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EXAS
GH logo
GH
NTRA logo
NTRA
KO logo
KO
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Stock Comparison

EXAS vs GH vs NTRA vs KO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
EXAS
Exact Sciences Corporation

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$20.02B
5Y Perf.+20.7%
GH
Guardant Health, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$17.47B
5Y Perf.+15.7%
NTRA
Natera, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$33.14B
5Y Perf.+317.2%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$341.71B
5Y Perf.+82.5%

EXAS vs GH vs NTRA vs KO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
EXAS logoEXAS
GH logoGH
NTRA logoNTRA
KO logoKO
IndustryMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchBeverages - Non-Alcoholic
Market Cap$20.02B$17.47B$33.14B$341.71B
Revenue (TTM)$3.25B$1.08B$2.50B$49.28B
Net Income (TTM)$-208M$-433M$-226M$13.70B
Gross Margin69.7%64.9%65.2%61.7%
Operating Margin-6.4%-41.4%-13.0%29.3%
Forward P/E582.8x24.3x
Total Debt$2.52B$1.68B$214M$45.49B
Cash & Equiv.$956M$378M$1.08B$10.27B

EXAS vs GH vs NTRA vs KOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

EXAS
GH
NTRA
KO
StockJun 20Mar 26Return
Exact Sciences Corp… (EXAS)100120.7+20.7%
Guardant Health, In… (GH)100115.7+15.7%
Natera, Inc. (NTRA)100417.2+317.2%
The Coca-Cola Compa… (KO)100182.5+82.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: EXAS vs GH vs NTRA vs KO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: KO leads in 4 of 7 categories, making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Guardant Health, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. NTRA also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇KO emerged as the overall leader. Track its performance:
EXAS
Exact Sciences Corporation
The Lower-Volatility Pick

EXAS lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
GH
Guardant Health, Inc.
The Income Pick

GH is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • beta 0.96
  • Lower volatility, beta 0.96, current ratio 4.84x
  • Beta 0.96, current ratio 4.84x
  • Beta 0.96 vs NTRA's 1.22
Best for: income & stability and sleep-well-at-night
NTRA
Natera, Inc.
The Growth Play

NTRA is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth 35.9%, EPS growth 0.7%, 3Y rev CAGR 41.1%
  • 18.9% 10Y total return vs EXAS's 8.7%
  • 35.9% revenue growth vs KO's 1.9%
Best for: growth exposure and long-term compounding
KO
The Coca-Cola Company
The Value Play

KO carries the broadest edge in this set and is the clearest fit for value and quality.

  • Better valuation composite
  • 27.8% margin vs GH's -40.1%
  • 2.6% yield; 56-year raise streak; the other 3 pay no meaningful dividend
  • 13.1% ROA vs GH's -26.5%, ROIC 15.8% vs -34.9%
Best for: value and quality
See the full category breakdown
CategoryWinnerWhy
GrowthNTRA logoNTRA35.9% revenue growth vs KO's 1.9%
ValueKO logoKOBetter valuation composite
Quality / MarginsKO logoKO27.8% margin vs GH's -40.1%
Stability / SafetyGH logoGHBeta 0.96 vs NTRA's 1.22
DividendsKO logoKO2.6% yield; 56-year raise streak; the other 3 pay no meaningful dividend
Momentum (1Y)GH logoGH+160.6% vs KO's +17.7%
Efficiency (ROA)KO logoKO13.1% ROA vs GH's -26.5%, ROIC 15.8% vs -34.9%

EXAS vs GH vs NTRA vs KO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

Discover the Biotech & Healthcare Stocks Theme

These companies are key players in the Biotech & Healthcare Stocks ecosystem. See how they stack up against the rest of the sector.

Explore Theme
EXASExact Sciences Corporation
FY 2025
Screening
77.9%$2.5B
Precision Oncology
22.1%$717M
GHGuardant Health, Inc.
FY 2025
Oncology
69.6%$684M
Biopharma & Data
21.4%$210M
Screening
8.1%$80M
Licensing & Other
0.9%$9M
NTRANatera, Inc.
FY 2025
Product
99.6%$2.3B
Licensing and other
0.4%$10M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B

EXAS vs GH vs NTRA vs KO — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLKOLAGGINGGH

Income & Cash Flow (Last 12 Months)

KO leads this category, winning 3 of 6 comparable metrics.

KO is the larger business by revenue, generating $49.3B annually — 45.6x GH's $1.1B. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to GH's -40.1%. On growth, GH holds the edge at +48.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricEXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …NTRA logoNTRANatera, Inc.KO logoKOThe Coca-Cola Com…
RevenueTrailing 12 months$3.2B$1.1B$2.5B$49.3B
EBITDAEarnings before interest/tax-$41M-$409M-$313M$15.5B
Net IncomeAfter-tax profit-$208M-$433M-$226M$13.7B
Free Cash FlowCash after capex$357M-$225M$92M$12.6B
Gross MarginGross profit ÷ Revenue+69.7%+64.9%+65.2%+61.7%
Operating MarginEBIT ÷ Revenue-6.4%-41.4%-13.0%+29.3%
Net MarginNet income ÷ Revenue-6.4%-40.1%-9.0%+27.8%
FCF MarginFCF ÷ Revenue+11.0%-20.8%+3.7%+25.5%
Rev. Growth (YoY)Latest quarter vs prior year+23.1%+48.3%+38.8%+12.1%
EPS Growth (YoY)Latest quarter vs prior year+90.4%-10.4%-20.0%+18.2%
KO leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

EXAS leads this category, winning 3 of 5 comparable metrics.
MetricEXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …NTRA logoNTRANatera, Inc.KO logoKOThe Coca-Cola Com…
Market CapShares × price$20.0B$17.5B$33.1B$341.7B
Enterprise ValueMkt cap + debt − cash$21.6B$18.8B$32.3B$376.9B
Trailing P/EPrice ÷ TTM EPS-95.37x-39.69x-152.24x26.12x
Forward P/EPrice ÷ next-FY EPS est.582.83x24.27x
PEG RatioP/E ÷ EPS growth rate2.34x
EV / EBITDAEnterprise value multiple25.45x
Price / SalesMarket cap ÷ Revenue6.16x17.79x14.37x7.13x
Price / BookPrice ÷ Book value/share8.24x18.48x9.99x
Price / FCFMarket cap ÷ FCF56.10x303.73x64.52x
EXAS leads this category, winning 3 of 5 comparable metrics.

Profitability & Efficiency

KO leads this category, winning 6 of 9 comparable metrics.

KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-15 for NTRA. NTRA carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), EXAS scores 7/9 vs NTRA's 5/9, reflecting strong financial health.

MetricEXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …NTRA logoNTRANatera, Inc.KO logoKOThe Coca-Cola Com…
ROE (TTM)Return on equity-8.7%-15.1%+41.1%
ROA (TTM)Return on assets-3.5%-26.5%-10.4%+13.1%
ROICReturn on invested capital-3.6%-34.9%-36.1%+15.8%
ROCEReturn on capital employed-4.0%-29.4%-18.3%+17.3%
Piotroski ScoreFundamental quality 0–97557
Debt / EquityFinancial leverage1.05x0.13x1.33x
Net DebtTotal debt minus cash$1.6B$1.3B-$862M$35.2B
Cash & Equiv.Liquid assets$956M$378M$1.1B$10.3B
Total DebtShort + long-term debt$2.5B$1.7B$214M$45.5B
Interest CoverageEBIT ÷ Interest expense-5.47x-96.55x-34.29x10.70x
KO leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NTRA leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in NTRA five years ago would be worth $22,493 today (with dividends reinvested), compared to $8,292 for EXAS. Over the past 12 months, GH leads with a +160.6% total return vs KO's +17.7%. The 3-year compound annual growth rate (CAGR) favors NTRA at 64.4% vs EXAS's 3.6% — a key indicator of consistent wealth creation.

MetricEXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …NTRA logoNTRANatera, Inc.KO logoKOThe Coca-Cola Com…
YTD ReturnYear-to-date+3.1%+29.5%+1.1%+16.4%
1-Year ReturnPast 12 months+100.4%+160.6%+35.3%+17.7%
3-Year ReturnCumulative with dividends+11.2%+254.0%+344.2%+39.3%
5-Year ReturnCumulative with dividends-17.1%+9.6%+124.9%+65.3%
10-Year ReturnCumulative with dividends+867.8%+309.3%+1894.9%+115.0%
CAGR (3Y)Annualised 3-year return+3.6%+52.4%+64.4%+11.7%
NTRA leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — EXAS and KO each lead in 1 of 2 comparable metrics.

KO is the less volatile stock with a -0.23 beta — it tends to amplify market swings less than NTRA's 1.22 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. EXAS currently trades 99.9% from its 52-week high vs NTRA's 90.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricEXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …NTRA logoNTRANatera, Inc.KO logoKOThe Coca-Cola Com…
Beta (5Y)Sensitivity to S&P 500-0.07x0.96x1.22x-0.23x
52-Week HighHighest price in past year$104.98$135.00$256.36$84.04
52-Week LowLowest price in past year$38.81$40.35$131.81$65.35
% of 52W HighCurrent price vs 52-week peak+99.9%+97.6%+90.3%+94.5%
RSI (14)Momentum oscillator 0–10076.462.759.449.2
Avg Volume (50D)Average daily shares traded21.6M2.2M1.5M13.6M
Evenly matched — EXAS and KO each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: EXAS as "Buy", GH as "Buy", NTRA as "Buy", KO as "Buy". Consensus price targets imply 12.3% upside for NTRA (target: $260) vs 0.1% for EXAS (target: $105). KO is the only dividend payer here at 2.56% yield — a key consideration for income-focused portfolios.

MetricEXAS logoEXASExact Sciences Co…GH logoGHGuardant Health, …NTRA logoNTRANatera, Inc.KO logoKOThe Coca-Cola Com…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$105.00$147.00$259.88$86.13
# AnalystsCovering analysts41302748
Dividend YieldAnnual dividend ÷ price+2.6%
Dividend StreakConsecutive years of raises56
Dividend / ShareAnnual DPS$2.04
Buyback YieldShare repurchases ÷ mkt cap+0.1%+0.1%0.0%+0.2%
Insufficient data to determine a leader in this category.
Key Takeaway

KO leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). EXAS leads in 1 (Valuation Metrics). 1 tied.

Best OverallThe Coca-Cola Company (KO)Leads 2 of 6 categories
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EXAS vs GH vs NTRA vs KO: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is EXAS or GH or NTRA or KO a better buy right now?

For growth investors, Natera, Inc.

(NTRA) is the stronger pick with 35. 9% revenue growth year-over-year, versus 1. 9% for The Coca-Cola Company (KO). The Coca-Cola Company (KO) offers the better valuation at 26. 1x trailing P/E (24. 3x forward), making it the more compelling value choice. Analysts rate Exact Sciences Corporation (EXAS) a "Buy" — based on 41 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — EXAS or GH or NTRA or KO?

On forward P/E, The Coca-Cola Company is actually cheaper at 24.

3x.

03

Which is the better long-term investment — EXAS or GH or NTRA or KO?

Over the past 5 years, Natera, Inc.

(NTRA) delivered a total return of +124. 9%, compared to -17. 1% for Exact Sciences Corporation (EXAS). Over 10 years, the gap is even starker: NTRA returned +1895% versus KO's +115. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — EXAS or GH or NTRA or KO?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

23β versus Natera, Inc. 's 1. 22β — meaning NTRA is approximately -621% more volatile than KO relative to the S&P 500. On balance sheet safety, Natera, Inc. (NTRA) carries a lower debt/equity ratio of 13% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.

05

Which is growing faster — EXAS or GH or NTRA or KO?

By revenue growth (latest reported year), Natera, Inc.

(NTRA) is pulling ahead at 35. 9% versus 1. 9% for The Coca-Cola Company (KO). On earnings-per-share growth, the picture is similar: Exact Sciences Corporation grew EPS 80. 3% year-over-year, compared to 0. 7% for Natera, Inc.. Over a 3-year CAGR, NTRA leads at 41. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — EXAS or GH or NTRA or KO?

The Coca-Cola Company (KO) is the more profitable company, earning 27.

3% net margin versus -42. 4% for Guardant Health, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -44. 4% for GH. At the gross margin level — before operating expenses — EXAS leads at 69. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is EXAS or GH or NTRA or KO more undervalued right now?

On forward earnings alone, The Coca-Cola Company (KO) trades at 24.

3x forward P/E versus 582. 8x for Exact Sciences Corporation — 558. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NTRA: 12. 3% to $259. 88.

08

Which pays a better dividend — EXAS or GH or NTRA or KO?

In this comparison, KO (2.

6% yield) pays a dividend. EXAS, GH, NTRA do not pay a meaningful dividend and should not be held primarily for income.

09

Is EXAS or GH or NTRA or KO better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

23), 2. 6% yield, +115. 0% 10Y return). Both have compounded well over 10 years (KO: +115. 0%, GH: +309. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between EXAS and GH and NTRA and KO?

These companies operate in different sectors (EXAS (Healthcare) and GH (Healthcare) and NTRA (Healthcare) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: EXAS is a mid-cap high-growth stock; GH is a mid-cap high-growth stock; NTRA is a mid-cap high-growth stock; KO is a large-cap quality compounder stock. KO pays a dividend while EXAS, GH, NTRA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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