| Name | Market Cap | Current Price | P/E Ratio | Revenue Growth 1Y | Net Margin | ROE | FCF Yield | Debt/Equity |
|---|---|---|---|---|---|---|---|---|
| CORTCorcept Therapeutics Incorporated | 3.78B | 35.70 | 43.54 | 12.79% | 13.01% | 15.3% | 3.75% | 0.01 |
| BMRNBioMarin Pharmaceutical Inc. | 11.86B | 61.73 | 34.29 | 10.83% | 5.73% | 6.11% | 0.10 | |
| VRTXVertex Pharmaceuticals Incorporated | 126.19B | 496.83 | 32.43 | 8.9% | 31.35% | 21.22% | 2.53% | 0.20 |
| CPRXCatalyst Pharmaceuticals, Inc. | 2.83B | 23.08 | 13.74 | 19.78% | 36.39% | 22.46% | 7.38% | 0.00 |
| HRMYHarmony Biosciences Holdings, Inc. | 1.65B | 28.54 | 10.53 | 21.51% | 18.27% | 18.24% | 21.12% | 0.02 |
| PTCTPTC Therapeutics, Inc. | 5.45B | 68.19 | 8.76 | 114.51% | 42.25% | |||
| BCRXBioCryst Pharmaceuticals, Inc. | 1.86B | 8.75 | 7.23 | 94.1% | 30.16% | 18.63% | ||
| RAREUltragenyx Pharmaceutical Inc. | 2.26B | 23.39 | -3.72 | 29.01% | -91.95% | -35.88% | 0.15 |
Analyze head-to-head performance against top industry competitors across valuation, growth, and profitability metrics.
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 81.32M | 159.2M | 251.25M | 306.49M | 353.87M | 365.98M | 401.86M | 482.38M | 675.04M | 761.41M |
| Revenue Growth % | 61.72% | 95.77% | 57.82% | 21.99% | 15.46% | 3.42% | 9.8% | 20.04% | 39.94% | 12.79% |
| Cost of Goods Sold | 2.06M | 3.55M | 5.21M | 5.5M | 5.58M | 5.28M | 5.38M | 6.48M | 10.88M | 12.98M |
| COGS % of Revenue | 2.53% | 2.23% | 2.08% | 1.8% | 1.58% | 1.44% | 1.34% | 1.34% | 1.61% | 1.7% |
| Gross Profit | 79.26M | 155.65M | 246.03M | 300.98M | 348.29M | 360.7M | 396.47M | 475.89M | 664.16M | 748.43M |
| Gross Margin % | 97.47% | 97.77% | 97.92% | 98.2% | 98.42% | 98.56% | 98.66% | 98.66% | 98.39% | 98.3% |
| Gross Profit Growth % | 62.01% | 96.37% | 58.07% | 22.33% | 15.72% | 3.56% | 9.92% | 20.03% | 39.56% | 12.69% |
| Operating Expenses | 69.08M | 102.79M | 156.54M | 189.38M | 220.09M | 236.22M | 283.84M | 368.61M | 527.21M | 703.63M |
| OpEx % of Revenue | 84.95% | 64.57% | 62.3% | 61.79% | 62.19% | 64.54% | 70.63% | 76.42% | 78.1% | 92.41% |
| Selling, General & Admin | 45.24M | 62.42M | 81.29M | 100.36M | 105.33M | 122.36M | 152.85M | 184.26M | 280.32M | 448.73M |
| SG&A % of Revenue | 55.63% | 39.21% | 32.35% | 32.75% | 29.76% | 33.43% | 38.04% | 38.2% | 41.53% | 58.93% |
| Research & Development | 23.84M | 40.38M | 75.25M | 89.02M | 114.76M | 113.86M | 130.99M | 184.35M | 246.89M | 254.91M |
| R&D % of Revenue | 29.32% | 25.36% | 29.95% | 29.04% | 32.43% | 31.11% | 32.6% | 38.22% | 36.57% | 33.48% |
| Other Operating Expenses | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Operating Income | 10.18M | 52.85M | 89.5M | 111.61M | 128.2M | 124.48M | 112.63M | 107.28M | 136.95M | 44.8M |
| Operating Margin % | 12.52% | 33.2% | 35.62% | 36.41% | 36.23% | 34.01% | 28.03% | 22.24% | 20.29% | 5.88% |
| Operating Income Growth % | 395.64% | 419.26% | 69.32% | 24.7% | 14.87% | -2.91% | -9.51% | -4.75% | 27.66% | -67.29% |
| EBITDA | 10.27M | 52.96M | 89.73M | 113.78M | 130.44M | 127.54M | 113.89M | 108.32M | 138.29M | 46.69M |
| EBITDA Margin % | 12.62% | 33.27% | 35.71% | 37.12% | 36.86% | 34.85% | 28.34% | 22.46% | 20.49% | 6.13% |
| EBITDA Growth % | 412.23% | 415.89% | 69.43% | 26.8% | 14.64% | -2.22% | -10.7% | -4.89% | 27.66% | -66.24% |
| D&A (Non-Cash Add-back) | 87K | 106K | 236K | 2.17M | 2.24M | 3.07M | 1.26M | 1.04M | 1.34M | 1.89M |
| EBIT | 10.07M | 52.85M | 89.5M | 111.61M | 128.2M | 125.01M | 112.63M | 107.28M | 136.95M | 66.46M |
| Net Interest Income | -2.04M | -49K | 2.66M | 5.07M | 3.4M | 529K | 3.56M | 17.27M | 24.54M | 0 |
| Interest Income | 0 | 0 | 2.66M | 5.07M | 3.4M | 529K | 3.56M | 17.27M | 24.54M | 0 |
| Interest Expense | 2.04M | 49K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Income/Expense | -2.04M | -49K | 2.66M | 5.07M | 3.4M | 529K | 3.56M | 17.27M | 24.54M | 21.67M |
| Pretax Income | 8.14M | 52.81M | 92.15M | 116.68M | 131.6M | 125.01M | 116.19M | 124.56M | 161.49M | 66.46M |
| Pretax Margin % | 10.01% | 33.17% | 36.68% | 38.07% | 37.19% | 34.16% | 28.91% | 25.82% | 23.92% | 8.73% |
| Income Tax | 0 | -76.32M | 16.74M | 22.5M | 25.59M | 12.49M | 14.77M | 18.42M | 20.28M | -33.19M |
| Effective Tax Rate % | 100% | 244.52% | 81.83% | 80.72% | 80.55% | 90.01% | 87.29% | 85.21% | 86.53% | 149.94% |
| Net Income | 8.14M | 129.12M | 75.41M | 94.18M | 106.01M | 112.51M | 101.42M | 106.14M | 139.73M | 99.65M |
| Net Margin % | 10.01% | 81.11% | 30.01% | 30.73% | 29.96% | 30.74% | 25.24% | 22% | 20.7% | 13.09% |
| Net Income Growth % | 227.03% | 1486.27% | -41.6% | 24.89% | 12.56% | 6.13% | -9.86% | 4.66% | 31.65% | -28.68% |
| Net Income (Continuing) | 8.14M | 129.12M | 75.41M | 94.18M | 106.01M | 112.51M | 101.42M | 106.14M | 141.21M | 99.65M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | 0.07 | 1.04 | 0.60 | 0.77 | 0.85 | 0.89 | 0.87 | 0.94 | 1.23 | 0.82 |
| EPS Growth % | 216.67% | 1385.71% | -42.31% | 28.33% | 10.39% | 4.71% | -2.25% | 8.05% | 30.85% | -33.33% |
| EPS (Basic) | 0.07 | 1.14 | 0.60 | 0.82 | 0.92 | 0.97 | 0.95 | 1.02 | 1.35 | 0.95 |
| Diluted Shares Outstanding | 116.14M | 124.52M | 126.69M | 122.57M | 124.19M | 125.96M | 115.97M | 111.74M | 113.48M | 119.99M |
| Basic Shares Outstanding | 110.57M | 113.53M | 125.68M | 114.35M | 115.41M | 115.65M | 106.79M | 103.56M | 103.23M | 103.86M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - |
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 65.69M | 140.6M | 240.59M | 307.36M | 478.5M | 266.46M | 499.25M | 458.64M | 471.6M | 485.46M |
| Cash & Short-Term Investments | 51.54M | 104.03M | 206.76M | 275.96M | 440.7M | 223.53M | 431.67M | 368.22M | 383.33M | 372.15M |
| Cash Only | 51.54M | 104.03M | 206.76M | 31.27M | 76.19M | 77.62M | 66.33M | 135.55M | 127.67M | 120.5M |
| Short-Term Investments | 0 | 0 | 0 | 244.69M | 364.51M | 145.92M | 365.34M | 232.67M | 255.67M | 251.66M |
| Accounts Receivable | 9.86M | 28.2M | 17.59M | 19.93M | 26.2M | 29.02M | 46.86M | 56.82M | 58.08M | 59.79M |
| Days Sales Outstanding | 44.26 | 64.64 | 25.55 | 23.73 | 27.02 | 28.95 | 42.56 | 43 | 31.4 | 28.66 |
| Inventory | 2.33M | 8.38M | 16.24M | 5.42M | 4.91M | 4.99M | 6.1M | 7.73M | 12.41M | 12.87M |
| Days Inventory Outstanding | 413.06 | 860.23 | 1.14K | 359.69 | 321.06 | 344.75 | 413.46 | 435.34 | 416.32 | 361.93 |
| Other Current Assets | 1.96M | 2.67M | 7.74M | 6.04M | 6.7M | 8.91M | 14.62M | 25.86M | 8.29M | 40.66M |
| Total Non-Current Assets | 3.06M | 79.94M | 71.1M | 104.95M | 93.23M | 157.29M | 84.18M | 162.88M | 368.95M | 351.19M |
| Property, Plant & Equipment | 205K | 518K | 655K | 4.5M | 4.18M | 1.52M | 1.78M | 315K | 8.01M | 6.47M |
| Fixed Asset Turnover | 396.69x | 307.34x | 383.58x | 68.17x | 84.58x | 241.41x | 226.27x | 1531.35x | 84.24x | 117.63x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 15.28M | 0 | 39.35M | 36.2M | 112.28M | 4.95M | 57.18M | 219.83M | 0 |
| Other Non-Current Assets | 2.86M | 3.24M | 7.79M | 15.43M | 21.25M | 16.05M | 15.99M | 14.79M | 10.19M | 176.52M |
| Total Assets | 68.75M | 220.54M | 311.69M | 412.31M | 571.73M | 423.76M | 583.43M | 621.52M | 840.55M | 836.65M |
| Asset Turnover | 1.18x | 0.72x | 0.81x | 0.74x | 0.62x | 0.86x | 0.69x | 0.78x | 0.80x | 0.91x |
| Asset Growth % | 32.38% | 220.77% | 41.33% | 32.28% | 38.66% | -25.88% | 37.68% | 6.53% | 35.24% | -0.46% |
| Total Current Liabilities | 27.37M | 29.57M | 35.81M | 38.84M | 47.49M | 47.54M | 72.49M | 104.5M | 140.77M | 166.09M |
| Accounts Payable | 2.29M | 8.58M | 8.27M | 7.54M | 10.55M | 6.91M | 11.98M | 17.4M | 15.38M | 40.44M |
| Days Payables Outstanding | 406.15 | 881.07 | 578.54 | 499.82 | 690.11 | 477.45 | 811.74 | 979.72 | 515.74 | 1.14K |
| Short-Term Debt | 14.66M | 0 | 0 | 1.56M | 2.05M | 526K | 1.14M | 151K | 829K | 1.08M |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 5.72M | 12.42M | 17.89M | 16.94M | 24.75M | 26.25M | 43.77M | 59.69M | 82.65M | 124.56M |
| Current Ratio | 2.40x | 4.75x | 6.72x | 7.91x | 10.07x | 5.60x | 6.89x | 4.39x | 3.35x | 2.92x |
| Quick Ratio | 2.31x | 4.47x | 6.26x | 7.77x | 9.97x | 5.50x | 6.80x | 4.31x | 3.26x | 2.85x |
| Cash Conversion Cycle | 51.17 | 43.8 | 583.79 | -116.39 | -342.03 | -103.75 | -355.72 | -501.38 | -68.02 | -746.96 |
| Total Non-Current Liabilities | 0 | 0 | 239K | 2.29M | 899K | 409K | 9.1M | 10.31M | 20.19M | 22.76M |
| Long-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.02M |
| Capital Lease Obligations | 0 | 0 | 0 | 1.9M | 501K | 0 | 0 | 0 | 6.11M | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 0 | 0 | 239K | 386K | 398K | 409K | 9.1M | 10.31M | 14.08M | 17.74M |
| Total Liabilities | 27.37M | 29.57M | 35.81M | 41.13M | 48.39M | 47.95M | 81.59M | 114.81M | 160.96M | 188.85M |
| Total Debt | 14.66M | 0 | 0 | 3.46M | 2.55M | 526K | 1.14M | 151K | 6.94M | 6.11M |
| Net Debt | -36.87M | -104.03M | -206.76M | -27.81M | -73.64M | -77.09M | -65.19M | -135.4M | -120.73M | -114.39M |
| Debt / Equity | 0.35x | - | - | 0.01x | 0.00x | 0.00x | 0.00x | 0.00x | 0.01x | 0.01x |
| Debt / EBITDA | 1.43x | - | - | 0.03x | 0.02x | 0.00x | 0.01x | 0.00x | 0.05x | 0.13x |
| Net Debt / EBITDA | -3.59x | -1.96x | -2.30x | -0.24x | -0.56x | -0.60x | -0.57x | -1.25x | -0.87x | -2.45x |
| Interest Coverage | 4.99x | 1078.67x | - | - | - | - | - | - | - | - |
| Total Equity | 41.38M | 190.97M | 275.88M | 371.18M | 523.34M | 375.81M | 501.84M | 506.7M | 679.59M | 647.8M |
| Equity Growth % | 123.69% | 361.51% | 44.46% | 34.54% | 40.99% | -28.19% | 33.54% | 0.97% | 34.12% | -4.68% |
| Book Value per Share | 0.36 | 1.53 | 2.18 | 3.03 | 4.21 | 2.98 | 4.33 | 4.53 | 5.99 | 5.40 |
| Total Shareholders' Equity | 41.38M | 190.97M | 275.88M | 371.18M | 523.34M | 375.81M | 501.84M | 506.7M | 679.59M | 647.8M |
| Common Stock | 113K | 115K | 117K | 120K | 122K | 127K | 131K | 133K | 136K | 140K |
| Retained Earnings | -322.27M | -193.15M | -117.74M | -23.55M | 82.46M | 194.97M | 296.39M | 402.53M | 543.74M | 643.39M |
| Treasury Stock | 0 | 0 | -23.66M | -62.7M | -75.8M | -410.41M | -456.15M | -635.08M | -696.17M | 0 |
| Accumulated OCI | -452K | -75K | -70K | 261K | 415K | -227K | -869K | 609K | -217K | 2.26M |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | 18.39M | 60.94M | 115.67M | 136.12M | 151.97M | 167.89M | 120.32M | 127.04M | 198.07M | 142M |
| Operating CF Margin % | 22.62% | 38.28% | 46.04% | 44.41% | 42.94% | 45.87% | 29.94% | 26.34% | 29.34% | 18.65% |
| Operating CF Growth % | 487.57% | 231.33% | 89.82% | 17.68% | 11.65% | 10.48% | -28.33% | 5.58% | 55.91% | -28.31% |
| Net Income | 8.14M | 129.12M | 75.41M | 94.18M | 106.01M | 112.51M | 101.42M | 106.14M | 141.21M | 98.17M |
| Depreciation & Amortization | 87K | 106K | 236K | 2.17M | 2.24M | 3.07M | 3.45M | 2.36M | 1.34M | 1.89M |
| Stock-Based Compensation | 7.06M | 13.36M | 23.75M | 29.31M | 33.54M | 42.93M | 42.44M | 48.94M | 61.35M | 84.5M |
| Deferred Taxes | 0 | -76.7M | 14.07M | 16.88M | 14.09M | 4.35M | -33.91M | -29.49M | -40.19M | 0 |
| Other Non-Cash Items | 1.95M | 763K | -1.72M | -1.74M | 1.45M | 5.09M | 1.38M | -9.13M | -10.94M | -15M |
| Working Capital Changes | 1.16M | -5.71M | 3.93M | -4.69M | -5.36M | -57K | 5.54M | 8.22M | 45.3M | -27.57M |
| Change in Receivables | -3.64M | -5.44M | -2.29M | -2.34M | -6.27M | -1.43M | -17.43M | -10.07M | 1.15M | -5.81M |
| Change in Inventory | -682K | -2.26M | -7.78M | -1.04M | -3.51M | 3.44M | 1.2M | 1.26M | 305K | -7.48M |
| Change in Payables | 965K | 6.29M | -389K | -735K | 3.16M | -3.6M | 4.76M | 5.78M | -2.25M | 25.07M |
| Cash from Investing | -194K | -73.46M | -90.77M | -117.83M | -119.26M | 136.13M | -114.33M | 90.91M | -177.6M | 69.76M |
| Capital Expenditures | -194K | -419K | -298K | -1.09M | -1.24M | -469K | -413K | -139K | -2.17M | -211K |
| CapEx % of Revenue | 0.24% | 0.26% | 0.12% | 0.36% | 0.35% | 0.13% | 0.1% | 0.03% | 0.32% | 0.03% |
| Acquisitions | 0 | 0 | 0 | 116.74M | 118.03M | -136.59M | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | -73.04M | -90.47M | -116.74M | -118.03M | 136.59M | 0 | 0 | 0 | 0 |
| Cash from Financing | -7.1M | -7.95M | -14.34M | -28.64M | 12.21M | -302.59M | -17.28M | -148.72M | -28.35M | -220.37M |
| Debt Issued (Net) | -14.78M | -15.13M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 0 | 0 | -1000K | -1000K | -1000K | -1000K | 0 | -1000K | -1000K | -1000K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | -23.66M | -30.98M | -9.95M | -295.99M | 0 | -145.43M | -15.66M | -245.86M |
| Other Financing | 7.68M | 7.18M | 9.32M | 2.33M | 22.16M | -6.61M | -17.28M | -3.29M | -22.3M | 25.49M |
| Net Change in Cash | 11.1M | -20.47M | 10.56M | -10.36M | 44.92M | 1.43M | -11.29M | 69.22M | -7.89M | -7.17M |
| Free Cash Flow | 18.2M | 60.52M | 115.37M | 135.03M | 150.73M | 167.42M | 119.91M | 126.9M | 195.9M | 141.78M |
| FCF Margin % | 22.38% | 38.01% | 45.92% | 44.06% | 42.59% | 45.75% | 29.84% | 26.31% | 29.02% | 18.62% |
| FCF Growth % | 484.55% | 232.56% | 90.64% | 17.04% | 11.63% | 11.07% | -28.38% | 5.83% | 54.37% | -27.62% |
| FCF per Share | 0.16 | 0.49 | 0.91 | 1.10 | 1.21 | 1.33 | 1.03 | 1.14 | 1.73 | 1.18 |
| FCF Conversion (FCF/Net Income) | 2.26x | 0.47x | 1.53x | 1.45x | 1.43x | 1.49x | 1.19x | 1.20x | 1.42x | 1.42x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 40K | 377K | 1.35M | 6.74M | 10.86M | 9.1M | 39.75M | 47.6M | 60.27M | 0 |
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | 27.19% | 111.15% | 32.31% | 29.11% | 23.7% | 25.03% | 23.11% | 21.05% | 23.56% | 15.01% |
| Return on Invested Capital (ROIC) | - | 86.69% | 86.02% | 40.58% | 24.25% | 24.95% | 22.97% | 19.92% | 22.09% | 6.15% |
| Gross Margin | 97.47% | 97.77% | 97.92% | 98.2% | 98.42% | 98.56% | 98.66% | 98.66% | 98.39% | 98.3% |
| Net Margin | 10.01% | 81.11% | 30.01% | 30.73% | 29.96% | 30.74% | 25.24% | 22% | 20.7% | 13.09% |
| Debt / Equity | 0.35x | - | - | 0.01x | 0.00x | 0.00x | 0.00x | 0.00x | 0.01x | 0.01x |
| Interest Coverage | 4.99x | 1078.67x | - | - | - | - | - | - | - | - |
| FCF Conversion | 2.26x | 0.47x | 1.53x | 1.45x | 1.43x | 1.49x | 1.19x | 1.20x | 1.42x | 1.42x |
| Revenue Growth | 61.72% | 95.77% | 57.82% | 21.99% | 15.46% | 3.42% | 9.8% | 20.04% | 39.94% | 12.79% |
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