Biotechnology
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5 / 10Stock Comparison
TTRX vs ABBV vs REGN vs CRL vs IQV
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Biotechnology
Medical - Diagnostics & Research
Medical - Diagnostics & Research
TTRX vs ABBV vs REGN vs CRL vs IQV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Biotechnology | Medical - Diagnostics & Research | Medical - Diagnostics & Research |
| Market Cap | $119M | $367.80B | $75.16B | $8.13B | $29.71B |
| Revenue (TTM) | — | $61.16B | $14.92B | $4.03B | $16.63B |
| Net Income (TTM) | $-3M | $4.23B | $4.42B | $-185M | $1.39B |
| Gross Margin | — | 70.2% | 84.5% | 31.9% | 26.1% |
| Operating Margin | — | 26.7% | 24.3% | 11.8% | 13.9% |
| Forward P/E | — | 14.6x | 15.6x | 15.2x | 13.7x |
| Total Debt | $80K | $69.07B | $2.71B | $3.07B | $16.17B |
| Cash & Equiv. | $5M | $5.23B | $3.12B | $214M | $1.98B |
TTRX vs ABBV vs REGN vs CRL vs IQV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| AbbVie Inc. (ABBV) | 100 | 224.4 | +124.4% |
| Regeneron Pharmaceu… (REGN) | 100 | 118.0 | +18.0% |
| Charles River Labor… (CRL) | 100 | 93.9 | -6.1% |
| IQVIA Holdings Inc. (IQV) | 100 | 117.1 | +17.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TTRX vs ABBV vs REGN vs CRL vs IQV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TTRX lags the leaders in this set but could rank higher in a more targeted comparison.
ABBV carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 13 yrs, beta 0.28, yield 3.2%
- Rev growth 8.6%, EPS growth -0.8%, 3Y rev CAGR 1.8%
- 311.6% 10Y total return vs IQV's 168.0%
- 8.6% revenue growth vs CRL's -0.9%
REGN is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 0.77, Low D/E 8.7%, current ratio 4.13x
- Beta 0.77, yield 0.5%, current ratio 4.13x
- 29.6% margin vs CRL's -4.6%
- +26.3% vs TTRX's -43.1%
Among these 5 stocks, CRL doesn't own a clear edge in any measured category.
IQV ranks third and is worth considering specifically for valuation efficiency.
- PEG 0.34 vs REGN's 2.47
- Lower P/E (13.7x vs 15.2x)
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 8.6% revenue growth vs CRL's -0.9% | |
| Value | Lower P/E (13.7x vs 15.2x) | |
| Quality / Margins | 29.6% margin vs CRL's -4.6% | |
| Stability / Safety | Beta 0.28 vs TTRX's 1.45 | |
| Dividends | 3.2% yield, 13-year raise streak, vs REGN's 0.5%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +26.3% vs TTRX's -43.1% | |
| Efficiency (ROA) | 11.1% ROA vs TTRX's -45.0% |
TTRX vs ABBV vs REGN vs CRL vs IQV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
TTRX vs ABBV vs REGN vs CRL vs IQV — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ABBV leads in 3 of 6 categories
IQV leads 1 • TTRX leads 0 • REGN leads 0 • CRL leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — ABBV and REGN each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ABBV is the larger business by revenue, generating $61.2B annually — 15.2x CRL's $4.0B. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to CRL's -4.6%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | — | $61.2B | $14.9B | $4.0B | $16.6B |
| EBITDAEarnings before interest/tax | — | $24.5B | $4.2B | $824M | $3.5B |
| Net IncomeAfter-tax profit | — | $4.2B | $4.4B | -$185M | $1.4B |
| Free Cash FlowCash after capex | — | $18.7B | $4.2B | $391M | $2.7B |
| Gross MarginGross profit ÷ Revenue | — | +70.2% | +84.5% | +31.9% | +26.1% |
| Operating MarginEBIT ÷ Revenue | — | +26.7% | +24.3% | +11.8% | +13.9% |
| Net MarginNet income ÷ Revenue | — | +6.9% | +29.6% | -4.6% | +8.3% |
| FCF MarginFCF ÷ Revenue | — | +30.6% | +27.9% | +9.7% | +16.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +10.0% | +19.0% | +1.2% | +8.4% |
| EPS Growth (YoY)Latest quarter vs prior year | — | +57.4% | -7.2% | -160.0% | +15.0% |
Valuation Metrics
IQV leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 17.4x trailing earnings, REGN trades at a 80% valuation discount to ABBV's 87.7x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.55x vs REGN's 2.76x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $119M | $367.8B | $75.2B | $8.1B | $29.7B |
| Enterprise ValueMkt cap + debt − cash | $114M | $431.6B | $74.8B | $11.0B | $43.9B |
| Trailing P/EPrice ÷ TTM EPS | -17.30x | 87.74x | 17.44x | -57.97x | 22.33x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 14.62x | 15.65x | 15.20x | 13.68x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 2.76x | — | 0.55x |
| EV / EBITDAEnterprise value multiple | — | 15.29x | 18.14x | 12.05x | 12.80x |
| Price / SalesMarket cap ÷ Revenue | — | 6.01x | 5.24x | 2.02x | 1.82x |
| Price / BookPrice ÷ Book value/share | 11.67x | — | 2.51x | 2.60x | 4.58x |
| Price / FCFMarket cap ÷ FCF | — | 20.64x | 18.42x | 15.67x | 14.48x |
Profitability & Efficiency
ABBV leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-142 for TTRX. TTRX carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), ABBV scores 6/9 vs TTRX's 3/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -141.7% | +62.1% | +14.3% | -5.7% | +22.1% |
| ROA (TTM)Return on assets | -45.0% | +3.1% | +11.1% | -2.5% | +4.7% |
| ROICReturn on invested capital | — | +23.9% | +8.9% | +6.3% | +8.7% |
| ROCEReturn on capital employed | -156.2% | +21.5% | +10.2% | +8.1% | +11.0% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 6 | 5 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.02x | — | 0.09x | 0.95x | 2.44x |
| Net DebtTotal debt minus cash | -$5M | $63.8B | -$412M | $2.9B | $14.2B |
| Cash & Equiv.Liquid assets | $5M | $5.2B | $3.1B | $214M | $2.0B |
| Total DebtShort + long-term debt | $80,376 | $69.1B | $2.7B | $3.1B | $16.2B |
| Interest CoverageEBIT ÷ Interest expense | — | 3.28x | 108.44x | 4.29x | 3.10x |
Total Returns (Dividends Reinvested)
ABBV leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $20,731 today (with dividends reinvested), compared to $5,325 for CRL. Over the past 12 months, REGN leads with a +26.3% total return vs TTRX's -43.1%. The 3-year compound annual growth rate (CAGR) favors ABBV at 15.6% vs TTRX's -17.2% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -15.1% | -7.8% | -6.7% | -16.7% | -22.3% |
| 1-Year ReturnPast 12 months | -43.1% | +12.9% | +26.3% | +17.9% | +12.1% |
| 3-Year ReturnCumulative with dividends | -43.1% | +54.3% | -2.2% | -11.8% | -7.0% |
| 5-Year ReturnCumulative with dividends | -43.1% | +107.3% | +43.5% | -46.7% | -23.2% |
| 10-Year ReturnCumulative with dividends | -43.1% | +311.6% | +99.1% | +107.2% | +168.0% |
| CAGR (3Y)Annualised 3-year return | -17.2% | +15.6% | -0.7% | -4.1% | -2.4% |
Risk & Volatility
Evenly matched — ABBV and REGN each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.28 beta — it tends to amplify market swings less than TTRX's 1.45 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. REGN currently trades 88.1% from its 52-week high vs TTRX's 15.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.45x | 0.28x | 0.77x | 1.44x | 1.32x |
| 52-Week HighHighest price in past year | $26.50 | $244.81 | $821.11 | $228.88 | $247.05 |
| 52-Week LowLowest price in past year | $2.57 | $176.57 | $476.49 | $132.58 | $134.65 |
| % of 52W HighCurrent price vs 52-week peak | +15.0% | +84.9% | +88.1% | +73.7% | +70.9% |
| RSI (14)Momentum oscillator 0–100 | 64.1 | 44.6 | 43.1 | 45.3 | 53.8 |
| Avg Volume (50D)Average daily shares traded | 22K | 5.7M | 631K | 780K | 1.5M |
Analyst Outlook
ABBV leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: TTRX as "Buy", ABBV as "Buy", REGN as "Buy", CRL as "Buy", IQV as "Buy". Consensus price targets imply 27.8% upside for IQV (target: $224) vs 19.7% for REGN (target: $866). For income investors, ABBV offers the higher dividend yield at 3.16% vs REGN's 0.47%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $256.69 | $865.68 | $206.43 | $223.75 |
| # AnalystsCovering analysts | 1 | 41 | 48 | 36 | 44 |
| Dividend YieldAnnual dividend ÷ price | — | +3.2% | +0.5% | — | — |
| Dividend StreakConsecutive years of raises | — | 13 | 1 | 1 | 2 |
| Dividend / ShareAnnual DPS | — | $6.57 | $3.41 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.3% | +5.3% | +4.4% | +4.2% |
ABBV leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). IQV leads in 1 (Valuation Metrics). 2 tied.
TTRX vs ABBV vs REGN vs CRL vs IQV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is TTRX or ABBV or REGN or CRL or IQV a better buy right now?
For growth investors, AbbVie Inc.
(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -0. 9% for Charles River Laboratories International, Inc. (CRL). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 4x trailing P/E (15. 6x forward), making it the more compelling value choice. Analysts rate Turn Therapeutics Inc. (TTRX) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — TTRX or ABBV or REGN or CRL or IQV?
On trailing P/E, Regeneron Pharmaceuticals, Inc.
(REGN) is the cheapest at 17. 4x versus AbbVie Inc. at 87. 7x. On forward P/E, IQVIA Holdings Inc. is actually cheaper at 13. 7x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 34x versus Regeneron Pharmaceuticals, Inc. 's 2. 47x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — TTRX or ABBV or REGN or CRL or IQV?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +107. 3%, compared to -46. 7% for Charles River Laboratories International, Inc. (CRL). Over 10 years, the gap is even starker: ABBV returned +311. 6% versus TTRX's -43. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — TTRX or ABBV or REGN or CRL or IQV?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 28β versus Turn Therapeutics Inc. 's 1. 45β — meaning TTRX is approximately 426% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Turn Therapeutics Inc. (TTRX) carries a lower debt/equity ratio of 2% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — TTRX or ABBV or REGN or CRL or IQV?
By revenue growth (latest reported year), AbbVie Inc.
(ABBV) is pulling ahead at 8. 6% versus -0. 9% for Charles River Laboratories International, Inc. (CRL). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — TTRX or ABBV or REGN or CRL or IQV?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus -3. 6% for Charles River Laboratories International, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus 0. 0% for TTRX. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is TTRX or ABBV or REGN or CRL or IQV more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 34x versus Regeneron Pharmaceuticals, Inc. 's 2. 47x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, IQVIA Holdings Inc. (IQV) trades at 13. 7x forward P/E versus 15. 6x for Regeneron Pharmaceuticals, Inc. — 2. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for IQV: 27. 8% to $223. 75.
08Which pays a better dividend — TTRX or ABBV or REGN or CRL or IQV?
In this comparison, ABBV (3.
2% yield), REGN (0. 5% yield) pay a dividend. TTRX, CRL, IQV do not pay a meaningful dividend and should not be held primarily for income.
09Is TTRX or ABBV or REGN or CRL or IQV better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 28), 3. 2% yield, +311. 6% 10Y return). Both have compounded well over 10 years (ABBV: +311. 6%, TTRX: -43. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between TTRX and ABBV and REGN and CRL and IQV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: TTRX is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock; REGN is a mid-cap deep-value stock; CRL is a small-cap quality compounder stock; IQV is a mid-cap quality compounder stock. ABBV pays a dividend while TTRX, REGN, CRL, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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