Biotechnology
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5 / 10Stock Comparison
ZYME vs DBVT vs IMVT vs ABBV vs IQV
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Drug Manufacturers - General
Medical - Diagnostics & Research
ZYME vs DBVT vs IMVT vs ABBV vs IQV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General | Medical - Diagnostics & Research |
| Market Cap | $1.98B | $1712.35T | $5.53B | $358.42B | $30.32B |
| Revenue (TTM) | $79M | $0.00 | $0.00 | $61.16B | $16.63B |
| Net Income (TTM) | $-44.22B | $-168M | $-464M | $4.23B | $1.39B |
| Gross Margin | 97.9% | — | — | 70.2% | 26.1% |
| Operating Margin | -598.4% | — | — | 26.7% | 13.9% |
| Forward P/E | 22.4x | — | — | 14.3x | 14.1x |
| Total Debt | $18M | $22M | $98K | $69.07B | $16.17B |
| Cash & Equiv. | $41M | $194M | $714M | $5.23B | $1.98B |
ZYME vs DBVT vs IMVT vs ABBV vs IQV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Zymeworks Inc. (ZYME) | 100 | 69.8 | -30.2% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
| AbbVie Inc. (ABBV) | 100 | 218.7 | +118.7% |
| IQVIA Holdings Inc. (IQV) | 100 | 119.5 | +19.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ZYME vs DBVT vs IMVT vs ABBV vs IQV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ZYME is the #2 pick in this set and the best alternative if growth exposure and sleep-well-at-night is your priority.
- Rev growth 38.9%, EPS growth 33.3%, 3Y rev CAGR -36.4%
- Lower volatility, beta 0.97, Low D/E 6.8%, current ratio 5.52x
- Beta 0.97, current ratio 5.52x
- 38.9% revenue growth vs DBVT's -100.0%
DBVT lags the leaders in this set but could rank higher in a more targeted comparison.
Among these 5 stocks, IMVT doesn't own a clear edge in any measured category.
ABBV ranks third and is worth considering specifically for income & stability and long-term compounding.
- Dividend streak 13 yrs, beta 0.34, yield 3.2%
- 295.5% 10Y total return vs IMVT's 173.6%
- Beta 0.34 vs IMVT's 1.37
- 3.2% yield; 13-year raise streak; the other 4 pay no meaningful dividend
IQV carries the broadest edge in this set and is the clearest fit for value and quality.
- Lower P/E (14.1x vs 14.3x)
- 8.3% margin vs ZYME's -560.8%
- 4.7% ROA vs DBVT's -89.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 38.9% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (14.1x vs 14.3x) | |
| Quality / Margins | 8.3% margin vs ZYME's -560.8% | |
| Stability / Safety | Beta 0.34 vs IMVT's 1.37 | |
| Dividends | 3.2% yield; 13-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +134.6% vs ABBV's +11.3% | |
| Efficiency (ROA) | 4.7% ROA vs DBVT's -89.0% |
ZYME vs DBVT vs IMVT vs ABBV vs IQV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
ZYME vs DBVT vs IMVT vs ABBV vs IQV — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ABBV leads in 3 of 6 categories
IQV leads 1 • ZYME leads 1 • DBVT leads 0 • IMVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ABBV leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ABBV and IMVT operate at a comparable scale, with $61.2B and $0 in trailing revenue. IQV is the more profitable business, keeping 8.3% of every revenue dollar as net income compared to ZYME's -560.8%. On growth, ABBV holds the edge at +10.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $79M | $0 | $0 | $61.2B | $16.6B |
| EBITDAEarnings before interest/tax | -$47.2B | -$112M | -$487M | $24.5B | $3.5B |
| Net IncomeAfter-tax profit | -$44.2B | -$168M | -$464M | $4.2B | $1.4B |
| Free Cash FlowCash after capex | -$45.7B | -$151M | -$423M | $18.7B | $2.7B |
| Gross MarginGross profit ÷ Revenue | +97.9% | — | — | +70.2% | +26.1% |
| Operating MarginEBIT ÷ Revenue | -598.4% | — | — | +26.7% | +13.9% |
| Net MarginNet income ÷ Revenue | -560.8% | — | — | +6.9% | +8.3% |
| FCF MarginFCF ÷ Revenue | -580.2% | — | — | +30.6% | +16.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | — | — | +10.0% | +8.4% |
| EPS Growth (YoY)Latest quarter vs prior year | -96.7% | +91.5% | +19.7% | +57.4% | +15.0% |
Valuation Metrics
IQV leads this category, winning 3 of 6 comparable metrics.
Valuation Metrics
At 22.8x trailing earnings, IQV trades at a 73% valuation discount to ABBV's 85.5x P/E. On an enterprise value basis, ZYME's 0.3x EV/EBITDA is more attractive than ABBV's 15.0x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $2.0B | $1712.35T | $5.5B | $358.4B | $30.3B |
| Enterprise ValueMkt cap + debt − cash | $2.0B | $1712.35T | $4.8B | $422.3B | $44.5B |
| Trailing P/EPrice ÷ TTM EPS | -24.63x | -0.76x | -9.97x | 85.50x | 22.79x |
| Forward P/EPrice ÷ next-FY EPS est. | 22.43x | — | — | 14.28x | 14.06x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 0.56x |
| EV / EBITDAEnterprise value multiple | 0.26x | — | — | 14.96x | 12.97x |
| Price / SalesMarket cap ÷ Revenue | 18.65x | — | — | 5.86x | 1.86x |
| Price / BookPrice ÷ Book value/share | 7.46x | 0.66x | 5.83x | — | 4.67x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 20.12x | 14.78x |
Profitability & Efficiency
ABBV leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), ABBV scores 6/9 vs IMVT's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -107.5% | -130.2% | -47.1% | +62.1% | +22.1% |
| ROA (TTM)Return on assets | -36.9% | -89.0% | -44.1% | +3.1% | +4.7% |
| ROICReturn on invested capital | -25.9% | — | — | +23.9% | +8.7% |
| ROCEReturn on capital employed | -27.3% | -145.7% | -66.1% | +21.5% | +11.0% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 2 | 6 | 4 |
| Debt / EquityFinancial leverage | 0.07x | 0.13x | 0.00x | — | 2.44x |
| Net DebtTotal debt minus cash | -$23M | -$172M | -$714M | $63.8B | $14.2B |
| Cash & Equiv.Liquid assets | $41M | $194M | $714M | $5.2B | $2.0B |
| Total DebtShort + long-term debt | $18M | $22M | $98,000 | $69.1B | $16.2B |
| Interest CoverageEBIT ÷ Interest expense | -0.03x | -189.82x | — | 3.28x | 3.10x |
Total Returns (Dividends Reinvested)
ZYME leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $3,090 for DBVT. Over the past 12 months, ZYME leads with a +134.6% total return vs ABBV's +11.3%. The 3-year compound annual growth rate (CAGR) favors ZYME at 44.8% vs IQV's -2.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -0.1% | +4.9% | +5.1% | -10.1% | -20.7% |
| 1-Year ReturnPast 12 months | +134.6% | +110.4% | +96.1% | +11.3% | +16.5% |
| 3-Year ReturnCumulative with dividends | +203.7% | +19.7% | +40.9% | +50.4% | -5.9% |
| 5-Year ReturnCumulative with dividends | -12.2% | -69.1% | +62.4% | +101.3% | -23.8% |
| 10-Year ReturnCumulative with dividends | +104.6% | -87.0% | +173.6% | +295.5% | +166.5% |
| CAGR (3Y)Annualised 3-year return | +44.8% | +6.2% | +12.1% | +14.6% | -2.0% |
Risk & Volatility
Evenly matched — IMVT and ABBV each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than IMVT's 1.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs IQV's 72.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.97x | 1.26x | 1.37x | 0.34x | 1.33x |
| 52-Week HighHighest price in past year | $29.75 | $26.18 | $30.09 | $244.81 | $247.05 |
| 52-Week LowLowest price in past year | $10.86 | $7.53 | $13.36 | $176.57 | $134.65 |
| % of 52W HighCurrent price vs 52-week peak | +89.4% | +76.3% | +90.5% | +82.8% | +72.3% |
| RSI (14)Momentum oscillator 0–100 | 55.9 | 48.1 | 60.2 | 46.8 | 58.5 |
| Avg Volume (50D)Average daily shares traded | 612K | 252K | 1.4M | 5.8M | 1.6M |
Analyst Outlook
ABBV leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: ZYME as "Buy", DBVT as "Buy", IMVT as "Buy", ABBV as "Buy", IQV as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 26.3% for IQV (target: $226). ABBV is the only dividend payer here at 3.24% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $38.33 | $46.33 | $45.50 | $256.64 | $225.63 |
| # AnalystsCovering analysts | 20 | 15 | 23 | 41 | 44 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +3.2% | — |
| Dividend StreakConsecutive years of raises | — | 0 | — | 13 | 2 |
| Dividend / ShareAnnual DPS | — | — | — | $6.57 | — |
| Buyback YieldShare repurchases ÷ mkt cap | +2.1% | 0.0% | 0.0% | +0.3% | +4.1% |
ABBV leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IQV leads in 1 (Valuation Metrics). 1 tied.
ZYME vs DBVT vs IMVT vs ABBV vs IQV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ZYME or DBVT or IMVT or ABBV or IQV a better buy right now?
For growth investors, Zymeworks Inc.
(ZYME) is the stronger pick with 38. 9% revenue growth year-over-year, versus 5. 9% for IQVIA Holdings Inc. (IQV). IQVIA Holdings Inc. (IQV) offers the better valuation at 22. 8x trailing P/E (14. 1x forward), making it the more compelling value choice. Analysts rate Zymeworks Inc. (ZYME) a "Buy" — based on 20 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ZYME or DBVT or IMVT or ABBV or IQV?
On trailing P/E, IQVIA Holdings Inc.
(IQV) is the cheapest at 22. 8x versus AbbVie Inc. at 85. 5x. On forward P/E, IQVIA Holdings Inc. is actually cheaper at 14. 1x.
03Which is the better long-term investment — ZYME or DBVT or IMVT or ABBV or IQV?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +101. 3%, compared to -69. 1% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ZYME or DBVT or IMVT or ABBV or IQV?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 34β versus Immunovant, Inc. 's 1. 37β — meaning IMVT is approximately 306% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — ZYME or DBVT or IMVT or ABBV or IQV?
By revenue growth (latest reported year), Zymeworks Inc.
(ZYME) is pulling ahead at 38. 9% versus 5. 9% for IQVIA Holdings Inc. (IQV). On earnings-per-share growth, the picture is similar: Zymeworks Inc. grew EPS 33. 3% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, IQV leads at 4. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ZYME or DBVT or IMVT or ABBV or IQV?
IQVIA Holdings Inc.
(IQV) is the more profitable company, earning 8. 3% net margin versus -76. 6% for Zymeworks Inc. — meaning it keeps 8. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus -87. 3% for ZYME. At the gross margin level — before operating expenses — ZYME leads at 89. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ZYME or DBVT or IMVT or ABBV or IQV more undervalued right now?
On forward earnings alone, IQVIA Holdings Inc.
(IQV) trades at 14. 1x forward P/E versus 22. 4x for Zymeworks Inc. — 8. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 131. 8% to $46. 33.
08Which pays a better dividend — ZYME or DBVT or IMVT or ABBV or IQV?
In this comparison, ABBV (3.
2% yield) pays a dividend. ZYME, DBVT, IMVT, IQV do not pay a meaningful dividend and should not be held primarily for income.
09Is ZYME or DBVT or IMVT or ABBV or IQV better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Both have compounded well over 10 years (ABBV: +295. 5%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ZYME and DBVT and IMVT and ABBV and IQV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ZYME is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; IMVT is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock; IQV is a mid-cap quality compounder stock. ABBV pays a dividend while ZYME, DBVT, IMVT, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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