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BioCryst Pharmaceuticals, Inc. (BCRX) 10-Year Financial Performance & Capital Metrics

BCRX • • Industrial / General
HealthcareBiotechnologyAutoimmune & Inflammatory DiseasesDermatology & Autoimmune
AboutBioCryst Pharmaceuticals, Inc., a biotechnology company, discovers novel, oral, and small-molecule medicines. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat hereditary angioedema. It is also developing BCX9930, an oral factor D inhibitor, which is in Phase II clinical trial for complement-mediated diseases; BCX9250, an oral activin receptor-like kinase-2 inhibitor that is in Phase I clinical trial to treat fibrodysplasia ossificans progressiva; and Galidesivir, a RNA dependent-RNA polymerase inhibitor, which is in Phase I clinical trial to treat various RNA viruses, including Marburg, Yellow Fever, Ebola, and Zika. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd.; Seqirus UK Limited; Shionogi & Co., Ltd.; Green Cross Corporation; Mundipharma International Holdings Limited; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and The University of Alabama at Birmingham, as well as Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.Show more
  • Revenue $451M +36.0%
  • EBITDA -$1M +98.7%
  • Net Income -$89M +60.8%
  • EPS (Diluted) -0.43 +63.6%
  • Gross Margin 97.23% -1.4%
  • EBITDA Margin -0.29% +99.1%
  • Operating Margin -0.56% +98.2%
  • Net Margin -19.72% +71.2%
  • ROE -
  • ROIC -0.73% +98.1%
  • Debt/Equity -
  • Interest Coverage -0.03 +97.3%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 56.0%

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y41.91%
5Y55.97%
3Y42.07%
TTM45.38%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM92.91%

EPS CAGR

10Y-
5Y-
3Y-
TTM91.59%

ROCE

10Y Avg-68.94%
5Y Avg-44.02%
3Y Avg-19.42%
Latest-0.73%

Peer Comparison

Dermatology & Autoimmune
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Quality & Returns
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TTM Growth
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
AUPHAurinia Pharmaceuticals Inc.1.96B14.87378.3733.97%29.28%21.28%2.25%0.21
ARGXargenx SE50.33B813.2463.6378.6%23.34%15.14%0.01
INVAInnoviva, Inc.1.48B19.7654.8915.54%32.78%12.61%12.75%0.65
GLPGGalapagos N.V.2.24B34.0330.3814.99%-151.94%-15.16%0.00
PTGXProtagonist Therapeutics, Inc.5.3B84.7520.046.24%21.94%7.11%3.45%0.02
ALMSAlumis Inc. Common Stock2.84B24.17-2.33-11.08%-63.71%0.12
PHATPhathom Pharmaceuticals, Inc.1.17B14.98-2.8380.01%-186.53%
ORKAOruka Therapeutics, Inc.1.57B32.50-6.51-22.44%0.00

Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+48.26M26.35M25.19M20.65M48.84M17.81M157.17M270.83M331.41M450.71M
Revenue Growth %2.55%-0.45%-0.04%-0.18%1.36%-0.64%7.82%0.72%0.22%0.36%
Cost of Goods Sold+1.9M2.7M1.7M471K4.1M1.68M7.26M6.59M4.66M12.48M
COGS % of Revenue0.04%0.1%0.07%0.02%0.08%0.09%0.05%0.02%0.01%0.03%
Gross Profit+46.36M23.65M23.48M20.18M44.73M16.14M149.91M264.23M326.75M438.23M
Gross Margin %0.96%0.9%0.93%0.98%0.92%0.91%0.95%0.98%0.99%0.97%
Gross Profit Growth %2.44%-0.49%-0.01%-0.14%1.22%-0.64%8.29%0.76%0.24%0.34%
Operating Expenses+85.81M72.26M80.89M114.4M144.19M190.89M327.63M412.67M430.46M440.77M
OpEx % of Revenue1.78%2.74%3.21%5.54%2.95%10.72%2.08%1.52%1.3%0.98%
Selling, General & Admin13.05M11.25M13.93M29.51M37.12M67.93M118.82M159.37M213.89M266.13M
SG&A % of Revenue0.27%0.43%0.55%1.43%0.76%3.81%0.76%0.59%0.65%0.59%
Research & Development72.76M61.01M66.96M84.89M107.07M122.96M208.81M253.3M216.57M174.64M
R&D % of Revenue1.51%2.32%2.66%4.11%2.19%6.9%1.33%0.94%0.65%0.39%
Other Operating Expenses0000000000
Operating Income+-39.44M-48.61M-57.41M-94.22M-99.45M-174.76M-177.72M-148.44M-103.71M-2.54M
Operating Margin %-0.82%-1.84%-2.28%-4.56%-2.04%-9.81%-1.13%-0.55%-0.31%-0.01%
Operating Income Growth %0.14%-0.23%-0.18%-0.64%-0.06%-0.76%-0.02%0.16%0.3%0.98%
EBITDA+-39.26M-48.12M-56.71M-93.45M-98.73M-174.01M-176.94M-147M-102.05M-1.3M
EBITDA Margin %-0.81%-1.83%-2.25%-4.52%-2.02%-9.77%-1.13%-0.54%-0.31%-0%
EBITDA Growth %0.14%-0.23%-0.18%-0.65%-0.06%-0.76%-0.02%0.17%0.31%0.99%
D&A (Non-Cash Add-back)180K483K704K770K724K748K777K1.44M1.66M1.25M
EBIT-37.82M-48.66M-57.22M-92.08M-97M-168.31M-122.52M-145.29M-117.99M11.56M
Net Interest Income+-4.67M-5.69M-7.55M-6.92M-9.96M-5.08M-59.23M-93.97M-92.46M-83.77M
Interest Income535K793K1.01M2.25M1.93M9.42M62K5.13M15.78M14.75M
Interest Expense5.2M6.49M8.56M9.18M11.89M14.5M59.29M99.09M108.24M98.52M
Other Income/Expense-3.58M-6.54M-8.37M-7.03M-9.44M-8.06M-4.09M-95.95M-122.52M-84.41M
Pretax Income+-43.02M-55.14M-65.78M-101.25M-108.9M-182.81M-181.81M-244.38M-226.23M-86.95M
Pretax Margin %-0.89%-2.09%-2.61%-4.9%-2.23%-10.26%-1.16%-0.9%-0.68%-0.19%
Income Tax+0000002.25M2.73M310K1.93M
Effective Tax Rate %1%1%1%1%1%1%1.01%1.01%1%1.02%
Net Income+-43.02M-55.14M-65.78M-101.25M-108.9M-182.81M-184.06M-247.12M-226.54M-88.88M
Net Margin %-0.89%-2.09%-2.61%-4.9%-2.23%-10.26%-1.17%-0.91%-0.68%-0.2%
Net Income Growth %0.05%-0.28%-0.19%-0.54%-0.08%-0.68%-0.01%-0.34%0.08%0.61%
Net Income (Continuing)-43.02M-55.14M-65.78M-101.25M-108.9M-182.81M-184.06M-247.12M-226.54M-88.88M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-0.59-0.75-0.78-0.98-0.94-1.09-1.03-1.33-1.18-0.43
EPS Growth %0.13%-0.27%-0.04%-0.26%0.04%-0.16%0.06%-0.29%0.11%0.64%
EPS (Basic)-0.59-0.75-0.78-0.98-0.94-1.09-1.03-1.33-1.18-0.43
Diluted Shares Outstanding72.9M73.7M84.45M103.19M115.6M167.27M179.12M185.91M192.2M206.7M
Basic Shares Outstanding72.9M73.7M84.45M103.19M115.6M167.27M179.12M185.91M192.2M206.7M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+65.99M66.99M125.39M114.35M164.34M323.8M566.14M516.5M495.97M421.97M
Cash & Short-Term Investments99.25M63.58M155.69M126.84M136.23M300.37M507.6M424.31M388.99M321.06M
Cash Only28.9M22.1M50.28M26.73M114.17M272.13M504.39M304.77M110.64M104.92M
Short-Term Investments22.66M32.55M64.11M77.74M22.05M28.24M3.21M119.54M278.34M216.14M
Accounts Receivable6.24M8.77M6.12M4.29M22.15M8.65M29.41M50.6M56.95M79.07M
Days Sales Outstanding47.22121.4488.6575.87165.52177.1768.3168.1962.7264.03
Inventory1.61M500K-37.8M1.65M07.04M15.79M27.53M28.68M8.09M
Days Inventory Outstanding310.3367.62-1.28K-1.53K793.461.52K2.25K236.42
Other Current Assets1.7M1.63M3.5M1.54M1.55M2.22M3.35M14.06M21.35M13.75M
Total Non-Current Assets+58.56M22.86M52.87M32.49M10.94M10.91M22.02M33.5M20.99M68.45M
Property, Plant & Equipment5.15M9.92M9.55M9.13M7.35M7.11M15.19M8.62M20.91M19.79M
Fixed Asset Turnover9.37x2.66x2.64x2.26x6.65x2.50x10.35x31.43x15.85x22.78x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments47.68M8.93M41.3M22.38M006.83M18.08M021.72M
Other Non-Current Assets5.73M4.01M2.03M978K3.59M3.8M06.81M80K26.94M
Total Assets+124.56M89.85M178.26M146.84M175.28M334.71M588.15M550M516.96M490.42M
Asset Turnover0.39x0.29x0.14x0.14x0.28x0.05x0.27x0.49x0.64x0.92x
Asset Growth %-0.09%-0.28%0.98%-0.18%0.19%0.91%0.76%-0.06%-0.06%-0.05%
Total Current Liabilities+64.45M54.36M74.84M69.48M92.33M105.65M103.72M105.51M149.99M160.38M
Accounts Payable9.31M4.27M6.34M7.77M13.99M18.71M27.81M14.36M20.89M11.64M
Days Payables Outstanding1.79K577.321.36K6.02K1.24K4.08K1.4K794.651.64K340.41
Short-Term Debt27.8M28.24M35.15M33.7M38.58M30M00035.45M
Deferred Revenue (Current)1000K1000K1000K221K1000K150K1000K1000K00
Other Current Liabilities22.56M19.4M21.89M23.08M6.19M44.58M52M36.46M86.59M64.66M
Current Ratio1.02x1.23x1.68x1.65x1.78x3.06x5.46x4.90x3.31x2.63x
Quick Ratio1.00x1.22x2.18x1.62x1.78x3.00x5.31x4.63x3.12x2.58x
Cash Conversion Cycle-1.43K-388.26--4.67K--2.37K-535.52797.58672.75-39.96
Total Non-Current Liabilities+12.38M33.91M19.66M28.13M44.7M248.32M591.42M739.08M822.5M805.97M
Long-Term Debt022.78M16.75M25.37M41.29M244.45M585.46M733.28M811.26M795.92M
Capital Lease Obligations2.38M2.7M2.75M2.7M3.41M3.87M5.96M5.8M11.23M10.05M
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities329K244K155K54K000000
Total Liabilities76.83M88.27M94.49M97.61M137.03M353.98M695.14M844.6M972.49M966.35M
Total Debt+32.38M53.72M54.72M61.82M84.65M279.5M593.24M741.45M825.15M841.42M
Net Debt3.48M31.62M4.44M35.09M-29.52M7.38M88.85M436.69M714.5M736.5M
Debt / Equity----2.21x-----
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage-7.59x-7.49x-6.70x-10.27x-8.36x-12.05x-3.00x-1.50x-0.96x-0.03x
Total Equity+-510.92M-566.06M-631.84M-731.97M38.25M-19.26M-106.99M-294.6M-455.53M-475.93M
Equity Growth %-0.09%-0.11%-0.12%-0.16%1.05%-1.5%-4.55%-1.75%-0.55%-0.04%
Book Value per Share-7.01-7.68-7.48-7.090.33-0.12-0.60-1.58-2.37-2.30
Total Shareholders' Equity-510.92M-566.06M-631.84M-731.97M38.25M-19.26M-106.99M-294.6M-455.53M-475.93M
Common Stock734K738K984K1.1M1.54M1.77M1.84M1.88M2.06M2.08M
Retained Earnings-510.92M-566.06M-631.84M-731.97M-840.63M-1.02B-1.21B-1.45B-1.68B-1.77B
Treasury Stock0000000000
Accumulated OCI-206K-12K-243K-297K39K3K177K26K1.34M921K
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-13.12M-53.44M-41.14M-92.56M-89.58M-137.22M-142.16M-161.85M-95.14M-52.02M
Operating CF Margin %-0.27%-2.03%-1.63%-4.48%-1.83%-7.7%-0.9%-0.6%-0.29%-0.12%
Operating CF Growth %0.66%-3.07%0.23%-1.25%0.03%-0.53%-0.04%-0.14%0.41%0.45%
Net Income-43.02M-55.14M-65.78M-101.25M-108.9M-182.81M-184.06M-247.12M-226.54M-88.88M
Depreciation & Amortization180K483K704K770K724K748K777K1.44M1.66M1.25M
Stock-Based Compensation9.71M8.49M12.62M9.4M0034.64M44.7M55.62M65.41M
Deferred Taxes564K-271K1.11M1.17M000000
Other Non-Cash Items439K558K876K885K19.46M17.98M-1.64M98.07M106.53M57.48M
Working Capital Changes19.02M-7.55M9.33M-3.53M-872K26.88M8.12M-58.95M-32.4M-87.28M
Change in Receivables-7.38M-2.52M2.65M568K-17.85M13.9M-20.82M-21.47M-6.09M-22.7M
Change in Inventory-929K1.11M500K-1.65M1.65M-7.04M-8.77M-12.42M-1.45M-4.16M
Change in Payables6.82M-10.52M3.84M4.49M11.74M17.36M39.41M-22.36M-16.81M-62.38M
Cash from Investing+-18M23.34M-66.38M4.77M77.93M-6.86M15.8M-128.24M-131.5M52.59M
Capital Expenditures-5.12M-5.28M-328K-366K-343K-514K-2.38M-1.35M-2.17M-1.12M
CapEx % of Revenue0.11%0.2%0.01%0.02%0.01%0.03%0.02%0%0.01%0%
Acquisitions----------
Investments----------
Other Investing-1.46M66K-1.74M-366K01K0000
Cash from Financing+5.48M23.3M135.7M62.5M99.1M302.7M359.67M88.03M32.48M-5.76M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing5.48M317K1.58M2.85M0124.71M15.73M14.77M-26.24M-4.09M
Net Change in Cash----------
Free Cash Flow+-18.24M-58.72M-41.47M-92.93M-89.93M-137.73M-144.54M-163.2M-97.31M-53.14M
FCF Margin %-0.38%-2.23%-1.65%-4.5%-1.84%-7.73%-0.92%-0.6%-0.29%-0.12%
FCF Growth %0.53%-2.22%0.29%-1.24%0.03%-0.53%-0.05%-0.13%0.4%0.45%
FCF per Share-0.25-0.80-0.49-0.90-0.78-0.82-0.81-0.88-0.51-0.26
FCF Conversion (FCF/Net Income)0.30x0.97x0.63x0.91x0.82x0.75x0.77x0.65x0.42x0.59x
Interest Paid000000900K022.14M30.38M
Taxes Paid000000118K3.54M1.43M1.6M

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-----284.68%-1925.37%----
Return on Invested Capital (ROIC)--------179.63%-38.79%-0.73%
Gross Margin96.07%89.76%93.24%97.72%91.6%90.59%95.38%97.57%98.59%97.23%
Net Margin-89.15%-209.25%-261.18%-490.25%-222.99%-1026.35%-117.11%-91.25%-68.36%-19.72%
Debt / Equity----2.21x-----
Interest Coverage-7.59x-7.49x-6.70x-10.27x-8.36x-12.05x-3.00x-1.50x-0.96x-0.03x
FCF Conversion0.30x0.97x0.63x0.91x0.82x0.75x0.77x0.65x0.42x0.59x
Revenue Growth254.62%-45.39%-4.43%-18%136.45%-63.53%782.38%72.31%22.37%36%

Revenue by Segment

20172018201920202021202220232024
Product--17.53M--267.71M324.7M442.67M
Product Growth------21.29%36.33%
Collaborative And Other Research And Development-----214K6.72M8.04M
Collaborative And Other Research And Development Growth------3038.32%19.77%
Milestone--------
Milestone Growth--------
Collaborative and Other Research and Development-2.55M25M-5.92M---
Collaborative and Other Research and Development Growth--879.58%-----
Service---757K----
Service Growth--------
Royalty-6.1M6.3M-----
Royalty Growth--3.31%-----
Supplemental NDA for RAPIVAB5M-------
Supplemental NDA for RAPIVAB Growth--------
RAPIVAB2M-------
RAPIVAB Growth--------

Frequently Asked Questions

Growth & Financials

BioCryst Pharmaceuticals, Inc. (BCRX) reported $599.8M in revenue for fiscal year 2024. This represents a 2954% increase from $19.6M in 2011.

BioCryst Pharmaceuticals, Inc. (BCRX) grew revenue by 36.0% over the past year. This is strong growth.

BioCryst Pharmaceuticals, Inc. (BCRX) reported a net loss of $8.8M for fiscal year 2024.

Dividend & Returns

BioCryst Pharmaceuticals, Inc. (BCRX) generated $47.3M in free cash flow for fiscal year 2024. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

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