Harmony Biosciences Holdings, Inc. (HRMY) Revenue History
Annual and quarterly revenue from 2018 to 2025
Compound Annual Growth Rate (CAGR)
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HRMY Revenue Growth
Revenue Breakdown
HRMY's revenue distribution by segment and geography
By Geography
HRMY Revenue Analysis (2018–2025)
As of May 6, 2026, Harmony Biosciences Holdings, Inc. (HRMY) generated trailing twelve-month (TTM) revenue of $868.5 million, reflecting exceptional growth of +21.1% year-over-year. The most recent quarter (Q4 2025) recorded $243.8 million in revenue, up 1.8% sequentially.
Looking at the longer-term picture, HRMY's 5-year compound annual growth rate (CAGR) stands at +40.3%, indicating outstanding long-term growth trajectory. The company achieved its highest annual revenue of $868.5 million in 2025, representing a new all-time high.
When compared to Healthcare sector peers including JAZZ (+9.2% YoY), AVPT (+26.9% YoY), and AXSM (+63.9% YoY), HRMY has underperformed the peer group in terms of revenue growth. Compare HRMY vs JAZZ →
HRMY Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| HRMYCurrent | $868M | +21.1% | +40.3% | 24.0% | |
 JAZZ | $4.3B | +9.2% | +12.5% | 5.3% | |
 AVPT | $419M | +26.9% | +22.6% | 7.9% | |
 AXSM | $638M | +63.9% | - | -26.5% | |
 INVA | $425M | +14.5% | +4.8% | 38.5% | |
 SUPN | $719M | +16.3% | +6.7% | -5.1% |
HRMY Historical Revenue Data (2018–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $868.5M | +21.5% | $670.1M | 77.2% | $208.5M | 24.0% |
| 2024 | $714.7M | +22.8% | $557.9M | 78.1% | $190.8M | 26.7% |
| 2023 | $582.0M | +32.9% | $460.8M | 79.2% | $192.0M | 33.0% |
| 2022 | $437.9M | +43.4% | $354.4M | 80.9% | $120.2M | 27.4% |
| 2021 | $305.4M | +91.2% | $249.9M | 81.8% | $87.5M | 28.7% |
| 2020 | $159.7M | +2564.6% | $132.0M | 82.6% | $17.0M | 10.6% |
| 2019 | $6.0M | - | $4.4M | 73.7% | $-145,904,000 | -2433.8% |
| 2018 | $0 | - | $-184,000 | - | $-41,439,000 | - |
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Start ComparisonHRMY — Frequently Asked Questions
Quick answers to the most common questions about buying HRMY stock.
Is HRMY's revenue growth accelerating or slowing?
HRMY revenue is accelerating at +21.1% year-over-year, exceeding the 5-year CAGR of +40.3%. TTM revenue reached $868M. Growth momentum has increased versus prior periods.
What is HRMY's long-term revenue growth rate?
Harmony Biosciences Holdings, Inc.'s 5-year revenue CAGR of +40.3% reflects the sustained expansion pattern. Current YoY growth of +21.1% is above this long-term average.
How is HRMY's revenue distributed by segment?
HRMY reports revenue by product line and geographic region. Annual and quarterly breakdowns from 2018-2025 are available for download. Segment mix reveals concentration and diversification trends.