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TELA vs OSUR vs BDX vs HOLX vs ISRG

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TELA
TELA Bio, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$44M
5Y Perf.-92.0%
OSUR
OraSure Technologies, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$225M
5Y Perf.-78.5%
BDX
Becton, Dickinson and Company

Medical - Instruments & Supplies

HealthcareNYSE • US
Market Cap$55.53B
5Y Perf.+3.0%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+42.6%
ISRG
Intuitive Surgical, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$161.07B
5Y Perf.+134.6%

TELA vs OSUR vs BDX vs HOLX vs ISRG — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TELA logoTELA
OSUR logoOSUR
BDX logoBDX
HOLX logoHOLX
ISRG logoISRG
IndustryMedical - DevicesMedical - Instruments & SuppliesMedical - Instruments & SuppliesMedical - Instruments & SuppliesMedical - Instruments & Supplies
Market Cap$44M$225M$55.53B$16.97B$161.07B
Revenue (TTM)$77M$85M$21.36B$4.13B$10.58B
Net Income (TTM)$-39M$-53M$1.14B$544M$2.98B
Gross Margin67.2%38.8%46.5%52.8%66.3%
Operating Margin-46.0%-58.6%10.6%17.5%30.5%
Forward P/E12.3x17.2x43.8x
Total Debt$43M$13M$19.18B$2.63B$303M
Cash & Equiv.$53M$199K$851M$1.96B$3.37B

TELA vs OSUR vs BDX vs HOLX vs ISRGLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TELA
OSUR
BDX
HOLX
ISRG
StockMay 20May 26Return
TELA Bio, Inc. (TELA)1008.0-92.0%
OraSure Technologie… (OSUR)10021.5-78.5%
Becton, Dickinson a… (BDX)100103.0+3.0%
Hologic, Inc. (HOLX)100142.6+42.6%
Intuitive Surgical,… (ISRG)100234.6+134.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: TELA vs OSUR vs BDX vs HOLX vs ISRG

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: BDX and ISRG are tied at the top with 3 categories each (5-stock set) — the right choice depends on your priorities. Intuitive Surgical, Inc. is the stronger pick specifically for growth and revenue expansion and profitability and margin quality. HOLX also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
TELA
TELA Bio, Inc.
The Growth Play

TELA is the clearest fit if your priority is growth exposure and defensive.

  • Rev growth 18.6%, EPS growth 34.8%, 3Y rev CAGR 33.0%
  • Beta 0.57, current ratio 5.01x
Best for: growth exposure and defensive
OSUR
OraSure Technologies, Inc.
The Income Pick

OSUR is the clearest fit if your priority is income & stability.

  • Dividend streak 2 yrs, beta 1.45
Best for: income & stability
BDX
Becton, Dickinson and Company
The Value Pick

BDX carries the broadest edge in this set and is the clearest fit for valuation efficiency.

  • PEG 0.74 vs ISRG's 2.01
  • Lower P/E (12.3x vs 43.8x), PEG 0.74 vs 2.01
  • 2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend
  • +51.8% vs ISRG's -15.4%
Best for: valuation efficiency
HOLX
Hologic, Inc.
The Defensive Pick

HOLX ranks third and is worth considering specifically for sleep-well-at-night.

  • Lower volatility, beta 0.41, Low D/E 52.0%, current ratio 3.75x
  • Beta 0.41 vs OSUR's 1.45
Best for: sleep-well-at-night
ISRG
Intuitive Surgical, Inc.
The Long-Run Compounder

ISRG is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 5.5% 10Y total return vs HOLX's 124.3%
  • 20.5% revenue growth vs OSUR's -38.1%
  • 28.2% margin vs OSUR's -61.9%
  • 14.8% ROA vs TELA's -53.1%, ROIC 15.0% vs -151.6%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthISRG logoISRG20.5% revenue growth vs OSUR's -38.1%
ValueBDX logoBDXLower P/E (12.3x vs 43.8x), PEG 0.74 vs 2.01
Quality / MarginsISRG logoISRG28.2% margin vs OSUR's -61.9%
Stability / SafetyHOLX logoHOLXBeta 0.41 vs OSUR's 1.45
DividendsBDX logoBDX2.7% yield; 1-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)BDX logoBDX+51.8% vs ISRG's -15.4%
Efficiency (ROA)ISRG logoISRG14.8% ROA vs TELA's -53.1%, ROIC 15.0% vs -151.6%

TELA vs OSUR vs BDX vs HOLX vs ISRG — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TELATELA Bio, Inc.

Segment breakdown not available.

OSUROraSure Technologies, Inc.
FY 2025
Product And Services
94.8%$109M
Other Revenues
5.2%$6M
BDXBecton, Dickinson and Company
FY 2025
Medical
52.5%$11.5B
Interventional
23.9%$5.2B
Life Sciences
23.7%$5.2B
HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
ISRGIntuitive Surgical, Inc.
FY 2025
Instruments and Accessories
59.8%$6.0B
Systems
24.6%$2.5B
Services
15.6%$1.6B

TELA vs OSUR vs BDX vs HOLX vs ISRG — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLISRGLAGGINGTELA

Income & Cash Flow (Last 12 Months)

ISRG leads this category, winning 4 of 6 comparable metrics.

BDX is the larger business by revenue, generating $21.4B annually — 277.3x TELA's $77M. ISRG is the more profitable business, keeping 28.2% of every revenue dollar as net income compared to OSUR's -61.9%. On growth, ISRG holds the edge at +23.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTELA logoTELATELA Bio, Inc.OSUR logoOSUROraSure Technolog…BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.ISRG logoISRGIntuitive Surgica…
RevenueTrailing 12 months$77M$85M$21.4B$4.1B$10.6B
EBITDAEarnings before interest/tax-$34M-$45M$4.2B$974M$3.8B
Net IncomeAfter-tax profit-$39M-$53M$1.1B$544M$3.0B
Free Cash FlowCash after capex-$32M-$33M$3.1B$1000M$2.8B
Gross MarginGross profit ÷ Revenue+67.2%+38.8%+46.5%+52.8%+66.3%
Operating MarginEBIT ÷ Revenue-46.0%-58.6%+10.6%+17.5%+30.5%
Net MarginNet income ÷ Revenue-50.6%-61.9%+5.3%+13.2%+28.2%
FCF MarginFCF ÷ Revenue-40.9%-38.9%+14.7%+24.2%+26.8%
Rev. Growth (YoY)Latest quarter vs prior year+9.1%-99.9%-10.6%+2.5%+23.0%
EPS Growth (YoY)Latest quarter vs prior year+54.8%-52.4%-2.0%-9.2%+18.8%
ISRG leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

BDX leads this category, winning 3 of 7 comparable metrics.

At 26.3x trailing earnings, BDX trades at a 54% valuation discount to ISRG's 57.6x P/E. Adjusting for growth (PEG ratio), BDX offers better value at 1.59x vs ISRG's 2.65x — a lower PEG means you pay less per unit of expected earnings growth.

MetricTELA logoTELATELA Bio, Inc.OSUR logoOSUROraSure Technolog…BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.ISRG logoISRGIntuitive Surgica…
Market CapShares × price$44M$225M$55.5B$17.0B$161.1B
Enterprise ValueMkt cap + debt − cash$35M$238M$73.9B$17.6B$158.0B
Trailing P/EPrice ÷ TTM EPS-0.83x-3.33x26.29x30.53x57.62x
Forward P/EPrice ÷ next-FY EPS est.12.27x17.21x43.84x
PEG RatioP/E ÷ EPS growth rate1.59x2.65x
EV / EBITDAEnterprise value multiple14.65x17.39x43.62x
Price / SalesMarket cap ÷ Revenue0.64x1.96x2.54x4.14x16.00x
Price / BookPrice ÷ Book value/share1.10x0.67x1.73x3.43x9.17x
Price / FCFMarket cap ÷ FCF20.80x18.44x64.67x
BDX leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

ISRG leads this category, winning 6 of 9 comparable metrics.

ISRG delivers a 16.9% return on equity — every $100 of shareholder capital generates $17 in annual profit, vs $-3 for TELA. ISRG carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to TELA's 1.51x. On the Piotroski fundamental quality scale (0–9), BDX scores 7/9 vs OSUR's 3/9, reflecting strong financial health.

MetricTELA logoTELATELA Bio, Inc.OSUR logoOSUROraSure Technolog…BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.ISRG logoISRGIntuitive Surgica…
ROE (TTM)Return on equity-2.7%-15.1%+4.5%+11.0%+16.9%
ROA (TTM)Return on assets-53.1%-12.8%+2.1%+6.1%+14.8%
ROICReturn on invested capital-151.6%-20.0%+4.3%+9.4%+15.0%
ROCEReturn on capital employed-51.4%-16.8%+5.4%+8.8%+16.5%
Piotroski ScoreFundamental quality 0–943776
Debt / EquityFinancial leverage1.51x0.04x0.76x0.52x0.02x
Net DebtTotal debt minus cash-$10M$13M$18.3B$667M-$3.1B
Cash & Equiv.Liquid assets$53M$199,278$851M$2.0B$3.4B
Total DebtShort + long-term debt$43M$13M$19.2B$2.6B$303M
Interest CoverageEBIT ÷ Interest expense-6.99x4.09x8.00x
ISRG leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ISRG leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ISRG five years ago would be worth $15,873 today (with dividends reinvested), compared to $853 for TELA. Over the past 12 months, BDX leads with a +51.8% total return vs ISRG's -15.4%. The 3-year compound annual growth rate (CAGR) favors ISRG at 14.4% vs TELA's -51.9% — a key indicator of consistent wealth creation.

MetricTELA logoTELATELA Bio, Inc.OSUR logoOSUROraSure Technolog…BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.ISRG logoISRGIntuitive Surgica…
YTD ReturnYear-to-date-3.5%+31.5%+0.7%+1.9%-19.3%
1-Year ReturnPast 12 months+15.8%+12.2%+51.8%+37.1%-15.4%
3-Year ReturnCumulative with dividends-88.9%-55.2%+5.0%-8.5%+49.6%
5-Year ReturnCumulative with dividends-91.5%-68.3%+16.9%+15.8%+58.7%
10-Year ReturnCumulative with dividends-91.8%-53.1%+80.2%+124.3%+554.2%
CAGR (3Y)Annualised 3-year return-51.9%-23.5%+1.6%-2.9%+14.4%
ISRG leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

HOLX leads this category, winning 2 of 2 comparable metrics.

HOLX is the less volatile stock with a 0.41 beta — it tends to amplify market swings less than OSUR's 1.45 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs TELA's 50.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTELA logoTELATELA Bio, Inc.OSUR logoOSUROraSure Technolog…BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.ISRG logoISRGIntuitive Surgica…
Beta (5Y)Sensitivity to S&P 5000.57x1.45x0.66x0.41x1.02x
52-Week HighHighest price in past year$2.20$3.82$205.52$76.04$603.88
52-Week LowLowest price in past year$0.50$2.08$100.31$52.81$427.84
% of 52W HighCurrent price vs 52-week peak+50.0%+81.9%+74.6%+100.0%+75.1%
RSI (14)Momentum oscillator 0–10062.747.132.269.142.4
Avg Volume (50D)Average daily shares traded188K473K2.5M10.0M1.8M
HOLX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

OSUR leads this category, winning 1 of 1 comparable metric.

Analyst consensus: OSUR as "Hold", BDX as "Buy", HOLX as "Hold", ISRG as "Buy". Consensus price targets imply 37.3% upside for ISRG (target: $623) vs 3.9% for HOLX (target: $79). BDX is the only dividend payer here at 2.72% yield — a key consideration for income-focused portfolios.

MetricTELA logoTELATELA Bio, Inc.OSUR logoOSUROraSure Technolog…BDX logoBDXBecton, Dickinson…HOLX logoHOLXHologic, Inc.ISRG logoISRGIntuitive Surgica…
Analyst RatingConsensus buy/hold/sellHoldBuyHoldBuy
Price TargetConsensus 12-month target$4.00$172.85$79.00$622.60
# AnalystsCovering analysts13334255
Dividend YieldAnnual dividend ÷ price+2.7%
Dividend StreakConsecutive years of raises21
Dividend / ShareAnnual DPS$4.17
Buyback YieldShare repurchases ÷ mkt cap0.0%+6.7%+1.8%+4.4%+1.4%
OSUR leads this category, winning 1 of 1 comparable metric.
Key Takeaway

ISRG leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BDX leads in 1 (Valuation Metrics).

Best OverallIntuitive Surgical, Inc. (ISRG)Leads 3 of 6 categories
Loading custom metrics...

TELA vs OSUR vs BDX vs HOLX vs ISRG: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is TELA or OSUR or BDX or HOLX or ISRG a better buy right now?

For growth investors, Intuitive Surgical, Inc.

(ISRG) is the stronger pick with 20. 5% revenue growth year-over-year, versus -38. 1% for OraSure Technologies, Inc. (OSUR). Becton, Dickinson and Company (BDX) offers the better valuation at 26. 3x trailing P/E (12. 3x forward), making it the more compelling value choice. Analysts rate Becton, Dickinson and Company (BDX) a "Buy" — based on 33 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — TELA or OSUR or BDX or HOLX or ISRG?

On trailing P/E, Becton, Dickinson and Company (BDX) is the cheapest at 26.

3x versus Intuitive Surgical, Inc. at 57. 6x. On forward P/E, Becton, Dickinson and Company is actually cheaper at 12. 3x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Becton, Dickinson and Company wins at 0. 74x versus Intuitive Surgical, Inc. 's 2. 01x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — TELA or OSUR or BDX or HOLX or ISRG?

Over the past 5 years, Intuitive Surgical, Inc.

(ISRG) delivered a total return of +58. 7%, compared to -91. 5% for TELA Bio, Inc. (TELA). Over 10 years, the gap is even starker: ISRG returned +554. 2% versus TELA's -91. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — TELA or OSUR or BDX or HOLX or ISRG?

By beta (market sensitivity over 5 years), Hologic, Inc.

(HOLX) is the lower-risk stock at 0. 41β versus OraSure Technologies, Inc. 's 1. 45β — meaning OSUR is approximately 253% more volatile than HOLX relative to the S&P 500. On balance sheet safety, Intuitive Surgical, Inc. (ISRG) carries a lower debt/equity ratio of 2% versus 151% for TELA Bio, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — TELA or OSUR or BDX or HOLX or ISRG?

By revenue growth (latest reported year), Intuitive Surgical, Inc.

(ISRG) is pulling ahead at 20. 5% versus -38. 1% for OraSure Technologies, Inc. (OSUR). On earnings-per-share growth, the picture is similar: TELA Bio, Inc. grew EPS 34. 8% year-over-year, compared to -261. 5% for OraSure Technologies, Inc.. Over a 3-year CAGR, TELA leads at 33. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — TELA or OSUR or BDX or HOLX or ISRG?

Intuitive Surgical, Inc.

(ISRG) is the more profitable company, earning 28. 4% net margin versus -59. 8% for OraSure Technologies, Inc. — meaning it keeps 28. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ISRG leads at 29. 3% versus -59. 2% for OSUR. At the gross margin level — before operating expenses — TELA leads at 67. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is TELA or OSUR or BDX or HOLX or ISRG more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Becton, Dickinson and Company (BDX) is the more undervalued stock at a PEG of 0. 74x versus Intuitive Surgical, Inc. 's 2. 01x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Becton, Dickinson and Company (BDX) trades at 12. 3x forward P/E versus 43. 8x for Intuitive Surgical, Inc. — 31. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ISRG: 37. 3% to $622. 60.

08

Which pays a better dividend — TELA or OSUR or BDX or HOLX or ISRG?

In this comparison, BDX (2.

7% yield) pays a dividend. TELA, OSUR, HOLX, ISRG do not pay a meaningful dividend and should not be held primarily for income.

09

Is TELA or OSUR or BDX or HOLX or ISRG better for a retirement portfolio?

For long-horizon retirement investors, Becton, Dickinson and Company (BDX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

66), 2. 7% yield). Both have compounded well over 10 years (BDX: +80. 2%, OSUR: -53. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between TELA and OSUR and BDX and HOLX and ISRG?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: TELA is a small-cap high-growth stock; OSUR is a small-cap quality compounder stock; BDX is a mid-cap quality compounder stock; HOLX is a mid-cap quality compounder stock; ISRG is a mid-cap high-growth stock. BDX pays a dividend while TELA, OSUR, HOLX, ISRG do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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TELA

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  • Market Cap > $100B
  • Revenue Growth > 5%
  • Gross Margin > 40%
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OSUR

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 23%
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BDX

Income & Dividend Stock

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 5%
  • Dividend Yield > 1.0%
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HOLX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 7%
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ISRG

High-Growth Quality Leader

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 11%
  • Net Margin > 16%
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Revenue Growth>
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(TELA: 9.1% · OSUR: -99.9%)

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