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SDGR vs NVDA vs AMD vs RXRX vs INTC

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
SDGR
Schrödinger, Inc.

Medical - Healthcare Information Services

HealthcareNASDAQ • US
Market Cap$992M
5Y Perf.-82.6%
NVDA
NVIDIA Corporation

Semiconductors

TechnologyNASDAQ • US
Market Cap$5.14T
5Y Perf.+1309.0%
AMD
Advanced Micro Devices, Inc.

Semiconductors

TechnologyNASDAQ • US
Market Cap$665.93B
5Y Perf.+400.4%
RXRX
Recursion Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.46B
5Y Perf.-90.2%
INTC
Intel Corporation

Semiconductors

TechnologyNASDAQ • US
Market Cap$550.40B
5Y Perf.+90.5%

SDGR vs NVDA vs AMD vs RXRX vs INTC — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
SDGR logoSDGR
NVDA logoNVDA
AMD logoAMD
RXRX logoRXRX
INTC logoINTC
IndustryMedical - Healthcare Information ServicesSemiconductorsSemiconductorsBiotechnologySemiconductors
Market Cap$992M$5.14T$665.93B$1.46B$550.40B
Revenue (TTM)$255M$215.94B$37.45B$66M$53.76B
Net Income (TTM)$-103M$120.07B$4.99B$-560M$-3.17B
Gross Margin55.3%71.1%50.3%-34.4%35.4%
Operating Margin-64.7%60.4%11.7%-8.8%-9.4%
Forward P/E25.6x59.7x105.1x
Total Debt$109M$11.41B$4.47B$78M$46.59B
Cash & Equiv.$231M$10.61B$5.54B$743M$14.27B

SDGR vs NVDA vs AMD vs RXRX vs INTCLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

SDGR
NVDA
AMD
RXRX
INTC
StockApr 21May 26Return
Schrödinger, Inc. (SDGR)10017.4-82.6%
NVIDIA Corporation (NVDA)1001409.0+1309.0%
Advanced Micro Devi… (AMD)100500.4+400.4%
Recursion Pharmaceu… (RXRX)1009.8-90.2%
Intel Corporation (INTC)100190.5+90.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: SDGR vs NVDA vs AMD vs RXRX vs INTC

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: NVDA leads in 5 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Schrödinger, Inc. is the stronger pick specifically for capital preservation and lower volatility. INTC also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
SDGR
Schrödinger, Inc.
The Defensive Choice

SDGR is the #2 pick in this set and the best alternative if stability is your priority.

  • Beta 1.72 vs RXRX's 3.18
Best for: stability
NVDA
NVIDIA Corporation
The Income Pick

NVDA carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 2 yrs, beta 1.73, yield 0.0%
  • Rev growth 65.5%, EPS growth 66.7%, 3Y rev CAGR 100.0%
  • 239.0% 10Y total return vs AMD's 110.9%
  • Lower volatility, beta 1.73, Low D/E 7.3%, current ratio 3.91x
Best for: income & stability and growth exposure
AMD
Advanced Micro Devices, Inc.
The Growth Angle

AMD lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: technology exposure
RXRX
Recursion Pharmaceuticals, Inc.
The Growth Angle

Among these 5 stocks, RXRX doesn't own a clear edge in any measured category.

Best for: healthcare exposure
INTC
Intel Corporation
The Momentum Pick

INTC ranks third and is worth considering specifically for momentum.

  • +439.7% vs SDGR's -44.0%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthNVDA logoNVDA65.5% revenue growth vs INTC's -0.5%
ValueNVDA logoNVDALower P/E (25.6x vs 105.1x)
Quality / MarginsNVDA logoNVDA55.6% margin vs RXRX's -8.4%
Stability / SafetySDGR logoSDGRBeta 1.72 vs RXRX's 3.18
DividendsNVDA logoNVDA0.0% yield; 2-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)INTC logoINTC+439.7% vs SDGR's -44.0%
Efficiency (ROA)NVDA logoNVDA58.1% ROA vs RXRX's -40.6%, ROIC 81.8% vs -95.8%

SDGR vs NVDA vs AMD vs RXRX vs INTC — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

SDGRSchrödinger, Inc.
FY 2025
Software Products And Services
34.2%$200M
Revenue From Contract With Customer Before Software Contribution
31.5%$184M
On Premise Software
17.4%$101M
Hosted Software
7.7%$45M
Maintenance
4.7%$27M
Software Contribution
2.7%$16M
Professional Services
1.7%$10M
NVDANVIDIA Corporation
FY 2026
Data Center
89.7%$193.7B
Gaming
7.4%$16.0B
Professional Visualization
1.5%$3.2B
Automotive
1.1%$2.3B
OEM And Other
0.3%$619M
AMDAdvanced Micro Devices, Inc.
FY 2025
Data Center
43.2%$16.6B
Client and Gaming
37.7%$14.6B
Gaming
10.1%$3.9B
Embedded
9.0%$3.5B
RXRXRecursion Pharmaceuticals, Inc.
FY 2025
License and Service
99.4%$74M
Grant
0.6%$425,000
INTCIntel Corporation
FY 2025
Client Computing Group
61.0%$32.2B
Intel Foundry Services
33.7%$17.8B
Data Center Group
32.0%$16.9B
Other Segments
6.7%$3.6B
Intersegment Eliminations
-33.5%$-17,683,000,000

SDGR vs NVDA vs AMD vs RXRX vs INTC — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLNVDALAGGINGINTC

Income & Cash Flow (Last 12 Months)

NVDA leads this category, winning 6 of 6 comparable metrics.

NVDA is the larger business by revenue, generating $215.9B annually — 3257.6x RXRX's $66M. NVDA is the more profitable business, keeping 55.6% of every revenue dollar as net income compared to RXRX's -8.4%. On growth, NVDA holds the edge at +73.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricSDGR logoSDGRSchrödinger, Inc.NVDA logoNVDANVIDIA CorporationAMD logoAMDAdvanced Micro De…RXRX logoRXRXRecursion Pharmac…INTC logoINTCIntel Corporation
RevenueTrailing 12 months$255M$215.9B$37.5B$66M$53.8B
EBITDAEarnings before interest/tax-$159M$133.2B$6.6B-$521M$4.0B
Net IncomeAfter-tax profit-$103M$120.1B$5.0B-$560M-$3.2B
Free Cash FlowCash after capex-$148M$96.7B$8.6B-$326M-$3.1B
Gross MarginGross profit ÷ Revenue+55.3%+71.1%+50.3%-34.4%+35.4%
Operating MarginEBIT ÷ Revenue-64.7%+60.4%+11.7%-8.8%-9.4%
Net MarginNet income ÷ Revenue-40.6%+55.6%+13.3%-8.4%-5.9%
FCF MarginFCF ÷ Revenue-58.2%+44.8%+22.9%-4.9%-5.8%
Rev. Growth (YoY)Latest quarter vs prior year-1.6%+73.2%+37.8%-56.1%+7.2%
EPS Growth (YoY)Latest quarter vs prior year+1.2%+97.8%+90.9%+56.0%-2.8%
NVDA leads this category, winning 6 of 6 comparable metrics.

Valuation Metrics

NVDA leads this category, winning 4 of 7 comparable metrics.

At 43.2x trailing earnings, NVDA trades at a 72% valuation discount to AMD's 154.1x P/E. Adjusting for growth (PEG ratio), NVDA offers better value at 0.45x vs AMD's 29.84x — a lower PEG means you pay less per unit of expected earnings growth.

MetricSDGR logoSDGRSchrödinger, Inc.NVDA logoNVDANVIDIA CorporationAMD logoAMDAdvanced Micro De…RXRX logoRXRXRecursion Pharmac…INTC logoINTCIntel Corporation
Market CapShares × price$992M$5.14T$665.9B$1.5B$550.4B
Enterprise ValueMkt cap + debt − cash$871M$5.14T$664.9B$797M$582.7B
Trailing P/EPrice ÷ TTM EPS-9.42x43.16x154.14x-2.27x-1861.12x
Forward P/EPrice ÷ next-FY EPS est.25.55x59.65x105.10x
PEG RatioP/E ÷ EPS growth rate0.45x29.84x
EV / EBITDAEnterprise value multiple38.59x99.26x49.88x
Price / SalesMarket cap ÷ Revenue3.88x23.80x19.22x19.58x10.41x
Price / BookPrice ÷ Book value/share2.68x32.85x10.61x1.29x4.21x
Price / FCFMarket cap ÷ FCF79.66x53.17x98.88x
NVDA leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

NVDA leads this category, winning 5 of 9 comparable metrics.

NVDA delivers a 76.3% return on equity — every $100 of shareholder capital generates $76 in annual profit, vs $-54 for RXRX. RXRX carries lower financial leverage with a 0.07x debt-to-equity ratio, signaling a more conservative balance sheet compared to INTC's 0.37x. On the Piotroski fundamental quality scale (0–9), AMD scores 8/9 vs RXRX's 4/9, reflecting strong financial health.

MetricSDGR logoSDGRSchrödinger, Inc.NVDA logoNVDANVIDIA CorporationAMD logoAMDAdvanced Micro De…RXRX logoRXRXRecursion Pharmac…INTC logoINTCIntel Corporation
ROE (TTM)Return on equity-30.8%+76.3%+8.1%-54.3%-2.7%
ROA (TTM)Return on assets-15.3%+58.1%+6.5%-40.6%-1.6%
ROICReturn on invested capital-39.4%+81.8%+4.7%-95.8%-0.0%
ROCEReturn on capital employed-28.6%+97.2%+5.7%-50.1%-0.0%
Piotroski ScoreFundamental quality 0–944846
Debt / EquityFinancial leverage0.30x0.07x0.07x0.07x0.37x
Net DebtTotal debt minus cash-$121M$807M-$1.1B-$665M$32.3B
Cash & Equiv.Liquid assets$231M$10.6B$5.5B$743M$14.3B
Total DebtShort + long-term debt$109M$11.4B$4.5B$78M$46.6B
Interest CoverageEBIT ÷ Interest expense545.03x33.19x-336.46x3.71x
NVDA leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NVDA leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in NVDA five years ago would be worth $142,893 today (with dividends reinvested), compared to $1,179 for RXRX. Over the past 12 months, INTC leads with a +439.7% total return vs SDGR's -44.0%. The 3-year compound annual growth rate (CAGR) favors NVDA at 93.6% vs SDGR's -21.8% — a key indicator of consistent wealth creation.

MetricSDGR logoSDGRSchrödinger, Inc.NVDA logoNVDANVIDIA CorporationAMD logoAMDAdvanced Micro De…RXRX logoRXRXRecursion Pharmac…INTC logoINTCIntel Corporation
YTD ReturnYear-to-date-26.1%+12.0%+82.8%-22.1%+178.4%
1-Year ReturnPast 12 months-44.0%+80.7%+307.0%-22.0%+439.7%
3-Year ReturnCumulative with dividends-52.1%+625.9%+329.8%-41.6%+258.3%
5-Year ReturnCumulative with dividends-80.6%+1328.9%+418.3%-88.2%+95.8%
10-Year ReturnCumulative with dividends-53.6%+23902.3%+11090.7%-81.8%+299.2%
CAGR (3Y)Annualised 3-year return-21.8%+93.6%+62.6%-16.4%+53.0%
NVDA leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — SDGR and NVDA each lead in 1 of 2 comparable metrics.

SDGR is the less volatile stock with a 1.72 beta — it tends to amplify market swings less than RXRX's 3.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NVDA currently trades 97.6% from its 52-week high vs RXRX's 45.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSDGR logoSDGRSchrödinger, Inc.NVDA logoNVDANVIDIA CorporationAMD logoAMDAdvanced Micro De…RXRX logoRXRXRecursion Pharmac…INTC logoINTCIntel Corporation
Beta (5Y)Sensitivity to S&P 5001.72x1.73x2.30x3.18x2.15x
52-Week HighHighest price in past year$27.63$216.80$430.57$7.18$114.51
52-Week LowLowest price in past year$10.95$112.28$96.88$2.80$18.97
% of 52W HighCurrent price vs 52-week peak+48.1%+97.6%+94.9%+45.5%+95.7%
RSI (14)Momentum oscillator 0–10059.860.781.249.585.9
Avg Volume (50D)Average daily shares traded1.3M164.5M36.4M12.5M110.6M
Evenly matched — SDGR and NVDA each lead in 1 of 2 comparable metrics.

Analyst Outlook

NVDA leads this category, winning 1 of 1 comparable metric.

Analyst consensus: SDGR as "Buy", NVDA as "Buy", AMD as "Buy", RXRX as "Hold", INTC as "Hold". Consensus price targets imply 236.4% upside for RXRX (target: $11) vs -29.6% for INTC (target: $77).

MetricSDGR logoSDGRSchrödinger, Inc.NVDA logoNVDANVIDIA CorporationAMD logoAMDAdvanced Micro De…RXRX logoRXRXRecursion Pharmac…INTC logoINTCIntel Corporation
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHoldHold
Price TargetConsensus 12-month target$18.00$278.83$310.86$11.00$77.18
# AnalystsCovering analysts1279701084
Dividend YieldAnnual dividend ÷ price+0.0%
Dividend StreakConsecutive years of raises200
Dividend / ShareAnnual DPS$0.04
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.8%+0.2%0.0%0.0%
NVDA leads this category, winning 1 of 1 comparable metric.
Key Takeaway

NVDA leads in 5 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 1 category is tied.

Best OverallNVIDIA Corporation (NVDA)Leads 5 of 6 categories
Loading custom metrics...

SDGR vs NVDA vs AMD vs RXRX vs INTC: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is SDGR or NVDA or AMD or RXRX or INTC a better buy right now?

For growth investors, NVIDIA Corporation (NVDA) is the stronger pick with 65.

5% revenue growth year-over-year, versus -0. 5% for Intel Corporation (INTC). NVIDIA Corporation (NVDA) offers the better valuation at 43. 2x trailing P/E (25. 6x forward), making it the more compelling value choice. Analysts rate Schrödinger, Inc. (SDGR) a "Buy" — based on 12 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — SDGR or NVDA or AMD or RXRX or INTC?

On trailing P/E, NVIDIA Corporation (NVDA) is the cheapest at 43.

2x versus Advanced Micro Devices, Inc. at 154. 1x. On forward P/E, NVIDIA Corporation is actually cheaper at 25. 6x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: NVIDIA Corporation wins at 0. 27x versus Advanced Micro Devices, Inc. 's 11. 55x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — SDGR or NVDA or AMD or RXRX or INTC?

Over the past 5 years, NVIDIA Corporation (NVDA) delivered a total return of +1329%, compared to -88.

2% for Recursion Pharmaceuticals, Inc. (RXRX). Over 10 years, the gap is even starker: NVDA returned +239. 0% versus RXRX's -81. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — SDGR or NVDA or AMD or RXRX or INTC?

By beta (market sensitivity over 5 years), Schrödinger, Inc.

(SDGR) is the lower-risk stock at 1. 72β versus Recursion Pharmaceuticals, Inc. 's 3. 18β — meaning RXRX is approximately 84% more volatile than SDGR relative to the S&P 500. On balance sheet safety, Recursion Pharmaceuticals, Inc. (RXRX) carries a lower debt/equity ratio of 7% versus 37% for Intel Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — SDGR or NVDA or AMD or RXRX or INTC?

By revenue growth (latest reported year), NVIDIA Corporation (NVDA) is pulling ahead at 65.

5% versus -0. 5% for Intel Corporation (INTC). On earnings-per-share growth, the picture is similar: Advanced Micro Devices, Inc. grew EPS 165. 0% year-over-year, compared to 14. 8% for Recursion Pharmaceuticals, Inc.. Over a 3-year CAGR, NVDA leads at 100. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — SDGR or NVDA or AMD or RXRX or INTC?

NVIDIA Corporation (NVDA) is the more profitable company, earning 55.

6% net margin versus -863. 4% for Recursion Pharmaceuticals, Inc. — meaning it keeps 55. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVDA leads at 60. 4% versus -867. 9% for RXRX. At the gross margin level — before operating expenses — NVDA leads at 71. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is SDGR or NVDA or AMD or RXRX or INTC more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, NVIDIA Corporation (NVDA) is the more undervalued stock at a PEG of 0. 27x versus Advanced Micro Devices, Inc. 's 11. 55x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, NVIDIA Corporation (NVDA) trades at 25. 6x forward P/E versus 105. 1x for Intel Corporation — 79. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for RXRX: 236. 4% to $11. 00.

08

Which pays a better dividend — SDGR or NVDA or AMD or RXRX or INTC?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is SDGR or NVDA or AMD or RXRX or INTC better for a retirement portfolio?

For long-horizon retirement investors, NVIDIA Corporation (NVDA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+239.

0% 10Y return). Recursion Pharmaceuticals, Inc. (RXRX) carries a higher beta of 3. 18 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (NVDA: +239. 0%, RXRX: -81. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between SDGR and NVDA and AMD and RXRX and INTC?

These companies operate in different sectors (SDGR (Healthcare) and NVDA (Technology) and AMD (Technology) and RXRX (Healthcare) and INTC (Technology)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: SDGR is a small-cap high-growth stock; NVDA is a mega-cap high-growth stock; AMD is a large-cap high-growth stock; RXRX is a small-cap high-growth stock; INTC is a large-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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