Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in IOVA held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 31.1M | $109.1M | +5.3% | 8.693% | 0.00% |
| 2 | MHR FUND MANAGEMENT LLC | 29.0M | $101.7M | 0.0% | 8.102% | 7.43% |
| 3 | STATE STREET CORP | 17.4M | $61.2M | -13.5% | 4.880% | 0.00% |
| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 16.6M | $58.3M | — | 4.648% | 0.00% |
| 5 | TWO SIGMA INVESTMENTS, LP | 13.7M | $48.0M | +211.2% | 3.828% | 0.04% |
| 6 | VANGUARD PORTFOLIO MANAGEMENT LLC | 11.7M | $41.1M | — | 3.273% | 0.00% |
| 7 | MILLENNIUM MANAGEMENT LLC | 9.4M | $33.0M | +34.8% | 2.633% | 0.02% |
| 8 | GOLDMAN SACHS GROUP INC | 8.8M | $30.7M | +1.8% | 2.450% | 0.00% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 8.6M | $30.1M | +7.3% | 2.398% | 0.00% |
| 10 | Invenomic Capital Management LP | 8.5M | $29.8M | -29.0% | 2.376% | 1.38% |
| 11 | BANK OF AMERICA CORP /DE/ | 8.5M | $29.8M | -40.5% | 2.375% | 0.00% |
| 12 | D. E. Shaw & Co., Inc. | 8.0M | $28.1M | +109.3% | 2.242% | 0.03% |
| 13 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 6.7M | $23.5M | -8.2% | 1.873% | 0.00% |
| 14 | Palo Alto Investors LP | 6.3M | $22.3M | -10.8% | 1.776% | 3.41% |
| 15 | MORGAN STANLEY | 6.2M | $21.8M | -32.5% | 1.734% | 0.00% |
| 16 | Nuveen, LLC | 3.7M | $12.9M | +164.4% | 1.025% | 0.00% |
| 17 | NORTHERN TRUST CORP | 2.9M | $10.1M | +11.5% | 0.804% | 0.00% |
| 18 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 2.8M | $9.8M | +1.1% | 0.779% | 0.00% |
| 19 | DIMENSIONAL FUND ADVISORS LP | 2.6M | $9.3M | +71.9% | 0.740% | 0.00% |
| 20 | MARSHALL WACE, LLP | 2.4M | $8.3M | — | 0.659% | 0.01% |
| 21 | VANGUARD FIDUCIARY TRUST CO | 2.2M | $7.7M | — | 0.611% | 0.00% |
| 22 | Long Focus Capital Management, LLC | 2.1M | $7.4M | -75.6% | 0.587% | 0.21% |
| 23 | WELLS FARGO & COMPANY/MN | 2.1M | $7.3M | +3.9% | 0.579% | 0.00% |
| 24 | Orion Investment Co | 2.1M | $7.3M | +11.2% | 0.578% | 2.30% |
| 25 | Rhenman & Partners Asset Management AB | 2.1M | $7.2M | +28.8% | 0.575% | 0.89% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in IOVA — a direct measure of their conviction.
Filings activity in IOVA during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new IOVA position in Q1 2026
Institutions that fully closed their IOVA position in Q1 2026
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 274 | +6.6% | 60.87% | +14.18 pp | $888M | +30% |
| Q4 2025 | 257 | +5.8% | 46.69% | +15.20 pp | $681M | +48% |
| Q3 2025 | 243 | 2.0% | 31.49% | +6.52 pp | $459M | +26% |
| Q2 2025 | 248 | 16% | 24.97% | 27.40 pp | $364M | 52% |
| Q1 2025 | 294 | 0.7% | 52.37% | 98.34 pp | $764M | 65% |
| Q4 2024 | 296 | +5.7% | 150.71% | +9.25 pp | $2.20B | +6.5% |
| Q3 2024 | 280 | 4.4% | 141.46% | +18.36 pp | $2.06B | +15% |
| Q2 2024 | 293 | — | 123.10% | — | $1.80B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying IOVA stock.
Based on Q1 2026 13F filings, institutional ownership of Iovance Biotherapeutics, Inc. stands at 60.9%, held across 274 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of IOVA, with approximately 31,080,505 shares worth $0.11B as of Q1 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of IOVA, including TWO SIGMA INVESTMENTS, LP, MILLENNIUM MANAGEMENT LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for IOVA is 73 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
63 institutions opened new positions in IOVA during Q1 2026, while 46 fully exited. 180 added to existing positions and 28 trimmed.
IOVA institutional ownership rose by 14.18 percentage points quarter-over-quarter, with a net change of +17 holders.
The top 10 institutions account for 61.2% of all reported 13F value in IOVA, and the top 25 account for 85.1%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Iovance Biotherapeutics, Inc. (IOVA) Institutional Ownership