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TMO vs DHR vs A vs WAT vs BIO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$173.46B
5Y Perf.+33.7%
DHR
Danaher Corporation

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$123.60B
5Y Perf.+18.2%
A
Agilent Technologies, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$33.27B
5Y Perf.+71.4%
WAT
Waters Corporation

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$20.38B
5Y Perf.+2.1%
BIO
Bio-Rad Laboratories, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$6.94B
5Y Perf.-47.7%

TMO vs DHR vs A vs WAT vs BIO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TMO logoTMO
DHR logoDHR
A logoA
WAT logoWAT
BIO logoBIO
IndustryMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Devices
Market Cap$173.46B$123.60B$33.27B$20.38B$6.94B
Revenue (TTM)$45.20B$24.78B$7.07B$3.77B$2.59B
Net Income (TTM)$6.86B$3.69B$1.29B$449M$169M
Gross Margin39.4%60.7%38.8%55.0%51.9%
Operating Margin17.8%21.0%20.6%17.1%9.2%
Forward P/E18.8x20.7x19.7x23.8x25.0x
Total Debt$40.85B$18.42B$3.35B$1.41B$1.53B
Cash & Equiv.$9.86B$4.62B$1.79B$588M$532M

TMO vs DHR vs A vs WAT vs BIOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TMO
DHR
A
WAT
BIO
StockMay 20May 26Return
Thermo Fisher Scien… (TMO)100133.7+33.7%
Danaher Corporation (DHR)100118.2+18.2%
Agilent Technologie… (A)100133.3+33.3%
Waters Corporation (WAT)100171.4+71.4%
Bio-Rad Laboratorie… (BIO)10052.3-47.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: TMO vs DHR vs A vs WAT vs BIO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: A leads in 3 of 7 categories (5-stock set), making it the strongest pick for profitability and margin quality and dividend income and shareholder returns. Thermo Fisher Scientific Inc. is the stronger pick specifically for valuation and capital efficiency and recent price momentum and sentiment. WAT and BIO also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
TMO
Thermo Fisher Scientific Inc.
The Long-Run Compounder

TMO is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 229.0% 10Y total return vs DHR's 220.9%
  • Lower P/E (18.8x vs 23.8x)
  • +11.0% vs DHR's -10.8%
Best for: long-term compounding
DHR
Danaher Corporation
The Quality Angle

Among these 5 stocks, DHR doesn't own a clear edge in any measured category.

Best for: healthcare exposure
A
Agilent Technologies, Inc.
The Income Pick

A carries the broadest edge in this set and is the clearest fit for income & stability and valuation efficiency.

  • Dividend streak 10 yrs, beta 1.23, yield 0.8%
  • PEG 1.34 vs DHR's 34.15
  • 18.3% margin vs BIO's 6.5%
  • 0.8% yield, 10-year raise streak, vs TMO's 0.4%, (2 stocks pay no dividend)
Best for: income & stability and valuation efficiency
WAT
Waters Corporation
The Growth Play

WAT ranks third and is worth considering specifically for growth exposure.

  • Rev growth 7.0%, EPS growth 0.5%, 3Y rev CAGR 2.1%
  • 7.0% revenue growth vs BIO's 0.7%
Best for: growth exposure
BIO
Bio-Rad Laboratories, Inc.
The Defensive Pick

BIO is the clearest fit if your priority is sleep-well-at-night and defensive.

  • Lower volatility, beta 0.92, Low D/E 20.5%, current ratio 5.62x
  • Beta 0.92, current ratio 5.62x
  • Beta 0.92 vs A's 1.23, lower leverage
Best for: sleep-well-at-night and defensive
See the full category breakdown
CategoryWinnerWhy
GrowthWAT logoWAT7.0% revenue growth vs BIO's 0.7%
ValueTMO logoTMOLower P/E (18.8x vs 23.8x)
Quality / MarginsA logoA18.3% margin vs BIO's 6.5%
Stability / SafetyBIO logoBIOBeta 0.92 vs A's 1.23, lower leverage
DividendsA logoA0.8% yield, 10-year raise streak, vs TMO's 0.4%, (2 stocks pay no dividend)
Momentum (1Y)TMO logoTMO+11.0% vs DHR's -10.8%
Efficiency (ROA)A logoA10.1% ROA vs BIO's 2.2%, ROIC 13.5% vs 2.6%

TMO vs DHR vs A vs WAT vs BIO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B
DHRDanaher Corporation
FY 2025
Revenue from Contract with Customer, Measurement, Recurring
81.9%$20.1B
Revenue from Contract with Customer, Measurement, Nonrecurring
18.1%$4.4B
AAgilent Technologies, Inc.
FY 2025
Agilent CrossLab
41.9%$2.9B
Life Sciences and Applied Markets
39.2%$2.7B
Applied Markets
18.9%$1.3B
WATWaters Corporation
FY 2025
Waters Instrument Systems
34.8%$1.1B
Waters Service
34.1%$1.1B
Chemistry Consumables
19.9%$631M
Ta Instrument Systems
7.7%$244M
Ta Service
3.4%$108M
BIOBio-Rad Laboratories, Inc.
FY 2025
Clinical Diagnostics
60.5%$1.6B
Life Science
39.5%$1.0B

TMO vs DHR vs A vs WAT vs BIO — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLWATLAGGINGTMO

Income & Cash Flow (Last 12 Months)

DHR leads this category, winning 3 of 6 comparable metrics.

TMO is the larger business by revenue, generating $45.2B annually — 17.5x BIO's $2.6B. A is the more profitable business, keeping 18.3% of every revenue dollar as net income compared to BIO's 6.5%. On growth, WAT holds the edge at +91.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…WAT logoWATWaters CorporationBIO logoBIOBio-Rad Laborator…
RevenueTrailing 12 months$45.2B$24.8B$7.1B$3.8B$2.6B
EBITDAEarnings before interest/tax$10.5B$7.2B$1.7B$953M-$315M
Net IncomeAfter-tax profit$6.9B$3.7B$1.3B$449M$169M
Free Cash FlowCash after capex$6.7B$5.3B$993M$264M$357M
Gross MarginGross profit ÷ Revenue+39.4%+60.7%+38.8%+55.0%+51.9%
Operating MarginEBIT ÷ Revenue+17.8%+21.0%+20.6%+17.1%+9.2%
Net MarginNet income ÷ Revenue+15.2%+14.9%+18.3%+11.9%+6.5%
FCF MarginFCF ÷ Revenue+14.9%+21.4%+14.1%+7.0%+13.8%
Rev. Growth (YoY)Latest quarter vs prior year+6.2%+3.7%+7.0%+91.5%+1.1%
EPS Growth (YoY)Latest quarter vs prior year+11.3%+9.8%-3.6%-142.9%-9.5%
DHR leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

BIO leads this category, winning 5 of 7 comparable metrics.

At 9.2x trailing earnings, BIO trades at a 73% valuation discount to DHR's 34.6x P/E. Adjusting for growth (PEG ratio), A offers better value at 1.75x vs DHR's 34.15x — a lower PEG means you pay less per unit of expected earnings growth.

MetricTMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…WAT logoWATWaters CorporationBIO logoBIOBio-Rad Laborator…
Market CapShares × price$173.5B$123.6B$33.3B$20.4B$6.9B
Enterprise ValueMkt cap + debt − cash$204.5B$137.4B$34.8B$21.2B$7.9B
Trailing P/EPrice ÷ TTM EPS26.31x34.65x25.72x31.83x9.23x
Forward P/EPrice ÷ next-FY EPS est.18.79x20.70x19.68x23.82x24.98x
PEG RatioP/E ÷ EPS growth rate12.46x34.15x1.75x6.15x
EV / EBITDAEnterprise value multiple18.78x18.12x19.71x19.29x16.69x
Price / SalesMarket cap ÷ Revenue3.89x5.03x4.79x6.44x2.69x
Price / BookPrice ÷ Book value/share3.29x2.36x4.95x7.98x0.94x
Price / FCFMarket cap ÷ FCF27.56x23.50x28.88x37.76x18.53x
BIO leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

WAT leads this category, winning 4 of 9 comparable metrics.

A delivers a 18.7% return on equity — every $100 of shareholder capital generates $19 in annual profit, vs $2 for BIO. BIO carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to TMO's 0.76x. On the Piotroski fundamental quality scale (0–9), DHR scores 7/9 vs WAT's 4/9, reflecting strong financial health.

MetricTMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…WAT logoWATWaters CorporationBIO logoBIOBio-Rad Laborator…
ROE (TTM)Return on equity+13.2%+7.1%+18.7%+8.0%+2.4%
ROA (TTM)Return on assets+6.4%+4.5%+10.1%+4.6%+2.2%
ROICReturn on invested capital+7.5%+5.9%+13.5%+20.3%+2.6%
ROCEReturn on capital employed+9.1%+7.0%+14.5%+18.5%+2.9%
Piotroski ScoreFundamental quality 0–967545
Debt / EquityFinancial leverage0.76x0.35x0.50x0.55x0.21x
Net DebtTotal debt minus cash$31.0B$13.8B$1.6B$820M$999M
Cash & Equiv.Liquid assets$9.9B$4.6B$1.8B$588M$532M
Total DebtShort + long-term debt$40.9B$18.4B$3.4B$1.4B$1.5B
Interest CoverageEBIT ÷ Interest expense5.89x18.13x19.53x6.72x-2.49x
WAT leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

WAT leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in WAT five years ago would be worth $11,104 today (with dividends reinvested), compared to $4,276 for BIO. Over the past 12 months, TMO leads with a +11.0% total return vs DHR's -10.8%. The 3-year compound annual growth rate (CAGR) favors WAT at 4.9% vs BIO's -12.6% — a key indicator of consistent wealth creation.

MetricTMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…WAT logoWATWaters CorporationBIO logoBIOBio-Rad Laborator…
YTD ReturnYear-to-date-21.1%-24.0%-14.4%-10.3%-15.8%
1-Year ReturnPast 12 months+11.0%-10.8%+9.4%-1.7%+7.0%
3-Year ReturnCumulative with dividends-13.7%-17.1%-9.7%+15.4%-33.3%
5-Year ReturnCumulative with dividends+1.3%-20.3%-8.4%+11.0%-57.2%
10-Year ReturnCumulative with dividends+229.0%+220.9%+205.7%+161.3%+79.3%
CAGR (3Y)Annualised 3-year return-4.8%-6.1%-3.3%+4.9%-12.6%
WAT leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — WAT and BIO each lead in 1 of 2 comparable metrics.

BIO is the less volatile stock with a 0.92 beta — it tends to amplify market swings less than A's 1.23 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. WAT currently trades 82.7% from its 52-week high vs DHR's 71.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…WAT logoWATWaters CorporationBIO logoBIOBio-Rad Laborator…
Beta (5Y)Sensitivity to S&P 5001.10x0.94x1.23x1.07x0.92x
52-Week HighHighest price in past year$643.99$242.80$160.27$414.15$343.12
52-Week LowLowest price in past year$385.46$172.34$104.36$275.05$211.43
% of 52W HighCurrent price vs 52-week peak+72.5%+71.9%+73.3%+82.7%+74.9%
RSI (14)Momentum oscillator 0–10037.631.241.943.835.7
Avg Volume (50D)Average daily shares traded1.8M4.1M2.0M981K302K
Evenly matched — WAT and BIO each lead in 1 of 2 comparable metrics.

Analyst Outlook

A leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: TMO as "Buy", DHR as "Buy", A as "Buy", WAT as "Hold", BIO as "Buy". Consensus price targets imply 41.4% upside for DHR (target: $247) vs 17.5% for WAT (target: $403). For income investors, A offers the higher dividend yield at 0.84% vs TMO's 0.36%.

MetricTMO logoTMOThermo Fisher Sci…DHR logoDHRDanaher Corporati…A logoAAgilent Technolog…WAT logoWATWaters CorporationBIO logoBIOBio-Rad Laborator…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHoldBuy
Price TargetConsensus 12-month target$654.67$247.00$166.00$402.57$312.50
# AnalystsCovering analysts4242383414
Dividend YieldAnnual dividend ÷ price+0.4%+0.7%+0.8%
Dividend StreakConsecutive years of raises81101
Dividend / ShareAnnual DPS$1.69$1.23$0.99
Buyback YieldShare repurchases ÷ mkt cap+1.7%+2.5%+1.3%+0.1%+4.3%
A leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

WAT leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). DHR leads in 1 (Income & Cash Flow). 1 tied.

Best OverallWaters Corporation (WAT)Leads 2 of 6 categories
Loading custom metrics...

TMO vs DHR vs A vs WAT vs BIO: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is TMO or DHR or A or WAT or BIO a better buy right now?

For growth investors, Waters Corporation (WAT) is the stronger pick with 7.

0% revenue growth year-over-year, versus 0. 7% for Bio-Rad Laboratories, Inc. (BIO). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 2x trailing P/E (25. 0x forward), making it the more compelling value choice. Analysts rate Thermo Fisher Scientific Inc. (TMO) a "Buy" — based on 42 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — TMO or DHR or A or WAT or BIO?

On trailing P/E, Bio-Rad Laboratories, Inc.

(BIO) is the cheapest at 9. 2x versus Danaher Corporation at 34. 6x. On forward P/E, Thermo Fisher Scientific Inc. is actually cheaper at 18. 8x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Agilent Technologies, Inc. wins at 1. 34x versus Danaher Corporation's 34. 15x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — TMO or DHR or A or WAT or BIO?

Over the past 5 years, Waters Corporation (WAT) delivered a total return of +11.

0%, compared to -57. 2% for Bio-Rad Laboratories, Inc. (BIO). Over 10 years, the gap is even starker: TMO returned +229. 0% versus BIO's +79. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — TMO or DHR or A or WAT or BIO?

By beta (market sensitivity over 5 years), Bio-Rad Laboratories, Inc.

(BIO) is the lower-risk stock at 0. 92β versus Agilent Technologies, Inc. 's 1. 23β — meaning A is approximately 33% more volatile than BIO relative to the S&P 500. On balance sheet safety, Bio-Rad Laboratories, Inc. (BIO) carries a lower debt/equity ratio of 21% versus 76% for Thermo Fisher Scientific Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — TMO or DHR or A or WAT or BIO?

By revenue growth (latest reported year), Waters Corporation (WAT) is pulling ahead at 7.

0% versus 0. 7% for Bio-Rad Laboratories, Inc. (BIO). On earnings-per-share growth, the picture is similar: Bio-Rad Laboratories, Inc. grew EPS 142. 6% year-over-year, compared to -4. 7% for Danaher Corporation. Over a 3-year CAGR, WAT leads at 2. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — TMO or DHR or A or WAT or BIO?

Bio-Rad Laboratories, Inc.

(BIO) is the more profitable company, earning 29. 4% net margin versus 14. 7% for Danaher Corporation — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: WAT leads at 28. 2% versus 10. 5% for BIO. At the gross margin level — before operating expenses — DHR leads at 60. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is TMO or DHR or A or WAT or BIO more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Agilent Technologies, Inc. (A) is the more undervalued stock at a PEG of 1. 34x versus Danaher Corporation's 34. 15x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Thermo Fisher Scientific Inc. (TMO) trades at 18. 8x forward P/E versus 25. 0x for Bio-Rad Laboratories, Inc. — 6. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DHR: 41. 4% to $247. 00.

08

Which pays a better dividend — TMO or DHR or A or WAT or BIO?

In this comparison, A (0.

8% yield), DHR (0. 7% yield), TMO (0. 4% yield) pay a dividend. WAT, BIO do not pay a meaningful dividend and should not be held primarily for income.

09

Is TMO or DHR or A or WAT or BIO better for a retirement portfolio?

For long-horizon retirement investors, Danaher Corporation (DHR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

94), 0. 7% yield, +220. 9% 10Y return). Both have compounded well over 10 years (DHR: +220. 9%, WAT: +161. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between TMO and DHR and A and WAT and BIO?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: TMO is a mid-cap quality compounder stock; DHR is a mid-cap quality compounder stock; A is a mid-cap quality compounder stock; WAT is a mid-cap quality compounder stock; BIO is a small-cap deep-value stock. DHR, A pay a dividend while TMO, WAT, BIO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Beat Both

Find stocks that outperform TMO and DHR and A and WAT and BIO on the metrics below

Revenue Growth>
%
(TMO: 6.2% · DHR: 3.7%)
Net Margin>
%
(TMO: 15.2% · DHR: 14.9%)
P/E Ratio<
x
(TMO: 26.3x · DHR: 34.6x)

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