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Stock Comparison

TTRX vs IMVT vs RCUS vs ARDX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
TTRX
Turn Therapeutics Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$119M
5Y Perf.-10.7%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.83B
5Y Perf.+11.7%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.51B
5Y Perf.-20.6%
ARDX
Ardelyx, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.62B
5Y Perf.+261.2%

TTRX vs IMVT vs RCUS vs ARDX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
TTRX logoTTRX
IMVT logoIMVT
RCUS logoRCUS
ARDX logoARDX
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$119M$5.83B$2.51B$1.62B
Revenue (TTM)$0.00$236M$428M
Net Income (TTM)$-3M$-464M$-369M$-58M
Gross Margin90.7%91.9%
Operating Margin-168.6%-8.7%
Total Debt$80K$98K$99M$212M
Cash & Equiv.$5M$714M$222M$68M

TTRX vs IMVT vs RCUS vs ARDXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

TTRX
IMVT
RCUS
ARDX
StockMay 20May 26Return
Immunovant, Inc. (IMVT)100111.7+11.7%
Arcus Biosciences, … (RCUS)10079.4-20.6%
Ardelyx, Inc. (ARDX)100361.2+261.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: TTRX vs IMVT vs RCUS vs ARDX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ARDX leads in 3 of 6 categories, making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. Immunovant, Inc. is the stronger pick specifically for profitability and margin quality. RCUS also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
TTRX
Turn Therapeutics Inc.
The Secondary Option

TTRX lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
IMVT
Immunovant, Inc.
The Defensive Pick

IMVT is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.

  • Lower volatility, beta 1.36, Low D/E 0.0%, current ratio 11.16x
  • Beta 1.36, current ratio 11.16x
  • 3.2% margin vs RCUS's -156.4%
Best for: sleep-well-at-night and defensive
RCUS
Arcus Biosciences, Inc.
The Momentum Pick

RCUS is the clearest fit if your priority is momentum.

  • +183.0% vs TTRX's -43.1%
Best for: momentum
ARDX
Ardelyx, Inc.
The Income Pick

ARDX carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 1.05
  • Rev growth 22.1%, EPS growth -52.9%, 3Y rev CAGR 98.4%
  • 308.0% 10Y total return vs IMVT's 187.9%
  • 22.1% revenue growth vs IMVT's -21.3%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthARDX logoARDX22.1% revenue growth vs IMVT's -21.3%
Quality / MarginsIMVT logoIMVT3.2% margin vs RCUS's -156.4%
Stability / SafetyARDX logoARDXBeta 1.05 vs RCUS's 1.84
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)RCUS logoRCUS+183.0% vs TTRX's -43.1%
Efficiency (ROA)ARDX logoARDX-11.8% ROA vs TTRX's -45.0%

TTRX vs IMVT vs RCUS vs ARDX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

TTRXTurn Therapeutics Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M
ARDXArdelyx, Inc.
FY 2025
Product
57.5%$378M
Product, IBSRELA
41.7%$274M
License
0.8%$5M

TTRX vs IMVT vs RCUS vs ARDX — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLARDXLAGGINGRCUS

Income & Cash Flow (Last 12 Months)

ARDX leads this category, winning 5 of 6 comparable metrics.

ARDX and IMVT operate at a comparable scale, with $428M and $0 in trailing revenue. ARDX is the more profitable business, keeping -13.6% of every revenue dollar as net income compared to RCUS's -156.4%. On growth, ARDX holds the edge at +27.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricTTRX logoTTRXTurn Therapeutics…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…ARDX logoARDXArdelyx, Inc.
RevenueTrailing 12 months$0$236M$428M
EBITDAEarnings before interest/tax-$487M-$391M-$35M
Net IncomeAfter-tax profit-$464M-$369M-$58M
Free Cash FlowCash after capex-$423M-$489M-$37M
Gross MarginGross profit ÷ Revenue+90.7%+91.9%
Operating MarginEBIT ÷ Revenue-168.6%-8.7%
Net MarginNet income ÷ Revenue-156.4%-13.6%
FCF MarginFCF ÷ Revenue-2.1%-8.8%
Rev. Growth (YoY)Latest quarter vs prior year-39.3%+27.5%
EPS Growth (YoY)Latest quarter vs prior year+19.7%+10.5%+11.8%
ARDX leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

ARDX leads this category, winning 2 of 3 comparable metrics.
MetricTTRX logoTTRXTurn Therapeutics…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…ARDX logoARDXArdelyx, Inc.
Market CapShares × price$119M$5.8B$2.5B$1.6B
Enterprise ValueMkt cap + debt − cash$114M$5.1B$2.4B$1.8B
Trailing P/EPrice ÷ TTM EPS-17.30x-10.49x-7.57x-25.42x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue10.15x3.98x
Price / BookPrice ÷ Book value/share11.67x6.14x4.24x9.54x
Price / FCFMarket cap ÷ FCF
ARDX leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

ARDX leads this category, winning 6 of 9 comparable metrics.

ARDX delivers a -38.1% return on equity — every $100 of shareholder capital generates $-38 in annual profit, vs $-142 for TTRX. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ARDX's 1.27x. On the Piotroski fundamental quality scale (0–9), TTRX scores 3/9 vs RCUS's 0/9, reflecting mixed financial health.

MetricTTRX logoTTRXTurn Therapeutics…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…ARDX logoARDXArdelyx, Inc.
ROE (TTM)Return on equity-141.7%-47.1%-69.0%-38.1%
ROA (TTM)Return on assets-45.0%-44.1%-35.3%-11.8%
ROICReturn on invested capital-64.1%-10.7%
ROCEReturn on capital employed-156.2%-66.1%-42.1%-10.6%
Piotroski ScoreFundamental quality 0–93203
Debt / EquityFinancial leverage0.02x0.00x0.16x1.27x
Net DebtTotal debt minus cash-$5M-$714M-$123M$144M
Cash & Equiv.Liquid assets$5M$714M$222M$68M
Total DebtShort + long-term debt$80,376$98,000$99M$212M
Interest CoverageEBIT ÷ Interest expense-13.38x-0.28x
ARDX leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

IMVT leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ARDX five years ago would be worth $39,345 today (with dividends reinvested), compared to $5,686 for TTRX. Over the past 12 months, RCUS leads with a +183.0% total return vs TTRX's -43.1%. The 3-year compound annual growth rate (CAGR) favors IMVT at 16.9% vs TTRX's -17.2% — a key indicator of consistent wealth creation.

MetricTTRX logoTTRXTurn Therapeutics…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…ARDX logoARDXArdelyx, Inc.
YTD ReturnYear-to-date-15.1%+10.6%+6.9%+7.5%
1-Year ReturnPast 12 months-43.1%+96.9%+183.0%+87.3%
3-Year ReturnCumulative with dividends-43.1%+59.6%+34.7%+54.1%
5-Year ReturnCumulative with dividends-43.1%+83.3%-14.6%+293.5%
10-Year ReturnCumulative with dividends-43.1%+187.9%+46.5%+308.0%
CAGR (3Y)Annualised 3-year return-17.2%+16.9%+10.4%+15.5%
IMVT leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — IMVT and ARDX each lead in 1 of 2 comparable metrics.

ARDX is the less volatile stock with a 1.05 beta — it tends to amplify market swings less than RCUS's 1.84 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 95.0% from its 52-week high vs TTRX's 15.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricTTRX logoTTRXTurn Therapeutics…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…ARDX logoARDXArdelyx, Inc.
Beta (5Y)Sensitivity to S&P 5001.45x1.36x1.84x1.05x
52-Week HighHighest price in past year$26.50$30.16$28.72$8.40
52-Week LowLowest price in past year$2.57$13.52$7.91$3.21
% of 52W HighCurrent price vs 52-week peak+15.0%+95.0%+86.7%+78.7%
RSI (14)Momentum oscillator 0–10064.159.552.754.4
Avg Volume (50D)Average daily shares traded22K1.4M1.1M3.6M
Evenly matched — IMVT and ARDX each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: TTRX as "Buy", IMVT as "Buy", RCUS as "Buy", ARDX as "Buy". Consensus price targets imply 157.2% upside for ARDX (target: $17) vs 20.5% for RCUS (target: $30).

MetricTTRX logoTTRXTurn Therapeutics…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…ARDX logoARDXArdelyx, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$45.50$30.00$17.00
# AnalystsCovering analysts1231816
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

ARDX leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). IMVT leads in 1 (Total Returns). 1 tied.

Best OverallArdelyx, Inc. (ARDX)Leads 3 of 6 categories
Loading custom metrics...

TTRX vs IMVT vs RCUS vs ARDX: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is TTRX or IMVT or RCUS or ARDX a better buy right now?

For growth investors, Ardelyx, Inc.

(ARDX) is the stronger pick with 22. 1% revenue growth year-over-year, versus -4. 3% for Arcus Biosciences, Inc. (RCUS). Analysts rate Turn Therapeutics Inc. (TTRX) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — TTRX or IMVT or RCUS or ARDX?

Over the past 5 years, Ardelyx, Inc.

(ARDX) delivered a total return of +293. 5%, compared to -43. 1% for Turn Therapeutics Inc. (TTRX). Over 10 years, the gap is even starker: ARDX returned +308. 0% versus TTRX's -43. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — TTRX or IMVT or RCUS or ARDX?

By beta (market sensitivity over 5 years), Ardelyx, Inc.

(ARDX) is the lower-risk stock at 1. 05β versus Arcus Biosciences, Inc. 's 1. 84β — meaning RCUS is approximately 74% more volatile than ARDX relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 127% for Ardelyx, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — TTRX or IMVT or RCUS or ARDX?

By revenue growth (latest reported year), Ardelyx, Inc.

(ARDX) is pulling ahead at 22. 1% versus -4. 3% for Arcus Biosciences, Inc. (RCUS). On earnings-per-share growth, the picture is similar: Arcus Biosciences, Inc. grew EPS -4. 8% year-over-year, compared to -76. 9% for Turn Therapeutics Inc.. Over a 3-year CAGR, ARDX leads at 98. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — TTRX or IMVT or RCUS or ARDX?

Turn Therapeutics Inc.

(TTRX) is the more profitable company, earning 0. 0% net margin versus -142. 9% for Arcus Biosciences, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: TTRX leads at 0. 0% versus -156. 3% for RCUS. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — TTRX or IMVT or RCUS or ARDX?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is TTRX or IMVT or RCUS or ARDX better for a retirement portfolio?

For long-horizon retirement investors, Ardelyx, Inc.

(ARDX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 05), +308. 0% 10Y return). Arcus Biosciences, Inc. (RCUS) carries a higher beta of 1. 84 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ARDX: +308. 0%, RCUS: +46. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between TTRX and IMVT and RCUS and ARDX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: TTRX is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; RCUS is a small-cap quality compounder stock; ARDX is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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