Medical - Diagnostics & Research
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TMO vs DHR vs A vs WAT vs BIO
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Diagnostics & Research
Medical - Diagnostics & Research
Medical - Diagnostics & Research
Medical - Devices
TMO vs DHR vs A vs WAT vs BIO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Diagnostics & Research | Medical - Diagnostics & Research | Medical - Diagnostics & Research | Medical - Diagnostics & Research | Medical - Devices |
| Market Cap | $173.46B | $123.60B | $33.27B | $20.38B | $6.94B |
| Revenue (TTM) | $45.20B | $24.78B | $7.07B | $3.77B | $2.59B |
| Net Income (TTM) | $6.86B | $3.69B | $1.29B | $449M | $169M |
| Gross Margin | 39.4% | 60.7% | 38.8% | 55.0% | 51.9% |
| Operating Margin | 17.8% | 21.0% | 20.6% | 17.1% | 9.2% |
| Forward P/E | 18.8x | 20.7x | 19.7x | 23.8x | 25.0x |
| Total Debt | $40.85B | $18.42B | $3.35B | $1.41B | $1.53B |
| Cash & Equiv. | $9.86B | $4.62B | $1.79B | $588M | $532M |
TMO vs DHR vs A vs WAT vs BIO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Thermo Fisher Scien… (TMO) | 100 | 133.7 | +33.7% |
| Danaher Corporation (DHR) | 100 | 118.2 | +18.2% |
| Agilent Technologie… (A) | 100 | 133.3 | +33.3% |
| Waters Corporation (WAT) | 100 | 171.4 | +71.4% |
| Bio-Rad Laboratorie… (BIO) | 100 | 52.3 | -47.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TMO vs DHR vs A vs WAT vs BIO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TMO is the #2 pick in this set and the best alternative if long-term compounding is your priority.
- 229.0% 10Y total return vs DHR's 220.9%
- Lower P/E (18.8x vs 23.8x)
- +11.0% vs DHR's -10.8%
Among these 5 stocks, DHR doesn't own a clear edge in any measured category.
A carries the broadest edge in this set and is the clearest fit for income & stability and valuation efficiency.
- Dividend streak 10 yrs, beta 1.23, yield 0.8%
- PEG 1.34 vs DHR's 34.15
- 18.3% margin vs BIO's 6.5%
- 0.8% yield, 10-year raise streak, vs TMO's 0.4%, (2 stocks pay no dividend)
WAT ranks third and is worth considering specifically for growth exposure.
- Rev growth 7.0%, EPS growth 0.5%, 3Y rev CAGR 2.1%
- 7.0% revenue growth vs BIO's 0.7%
BIO is the clearest fit if your priority is sleep-well-at-night and defensive.
- Lower volatility, beta 0.92, Low D/E 20.5%, current ratio 5.62x
- Beta 0.92, current ratio 5.62x
- Beta 0.92 vs A's 1.23, lower leverage
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 7.0% revenue growth vs BIO's 0.7% | |
| Value | Lower P/E (18.8x vs 23.8x) | |
| Quality / Margins | 18.3% margin vs BIO's 6.5% | |
| Stability / Safety | Beta 0.92 vs A's 1.23, lower leverage | |
| Dividends | 0.8% yield, 10-year raise streak, vs TMO's 0.4%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +11.0% vs DHR's -10.8% | |
| Efficiency (ROA) | 10.1% ROA vs BIO's 2.2%, ROIC 13.5% vs 2.6% |
TMO vs DHR vs A vs WAT vs BIO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
TMO vs DHR vs A vs WAT vs BIO — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
WAT leads in 2 of 6 categories
DHR leads 1 • BIO leads 1 • A leads 1 • TMO leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
DHR leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
TMO is the larger business by revenue, generating $45.2B annually — 17.5x BIO's $2.6B. A is the more profitable business, keeping 18.3% of every revenue dollar as net income compared to BIO's 6.5%. On growth, WAT holds the edge at +91.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $45.2B | $24.8B | $7.1B | $3.8B | $2.6B |
| EBITDAEarnings before interest/tax | $10.5B | $7.2B | $1.7B | $953M | -$315M |
| Net IncomeAfter-tax profit | $6.9B | $3.7B | $1.3B | $449M | $169M |
| Free Cash FlowCash after capex | $6.7B | $5.3B | $993M | $264M | $357M |
| Gross MarginGross profit ÷ Revenue | +39.4% | +60.7% | +38.8% | +55.0% | +51.9% |
| Operating MarginEBIT ÷ Revenue | +17.8% | +21.0% | +20.6% | +17.1% | +9.2% |
| Net MarginNet income ÷ Revenue | +15.2% | +14.9% | +18.3% | +11.9% | +6.5% |
| FCF MarginFCF ÷ Revenue | +14.9% | +21.4% | +14.1% | +7.0% | +13.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | +6.2% | +3.7% | +7.0% | +91.5% | +1.1% |
| EPS Growth (YoY)Latest quarter vs prior year | +11.3% | +9.8% | -3.6% | -142.9% | -9.5% |
Valuation Metrics
BIO leads this category, winning 5 of 7 comparable metrics.
Valuation Metrics
At 9.2x trailing earnings, BIO trades at a 73% valuation discount to DHR's 34.6x P/E. Adjusting for growth (PEG ratio), A offers better value at 1.75x vs DHR's 34.15x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $173.5B | $123.6B | $33.3B | $20.4B | $6.9B |
| Enterprise ValueMkt cap + debt − cash | $204.5B | $137.4B | $34.8B | $21.2B | $7.9B |
| Trailing P/EPrice ÷ TTM EPS | 26.31x | 34.65x | 25.72x | 31.83x | 9.23x |
| Forward P/EPrice ÷ next-FY EPS est. | 18.79x | 20.70x | 19.68x | 23.82x | 24.98x |
| PEG RatioP/E ÷ EPS growth rate | 12.46x | 34.15x | 1.75x | 6.15x | — |
| EV / EBITDAEnterprise value multiple | 18.78x | 18.12x | 19.71x | 19.29x | 16.69x |
| Price / SalesMarket cap ÷ Revenue | 3.89x | 5.03x | 4.79x | 6.44x | 2.69x |
| Price / BookPrice ÷ Book value/share | 3.29x | 2.36x | 4.95x | 7.98x | 0.94x |
| Price / FCFMarket cap ÷ FCF | 27.56x | 23.50x | 28.88x | 37.76x | 18.53x |
Profitability & Efficiency
WAT leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
A delivers a 18.7% return on equity — every $100 of shareholder capital generates $19 in annual profit, vs $2 for BIO. BIO carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to TMO's 0.76x. On the Piotroski fundamental quality scale (0–9), DHR scores 7/9 vs WAT's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +13.2% | +7.1% | +18.7% | +8.0% | +2.4% |
| ROA (TTM)Return on assets | +6.4% | +4.5% | +10.1% | +4.6% | +2.2% |
| ROICReturn on invested capital | +7.5% | +5.9% | +13.5% | +20.3% | +2.6% |
| ROCEReturn on capital employed | +9.1% | +7.0% | +14.5% | +18.5% | +2.9% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 7 | 5 | 4 | 5 |
| Debt / EquityFinancial leverage | 0.76x | 0.35x | 0.50x | 0.55x | 0.21x |
| Net DebtTotal debt minus cash | $31.0B | $13.8B | $1.6B | $820M | $999M |
| Cash & Equiv.Liquid assets | $9.9B | $4.6B | $1.8B | $588M | $532M |
| Total DebtShort + long-term debt | $40.9B | $18.4B | $3.4B | $1.4B | $1.5B |
| Interest CoverageEBIT ÷ Interest expense | 5.89x | 18.13x | 19.53x | 6.72x | -2.49x |
Total Returns (Dividends Reinvested)
WAT leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in WAT five years ago would be worth $11,104 today (with dividends reinvested), compared to $4,276 for BIO. Over the past 12 months, TMO leads with a +11.0% total return vs DHR's -10.8%. The 3-year compound annual growth rate (CAGR) favors WAT at 4.9% vs BIO's -12.6% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -21.1% | -24.0% | -14.4% | -10.3% | -15.8% |
| 1-Year ReturnPast 12 months | +11.0% | -10.8% | +9.4% | -1.7% | +7.0% |
| 3-Year ReturnCumulative with dividends | -13.7% | -17.1% | -9.7% | +15.4% | -33.3% |
| 5-Year ReturnCumulative with dividends | +1.3% | -20.3% | -8.4% | +11.0% | -57.2% |
| 10-Year ReturnCumulative with dividends | +229.0% | +220.9% | +205.7% | +161.3% | +79.3% |
| CAGR (3Y)Annualised 3-year return | -4.8% | -6.1% | -3.3% | +4.9% | -12.6% |
Risk & Volatility
Evenly matched — WAT and BIO each lead in 1 of 2 comparable metrics.
Risk & Volatility
BIO is the less volatile stock with a 0.92 beta — it tends to amplify market swings less than A's 1.23 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. WAT currently trades 82.7% from its 52-week high vs DHR's 71.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.10x | 0.94x | 1.23x | 1.07x | 0.92x |
| 52-Week HighHighest price in past year | $643.99 | $242.80 | $160.27 | $414.15 | $343.12 |
| 52-Week LowLowest price in past year | $385.46 | $172.34 | $104.36 | $275.05 | $211.43 |
| % of 52W HighCurrent price vs 52-week peak | +72.5% | +71.9% | +73.3% | +82.7% | +74.9% |
| RSI (14)Momentum oscillator 0–100 | 37.6 | 31.2 | 41.9 | 43.8 | 35.7 |
| Avg Volume (50D)Average daily shares traded | 1.8M | 4.1M | 2.0M | 981K | 302K |
Analyst Outlook
A leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: TMO as "Buy", DHR as "Buy", A as "Buy", WAT as "Hold", BIO as "Buy". Consensus price targets imply 41.4% upside for DHR (target: $247) vs 17.5% for WAT (target: $403). For income investors, A offers the higher dividend yield at 0.84% vs TMO's 0.36%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | $654.67 | $247.00 | $166.00 | $402.57 | $312.50 |
| # AnalystsCovering analysts | 42 | 42 | 38 | 34 | 14 |
| Dividend YieldAnnual dividend ÷ price | +0.4% | +0.7% | +0.8% | — | — |
| Dividend StreakConsecutive years of raises | 8 | 1 | 10 | 1 | — |
| Dividend / ShareAnnual DPS | $1.69 | $1.23 | $0.99 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +1.7% | +2.5% | +1.3% | +0.1% | +4.3% |
WAT leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). DHR leads in 1 (Income & Cash Flow). 1 tied.
TMO vs DHR vs A vs WAT vs BIO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is TMO or DHR or A or WAT or BIO a better buy right now?
For growth investors, Waters Corporation (WAT) is the stronger pick with 7.
0% revenue growth year-over-year, versus 0. 7% for Bio-Rad Laboratories, Inc. (BIO). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 2x trailing P/E (25. 0x forward), making it the more compelling value choice. Analysts rate Thermo Fisher Scientific Inc. (TMO) a "Buy" — based on 42 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — TMO or DHR or A or WAT or BIO?
On trailing P/E, Bio-Rad Laboratories, Inc.
(BIO) is the cheapest at 9. 2x versus Danaher Corporation at 34. 6x. On forward P/E, Thermo Fisher Scientific Inc. is actually cheaper at 18. 8x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Agilent Technologies, Inc. wins at 1. 34x versus Danaher Corporation's 34. 15x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — TMO or DHR or A or WAT or BIO?
Over the past 5 years, Waters Corporation (WAT) delivered a total return of +11.
0%, compared to -57. 2% for Bio-Rad Laboratories, Inc. (BIO). Over 10 years, the gap is even starker: TMO returned +229. 0% versus BIO's +79. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — TMO or DHR or A or WAT or BIO?
By beta (market sensitivity over 5 years), Bio-Rad Laboratories, Inc.
(BIO) is the lower-risk stock at 0. 92β versus Agilent Technologies, Inc. 's 1. 23β — meaning A is approximately 33% more volatile than BIO relative to the S&P 500. On balance sheet safety, Bio-Rad Laboratories, Inc. (BIO) carries a lower debt/equity ratio of 21% versus 76% for Thermo Fisher Scientific Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — TMO or DHR or A or WAT or BIO?
By revenue growth (latest reported year), Waters Corporation (WAT) is pulling ahead at 7.
0% versus 0. 7% for Bio-Rad Laboratories, Inc. (BIO). On earnings-per-share growth, the picture is similar: Bio-Rad Laboratories, Inc. grew EPS 142. 6% year-over-year, compared to -4. 7% for Danaher Corporation. Over a 3-year CAGR, WAT leads at 2. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — TMO or DHR or A or WAT or BIO?
Bio-Rad Laboratories, Inc.
(BIO) is the more profitable company, earning 29. 4% net margin versus 14. 7% for Danaher Corporation — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: WAT leads at 28. 2% versus 10. 5% for BIO. At the gross margin level — before operating expenses — DHR leads at 60. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is TMO or DHR or A or WAT or BIO more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Agilent Technologies, Inc. (A) is the more undervalued stock at a PEG of 1. 34x versus Danaher Corporation's 34. 15x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Thermo Fisher Scientific Inc. (TMO) trades at 18. 8x forward P/E versus 25. 0x for Bio-Rad Laboratories, Inc. — 6. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DHR: 41. 4% to $247. 00.
08Which pays a better dividend — TMO or DHR or A or WAT or BIO?
In this comparison, A (0.
8% yield), DHR (0. 7% yield), TMO (0. 4% yield) pay a dividend. WAT, BIO do not pay a meaningful dividend and should not be held primarily for income.
09Is TMO or DHR or A or WAT or BIO better for a retirement portfolio?
For long-horizon retirement investors, Danaher Corporation (DHR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
94), 0. 7% yield, +220. 9% 10Y return). Both have compounded well over 10 years (DHR: +220. 9%, WAT: +161. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between TMO and DHR and A and WAT and BIO?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: TMO is a mid-cap quality compounder stock; DHR is a mid-cap quality compounder stock; A is a mid-cap quality compounder stock; WAT is a mid-cap quality compounder stock; BIO is a small-cap deep-value stock. DHR, A pay a dividend while TMO, WAT, BIO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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