- Lower P/E (8.1x vs 8.9x)
Among these 5 stocks, ADMA doesn't own a clear edge in any measured category.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 90.1% revenue growth vs SABS's -100.0% | |
| Value | Lower P/E (8.1x vs 8.9x) | |
| Quality / Margins | 34.9% margin vs IMVT's 3.2% | |
| Stability / Safety | Beta 0.52 vs IMVT's 1.37 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +142.0% vs ADMA's -64.1% | |
| Efficiency (ROA) | 29.1% ROA vs IMVT's -44.1% |
SABS vs IMVT vs ARGX vs HALO vs ADMA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
SABS vs IMVT vs ARGX vs HALO vs ADMA — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 2 of 6 categories
ARGX leads 1 • ADMA leads 1 • SABS leads 0 • IMVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ARGX leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ARGX and IMVT operate at a comparable scale, with $5.6B and $0 in trailing revenue. ARGX is the more profitable business, keeping 34.9% of every revenue dollar as net income compared to HALO's 22.7%. On growth, ARGX holds the edge at +78.7% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $5.6B | $1.4B | $510M |
| EBITDAEarnings before interest/tax | -$47M | -$487M | $999M | $945M | $221M |
| Net IncomeAfter-tax profit | $13M | -$464M | $2.0B | $317M | $165M |
| Free Cash FlowCash after capex | -$45M | -$423M | $755M | $645M | $108M |
| Gross MarginGross profit ÷ Revenue | — | — | +88.3% | +81.9% | +61.3% |
| Operating MarginEBIT ÷ Revenue | — | — | +15.0% | +58.4% | +42.1% |
| Net MarginNet income ÷ Revenue | — | — | +34.9% | +22.7% | +32.4% |
| FCF MarginFCF ÷ Revenue | — | — | +13.5% | +46.2% | +21.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | — | +78.7% | +51.6% | -0.3% |
| EPS Growth (YoY)Latest quarter vs prior year | +187.0% | +19.7% | +8.4% | -2.1% | +72.7% |
Valuation Metrics
HALO leads this category, winning 3 of 6 comparable metrics.
Valuation Metrics
At 14.1x trailing earnings, ADMA trades at a 65% valuation discount to ARGX's 40.1x P/E. On an enterprise value basis, HALO's 8.3x EV/EBITDA is more attractive than ARGX's 46.6x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $195M | $5.5B | $48.7B | $7.7B | $2.0B |
| Enterprise ValueMkt cap + debt − cash | $190M | $4.8B | $45.3B | $7.5B | $2.0B |
| Trailing P/EPrice ÷ TTM EPS | -5.18x | -9.97x | 40.11x | 25.46x | 14.12x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 29.95x | 8.09x | 8.88x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 1.11x | — |
| EV / EBITDAEnterprise value multiple | — | — | 46.60x | 8.34x | 10.15x |
| Price / SalesMarket cap ÷ Revenue | — | — | 11.70x | 5.50x | 3.98x |
| Price / BookPrice ÷ Book value/share | 1.66x | 5.83x | 7.10x | 165.47x | 4.35x |
| Price / FCFMarket cap ÷ FCF | — | — | 57.71x | 11.91x | 73.05x |
Profitability & Efficiency
HALO leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-47 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ADMA's 0.17x. On the Piotroski fundamental quality scale (0–9), HALO scores 5/9 vs IMVT's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +15.2% | -47.1% | +33.7% | +6.5% | +39.0% |
| ROA (TTM)Return on assets | +12.5% | -44.1% | +29.1% | +12.5% | +27.4% |
| ROICReturn on invested capital | -43.5% | — | +18.3% | +73.4% | +36.0% |
| ROCEReturn on capital employed | -49.4% | -66.1% | +15.1% | +38.2% | +38.8% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 2 | 4 | 5 | 5 |
| Debt / EquityFinancial leverage | 0.04x | 0.00x | 0.01x | — | 0.17x |
| Net DebtTotal debt minus cash | -$5M | -$714M | -$3.4B | -$134M | -$8M |
| Cash & Equiv.Liquid assets | $11M | $714M | $3.5B | $134M | $88M |
| Total DebtShort + long-term debt | $6M | $98,000 | $83M | $0 | $80M |
| Interest CoverageEBIT ÷ Interest expense | 266.50x | — | 326.52x | 46.08x | 50.85x |
Total Returns (Dividends Reinvested)
ADMA leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ADMA five years ago would be worth $48,678 today (with dividends reinvested), compared to $413 for SABS. Over the past 12 months, SABS leads with a +142.0% total return vs ADMA's -64.1%. The 3-year compound annual growth rate (CAGR) favors ADMA at 34.3% vs SABS's -25.3% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +8.5% | +5.1% | -6.3% | -7.3% | -52.6% |
| 1-Year ReturnPast 12 months | +142.0% | +96.1% | +26.4% | -7.1% | -64.1% |
| 3-Year ReturnCumulative with dividends | -58.3% | +40.9% | +93.9% | +115.3% | +142.0% |
| 5-Year ReturnCumulative with dividends | -95.9% | +62.4% | +198.6% | +37.0% | +386.8% |
| 10-Year ReturnCumulative with dividends | -96.0% | +173.6% | +3323.1% | +570.7% | +39.8% |
| CAGR (3Y)Annualised 3-year return | -25.3% | +12.1% | +24.7% | +29.1% | +34.3% |
Risk & Volatility
Evenly matched — IMVT and ARGX each lead in 1 of 2 comparable metrics.
Risk & Volatility
ARGX is the less volatile stock with a 0.52 beta — it tends to amplify market swings less than IMVT's 1.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs ADMA's 35.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.80x | 1.37x | 0.52x | 0.56x | 1.22x |
| 52-Week HighHighest price in past year | $6.60 | $30.09 | $934.62 | $82.22 | $23.98 |
| 52-Week LowLowest price in past year | $1.60 | $13.36 | $510.06 | $47.50 | $7.21 |
| % of 52W HighCurrent price vs 52-week peak | +62.0% | +90.5% | +84.2% | +79.3% | +35.3% |
| RSI (14)Momentum oscillator 0–100 | 51.5 | 60.2 | 57.3 | 52.4 | 37.9 |
| Avg Volume (50D)Average daily shares traded | 658K | 1.4M | 330K | 1.4M | 7.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: SABS as "Buy", IMVT as "Buy", ARGX as "Buy", HALO as "Buy", ADMA as "Buy". Consensus price targets imply 165.6% upside for ADMA (target: $23) vs 20.2% for HALO (target: $78).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $7.00 | $45.50 | $1052.30 | $78.33 | $22.50 |
| # AnalystsCovering analysts | 6 | 23 | 36 | 27 | 9 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +4.5% | +1.6% |
HALO leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). ARGX leads in 1 (Income & Cash Flow). 1 tied.
SABS vs IMVT vs ARGX vs HALO vs ADMA: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is SABS or IMVT or ARGX or HALO or ADMA a better buy right now?
For growth investors, argenx SE (ARGX) is the stronger pick with 90.
1% revenue growth year-over-year, versus -100. 0% for SAB Biotherapeutics, Inc. (SABS). ADMA Biologics, Inc. (ADMA) offers the better valuation at 14. 1x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate SAB Biotherapeutics, Inc. (SABS) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — SABS or IMVT or ARGX or HALO or ADMA?
On trailing P/E, ADMA Biologics, Inc.
(ADMA) is the cheapest at 14. 1x versus argenx SE at 40. 1x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 1x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — SABS or IMVT or ARGX or HALO or ADMA?
Over the past 5 years, ADMA Biologics, Inc.
(ADMA) delivered a total return of +386. 8%, compared to -95. 9% for SAB Biotherapeutics, Inc. (SABS). Over 10 years, the gap is even starker: ARGX returned +33. 2% versus SABS's -96. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — SABS or IMVT or ARGX or HALO or ADMA?
By beta (market sensitivity over 5 years), argenx SE (ARGX) is the lower-risk stock at 0.
52β versus Immunovant, Inc. 's 1. 37β — meaning IMVT is approximately 162% more volatile than ARGX relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 17% for ADMA Biologics, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — SABS or IMVT or ARGX or HALO or ADMA?
By revenue growth (latest reported year), argenx SE (ARGX) is pulling ahead at 90.
1% versus -100. 0% for SAB Biotherapeutics, Inc. (SABS). On earnings-per-share growth, the picture is similar: SAB Biotherapeutics, Inc. grew EPS 78. 5% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, ARGX leads at 116. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — SABS or IMVT or ARGX or HALO or ADMA?
argenx SE (ARGX) is the more profitable company, earning 31.
1% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 31. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus 0. 0% for IMVT. At the gross margin level — before operating expenses — ARGX leads at 89. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is SABS or IMVT or ARGX or HALO or ADMA more undervalued right now?
On forward earnings alone, Halozyme Therapeutics, Inc.
(HALO) trades at 8. 1x forward P/E versus 30. 0x for argenx SE — 21. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADMA: 165. 6% to $22. 50.
08Which pays a better dividend — SABS or IMVT or ARGX or HALO or ADMA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is SABS or IMVT or ARGX or HALO or ADMA better for a retirement portfolio?
For long-horizon retirement investors, Halozyme Therapeutics, Inc.
(HALO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 56), +570. 7% 10Y return). Both have compounded well over 10 years (HALO: +570. 7%, IMVT: +173. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between SABS and IMVT and ARGX and HALO and ADMA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: SABS is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; ARGX is a mid-cap high-growth stock; HALO is a small-cap high-growth stock; ADMA is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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