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Stock Comparison

SMTI vs NVCR vs INVA vs HOLX vs BDX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
SMTI
Sanara MedTech Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$164M
5Y Perf.+55.3%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$2.04B
5Y Perf.-73.5%
INVA
Innoviva, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.69B
5Y Perf.+63.9%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+42.6%
BDX
Becton, Dickinson and Company

Medical - Instruments & Supplies

HealthcareNYSE • US
Market Cap$54.14B
5Y Perf.+0.4%

SMTI vs NVCR vs INVA vs HOLX vs BDX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
SMTI logoSMTI
NVCR logoNVCR
INVA logoINVA
HOLX logoHOLX
BDX logoBDX
IndustryMedical - Instruments & SuppliesMedical - Instruments & SuppliesBiotechnologyMedical - Instruments & SuppliesMedical - Instruments & Supplies
Market Cap$164M$2.04B$1.69B$16.97B$54.14B
Revenue (TTM)$103M$674M$424M$4.13B$21.36B
Net Income (TTM)$-38M$-173M$504M$544M$1.14B
Gross Margin92.7%75.2%76.2%52.8%46.5%
Operating Margin4.9%-27.2%14.8%17.5%10.6%
Forward P/E160.0x7.3x17.2x11.9x
Total Debt$48M$290M$269M$2.63B$19.18B
Cash & Equiv.$17M$103M$551M$1.96B$851M

SMTI vs NVCR vs INVA vs HOLX vs BDXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

SMTI
NVCR
INVA
HOLX
BDX
StockMay 20May 26Return
Sanara MedTech Inc. (SMTI)100155.3+55.3%
NovoCure Limited (NVCR)10026.5-73.5%
Innoviva, Inc. (INVA)100163.9+63.9%
Hologic, Inc. (HOLX)100142.6+42.6%
Becton, Dickinson a… (BDX)100100.4+0.4%

Price return only. Dividends and distributions are not included.

Quick Verdict: SMTI vs NVCR vs INVA vs HOLX vs BDX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INVA leads in 4 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Becton, Dickinson and Company is the stronger pick specifically for dividend income and shareholder returns and recent price momentum and sentiment. SMTI also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
SMTI
Sanara MedTech Inc.
The Income Pick

SMTI ranks third and is worth considering specifically for income & stability.

  • Dividend streak 1 yrs, beta 1.37
  • 19.0% revenue growth vs HOLX's 1.7%
Best for: income & stability
NVCR
NovoCure Limited
The Healthcare Pick

NVCR lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
INVA
Innoviva, Inc.
The Growth Play

INVA carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.

  • Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
  • Lower volatility, beta 0.11, Low D/E 22.9%, current ratio 14.64x
  • PEG 0.71 vs BDX's 0.72
  • Beta 0.11, current ratio 14.64x
Best for: growth exposure and sleep-well-at-night
HOLX
Hologic, Inc.
The Long-Run Compounder

HOLX is the clearest fit if your priority is long-term compounding.

  • 124.3% 10Y total return vs SMTI's 206.7%
Best for: long-term compounding
BDX
Becton, Dickinson and Company
The Income Pick

BDX is the #2 pick in this set and the best alternative if dividends and momentum is your priority.

  • 2.8% yield; 1-year raise streak; the other 4 pay no meaningful dividend
  • +47.3% vs SMTI's -43.2%
Best for: dividends and momentum
See the full category breakdown
CategoryWinnerWhy
GrowthSMTI logoSMTI19.0% revenue growth vs HOLX's 1.7%
ValueINVA logoINVALower P/E (7.3x vs 11.9x), PEG 0.71 vs 0.72
Quality / MarginsINVA logoINVA118.9% margin vs SMTI's -36.4%
Stability / SafetyINVA logoINVABeta 0.11 vs NVCR's 2.15, lower leverage
DividendsBDX logoBDX2.8% yield; 1-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)BDX logoBDX+47.3% vs SMTI's -43.2%
Efficiency (ROA)INVA logoINVA32.4% ROA vs SMTI's -49.2%, ROIC 14.2% vs 11.8%

SMTI vs NVCR vs INVA vs HOLX vs BDX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

SMTISanara MedTech Inc.
FY 2023
Royalty
100.0%$201,000
NVCRNovoCure Limited

Segment breakdown not available.

INVAInnoviva, Inc.
FY 2025
Royalty
57.5%$236M
Product
41.8%$172M
License And Other Revenue
0.7%$3M
HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
BDXBecton, Dickinson and Company
FY 2025
Medical
52.5%$11.5B
Interventional
23.9%$5.2B
Life Sciences
23.7%$5.2B

SMTI vs NVCR vs INVA vs HOLX vs BDX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLINVALAGGINGBDX

Income & Cash Flow (Last 12 Months)

INVA leads this category, winning 3 of 6 comparable metrics.

BDX is the larger business by revenue, generating $21.4B annually — 207.2x SMTI's $103M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to SMTI's -36.4%. On growth, NVCR holds the edge at +12.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricSMTI logoSMTISanara MedTech In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.HOLX logoHOLXHologic, Inc.BDX logoBDXBecton, Dickinson…
RevenueTrailing 12 months$103M$674M$424M$4.1B$21.4B
EBITDAEarnings before interest/tax$8M-$165M$86M$974M$4.2B
Net IncomeAfter-tax profit-$38M-$173M$504M$544M$1.1B
Free Cash FlowCash after capex$2M-$48M$181M$1000M$3.1B
Gross MarginGross profit ÷ Revenue+92.7%+75.2%+76.2%+52.8%+46.5%
Operating MarginEBIT ÷ Revenue+4.9%-27.2%+14.8%+17.5%+10.6%
Net MarginNet income ÷ Revenue-36.4%-25.7%+118.9%+13.2%+5.3%
FCF MarginFCF ÷ Revenue+2.1%-7.1%+42.6%+24.2%+14.7%
Rev. Growth (YoY)Latest quarter vs prior year+4.6%+12.3%+10.6%+2.5%-10.6%
EPS Growth (YoY)Latest quarter vs prior year+3.8%-100.0%+4.0%-9.2%-2.0%
INVA leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

INVA leads this category, winning 5 of 7 comparable metrics.

At 6.9x trailing earnings, INVA trades at a 77% valuation discount to HOLX's 30.5x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs BDX's 1.55x — a lower PEG means you pay less per unit of expected earnings growth.

MetricSMTI logoSMTISanara MedTech In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.HOLX logoHOLXHologic, Inc.BDX logoBDXBecton, Dickinson…
Market CapShares × price$164M$2.0B$1.7B$17.0B$54.1B
Enterprise ValueMkt cap + debt − cash$196M$2.2B$1.4B$17.6B$72.5B
Trailing P/EPrice ÷ TTM EPS-4.22x-14.66x6.94x30.53x25.63x
Forward P/EPrice ÷ next-FY EPS est.160.00x7.31x17.21x11.90x
PEG RatioP/E ÷ EPS growth rate0.67x1.55x
EV / EBITDAEnterprise value multiple19.66x6.90x17.39x14.38x
Price / SalesMarket cap ÷ Revenue1.59x3.11x3.97x4.14x2.48x
Price / BookPrice ÷ Book value/share26.76x5.86x1.65x3.43x1.69x
Price / FCFMarket cap ÷ FCF76.04x8.63x18.44x20.28x
INVA leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

INVA leads this category, winning 6 of 9 comparable metrics.

INVA delivers a 47.6% return on equity — every $100 of shareholder capital generates $48 in annual profit, vs $-179 for SMTI. INVA carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to SMTI's 8.13x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs SMTI's 4/9, reflecting strong financial health.

MetricSMTI logoSMTISanara MedTech In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.HOLX logoHOLXHologic, Inc.BDX logoBDXBecton, Dickinson…
ROE (TTM)Return on equity-178.6%-50.8%+47.6%+11.0%+4.5%
ROA (TTM)Return on assets-49.2%-16.5%+32.4%+6.1%+2.1%
ROICReturn on invested capital+11.8%-16.4%+14.2%+9.4%+4.3%
ROCEReturn on capital employed+15.6%-28.9%+12.4%+8.8%+5.4%
Piotroski ScoreFundamental quality 0–945577
Debt / EquityFinancial leverage8.13x0.85x0.23x0.52x0.76x
Net DebtTotal debt minus cash$32M$187M-$282M$667M$18.3B
Cash & Equiv.Liquid assets$17M$103M$551M$2.0B$851M
Total DebtShort + long-term debt$48M$290M$269M$2.6B$19.2B
Interest CoverageEBIT ÷ Interest expense-9.97x-96.80x63.45x8.00x4.09x
INVA leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

INVA leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in INVA five years ago would be worth $19,448 today (with dividends reinvested), compared to $983 for NVCR. Over the past 12 months, BDX leads with a +47.3% total return vs SMTI's -43.2%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.1% vs NVCR's -36.4% — a key indicator of consistent wealth creation.

MetricSMTI logoSMTISanara MedTech In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.HOLX logoHOLXHologic, Inc.BDX logoBDXBecton, Dickinson…
YTD ReturnYear-to-date-20.3%+36.4%+15.2%+1.9%-1.8%
1-Year ReturnPast 12 months-43.2%+2.6%+23.2%+35.3%+47.3%
3-Year ReturnCumulative with dividends-51.9%-74.2%+96.0%-8.5%+2.6%
5-Year ReturnCumulative with dividends-28.8%-90.2%+94.5%+16.8%+10.9%
10-Year ReturnCumulative with dividends+206.7%+38.5%+95.6%+124.3%+76.4%
CAGR (3Y)Annualised 3-year return-21.6%-36.4%+25.1%-2.9%+0.8%
INVA leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — INVA and HOLX each lead in 1 of 2 comparable metrics.

INVA is the less volatile stock with a 0.11 beta — it tends to amplify market swings less than NVCR's 2.15 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs SMTI's 51.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSMTI logoSMTISanara MedTech In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.HOLX logoHOLXHologic, Inc.BDX logoBDXBecton, Dickinson…
Beta (5Y)Sensitivity to S&P 5001.37x2.15x0.11x0.45x0.62x
52-Week HighHighest price in past year$35.95$20.06$25.15$76.04$205.52
52-Week LowLowest price in past year$16.04$9.82$16.52$53.62$100.31
% of 52W HighCurrent price vs 52-week peak+51.2%+89.2%+91.0%+100.0%+72.7%
RSI (14)Momentum oscillator 0–10050.870.944.769.150.9
Avg Volume (50D)Average daily shares traded56K1.4M604K10.3M2.5M
Evenly matched — INVA and HOLX each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — SMTI and BDX each lead in 1 of 1 comparable metric.

Analyst consensus: SMTI as "Buy", NVCR as "Buy", INVA as "Buy", HOLX as "Hold", BDX as "Hold". Consensus price targets imply 87.3% upside for NVCR (target: $34) vs 3.9% for HOLX (target: $79). BDX is the only dividend payer here at 2.79% yield — a key consideration for income-focused portfolios.

MetricSMTI logoSMTISanara MedTech In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.HOLX logoHOLXHologic, Inc.BDX logoBDXBecton, Dickinson…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHoldHold
Price TargetConsensus 12-month target$32.00$33.50$40.00$79.00$172.85
# AnalystsCovering analysts315104234
Dividend YieldAnnual dividend ÷ price+2.8%
Dividend StreakConsecutive years of raises101
Dividend / ShareAnnual DPS$4.17
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.3%+4.4%+1.8%
Evenly matched — SMTI and BDX each lead in 1 of 1 comparable metric.
Key Takeaway

INVA leads in 4 of 6 categories — strongest in Income & Cash Flow and Valuation Metrics. 2 categories are tied.

Best OverallInnoviva, Inc. (INVA)Leads 4 of 6 categories
Loading custom metrics...

SMTI vs NVCR vs INVA vs HOLX vs BDX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is SMTI or NVCR or INVA or HOLX or BDX a better buy right now?

For growth investors, Sanara MedTech Inc.

(SMTI) is the stronger pick with 19. 0% revenue growth year-over-year, versus 1. 7% for Hologic, Inc. (HOLX). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (7. 3x forward), making it the more compelling value choice. Analysts rate Sanara MedTech Inc. (SMTI) a "Buy" — based on 3 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — SMTI or NVCR or INVA or HOLX or BDX?

On trailing P/E, Innoviva, Inc.

(INVA) is the cheapest at 6. 9x versus Hologic, Inc. at 30. 5x. On forward P/E, Innoviva, Inc. is actually cheaper at 7. 3x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Innoviva, Inc. wins at 0. 71x versus Becton, Dickinson and Company's 0. 72x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — SMTI or NVCR or INVA or HOLX or BDX?

Over the past 5 years, Innoviva, Inc.

(INVA) delivered a total return of +94. 5%, compared to -90. 2% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: SMTI returned +206. 7% versus NVCR's +38. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — SMTI or NVCR or INVA or HOLX or BDX?

By beta (market sensitivity over 5 years), Innoviva, Inc.

(INVA) is the lower-risk stock at 0. 11β versus NovoCure Limited's 2. 15β — meaning NVCR is approximately 1787% more volatile than INVA relative to the S&P 500. On balance sheet safety, Innoviva, Inc. (INVA) carries a lower debt/equity ratio of 23% versus 8% for Sanara MedTech Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — SMTI or NVCR or INVA or HOLX or BDX?

By revenue growth (latest reported year), Sanara MedTech Inc.

(SMTI) is pulling ahead at 19. 0% versus 1. 7% for Hologic, Inc. (HOLX). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -282. 5% for Sanara MedTech Inc.. Over a 3-year CAGR, SMTI leads at 31. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — SMTI or NVCR or INVA or HOLX or BDX?

Innoviva, Inc.

(INVA) is the more profitable company, earning 63. 8% net margin versus -36. 4% for Sanara MedTech Inc. — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — SMTI leads at 92. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is SMTI or NVCR or INVA or HOLX or BDX more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Innoviva, Inc. (INVA) is the more undervalued stock at a PEG of 0. 71x versus Becton, Dickinson and Company's 0. 72x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Innoviva, Inc. (INVA) trades at 7. 3x forward P/E versus 160. 0x for Sanara MedTech Inc. — 152. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVCR: 87. 3% to $33. 50.

08

Which pays a better dividend — SMTI or NVCR or INVA or HOLX or BDX?

In this comparison, BDX (2.

8% yield) pays a dividend. SMTI, NVCR, INVA, HOLX do not pay a meaningful dividend and should not be held primarily for income.

09

Is SMTI or NVCR or INVA or HOLX or BDX better for a retirement portfolio?

For long-horizon retirement investors, Becton, Dickinson and Company (BDX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

62), 2. 8% yield). NovoCure Limited (NVCR) carries a higher beta of 2. 15 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BDX: +76. 4%, NVCR: +38. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between SMTI and NVCR and INVA and HOLX and BDX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: SMTI is a small-cap high-growth stock; NVCR is a small-cap quality compounder stock; INVA is a small-cap high-growth stock; HOLX is a mid-cap quality compounder stock; BDX is a mid-cap quality compounder stock. BDX pays a dividend while SMTI, NVCR, INVA, HOLX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
  • Gross Margin > 55%
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(SMTI: 4.6% · NVCR: 12.3%)

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