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STE vs IART vs HOLX vs MMSI vs BDX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
STE
STERIS plc

Medical - Devices

HealthcareNYSE • IE
Market Cap$21.00B
5Y Perf.+25.1%
IART
Integra LifeSciences Holdings Corporation

Medical - Devices

HealthcareNASDAQ • US
Market Cap$1.06B
5Y Perf.-73.3%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+42.6%
MMSI
Merit Medical Systems, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$3.72B
5Y Perf.+36.2%
BDX
Becton, Dickinson and Company

Medical - Instruments & Supplies

HealthcareNYSE • US
Market Cap$55.53B
5Y Perf.+0.4%

STE vs IART vs HOLX vs MMSI vs BDX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
STE logoSTE
IART logoIART
HOLX logoHOLX
MMSI logoMMSI
BDX logoBDX
IndustryMedical - DevicesMedical - DevicesMedical - Instruments & SuppliesMedical - Instruments & SuppliesMedical - Instruments & Supplies
Market Cap$21.00B$1.06B$16.97B$3.72B$55.53B
Revenue (TTM)$5.83B$1.64B$4.13B$1.54B$21.36B
Net Income (TTM)$708M$-496M$544M$139M$1.14B
Gross Margin44.1%39.6%52.8%48.7%46.5%
Operating Margin17.2%5.8%17.5%12.2%10.6%
Forward P/E20.3x5.8x17.2x15.1x11.9x
Total Debt$2.20B$2.03B$2.63B$898M$19.18B
Cash & Equiv.$172M$235M$1.96B$449M$851M

STE vs IART vs HOLX vs MMSI vs BDXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

STE
IART
HOLX
MMSI
BDX
StockMay 20May 26Return
STERIS plc (STE)100125.1+25.1%
Integra LifeScience… (IART)10026.7-73.3%
Hologic, Inc. (HOLX)100142.6+42.6%
Merit Medical Syste… (MMSI)100136.2+36.2%
Becton, Dickinson a… (BDX)100100.4+0.4%

Price return only. Dividends and distributions are not included.

Quick Verdict: STE vs IART vs HOLX vs MMSI vs BDX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: STE and HOLX are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Hologic, Inc. is the stronger pick specifically for profitability and margin quality and capital preservation and lower volatility. IART, MMSI, and BDX also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
STE
STERIS plc
The Long-Run Compounder

STE has the current edge in this matchup, primarily because of its strength in long-term compounding.

  • 220.0% 10Y total return vs HOLX's 124.3%
  • 1.0% yield, 14-year raise streak, vs BDX's 2.7%, (3 stocks pay no dividend)
  • 6.7% ROA vs IART's -13.7%, ROIC 7.2% vs 1.7%
Best for: long-term compounding
IART
Integra LifeSciences Holdings Corporation
The Value Play

IART ranks third and is worth considering specifically for value.

  • Lower P/E (5.8x vs 17.2x)
Best for: value
HOLX
Hologic, Inc.
The Defensive Pick

HOLX is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.

  • Lower volatility, beta 0.41, Low D/E 52.0%, current ratio 3.75x
  • 13.2% margin vs IART's -30.1%
  • Beta 0.41 vs IART's 2.34, lower leverage
Best for: sleep-well-at-night
MMSI
Merit Medical Systems, Inc.
The Growth Play

MMSI is the clearest fit if your priority is growth exposure.

  • Rev growth 11.7%, EPS growth 4.9%, 3Y rev CAGR 9.6%
  • 11.7% revenue growth vs IART's 1.5%
Best for: growth exposure
BDX
Becton, Dickinson and Company
The Income Pick

BDX is the clearest fit if your priority is income & stability and valuation efficiency.

  • Dividend streak 1 yrs, beta 0.66, yield 2.7%
  • PEG 0.72 vs STE's 3.75
  • Beta 0.66, yield 2.7%, current ratio 1.11x
  • +51.8% vs MMSI's -33.8%
Best for: income & stability and valuation efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthMMSI logoMMSI11.7% revenue growth vs IART's 1.5%
ValueIART logoIARTLower P/E (5.8x vs 17.2x)
Quality / MarginsHOLX logoHOLX13.2% margin vs IART's -30.1%
Stability / SafetyHOLX logoHOLXBeta 0.41 vs IART's 2.34, lower leverage
DividendsSTE logoSTE1.0% yield, 14-year raise streak, vs BDX's 2.7%, (3 stocks pay no dividend)
Momentum (1Y)BDX logoBDX+51.8% vs MMSI's -33.8%
Efficiency (ROA)STE logoSTE6.7% ROA vs IART's -13.7%, ROIC 7.2% vs 1.7%

STE vs IART vs HOLX vs MMSI vs BDX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

STESTERIS plc
FY 2025
Product
52.6%$2.9B
Service
47.4%$2.6B
IARTIntegra LifeSciences Holdings Corporation
FY 2025
Codman Specialty Surgical
73.4%$1.2B
Tissue Technologies
26.6%$435M
HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
MMSIMerit Medical Systems, Inc.
FY 2025
Cardiovascular
95.2%$1.4B
Endoscopy
4.8%$73M
BDXBecton, Dickinson and Company
FY 2025
Medical
52.5%$11.5B
Interventional
23.9%$5.2B
Life Sciences
23.7%$5.2B

STE vs IART vs HOLX vs MMSI vs BDX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLSTELAGGINGBDX

Income & Cash Flow (Last 12 Months)

HOLX leads this category, winning 4 of 6 comparable metrics.

BDX is the larger business by revenue, generating $21.4B annually — 13.9x MMSI's $1.5B. HOLX is the more profitable business, keeping 13.2% of every revenue dollar as net income compared to IART's -30.1%. On growth, STE holds the edge at +9.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricSTE logoSTESTERIS plcIART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…BDX logoBDXBecton, Dickinson…
RevenueTrailing 12 months$5.8B$1.6B$4.1B$1.5B$21.4B
EBITDAEarnings before interest/tax$1.4B$209M$974M$290M$4.2B
Net IncomeAfter-tax profit$708M-$496M$544M$139M$1.1B
Free Cash FlowCash after capex$917M-$10M$1000M$274M$3.1B
Gross MarginGross profit ÷ Revenue+44.1%+39.6%+52.8%+48.7%+46.5%
Operating MarginEBIT ÷ Revenue+17.2%+5.8%+17.5%+12.2%+10.6%
Net MarginNet income ÷ Revenue+12.1%-30.1%+13.2%+9.0%+5.3%
FCF MarginFCF ÷ Revenue+15.7%-0.6%+24.2%+17.8%+14.7%
Rev. Growth (YoY)Latest quarter vs prior year+9.2%+2.4%+2.5%+7.8%-10.6%
EPS Growth (YoY)Latest quarter vs prior year+12.0%+81.8%-9.2%+38.8%-2.0%
HOLX leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

IART leads this category, winning 5 of 7 comparable metrics.

At 26.3x trailing earnings, BDX trades at a 24% valuation discount to STE's 34.5x P/E. Adjusting for growth (PEG ratio), BDX offers better value at 1.59x vs STE's 6.35x — a lower PEG means you pay less per unit of expected earnings growth.

MetricSTE logoSTESTERIS plcIART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…BDX logoBDXBecton, Dickinson…
Market CapShares × price$21.0B$1.1B$17.0B$3.7B$55.5B
Enterprise ValueMkt cap + debt − cash$23.0B$2.9B$17.6B$4.2B$73.9B
Trailing P/EPrice ÷ TTM EPS34.46x-2.01x30.53x29.26x26.29x
Forward P/EPrice ÷ next-FY EPS est.20.34x5.77x17.21x15.05x11.90x
PEG RatioP/E ÷ EPS growth rate6.35x1.59x
EV / EBITDAEnterprise value multiple17.15x13.01x17.39x13.06x14.65x
Price / SalesMarket cap ÷ Revenue3.85x0.65x4.14x2.45x2.54x
Price / BookPrice ÷ Book value/share3.20x1.00x3.43x2.38x1.73x
Price / FCFMarket cap ÷ FCF27.00x18.44x17.24x20.80x
IART leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

STE leads this category, winning 5 of 9 comparable metrics.

HOLX delivers a 11.0% return on equity — every $100 of shareholder capital generates $11 in annual profit, vs $-48 for IART. STE carries lower financial leverage with a 0.33x debt-to-equity ratio, signaling a more conservative balance sheet compared to IART's 1.95x. On the Piotroski fundamental quality scale (0–9), STE scores 8/9 vs IART's 5/9, reflecting strong financial health.

MetricSTE logoSTESTERIS plcIART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…BDX logoBDXBecton, Dickinson…
ROE (TTM)Return on equity+9.9%-47.6%+11.0%+8.9%+4.5%
ROA (TTM)Return on assets+6.7%-13.7%+6.1%+5.2%+2.1%
ROICReturn on invested capital+7.2%+1.7%+9.4%+7.2%+4.3%
ROCEReturn on capital employed+9.0%+2.2%+8.8%+7.9%+5.4%
Piotroski ScoreFundamental quality 0–985767
Debt / EquityFinancial leverage0.33x1.95x0.52x0.57x0.76x
Net DebtTotal debt minus cash$2.0B$1.8B$667M$450M$18.3B
Cash & Equiv.Liquid assets$172M$235M$2.0B$449M$851M
Total DebtShort + long-term debt$2.2B$2.0B$2.6B$898M$19.2B
Interest CoverageEBIT ÷ Interest expense15.94x-10.36x8.00x10.74x4.09x
STE leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

STE leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in BDX five years ago would be worth $11,693 today (with dividends reinvested), compared to $1,827 for IART. Over the past 12 months, BDX leads with a +51.8% total return vs MMSI's -33.8%. The 3-year compound annual growth rate (CAGR) favors STE at 5.3% vs IART's -35.4% — a key indicator of consistent wealth creation.

MetricSTE logoSTESTERIS plcIART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…BDX logoBDXBecton, Dickinson…
YTD ReturnYear-to-date-14.3%+12.9%+1.9%-27.9%+0.7%
1-Year ReturnPast 12 months-3.9%+6.5%+37.1%-33.8%+51.8%
3-Year ReturnCumulative with dividends+16.6%-73.1%-8.5%-26.5%+5.0%
5-Year ReturnCumulative with dividends+5.9%-81.7%+15.8%-3.6%+16.9%
10-Year ReturnCumulative with dividends+220.0%-63.0%+124.3%+214.6%+80.2%
CAGR (3Y)Annualised 3-year return+5.3%-35.4%-2.9%-9.8%+1.6%
STE leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

HOLX leads this category, winning 2 of 2 comparable metrics.

HOLX is the less volatile stock with a 0.41 beta — it tends to amplify market swings less than IART's 2.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs MMSI's 62.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSTE logoSTESTERIS plcIART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…BDX logoBDXBecton, Dickinson…
Beta (5Y)Sensitivity to S&P 5000.67x2.39x0.45x0.66x0.62x
52-Week HighHighest price in past year$269.44$16.49$76.04$100.19$205.52
52-Week LowLowest price in past year$204.81$8.70$52.81$59.74$100.31
% of 52W HighCurrent price vs 52-week peak+79.3%+82.2%+100.0%+62.2%+74.6%
RSI (14)Momentum oscillator 0–10041.275.969.134.932.2
Avg Volume (50D)Average daily shares traded710K858K10.0M769K2.5M
HOLX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — STE and BDX each lead in 1 of 2 comparable metrics.

Analyst consensus: STE as "Buy", IART as "Buy", HOLX as "Hold", MMSI as "Buy", BDX as "Hold". Consensus price targets imply 52.4% upside for MMSI (target: $95) vs -11.5% for IART (target: $12). For income investors, BDX offers the higher dividend yield at 2.72% vs STE's 1.04%.

MetricSTE logoSTESTERIS plcIART logoIARTIntegra LifeScien…HOLX logoHOLXHologic, Inc.MMSI logoMMSIMerit Medical Sys…BDX logoBDXBecton, Dickinson…
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuyHold
Price TargetConsensus 12-month target$256.67$12.00$79.00$95.00$172.85
# AnalystsCovering analysts1326421434
Dividend YieldAnnual dividend ÷ price+1.0%+2.7%
Dividend StreakConsecutive years of raises1401
Dividend / ShareAnnual DPS$2.22$4.17
Buyback YieldShare repurchases ÷ mkt cap+1.0%+0.0%+4.4%0.0%+1.8%
Evenly matched — STE and BDX each lead in 1 of 2 comparable metrics.
Key Takeaway

HOLX leads in 2 of 6 categories (Income & Cash Flow, Risk & Volatility). STE leads in 2 (Profitability & Efficiency, Total Returns). 1 tied.

Best OverallSTERIS plc (STE)Leads 2 of 6 categories
Loading custom metrics...

STE vs IART vs HOLX vs MMSI vs BDX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is STE or IART or HOLX or MMSI or BDX a better buy right now?

For growth investors, Merit Medical Systems, Inc.

(MMSI) is the stronger pick with 11. 7% revenue growth year-over-year, versus 1. 5% for Integra LifeSciences Holdings Corporation (IART). Becton, Dickinson and Company (BDX) offers the better valuation at 26. 3x trailing P/E (11. 9x forward), making it the more compelling value choice. Analysts rate STERIS plc (STE) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — STE or IART or HOLX or MMSI or BDX?

On trailing P/E, Becton, Dickinson and Company (BDX) is the cheapest at 26.

3x versus STERIS plc at 34. 5x. On forward P/E, Integra LifeSciences Holdings Corporation is actually cheaper at 5. 8x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Becton, Dickinson and Company wins at 0. 72x versus STERIS plc's 3. 75x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — STE or IART or HOLX or MMSI or BDX?

Over the past 5 years, Becton, Dickinson and Company (BDX) delivered a total return of +16.

9%, compared to -81. 7% for Integra LifeSciences Holdings Corporation (IART). Over 10 years, the gap is even starker: STE returned +211. 3% versus IART's -62. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — STE or IART or HOLX or MMSI or BDX?

By beta (market sensitivity over 5 years), Hologic, Inc.

(HOLX) is the lower-risk stock at 0. 45β versus Integra LifeSciences Holdings Corporation's 2. 39β — meaning IART is approximately 427% more volatile than HOLX relative to the S&P 500. On balance sheet safety, STERIS plc (STE) carries a lower debt/equity ratio of 33% versus 195% for Integra LifeSciences Holdings Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — STE or IART or HOLX or MMSI or BDX?

By revenue growth (latest reported year), Merit Medical Systems, Inc.

(MMSI) is pulling ahead at 11. 7% versus 1. 5% for Integra LifeSciences Holdings Corporation (IART). On earnings-per-share growth, the picture is similar: STERIS plc grew EPS 62. 7% year-over-year, compared to -73. 6% for Integra LifeSciences Holdings Corporation. Over a 3-year CAGR, MMSI leads at 9. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — STE or IART or HOLX or MMSI or BDX?

Hologic, Inc.

(HOLX) is the more profitable company, earning 13. 8% net margin versus -31. 6% for Integra LifeSciences Holdings Corporation — meaning it keeps 13. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HOLX leads at 17. 4% versus 4. 2% for IART. At the gross margin level — before operating expenses — HOLX leads at 61. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is STE or IART or HOLX or MMSI or BDX more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Becton, Dickinson and Company (BDX) is the more undervalued stock at a PEG of 0. 72x versus STERIS plc's 3. 75x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Integra LifeSciences Holdings Corporation (IART) trades at 5. 8x forward P/E versus 20. 3x for STERIS plc — 14. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for MMSI: 52. 4% to $95. 00.

08

Which pays a better dividend — STE or IART or HOLX or MMSI or BDX?

In this comparison, BDX (2.

7% yield), STE (1. 0% yield) pay a dividend. IART, HOLX, MMSI do not pay a meaningful dividend and should not be held primarily for income.

09

Is STE or IART or HOLX or MMSI or BDX better for a retirement portfolio?

For long-horizon retirement investors, STERIS plc (STE) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

67), 1. 0% yield, +211. 3% 10Y return). Integra LifeSciences Holdings Corporation (IART) carries a higher beta of 2. 39 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (STE: +211. 3%, IART: -62. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between STE and IART and HOLX and MMSI and BDX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

STE, BDX pay a dividend while IART, HOLX, MMSI do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Revenue Growth>
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(STE: 9.2% · IART: 2.4%)

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