Alector, Inc. (ALEC) Financial Ratios
10 years of historical data (2016–2025) · Healthcare · Biotechnology
EV/EBITDA
N/A
—
5yr avg: N/A
P/FCF
N/A
—
5yr avg: 5.62
30Y Low5.6·High5.6
P/B Ratio
↓
8.20
↑+98% vs avg
5yr avg: 4.15
30Y Low1.4·High5.5
ROE
↓
-181.6%
↑-120% vs avg
5yr avg: -82.4%
30Y Low-217%·High-13%
Debt/EBITDA
N/A
—
5yr avg: N/A
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
ALEC Valuation Multiples
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
Alector, Inc. currently has a negative P/E ratio, indicating the company is operating at a loss on a trailing-twelve-month basis.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $269M | $161M | $183M | $668M | $761M | $1.7B | $1.2B | $1.1B | — | — | — |
| Enterprise Value | $240M | $131M | $192M | $633M | $650M | $1.4B | $1.2B | $1.0B | — | — | — |
| P/E Ratio → | -1.76 | — | — | — | — | — | — | — | — | — | — |
| P/S Ratio | 12.80 | 7.63 | 1.82 | 6.88 | 5.70 | 8.02 | 55.76 | 50.13 | — | — | — |
| P/B Ratio | 8.20 | 5.24 | 1.44 | 4.98 | 3.55 | 5.52 | 4.40 | 5.46 | — | — | — |
| P/FCF | — | — | — | — | — | 5.62 | — | — | — | — | — |
| P/OCF | — | — | — | — | — | 5.56 | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
ALEC EV Ratios
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 6.23 | 1.91 | 6.52 | 4.87 | 6.66 | 55.82 | 48.17 | — | — | — |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | 4.67 | — | — | — | — | — |
ALEC Profitability
Margins and return-on-capital ratios measuring operating efficiency
Alector, Inc. earns an operating margin of -741.3%. Operating margins have compressed from -156.3% to -741.3% over the past 3 years, signaling potential cost pressures or competitive headwinds. A negative ROE of -181.6% indicates the company is currently destroying shareholder equity.
Margins
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | — | — | 100.0% | 90.9% | 100.0% | 8.5% | -643.5% | -373.8% | -163.9% | -700.8% | -3187.0% |
| Operating Margin | -741.3% | -741.3% | -144.2% | -156.3% | -103.2% | -18.0% | -925.1% | -539.2% | -207.0% | -874.9% | -3637.5% |
| Net Profit Margin | -679.2% | -679.2% | -118.4% | -134.3% | -99.8% | -17.5% | -901.6% | -496.7% | -188.8% | -869.6% | -3632.2% |
Return on Capital
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -181.6% | -181.6% | -91.2% | -74.8% | -51.8% | -12.8% | -82.3% | -216.5% | — | — | — |
| ROA | -37.5% | -37.5% | -21.8% | -18.5% | -16.6% | -5.6% | -41.8% | -28.9% | -19.2% | -22.4% | -27.9% |
| ROIC | -170.3% | -170.3% | -92.6% | -112.7% | -168.6% | -19.5% | -69.4% | — | — | — | — |
| ROCE | -55.0% | -55.0% | -36.8% | -26.7% | -20.1% | -6.8% | -50.0% | -34.9% | -22.7% | -25.0% | -28.8% |
ALEC Leverage & Debt
Solvency and debt-coverage ratios — lower is generally safer
The company holds a net cash position — cash of $66M exceeds total debt of $36M, providing substantial financial flexibility for buybacks, acquisitions, or weathering downturns.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 1.18 | 1.18 | 0.34 | 0.29 | 0.20 | 0.16 | 0.19 | 0.25 | — | — | — |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | -0.96 | 0.07 | -0.27 | -0.52 | -0.94 | 0.00 | -0.21 | — | — | — |
| Net Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Debt / FCF | — | — | — | — | — | -0.95 | — | — | -0.52 | — | — |
| Interest Coverage | — | — | — | — | — | — | — | — | — | — | — |
Net cash position: cash ($66M) exceeds total debt ($36M)
ALEC Liquidity & Efficiency
Short-term solvency ratios and asset-utilisation metrics
Alector, Inc.'s current ratio of 3.83x is well above the 1.0 safety threshold, indicating strong short-term liquidity with ample room to cover current liabilities. The current ratio has improved from 3.18x to 3.83x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.83 | 3.83 | 3.40 | 3.18 | 7.74 | 5.37 | 6.19 | 5.77 | 22.48 | 8.50 | 33.90 |
| Quick Ratio | 3.83 | 3.83 | 3.40 | 3.18 | 7.74 | 5.37 | 6.19 | 5.77 | 22.48 | 8.50 | 33.90 |
| Cash Ratio | 3.68 | 3.68 | 3.31 | 3.08 | 7.60 | 5.27 | 6.07 | 5.70 | 22.27 | 1.18 | 33.67 |
| Asset Turnover | — | 0.07 | 0.21 | 0.16 | 0.17 | 0.25 | 0.04 | 0.05 | 0.09 | 0.02 | 0.01 |
| Inventory Turnover | — | — | — | — | — | — | — | — | — | — | — |
| Days Sales Outstanding | — | — | — | — | 7.07 | 13.03 | — | — | — | 19568.10 | 191.27 |
ALEC Shareholder Yields
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Alector, Inc. does not currently pay a dividend and has no material buyback yield, reinvesting earnings back into the business.
Dividends
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
Total Shareholder Return Metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | 17.8% | — | — | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — | — | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — | — | — |
| Shares Outstanding | — | $103M | $97M | $84M | $82M | $80M | $78M | $62M | $68M | $51M | $8M |
Peer Comparison
Compare ALEC with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
 ALECYou | $269M | -1.8 | — | — | — | -741.3% | -181.6% | -170.3% | — |
 PRTA | $567M | -2.3 | — | — | 61.8% | -1905.8% | -63.6% | -2099.8% | — |
 ACAD | $4B | 9.9 | 26.9 | 36.7 | 91.7% | 9.8% | 39.9% | 10.0% | 0.4 |
 SAVA | $94M | -3.8 | — | — | — | — | -17.2% | -634.1% | — |
 AVXL | $289M | -5.8 | — | — | — | — | -43.1% | — | — |
 INMB | $38M | -0.8 | — | — | 100.0% | -61738.0% | -165.2% | -407.4% | — |
 BIIB | $28B | 21.7 | 11.4 | 13.8 | 70.5% | 19.1% | 7.4% | 6.5% | 2.5 |
 IONS | $13B | -31.9 | — | — | 98.3% | -40.5% | -70.7% | -12.8% | — |
 ARVN | $652M | -8.0 | — | — | 98.0% | -43.8% | -16.2% | -22.4% | — |
 DNLI | $3B | -6.6 | — | — | — | — | -45.7% | -42.8% | — |
 PTGX | $6B | -48.2 | — | 113.4 | 97.3% | -343.6% | -20.2% | -21.8% | — |
| Healthcare Median | — | 22.3 | 14.4 | 18.5 | 63.9% | -5.2% | -33.7% | -11.2% | 3.3 |
Peer selection based on competitive and market overlap. Compare multiple stocks →
Download Financial Ratios Data
Includes 30+ ratios · 10 years · Updated daily
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Quick answers to the most common questions about buying ALEC stock.
What is Alector, Inc.'s P/E ratio?
Alector, Inc.'s current P/E ratio is -1.8x. This places it at the 50th percentile of its historical range.
What is Alector, Inc.'s ROE?
Alector, Inc.'s return on equity (ROE) is -181.6%. The historical average is -101.6%.
Is ALEC stock overvalued?
Based on historical data, Alector, Inc. is trading at a P/E of -1.8x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
What are Alector, Inc.'s profit margins?
Alector, Inc. has -741.3% operating margin.