Medical - Healthcare Information Services
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SDGR vs CERT vs RXRX vs VEEV vs PFE
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Healthcare Information Services
Biotechnology
Medical - Healthcare Information Services
Drug Manufacturers - General
SDGR vs CERT vs RXRX vs VEEV vs PFE — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Healthcare Information Services | Medical - Healthcare Information Services | Biotechnology | Medical - Healthcare Information Services | Drug Manufacturers - General |
| Market Cap | $992M | $1.03B | $1.46B | $27.35B | $150.63B |
| Revenue (TTM) | $255M | $419M | $66M | $3.20B | $63.31B |
| Net Income (TTM) | $-103M | $-2M | $-560M | $909M | $7.49B |
| Gross Margin | 55.3% | 61.5% | -34.4% | 75.5% | 69.3% |
| Operating Margin | -64.7% | 5.0% | -8.8% | 28.7% | 23.4% |
| Forward P/E | — | 14.1x | — | 19.0x | 8.9x |
| Total Debt | $109M | $11M | $78M | $96M | $67.42B |
| Cash & Equiv. | $231M | $189M | $743M | $1.42B | $1.14B |
SDGR vs CERT vs RXRX vs VEEV vs PFE — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Apr 21 | May 26 | Return |
|---|---|---|---|
| Schrödinger, Inc. (SDGR) | 100 | 17.4 | -82.6% |
| Certara, Inc. (CERT) | 100 | 19.8 | -80.2% |
| Recursion Pharmaceu… (RXRX) | 100 | 9.8 | -90.2% |
| Veeva Systems Inc. (VEEV) | 100 | 59.6 | -40.4% |
| Pfizer Inc. (PFE) | 100 | 68.5 | -31.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: SDGR vs CERT vs RXRX vs VEEV vs PFE
Each card shows where this stock fits in a portfolio — not just who wins on paper.
SDGR lags the leaders in this set but could rank higher in a more targeted comparison.
Among these 5 stocks, CERT doesn't own a clear edge in any measured category.
RXRX ranks third and is worth considering specifically for growth exposure.
- Rev growth 26.9%, EPS growth 14.8%, 3Y rev CAGR 23.5%
- 26.9% revenue growth vs PFE's -1.6%
VEEV is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.
- 5.2% 10Y total return vs PFE's 29.6%
- Lower volatility, beta 0.77, Low D/E 1.3%, current ratio 4.89x
- Beta 0.77, current ratio 4.89x
- 28.4% margin vs RXRX's -8.4%
PFE carries the broadest edge in this set and is the clearest fit for income & stability.
- Dividend streak 15 yrs, beta 0.54, yield 6.5%
- Lower P/E (8.9x vs 19.0x)
- Beta 0.54 vs RXRX's 3.18
- 6.5% yield; 15-year raise streak; the other 4 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 26.9% revenue growth vs PFE's -1.6% | |
| Value | Lower P/E (8.9x vs 19.0x) | |
| Quality / Margins | 28.4% margin vs RXRX's -8.4% | |
| Stability / Safety | Beta 0.54 vs RXRX's 3.18 | |
| Dividends | 6.5% yield; 15-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +23.7% vs CERT's -44.9% | |
| Efficiency (ROA) | 11.1% ROA vs RXRX's -40.6%, ROIC 12.9% vs -95.8% |
SDGR vs CERT vs RXRX vs VEEV vs PFE — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
SDGR vs CERT vs RXRX vs VEEV vs PFE — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
VEEV leads in 2 of 6 categories
PFE leads 1 • SDGR leads 0 • CERT leads 0 • RXRX leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
VEEV leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PFE is the larger business by revenue, generating $63.3B annually — 955.2x RXRX's $66M. VEEV is the more profitable business, keeping 28.4% of every revenue dollar as net income compared to RXRX's -8.4%. On growth, VEEV holds the edge at +16.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $255M | $419M | $66M | $3.2B | $63.3B |
| EBITDAEarnings before interest/tax | -$159M | $78M | -$521M | $956M | $21.0B |
| Net IncomeAfter-tax profit | -$103M | -$2M | -$560M | $909M | $7.5B |
| Free Cash FlowCash after capex | -$148M | $67M | -$326M | $1.4B | $9.5B |
| Gross MarginGross profit ÷ Revenue | +55.3% | +61.5% | -34.4% | +75.5% | +69.3% |
| Operating MarginEBIT ÷ Revenue | -64.7% | +5.0% | -8.8% | +28.7% | +23.4% |
| Net MarginNet income ÷ Revenue | -40.6% | -0.4% | -8.4% | +28.4% | +11.8% |
| FCF MarginFCF ÷ Revenue | -58.2% | +15.9% | -4.9% | +43.7% | +15.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | -1.6% | +3.3% | -56.1% | +16.0% | +5.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +1.2% | -191.0% | +56.0% | +23.9% | -9.5% |
Valuation Metrics
Evenly matched — CERT and PFE each lead in 3 of 6 comparable metrics.
Valuation Metrics
At 19.5x trailing earnings, PFE trades at a 37% valuation discount to VEEV's 30.9x P/E. On an enterprise value basis, PFE's 10.7x EV/EBITDA is more attractive than VEEV's 28.4x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $992M | $1.0B | $1.5B | $27.4B | $150.6B |
| Enterprise ValueMkt cap + debt − cash | $871M | $857M | $797M | $26.0B | $216.9B |
| Trailing P/EPrice ÷ TTM EPS | -9.42x | -631.00x | -2.27x | 30.92x | 19.47x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 14.10x | — | 18.98x | 8.94x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 1.70x | — |
| EV / EBITDAEnterprise value multiple | — | 11.05x | — | 28.40x | 10.66x |
| Price / SalesMarket cap ÷ Revenue | 3.88x | 2.47x | 19.58x | 8.56x | 2.41x |
| Price / BookPrice ÷ Book value/share | 2.68x | 0.95x | 1.29x | 3.89x | 1.74x |
| Price / FCFMarket cap ÷ FCF | 79.66x | 10.94x | — | 19.33x | 16.60x |
Profitability & Efficiency
VEEV leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
VEEV delivers a 13.4% return on equity — every $100 of shareholder capital generates $13 in annual profit, vs $-54 for RXRX. CERT carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to PFE's 0.78x. On the Piotroski fundamental quality scale (0–9), PFE scores 7/9 vs RXRX's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -30.8% | -0.2% | -54.3% | +13.4% | +8.3% |
| ROA (TTM)Return on assets | -15.3% | -0.1% | -40.6% | +11.1% | +3.6% |
| ROICReturn on invested capital | -39.4% | +1.5% | -95.8% | +12.9% | +7.5% |
| ROCEReturn on capital employed | -28.6% | +1.5% | -50.1% | +13.8% | +9.0% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 6 | 4 | 6 | 7 |
| Debt / EquityFinancial leverage | 0.30x | 0.01x | 0.07x | 0.01x | 0.78x |
| Net DebtTotal debt minus cash | -$121M | -$178M | -$665M | -$1.3B | $66.3B |
| Cash & Equiv.Liquid assets | $231M | $189M | $743M | $1.4B | $1.1B |
| Total DebtShort + long-term debt | $109M | $11M | $78M | $96M | $67.4B |
| Interest CoverageEBIT ÷ Interest expense | — | — | -336.46x | — | 4.02x |
Total Returns (Dividends Reinvested)
Evenly matched — VEEV and PFE each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in PFE five years ago would be worth $8,674 today (with dividends reinvested), compared to $1,179 for RXRX. Over the past 12 months, PFE leads with a +23.7% total return vs CERT's -44.9%. The 3-year compound annual growth rate (CAGR) favors VEEV at -1.8% vs CERT's -35.4% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -26.1% | -27.8% | -22.1% | -23.4% | +6.9% |
| 1-Year ReturnPast 12 months | -44.0% | -44.9% | -22.0% | -29.4% | +23.7% |
| 3-Year ReturnCumulative with dividends | -52.1% | -73.1% | -41.6% | -5.2% | -18.4% |
| 5-Year ReturnCumulative with dividends | -80.6% | -78.6% | -88.2% | -35.3% | -13.3% |
| 10-Year ReturnCumulative with dividends | -53.6% | -83.4% | -81.8% | +519.4% | +29.6% |
| CAGR (3Y)Annualised 3-year return | -21.8% | -35.4% | -16.4% | -1.8% | -6.6% |
Risk & Volatility
PFE leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
PFE is the less volatile stock with a 0.54 beta — it tends to amplify market swings less than RXRX's 3.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PFE currently trades 92.1% from its 52-week high vs CERT's 45.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.72x | 1.21x | 3.18x | 0.77x | 0.54x |
| 52-Week HighHighest price in past year | $27.63 | $13.88 | $7.18 | $310.50 | $28.75 |
| 52-Week LowLowest price in past year | $10.95 | $5.19 | $2.80 | $148.05 | $21.97 |
| % of 52W HighCurrent price vs 52-week peak | +48.1% | +45.5% | +45.5% | +54.2% | +92.1% |
| RSI (14)Momentum oscillator 0–100 | 59.8 | 53.5 | 49.5 | 49.6 | 44.2 |
| Avg Volume (50D)Average daily shares traded | 1.3M | 3.5M | 12.5M | 2.3M | 33.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: SDGR as "Buy", CERT as "Buy", RXRX as "Hold", VEEV as "Buy", PFE as "Hold". Consensus price targets imply 236.4% upside for RXRX (target: $11) vs 3.0% for PFE (target: $27). PFE is the only dividend payer here at 6.49% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy | Hold |
| Price TargetConsensus 12-month target | $18.00 | $10.00 | $11.00 | $280.10 | $27.27 |
| # AnalystsCovering analysts | 12 | 14 | 10 | 42 | 39 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +6.5% |
| Dividend StreakConsecutive years of raises | — | — | — | — | 15 |
| Dividend / ShareAnnual DPS | — | — | — | — | $1.72 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +4.1% | 0.0% | +0.6% | 0.0% |
VEEV leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PFE leads in 1 (Risk & Volatility). 2 tied.
SDGR vs CERT vs RXRX vs VEEV vs PFE: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is SDGR or CERT or RXRX or VEEV or PFE a better buy right now?
For growth investors, Recursion Pharmaceuticals, Inc.
(RXRX) is the stronger pick with 26. 9% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). Pfizer Inc. (PFE) offers the better valuation at 19. 5x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate Schrödinger, Inc. (SDGR) a "Buy" — based on 12 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — SDGR or CERT or RXRX or VEEV or PFE?
On trailing P/E, Pfizer Inc.
(PFE) is the cheapest at 19. 5x versus Veeva Systems Inc. at 30. 9x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 9x.
03Which is the better long-term investment — SDGR or CERT or RXRX or VEEV or PFE?
Over the past 5 years, Pfizer Inc.
(PFE) delivered a total return of -13. 3%, compared to -88. 2% for Recursion Pharmaceuticals, Inc. (RXRX). Over 10 years, the gap is even starker: VEEV returned +519. 4% versus CERT's -83. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — SDGR or CERT or RXRX or VEEV or PFE?
By beta (market sensitivity over 5 years), Pfizer Inc.
(PFE) is the lower-risk stock at 0. 54β versus Recursion Pharmaceuticals, Inc. 's 3. 18β — meaning RXRX is approximately 484% more volatile than PFE relative to the S&P 500. On balance sheet safety, Certara, Inc. (CERT) carries a lower debt/equity ratio of 1% versus 78% for Pfizer Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — SDGR or CERT or RXRX or VEEV or PFE?
By revenue growth (latest reported year), Recursion Pharmaceuticals, Inc.
(RXRX) is pulling ahead at 26. 9% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: Certara, Inc. grew EPS 86. 7% year-over-year, compared to -3. 5% for Pfizer Inc.. Over a 3-year CAGR, RXRX leads at 23. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — SDGR or CERT or RXRX or VEEV or PFE?
Veeva Systems Inc.
(VEEV) is the more profitable company, earning 28. 4% net margin versus -863. 4% for Recursion Pharmaceuticals, Inc. — meaning it keeps 28. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: VEEV leads at 28. 7% versus -867. 9% for RXRX. At the gross margin level — before operating expenses — VEEV leads at 75. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is SDGR or CERT or RXRX or VEEV or PFE more undervalued right now?
On forward earnings alone, Pfizer Inc.
(PFE) trades at 8. 9x forward P/E versus 19. 0x for Veeva Systems Inc. — 10. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for RXRX: 236. 4% to $11. 00.
08Which pays a better dividend — SDGR or CERT or RXRX or VEEV or PFE?
In this comparison, PFE (6.
5% yield) pays a dividend. SDGR, CERT, RXRX, VEEV do not pay a meaningful dividend and should not be held primarily for income.
09Is SDGR or CERT or RXRX or VEEV or PFE better for a retirement portfolio?
For long-horizon retirement investors, Pfizer Inc.
(PFE) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 54), 6. 5% yield). Recursion Pharmaceuticals, Inc. (RXRX) carries a higher beta of 3. 18 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PFE: +29. 6%, RXRX: -81. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between SDGR and CERT and RXRX and VEEV and PFE?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: SDGR is a small-cap high-growth stock; CERT is a small-cap quality compounder stock; RXRX is a small-cap high-growth stock; VEEV is a mid-cap high-growth stock; PFE is a mid-cap income-oriented stock. PFE pays a dividend while SDGR, CERT, RXRX, VEEV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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