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TTRX vs ABBV vs REGN vs CRL vs IQV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TTRX
Turn Therapeutics Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$119M
5Y Perf.-10.7%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$367.80B
5Y Perf.+124.4%
REGN
Regeneron Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$75.16B
5Y Perf.+18.0%
CRL
Charles River Laboratories International, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$8.13B
5Y Perf.-6.1%
IQV
IQVIA Holdings Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$29.71B
5Y Perf.+17.1%

TTRX vs ABBV vs REGN vs CRL vs IQV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TTRX logoTTRX
ABBV logoABBV
REGN logoREGN
CRL logoCRL
IQV logoIQV
IndustryBiotechnologyDrug Manufacturers - GeneralBiotechnologyMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$119M$367.80B$75.16B$8.13B$29.71B
Revenue (TTM)$61.16B$14.92B$4.03B$16.63B
Net Income (TTM)$-3M$4.23B$4.42B$-185M$1.39B
Gross Margin70.2%84.5%31.9%26.1%
Operating Margin26.7%24.3%11.8%13.9%
Forward P/E14.6x15.6x15.2x13.7x
Total Debt$80K$69.07B$2.71B$3.07B$16.17B
Cash & Equiv.$5M$5.23B$3.12B$214M$1.98B

TTRX vs ABBV vs REGN vs CRL vs IQVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TTRX
ABBV
REGN
CRL
IQV
StockMay 20May 26Return
AbbVie Inc. (ABBV)100224.4+124.4%
Regeneron Pharmaceu… (REGN)100118.0+18.0%
Charles River Labor… (CRL)10093.9-6.1%
IQVIA Holdings Inc. (IQV)100117.1+17.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: TTRX vs ABBV vs REGN vs CRL vs IQV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABBV and REGN are tied at the top with 3 categories each (5-stock set) — the right choice depends on your priorities. Regeneron Pharmaceuticals, Inc. is the stronger pick specifically for profitability and margin quality and recent price momentum and sentiment. IQV also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
TTRX
Turn Therapeutics Inc.
The Healthcare Pick

TTRX lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
ABBV
AbbVie Inc.
The Income Pick

ABBV carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 13 yrs, beta 0.28, yield 3.2%
  • Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
  • 311.6% 10Y total return vs IQV's 168.0%
  • 8.6% revenue growth vs CRL's -0.9%
Best for: income & stability and growth exposure
REGN
Regeneron Pharmaceuticals, Inc.
The Defensive Pick

REGN is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.

  • Lower volatility, beta 0.77, Low D/E 8.7%, current ratio 4.13x
  • Beta 0.77, yield 0.5%, current ratio 4.13x
  • 29.6% margin vs CRL's -4.6%
  • +26.3% vs TTRX's -43.1%
Best for: sleep-well-at-night and defensive
CRL
Charles River Laboratories International, Inc.
The Healthcare Pick

Among these 5 stocks, CRL doesn't own a clear edge in any measured category.

Best for: healthcare exposure
IQV
IQVIA Holdings Inc.
The Value Pick

IQV ranks third and is worth considering specifically for valuation efficiency.

  • PEG 0.34 vs REGN's 2.47
  • Lower P/E (13.7x vs 15.2x)
Best for: valuation efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthABBV logoABBV8.6% revenue growth vs CRL's -0.9%
ValueIQV logoIQVLower P/E (13.7x vs 15.2x)
Quality / MarginsREGN logoREGN29.6% margin vs CRL's -4.6%
Stability / SafetyABBV logoABBVBeta 0.28 vs TTRX's 1.45
DividendsABBV logoABBV3.2% yield, 13-year raise streak, vs REGN's 0.5%, (3 stocks pay no dividend)
Momentum (1Y)REGN logoREGN+26.3% vs TTRX's -43.1%
Efficiency (ROA)REGN logoREGN11.1% ROA vs TTRX's -45.0%

TTRX vs ABBV vs REGN vs CRL vs IQV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TTRXTurn Therapeutics Inc.

Segment breakdown not available.

ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B
REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M
CRLCharles River Laboratories International, Inc.
FY 2025
Discovery and Safety Assessment
59.8%$2.4B
Research Models and Services
21.1%$846M
Manufacturing Support
19.1%$766M
IQVIQVIA Holdings Inc.
FY 2025
Research And Development Solutions
54.5%$8.9B
Technology And Analytics Solutions
40.6%$6.6B
Contract Sales And Medical Solutions
4.8%$788M

TTRX vs ABBV vs REGN vs CRL vs IQV — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLABBVLAGGINGCRL

Income & Cash Flow (Last 12 Months)

Evenly matched — ABBV and REGN each lead in 3 of 6 comparable metrics.

ABBV is the larger business by revenue, generating $61.2B annually — 15.2x CRL's $4.0B. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to CRL's -4.6%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTTRX logoTTRXTurn Therapeutics…ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
RevenueTrailing 12 months$61.2B$14.9B$4.0B$16.6B
EBITDAEarnings before interest/tax$24.5B$4.2B$824M$3.5B
Net IncomeAfter-tax profit$4.2B$4.4B-$185M$1.4B
Free Cash FlowCash after capex$18.7B$4.2B$391M$2.7B
Gross MarginGross profit ÷ Revenue+70.2%+84.5%+31.9%+26.1%
Operating MarginEBIT ÷ Revenue+26.7%+24.3%+11.8%+13.9%
Net MarginNet income ÷ Revenue+6.9%+29.6%-4.6%+8.3%
FCF MarginFCF ÷ Revenue+30.6%+27.9%+9.7%+16.1%
Rev. Growth (YoY)Latest quarter vs prior year+10.0%+19.0%+1.2%+8.4%
EPS Growth (YoY)Latest quarter vs prior year+57.4%-7.2%-160.0%+15.0%
Evenly matched — ABBV and REGN each lead in 3 of 6 comparable metrics.

Valuation Metrics

IQV leads this category, winning 4 of 7 comparable metrics.

At 17.4x trailing earnings, REGN trades at a 80% valuation discount to ABBV's 87.7x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.55x vs REGN's 2.76x — a lower PEG means you pay less per unit of expected earnings growth.

MetricTTRX logoTTRXTurn Therapeutics…ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
Market CapShares × price$119M$367.8B$75.2B$8.1B$29.7B
Enterprise ValueMkt cap + debt − cash$114M$431.6B$74.8B$11.0B$43.9B
Trailing P/EPrice ÷ TTM EPS-17.30x87.74x17.44x-57.97x22.33x
Forward P/EPrice ÷ next-FY EPS est.14.62x15.65x15.20x13.68x
PEG RatioP/E ÷ EPS growth rate2.76x0.55x
EV / EBITDAEnterprise value multiple15.29x18.14x12.05x12.80x
Price / SalesMarket cap ÷ Revenue6.01x5.24x2.02x1.82x
Price / BookPrice ÷ Book value/share11.67x2.51x2.60x4.58x
Price / FCFMarket cap ÷ FCF20.64x18.42x15.67x14.48x
IQV leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

ABBV leads this category, winning 4 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-142 for TTRX. TTRX carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), ABBV scores 6/9 vs TTRX's 3/9, reflecting solid financial health.

MetricTTRX logoTTRXTurn Therapeutics…ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
ROE (TTM)Return on equity-141.7%+62.1%+14.3%-5.7%+22.1%
ROA (TTM)Return on assets-45.0%+3.1%+11.1%-2.5%+4.7%
ROICReturn on invested capital+23.9%+8.9%+6.3%+8.7%
ROCEReturn on capital employed-156.2%+21.5%+10.2%+8.1%+11.0%
Piotroski ScoreFundamental quality 0–936544
Debt / EquityFinancial leverage0.02x0.09x0.95x2.44x
Net DebtTotal debt minus cash-$5M$63.8B-$412M$2.9B$14.2B
Cash & Equiv.Liquid assets$5M$5.2B$3.1B$214M$2.0B
Total DebtShort + long-term debt$80,376$69.1B$2.7B$3.1B$16.2B
Interest CoverageEBIT ÷ Interest expense3.28x108.44x4.29x3.10x
ABBV leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ABBV leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ABBV five years ago would be worth $20,731 today (with dividends reinvested), compared to $5,325 for CRL. Over the past 12 months, REGN leads with a +26.3% total return vs TTRX's -43.1%. The 3-year compound annual growth rate (CAGR) favors ABBV at 15.6% vs TTRX's -17.2% — a key indicator of consistent wealth creation.

MetricTTRX logoTTRXTurn Therapeutics…ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
YTD ReturnYear-to-date-15.1%-7.8%-6.7%-16.7%-22.3%
1-Year ReturnPast 12 months-43.1%+12.9%+26.3%+17.9%+12.1%
3-Year ReturnCumulative with dividends-43.1%+54.3%-2.2%-11.8%-7.0%
5-Year ReturnCumulative with dividends-43.1%+107.3%+43.5%-46.7%-23.2%
10-Year ReturnCumulative with dividends-43.1%+311.6%+99.1%+107.2%+168.0%
CAGR (3Y)Annualised 3-year return-17.2%+15.6%-0.7%-4.1%-2.4%
ABBV leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ABBV and REGN each lead in 1 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.28 beta — it tends to amplify market swings less than TTRX's 1.45 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. REGN currently trades 88.1% from its 52-week high vs TTRX's 15.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTTRX logoTTRXTurn Therapeutics…ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
Beta (5Y)Sensitivity to S&P 5001.45x0.28x0.77x1.44x1.32x
52-Week HighHighest price in past year$26.50$244.81$821.11$228.88$247.05
52-Week LowLowest price in past year$2.57$176.57$476.49$132.58$134.65
% of 52W HighCurrent price vs 52-week peak+15.0%+84.9%+88.1%+73.7%+70.9%
RSI (14)Momentum oscillator 0–10064.144.643.145.353.8
Avg Volume (50D)Average daily shares traded22K5.7M631K780K1.5M
Evenly matched — ABBV and REGN each lead in 1 of 2 comparable metrics.

Analyst Outlook

ABBV leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: TTRX as "Buy", ABBV as "Buy", REGN as "Buy", CRL as "Buy", IQV as "Buy". Consensus price targets imply 27.8% upside for IQV (target: $224) vs 19.7% for REGN (target: $866). For income investors, ABBV offers the higher dividend yield at 3.16% vs REGN's 0.47%.

MetricTTRX logoTTRXTurn Therapeutics…ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$256.69$865.68$206.43$223.75
# AnalystsCovering analysts141483644
Dividend YieldAnnual dividend ÷ price+3.2%+0.5%
Dividend StreakConsecutive years of raises13112
Dividend / ShareAnnual DPS$6.57$3.41
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.3%+5.3%+4.4%+4.2%
ABBV leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

ABBV leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). IQV leads in 1 (Valuation Metrics). 2 tied.

Best OverallAbbVie Inc. (ABBV)Leads 3 of 6 categories
Loading custom metrics...

TTRX vs ABBV vs REGN vs CRL vs IQV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is TTRX or ABBV or REGN or CRL or IQV a better buy right now?

For growth investors, AbbVie Inc.

(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -0. 9% for Charles River Laboratories International, Inc. (CRL). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 4x trailing P/E (15. 6x forward), making it the more compelling value choice. Analysts rate Turn Therapeutics Inc. (TTRX) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — TTRX or ABBV or REGN or CRL or IQV?

On trailing P/E, Regeneron Pharmaceuticals, Inc.

(REGN) is the cheapest at 17. 4x versus AbbVie Inc. at 87. 7x. On forward P/E, IQVIA Holdings Inc. is actually cheaper at 13. 7x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 34x versus Regeneron Pharmaceuticals, Inc. 's 2. 47x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — TTRX or ABBV or REGN or CRL or IQV?

Over the past 5 years, AbbVie Inc.

(ABBV) delivered a total return of +107. 3%, compared to -46. 7% for Charles River Laboratories International, Inc. (CRL). Over 10 years, the gap is even starker: ABBV returned +311. 6% versus TTRX's -43. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — TTRX or ABBV or REGN or CRL or IQV?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 28β versus Turn Therapeutics Inc. 's 1. 45β — meaning TTRX is approximately 426% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Turn Therapeutics Inc. (TTRX) carries a lower debt/equity ratio of 2% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — TTRX or ABBV or REGN or CRL or IQV?

By revenue growth (latest reported year), AbbVie Inc.

(ABBV) is pulling ahead at 8. 6% versus -0. 9% for Charles River Laboratories International, Inc. (CRL). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — TTRX or ABBV or REGN or CRL or IQV?

Regeneron Pharmaceuticals, Inc.

(REGN) is the more profitable company, earning 31. 4% net margin versus -3. 6% for Charles River Laboratories International, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus 0. 0% for TTRX. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is TTRX or ABBV or REGN or CRL or IQV more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 34x versus Regeneron Pharmaceuticals, Inc. 's 2. 47x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, IQVIA Holdings Inc. (IQV) trades at 13. 7x forward P/E versus 15. 6x for Regeneron Pharmaceuticals, Inc. — 2. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for IQV: 27. 8% to $223. 75.

08

Which pays a better dividend — TTRX or ABBV or REGN or CRL or IQV?

In this comparison, ABBV (3.

2% yield), REGN (0. 5% yield) pay a dividend. TTRX, CRL, IQV do not pay a meaningful dividend and should not be held primarily for income.

09

Is TTRX or ABBV or REGN or CRL or IQV better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 28), 3. 2% yield, +311. 6% 10Y return). Both have compounded well over 10 years (ABBV: +311. 6%, TTRX: -43. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between TTRX and ABBV and REGN and CRL and IQV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: TTRX is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock; REGN is a mid-cap deep-value stock; CRL is a small-cap quality compounder stock; IQV is a mid-cap quality compounder stock. ABBV pays a dividend while TTRX, REGN, CRL, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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