TLRY vs IIPR vs CGC vs REFI vs ACB

For growth investors, Aurora Cannabis Inc.

(ACB) is the stronger pick with 27. 0% revenue growth year-over-year, versus -13. 8% for Innovative Industrial Properties, Inc. (IIPR). Chicago Atlantic Real Estate Finance, Inc. (REFI) offers the better valuation at 6. 9x trailing P/E (6. 4x forward), making it the more compelling value choice. Analysts rate Chicago Atlantic Real Estate Finance, Inc. (REFI) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

On trailing P/E, Chicago Atlantic Real Estate Finance, Inc.

(REFI) is the cheapest at 6. 9x versus Aurora Cannabis Inc. at 164. 2x. On forward P/E, Chicago Atlantic Real Estate Finance, Inc. is actually cheaper at 6. 4x.

Over the past 5 years, Chicago Atlantic Real Estate Finance, Inc.

(REFI) delivered a total return of +24. 7%, compared to -99. 6% for Canopy Growth Corporation (CGC). Over 10 years, the gap is even starker: IIPR returned +436. 4% versus CGC's -94. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

By beta (market sensitivity over 5 years), Chicago Atlantic Real Estate Finance, Inc.

(REFI) is the lower-risk stock at 0. 69β versus Tilray Brands, Inc. 's 2. 03β — meaning TLRY is approximately 196% more volatile than REFI relative to the S&P 500. On balance sheet safety, Aurora Cannabis Inc. (ACB) carries a lower debt/equity ratio of 17% versus 72% for Canopy Growth Corporation — giving it more financial flexibility in a downturn.

By revenue growth (latest reported year), Aurora Cannabis Inc.

(ACB) is pulling ahead at 27. 0% versus -13. 8% for Innovative Industrial Properties, Inc. (IIPR). On earnings-per-share growth, the picture is similar: Aurora Cannabis Inc. grew EPS 102. 2% year-over-year, compared to -651. 7% for Tilray Brands, Inc.. Over a 3-year CAGR, ACB leads at 15. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

Chicago Atlantic Real Estate Finance, Inc.

(REFI) is the more profitable company, earning 57. 1% net margin versus -266. 3% for Tilray Brands, Inc. — meaning it keeps 57. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: REFI leads at 57. 1% versus -277. 9% for TLRY. At the gross margin level — before operating expenses — IIPR leads at 88. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

On forward earnings alone, Chicago Atlantic Real Estate Finance, Inc.

(REFI) trades at 6. 4x forward P/E versus 13. 2x for Innovative Industrial Properties, Inc. — 6. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for CGC: 1180. 5% to $14. 47.

In this comparison, REFI (100.

0% yield), IIPR (13. 5% yield) pay a dividend. TLRY, CGC, ACB do not pay a meaningful dividend and should not be held primarily for income.

For long-horizon retirement investors, Innovative Industrial Properties, Inc.

(IIPR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 92), 13. 5% yield, +436. 4% 10Y return). Tilray Brands, Inc. (TLRY) carries a higher beta of 2. 03 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IIPR: +436. 4%, TLRY: -74. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

These companies operate in different sectors (TLRY (Healthcare) and IIPR (Real Estate) and CGC (Healthcare) and REFI (Real Estate) and ACB (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: TLRY is a small-cap quality compounder stock; IIPR is a small-cap deep-value stock; CGC is a small-cap quality compounder stock; REFI is a small-cap high-growth stock; ACB is a small-cap high-growth stock. IIPR, REFI pay a dividend while TLRY, CGC, ACB do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.