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TENX vs IMVT vs ARDX vs ACAD vs IQV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TENX
Tenax Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$69M
5Y Perf.-99.5%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.88B
5Y Perf.+12.8%
ARDX
Ardelyx, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.66B
5Y Perf.+270.5%
ACAD
ACADIA Pharmaceuticals Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.84B
5Y Perf.-54.9%
IQV
IQVIA Holdings Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$30.33B
5Y Perf.+19.5%

TENX vs IMVT vs ARDX vs ACAD vs IQV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TENX logoTENX
IMVT logoIMVT
ARDX logoARDX
ACAD logoACAD
IQV logoIQV
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyMedical - Diagnostics & Research
Market Cap$69M$5.88B$1.66B$3.84B$30.33B
Revenue (TTM)$0.00$0.00$428M$1.10B$16.63B
Net Income (TTM)$-43M$-464M$-58M$376M$1.39B
Gross Margin91.9%91.5%26.1%
Operating Margin-8.7%7.4%13.9%
Forward P/E55.6x14.0x
Total Debt$0.00$98K$212M$52M$16.17B
Cash & Equiv.$95M$714M$68M$178M$1.98B

TENX vs IMVT vs ARDX vs ACAD vs IQVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TENX
IMVT
ARDX
ACAD
IQV
StockMay 20May 26Return
Tenax Therapeutics,… (TENX)1000.5-99.5%
Immunovant, Inc. (IMVT)100112.8+12.8%
Ardelyx, Inc. (ARDX)100370.5+270.5%
ACADIA Pharmaceutic… (ACAD)10045.1-54.9%
IQVIA Holdings Inc. (IQV)100119.5+19.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: TENX vs IMVT vs ARDX vs ACAD vs IQV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: TENX and ACAD are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. ACADIA Pharmaceuticals Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. IMVT and IQV also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
TENX
Tenax Therapeutics, Inc.
The Income Pick

TENX has the current edge in this matchup, primarily because of its strength in income & stability and sleep-well-at-night.

  • Dividend streak 1 yrs, beta 0.77
  • Lower volatility, beta 0.77, current ratio 20.60x
  • Beta 0.77, current ratio 20.60x
  • 428.0% revenue growth vs IMVT's -21.3%
Best for: income & stability and sleep-well-at-night
IMVT
Immunovant, Inc.
The Momentum Pick

IMVT ranks third and is worth considering specifically for momentum.

  • +102.4% vs IQV's +16.6%
Best for: momentum
ARDX
Ardelyx, Inc.
The Growth Play

ARDX is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth 22.1%, EPS growth -52.9%, 3Y rev CAGR 98.4%
  • 253.1% 10Y total return vs IMVT's 190.9%
Best for: growth exposure and long-term compounding
ACAD
ACADIA Pharmaceuticals Inc.
The Quality Compounder

ACAD is the #2 pick in this set and the best alternative if quality and efficiency is your priority.

  • 34.3% margin vs ARDX's -13.6%
  • 26.2% ROA vs IMVT's -44.1%
Best for: quality and efficiency
IQV
IQVIA Holdings Inc.
The Value Play

IQV is the clearest fit if your priority is value.

  • Lower P/E (14.0x vs 55.6x)
Best for: value
See the full category breakdown
CategoryWinnerWhy
GrowthTENX logoTENX428.0% revenue growth vs IMVT's -21.3%
ValueIQV logoIQVLower P/E (14.0x vs 55.6x)
Quality / MarginsACAD logoACAD34.3% margin vs ARDX's -13.6%
Stability / SafetyTENX logoTENXBeta 0.77 vs IMVT's 1.36
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)IMVT logoIMVT+102.4% vs IQV's +16.6%
Efficiency (ROA)ACAD logoACAD26.2% ROA vs IMVT's -44.1%

TENX vs IMVT vs ARDX vs ACAD vs IQV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TENXTenax Therapeutics, Inc.
FY 2013
United States
100.0%$46,016
IMVTImmunovant, Inc.

Segment breakdown not available.

ARDXArdelyx, Inc.
FY 2025
Product
57.5%$378M
Product, IBSRELA
41.7%$274M
License
0.8%$5M
ACADACADIA Pharmaceuticals Inc.
FY 2018
Product
100.0%$224M
IQVIQVIA Holdings Inc.
FY 2025
Research And Development Solutions
54.5%$8.9B
Technology And Analytics Solutions
40.6%$6.6B
Contract Sales And Medical Solutions
4.8%$788M

TENX vs IMVT vs ARDX vs ACAD vs IQV — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLIQVLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

Evenly matched — ARDX and ACAD each lead in 2 of 6 comparable metrics.

IQV and IMVT operate at a comparable scale, with $16.6B and $0 in trailing revenue. ACAD is the more profitable business, keeping 34.3% of every revenue dollar as net income compared to ARDX's -13.6%. On growth, ARDX holds the edge at +27.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTENX logoTENXTenax Therapeutic…IMVT logoIMVTImmunovant, Inc.ARDX logoARDXArdelyx, Inc.ACAD logoACADACADIA Pharmaceut…IQV logoIQVIQVIA Holdings In…
RevenueTrailing 12 months$0$0$428M$1.1B$16.6B
EBITDAEarnings before interest/tax-$43M-$487M-$35M$96M$3.5B
Net IncomeAfter-tax profit-$43M-$464M-$58M$376M$1.4B
Free Cash FlowCash after capex-$26M-$423M-$37M$212M$2.7B
Gross MarginGross profit ÷ Revenue+91.9%+91.5%+26.1%
Operating MarginEBIT ÷ Revenue-8.7%+7.4%+13.9%
Net MarginNet income ÷ Revenue-13.6%+34.3%+8.3%
FCF MarginFCF ÷ Revenue-8.8%+19.4%+16.1%
Rev. Growth (YoY)Latest quarter vs prior year+27.5%+9.7%+8.4%
EPS Growth (YoY)Latest quarter vs prior year-110.5%+19.7%+11.8%-81.8%+15.0%
Evenly matched — ARDX and ACAD each lead in 2 of 6 comparable metrics.

Valuation Metrics

IQV leads this category, winning 4 of 6 comparable metrics.

At 9.8x trailing earnings, ACAD trades at a 57% valuation discount to IQV's 22.8x P/E. On an enterprise value basis, IQV's 13.0x EV/EBITDA is more attractive than ACAD's 26.7x.

MetricTENX logoTENXTenax Therapeutic…IMVT logoIMVTImmunovant, Inc.ARDX logoARDXArdelyx, Inc.ACAD logoACADACADIA Pharmaceut…IQV logoIQVIQVIA Holdings In…
Market CapShares × price$69M$5.9B$1.7B$3.8B$30.3B
Enterprise ValueMkt cap + debt − cash-$26M$5.2B$1.8B$3.7B$44.5B
Trailing P/EPrice ÷ TTM EPS-10.14x-10.60x-26.08x9.78x22.79x
Forward P/EPrice ÷ next-FY EPS est.55.62x13.96x
PEG RatioP/E ÷ EPS growth rate0.56x
EV / EBITDAEnterprise value multiple26.71x12.98x
Price / SalesMarket cap ÷ Revenue4.08x3.58x1.86x
Price / BookPrice ÷ Book value/share1.94x6.20x9.79x3.13x4.68x
Price / FCFMarket cap ÷ FCF36.48x14.79x
IQV leads this category, winning 4 of 6 comparable metrics.

Profitability & Efficiency

ACAD leads this category, winning 4 of 9 comparable metrics.

ACAD delivers a 35.6% return on equity — every $100 of shareholder capital generates $36 in annual profit, vs $-47 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), ACAD scores 6/9 vs IMVT's 2/9, reflecting solid financial health.

MetricTENX logoTENXTenax Therapeutic…IMVT logoIMVTImmunovant, Inc.ARDX logoARDXArdelyx, Inc.ACAD logoACADACADIA Pharmaceut…IQV logoIQVIQVIA Holdings In…
ROE (TTM)Return on equity-45.0%-47.1%-38.1%+35.6%+22.1%
ROA (TTM)Return on assets-42.1%-44.1%-11.8%+26.2%+4.7%
ROICReturn on invested capital-10.7%+10.0%+8.7%
ROCEReturn on capital employed-39.0%-66.1%-10.6%+10.1%+11.0%
Piotroski ScoreFundamental quality 0–932364
Debt / EquityFinancial leverage0.00x1.27x0.04x2.44x
Net DebtTotal debt minus cash-$95M-$714M$144M-$126M$14.2B
Cash & Equiv.Liquid assets$95M$714M$68M$178M$2.0B
Total DebtShort + long-term debt$0$98,000$212M$52M$16.2B
Interest CoverageEBIT ÷ Interest expense-847.57x-0.28x3.10x
ACAD leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ARDX leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ARDX five years ago would be worth $41,341 today (with dividends reinvested), compared to $37 for TENX. Over the past 12 months, IMVT leads with a +102.4% total return vs IQV's +16.6%. The 3-year compound annual growth rate (CAGR) favors ARDX at 17.4% vs TENX's -23.4% — a key indicator of consistent wealth creation.

MetricTENX logoTENXTenax Therapeutic…IMVT logoIMVTImmunovant, Inc.ARDX logoARDXArdelyx, Inc.ACAD logoACADACADIA Pharmaceut…IQV logoIQVIQVIA Holdings In…
YTD ReturnYear-to-date+5.5%+11.7%+10.2%-14.3%-20.7%
1-Year ReturnPast 12 months+100.3%+102.4%+86.3%+32.3%+16.6%
3-Year ReturnCumulative with dividends-55.0%+49.8%+61.8%+3.9%-5.9%
5-Year ReturnCumulative with dividends-99.6%+84.4%+313.4%+6.6%-22.8%
10-Year ReturnCumulative with dividends-100.0%+190.9%+253.1%-23.4%+166.6%
CAGR (3Y)Annualised 3-year return-23.4%+14.4%+17.4%+1.3%-2.0%
ARDX leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — TENX and IMVT each lead in 1 of 2 comparable metrics.

TENX is the less volatile stock with a 0.77 beta — it tends to amplify market swings less than IMVT's 1.36 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 96.2% from its 52-week high vs TENX's 63.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTENX logoTENXTenax Therapeutic…IMVT logoIMVTImmunovant, Inc.ARDX logoARDXArdelyx, Inc.ACAD logoACADACADIA Pharmaceut…IQV logoIQVIQVIA Holdings In…
Beta (5Y)Sensitivity to S&P 5000.77x1.36x1.05x1.11x1.32x
52-Week HighHighest price in past year$18.38$30.09$8.40$27.81$247.05
52-Week LowLowest price in past year$5.34$13.36$3.21$14.68$134.65
% of 52W HighCurrent price vs 52-week peak+63.4%+96.2%+80.7%+80.5%+72.3%
RSI (14)Momentum oscillator 0–10036.550.664.853.860.3
Avg Volume (50D)Average daily shares traded537K1.4M3.6M1.7M1.5M
Evenly matched — TENX and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

IQV leads this category, winning 1 of 1 comparable metric.

Analyst consensus: IMVT as "Buy", ARDX as "Buy", ACAD as "Buy", IQV as "Buy". Consensus price targets imply 150.7% upside for ARDX (target: $17) vs 25.2% for IQV (target: $224).

MetricTENX logoTENXTenax Therapeutic…IMVT logoIMVTImmunovant, Inc.ARDX logoARDXArdelyx, Inc.ACAD logoACADACADIA Pharmaceut…IQV logoIQVIQVIA Holdings In…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$45.50$17.00$34.78$223.75
# AnalystsCovering analysts23163744
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises12
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+4.1%
IQV leads this category, winning 1 of 1 comparable metric.
Key Takeaway

IQV leads in 2 of 6 categories (Valuation Metrics, Analyst Outlook). ACAD leads in 1 (Profitability & Efficiency). 2 tied.

Best OverallIQVIA Holdings Inc. (IQV)Leads 2 of 6 categories
Loading custom metrics...

TENX vs IMVT vs ARDX vs ACAD vs IQV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is TENX or IMVT or ARDX or ACAD or IQV a better buy right now?

For growth investors, Ardelyx, Inc.

(ARDX) is the stronger pick with 22. 1% revenue growth year-over-year, versus 5. 9% for IQVIA Holdings Inc. (IQV). ACADIA Pharmaceuticals Inc. (ACAD) offers the better valuation at 9. 8x trailing P/E (55. 6x forward), making it the more compelling value choice. Analysts rate Immunovant, Inc. (IMVT) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — TENX or IMVT or ARDX or ACAD or IQV?

On trailing P/E, ACADIA Pharmaceuticals Inc.

(ACAD) is the cheapest at 9. 8x versus IQVIA Holdings Inc. at 22. 8x. On forward P/E, IQVIA Holdings Inc. is actually cheaper at 14. 0x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — TENX or IMVT or ARDX or ACAD or IQV?

Over the past 5 years, Ardelyx, Inc.

(ARDX) delivered a total return of +313. 4%, compared to -99. 6% for Tenax Therapeutics, Inc. (TENX). Over 10 years, the gap is even starker: ARDX returned +253. 1% versus TENX's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — TENX or IMVT or ARDX or ACAD or IQV?

By beta (market sensitivity over 5 years), Tenax Therapeutics, Inc.

(TENX) is the lower-risk stock at 0. 77β versus Immunovant, Inc. 's 1. 36β — meaning IMVT is approximately 77% more volatile than TENX relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — TENX or IMVT or ARDX or ACAD or IQV?

By revenue growth (latest reported year), Ardelyx, Inc.

(ARDX) is pulling ahead at 22. 1% versus 5. 9% for IQVIA Holdings Inc. (IQV). On earnings-per-share growth, the picture is similar: Tenax Therapeutics, Inc. grew EPS 96. 3% year-over-year, compared to -52. 9% for Ardelyx, Inc.. Over a 3-year CAGR, ARDX leads at 98. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — TENX or IMVT or ARDX or ACAD or IQV?

ACADIA Pharmaceuticals Inc.

(ACAD) is the more profitable company, earning 36. 5% net margin versus -15. 1% for Ardelyx, Inc. — meaning it keeps 36. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IQV leads at 14. 0% versus -10. 1% for ARDX. At the gross margin level — before operating expenses — ACAD leads at 91. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is TENX or IMVT or ARDX or ACAD or IQV more undervalued right now?

On forward earnings alone, IQVIA Holdings Inc.

(IQV) trades at 14. 0x forward P/E versus 55. 6x for ACADIA Pharmaceuticals Inc. — 41. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ARDX: 150. 7% to $17. 00.

08

Which pays a better dividend — TENX or IMVT or ARDX or ACAD or IQV?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is TENX or IMVT or ARDX or ACAD or IQV better for a retirement portfolio?

For long-horizon retirement investors, Tenax Therapeutics, Inc.

(TENX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 77)). Both have compounded well over 10 years (TENX: -100. 0%, IMVT: +190. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between TENX and IMVT and ARDX and ACAD and IQV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: TENX is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; ARDX is a small-cap high-growth stock; ACAD is a small-cap deep-value stock; IQV is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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