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Stock Comparison

VNRX vs DBVT vs EXAS vs ALKS vs GH

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
VNRX
VolitionRx Limited

Medical - Diagnostics & Research

HealthcareAMEX • US
Market Cap$12M
5Y Perf.-96.3%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1690.08T
5Y Perf.-59.3%
EXAS
Exact Sciences Corporation

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$20.02B
5Y Perf.+20.4%
ALKS
Alkermes plc

Biotechnology

HealthcareNASDAQ • IE
Market Cap$5.83B
5Y Perf.+113.9%
GH
Guardant Health, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$12.55B
5Y Perf.+5.9%

VNRX vs DBVT vs EXAS vs ALKS vs GH — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
VNRX logoVNRX
DBVT logoDBVT
EXAS logoEXAS
ALKS logoALKS
GH logoGH
IndustryMedical - Diagnostics & ResearchBiotechnologyMedical - Diagnostics & ResearchBiotechnologyMedical - Diagnostics & Research
Market Cap$12M$1690.08T$20.02B$5.83B$12.55B
Revenue (TTM)$2M$0.00$3.25B$1.56B$1.08B
Net Income (TTM)$-23M$-168M$-208M$153M$-433M
Gross Margin100.0%69.7%65.4%64.9%
Operating Margin-12.5%-6.4%12.3%-41.4%
Forward P/E582.8x24.5x
Total Debt$11M$22M$2.52B$70M$1.68B
Cash & Equiv.$1M$194M$956M$1.12B$378M

VNRX vs DBVT vs EXAS vs ALKS vs GHLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

VNRX
DBVT
EXAS
ALKS
GH
StockMay 20May 26Return
VolitionRx Limited (VNRX)1003.7-96.3%
DBV Technologies S.… (DBVT)10040.7-59.3%
Exact Sciences Corp… (EXAS)100120.4+20.4%
Alkermes plc (ALKS)100213.9+113.9%
Guardant Health, In… (GH)100105.9+5.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: VNRX vs DBVT vs EXAS vs ALKS vs GH

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ALKS leads in 3 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. VolitionRx Limited is the stronger pick specifically for growth and revenue expansion. EXAS and GH also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
VNRX
VolitionRx Limited
The Growth Play

VNRX is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 40.0%, EPS growth 29.0%, 3Y rev CAGR 78.0%
  • 40.0% revenue growth vs DBVT's -100.0%
Best for: growth exposure
DBVT
DBV Technologies S.A.
The Income Pick

DBVT is the clearest fit if your priority is income & stability.

  • Dividend streak 0 yrs, beta 1.26
Best for: income & stability
EXAS
Exact Sciences Corporation
The Long-Run Compounder

EXAS ranks third and is worth considering specifically for long-term compounding and sleep-well-at-night.

  • 16.7% 10Y total return vs ALKS's -12.0%
  • Lower volatility, beta 0.05, current ratio 2.43x
  • Beta 0.05 vs DBVT's 1.26
Best for: long-term compounding and sleep-well-at-night
ALKS
Alkermes plc
The Value Play

ALKS carries the broadest edge in this set and is the clearest fit for value and quality.

  • Better valuation composite
  • 9.8% margin vs VNRX's -13.5%
  • 5.4% ROA vs VNRX's -305.6%
Best for: value and quality
GH
Guardant Health, Inc.
The Defensive Pick

GH is the clearest fit if your priority is defensive.

  • Beta 0.86, current ratio 4.84x
  • +129.6% vs VNRX's -78.3%
Best for: defensive
See the full category breakdown
CategoryWinnerWhy
GrowthVNRX logoVNRX40.0% revenue growth vs DBVT's -100.0%
ValueALKS logoALKSBetter valuation composite
Quality / MarginsALKS logoALKS9.8% margin vs VNRX's -13.5%
Stability / SafetyEXAS logoEXASBeta 0.05 vs DBVT's 1.26
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)GH logoGH+129.6% vs VNRX's -78.3%
Efficiency (ROA)ALKS logoALKS5.4% ROA vs VNRX's -305.6%

VNRX vs DBVT vs EXAS vs ALKS vs GH — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

VNRXVolitionRx Limited

Segment breakdown not available.

DBVTDBV Technologies S.A.

Segment breakdown not available.

EXASExact Sciences Corporation
FY 2025
Screening
77.9%$2.5B
Precision Oncology
22.1%$717M
ALKSAlkermes plc
FY 2025
Vivitrol
39.8%$468M
Aristada And Aristada Initio
31.5%$370M
Manufactured Product And Royalty
24.8%$291M
Manufacturing Revenue
3.9%$46M
GHGuardant Health, Inc.
FY 2025
Oncology
69.6%$684M
Biopharma & Data
21.4%$210M
Screening
8.1%$80M
Licensing & Other
0.9%$9M

VNRX vs DBVT vs EXAS vs ALKS vs GH — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLALKSLAGGINGDBVT

Income & Cash Flow (Last 12 Months)

ALKS leads this category, winning 3 of 6 comparable metrics.

EXAS and DBVT operate at a comparable scale, with $3.2B and $0 in trailing revenue. ALKS is the more profitable business, keeping 9.8% of every revenue dollar as net income compared to VNRX's -13.5%. On growth, VNRX holds the edge at +133.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricVNRX logoVNRXVolitionRx LimitedDBVT logoDBVTDBV Technologies …EXAS logoEXASExact Sciences Co…ALKS logoALKSAlkermes plcGH logoGHGuardant Health, …
RevenueTrailing 12 months$2M$0$3.2B$1.6B$1.1B
EBITDAEarnings before interest/tax-$20M-$112M-$41M$212M-$418M
Net IncomeAfter-tax profit-$23M-$168M-$208M$153M-$433M
Free Cash FlowCash after capex-$20M-$151M$357M$392M-$225M
Gross MarginGross profit ÷ Revenue+100.0%+69.7%+65.4%+64.9%
Operating MarginEBIT ÷ Revenue-12.5%-6.4%+12.3%-41.4%
Net MarginNet income ÷ Revenue-13.5%-6.4%+9.8%-40.1%
FCF MarginFCF ÷ Revenue-11.4%+11.0%+25.1%-20.8%
Rev. Growth (YoY)Latest quarter vs prior year+133.2%+23.1%+28.2%+48.3%
EPS Growth (YoY)Latest quarter vs prior year+20.5%+91.5%+90.4%-4.1%-10.4%
ALKS leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

ALKS leads this category, winning 2 of 4 comparable metrics.
MetricVNRX logoVNRXVolitionRx LimitedDBVT logoDBVTDBV Technologies …EXAS logoEXASExact Sciences Co…ALKS logoALKSAlkermes plcGH logoGHGuardant Health, …
Market CapShares × price$12M$1690.08T$20.0B$5.8B$12.6B
Enterprise ValueMkt cap + debt − cash$22M$1690.08T$21.6B$4.8B$13.9B
Trailing P/EPrice ÷ TTM EPS-0.51x-0.75x-95.37x24.47x-28.83x
Forward P/EPrice ÷ next-FY EPS est.582.83x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple17.01x
Price / SalesMarket cap ÷ Revenue6.97x6.16x3.95x12.78x
Price / BookPrice ÷ Book value/share0.65x8.24x3.25x
Price / FCFMarket cap ÷ FCF56.10x12.14x
ALKS leads this category, winning 2 of 4 comparable metrics.

Profitability & Efficiency

ALKS leads this category, winning 8 of 9 comparable metrics.

ALKS delivers a 8.8% return on equity — every $100 of shareholder capital generates $9 in annual profit, vs $-130 for DBVT. ALKS carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to EXAS's 1.05x. On the Piotroski fundamental quality scale (0–9), EXAS scores 7/9 vs VNRX's 2/9, reflecting strong financial health.

MetricVNRX logoVNRXVolitionRx LimitedDBVT logoDBVTDBV Technologies …EXAS logoEXASExact Sciences Co…ALKS logoALKSAlkermes plcGH logoGHGuardant Health, …
ROE (TTM)Return on equity-130.2%-8.7%+8.8%
ROA (TTM)Return on assets-3.1%-89.0%-3.5%+5.4%-26.5%
ROICReturn on invested capital-3.6%+18.9%-34.9%
ROCEReturn on capital employed-145.7%-4.0%+14.2%-29.4%
Piotroski ScoreFundamental quality 0–924775
Debt / EquityFinancial leverage0.13x1.05x0.04x
Net DebtTotal debt minus cash$10M-$172M$1.6B-$1.0B$1.3B
Cash & Equiv.Liquid assets$1M$194M$956M$1.1B$378M
Total DebtShort + long-term debt$11M$22M$2.5B$70M$1.7B
Interest CoverageEBIT ÷ Interest expense-8.44x-189.82x-5.47x32.30x-250.66x
ALKS leads this category, winning 8 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GH leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ALKS five years ago would be worth $16,165 today (with dividends reinvested), compared to $371 for VNRX. Over the past 12 months, GH leads with a +129.6% total return vs VNRX's -78.3%. The 3-year compound annual growth rate (CAGR) favors GH at 59.6% vs VNRX's -61.7% — a key indicator of consistent wealth creation.

MetricVNRX logoVNRXVolitionRx LimitedDBVT logoDBVTDBV Technologies …EXAS logoEXASExact Sciences Co…ALKS logoALKSAlkermes plcGH logoGHGuardant Health, …
YTD ReturnYear-to-date-58.8%+3.6%+3.1%+23.8%-5.9%
1-Year ReturnPast 12 months-78.3%+100.5%+97.7%+15.2%+129.6%
3-Year ReturnCumulative with dividends-94.4%+18.1%+53.0%+13.2%+306.7%
5-Year ReturnCumulative with dividends-96.3%-68.3%+6.1%+61.7%-21.4%
10-Year ReturnCumulative with dividends-96.5%-87.1%+1669.1%-12.0%+197.2%
CAGR (3Y)Annualised 3-year return-61.7%+5.7%+15.2%+4.2%+59.6%
GH leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

EXAS leads this category, winning 2 of 2 comparable metrics.

EXAS is the less volatile stock with a 0.05 beta — it tends to amplify market swings less than DBVT's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. EXAS currently trades 99.9% from its 52-week high vs VNRX's 12.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricVNRX logoVNRXVolitionRx LimitedDBVT logoDBVTDBV Technologies …EXAS logoEXASExact Sciences Co…ALKS logoALKSAlkermes plcGH logoGHGuardant Health, …
Beta (5Y)Sensitivity to S&P 5000.28x1.26x0.05x1.00x0.86x
52-Week HighHighest price in past year$18.80$26.18$104.98$36.60$120.74
52-Week LowLowest price in past year$0.27$7.53$38.81$25.17$36.36
% of 52W HighCurrent price vs 52-week peak+12.0%+75.3%+99.9%+95.6%+79.3%
RSI (14)Momentum oscillator 0–10030.247.476.460.555.9
Avg Volume (50D)Average daily shares traded714K252K4.3M2.2M1.9M
EXAS leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: DBVT as "Buy", EXAS as "Buy", ALKS as "Buy", GH as "Buy". Consensus price targets imply 134.8% upside for DBVT (target: $46) vs 0.1% for EXAS (target: $105).

MetricVNRX logoVNRXVolitionRx LimitedDBVT logoDBVTDBV Technologies …EXAS logoEXASExact Sciences Co…ALKS logoALKSAlkermes plcGH logoGHGuardant Health, …
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$46.33$105.00$46.00$133.14
# AnalystsCovering analysts15412830
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises00
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.1%+0.5%+0.1%
Insufficient data to determine a leader in this category.
Key Takeaway

ALKS leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). GH leads in 1 (Total Returns).

Best OverallAlkermes plc (ALKS)Leads 3 of 6 categories
Loading custom metrics...

VNRX vs DBVT vs EXAS vs ALKS vs GH: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is VNRX or DBVT or EXAS or ALKS or GH a better buy right now?

For growth investors, VolitionRx Limited (VNRX) is the stronger pick with 40.

0% revenue growth year-over-year, versus -5. 2% for Alkermes plc (ALKS). Alkermes plc (ALKS) offers the better valuation at 24. 5x trailing P/E, making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — VNRX or DBVT or EXAS or ALKS or GH?

Over the past 5 years, Alkermes plc (ALKS) delivered a total return of +61.

7%, compared to -96. 3% for VolitionRx Limited (VNRX). Over 10 years, the gap is even starker: EXAS returned +1669% versus VNRX's -96. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — VNRX or DBVT or EXAS or ALKS or GH?

By beta (market sensitivity over 5 years), Exact Sciences Corporation (EXAS) is the lower-risk stock at 0.

05β versus DBV Technologies S. A. 's 1. 26β — meaning DBVT is approximately 2296% more volatile than EXAS relative to the S&P 500. On balance sheet safety, Alkermes plc (ALKS) carries a lower debt/equity ratio of 4% versus 105% for Exact Sciences Corporation — giving it more financial flexibility in a downturn.

04

Which is growing faster — VNRX or DBVT or EXAS or ALKS or GH?

By revenue growth (latest reported year), VolitionRx Limited (VNRX) is pulling ahead at 40.

0% versus -5. 2% for Alkermes plc (ALKS). On earnings-per-share growth, the picture is similar: Exact Sciences Corporation grew EPS 80. 3% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, VNRX leads at 78. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — VNRX or DBVT or EXAS or ALKS or GH?

Alkermes plc (ALKS) is the more profitable company, earning 16.

4% net margin versus -1352. 2% for VolitionRx Limited — meaning it keeps 16. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ALKS leads at 17. 2% versus -1228. 6% for VNRX. At the gross margin level — before operating expenses — VNRX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is VNRX or DBVT or EXAS or ALKS or GH more undervalued right now?

Analyst consensus price targets imply the most upside for DBVT: 134.

8% to $46. 33.

07

Which pays a better dividend — VNRX or DBVT or EXAS or ALKS or GH?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is VNRX or DBVT or EXAS or ALKS or GH better for a retirement portfolio?

For long-horizon retirement investors, Exact Sciences Corporation (EXAS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

05), +1669% 10Y return). Both have compounded well over 10 years (EXAS: +1669%, DBVT: -87. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between VNRX and DBVT and EXAS and ALKS and GH?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: VNRX is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; EXAS is a mid-cap high-growth stock; ALKS is a small-cap quality compounder stock; GH is a mid-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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