Last 31 quarters of trend data · Healthcare · Metabolic & Cardiovascular Biotech
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 | Q1 '21 | Q4 '20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/B Ratio | — | 4.07 | 4.25 | 2.94 | 2.62 | 2.70 | 2.03 | 1.77 | 2.43 | 4.82 | 3.93 | 5.86 | 7.85 | 3.83 | 2.25 | 3.39 | 4.36 | 3.92 | 3.92 | 4.10 | 3.46 |
| — | +50.7% | +109.1% | +65.9% | +7.7% | -44.1% | -48.2% | -69.8% | -69.0% | +25.9% | +74.3% | +73.0% | +79.8% | -2.3% | -42.6% | -17.3% | +26.1% | +7.3% | -42.9% | -19.8% | -29.2% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 | Q1 '21 | Q4 '20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Operating Margin | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Net Margin | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 | Q1 '21 | Q4 '20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | — | -8.2% | -6.7% | -7.7% | -9.4% | -9.5% | -6.8% | -7.7% | -9.9% | -6.6% | -6.7% | -8.2% | -6.9% | -14.5% | -18.6% | -16.5% | -17.6% | -11.6% | -12.4% | -6.0% | -10.9% |
| — | +13.1% | +1.8% | +0.1% | +4.7% | -43.1% | -1.1% | +5.4% | -43.4% | +54.2% | +63.7% | +50.5% | +61.0% | -24.4% | -49.7% | -175.8% | -61.8% | -5.9% | +15.0% | +37.9% | +5.0% | |
| ROA | — | -7.7% | -6.2% | -7.1% | -8.5% | -8.6% | -6.3% | -7.1% | -9.1% | -6.1% | -6.1% | -7.3% | -6.3% | -12.6% | -15.4% | -14.2% | -15.5% | -10.5% | -11.7% | -5.7% | -10.4% |
| — | +10.7% | +1.2% | +0.1% | +6.1% | -41.5% | -2.6% | +2.4% | -44.9% | +51.5% | +60.2% | +48.6% | +59.5% | -19.3% | -32.0% | -150.6% | -49.3% | -2.0% | +13.3% | +36.7% | +4.3% | |
| ROIC | — | -8.3% | -6.8% | -8.8% | -12.9% | -12.5% | -12.6% | -15.3% | -13.9% | -13.0% | -19.6% | -26.6% | -56.0% | — | — | -221.3% | -87.8% | -36.7% | -35.0% | -17.0% | -26.4% |
| — | +33.2% | +45.8% | +42.7% | +7.0% | +4.0% | +35.6% | +42.3% | +75.2% | — | — | +88.0% | +36.2% | — | — | -1198.7% | -232.1% | -54.6% | -58.5% | -24.2% | +35.3% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 | Q2 '21 | Q1 '21 | Q4 '20 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | — | 0.00 | 0.04 | 0.03 | 0.05 | 0.05 | 0.05 | 0.04 | 0.05 | 0.04 | 0.04 | 0.09 | 0.03 | 0.03 | 0.07 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 |
| — | -97.5% | -20.2% | -21.1% | -1.1% | +9.5% | +7.0% | -49.7% | +46.6% | +42.9% | -41.8% | +749.2% | +273.9% | +299.7% | +876.5% | +36.5% | +28.1% | +20.8% | — | +277.2% | +960.0% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | — | 15.83 | 12.66 | 16.80 | 19.38 | 17.25 | 24.89 | 30.12 | 29.27 | 20.25 | 29.78 | 20.84 | 18.61 | 14.97 | 6.90 | 7.60 | 7.70 | 9.42 | 14.35 | 25.23 | 20.70 |
| — | -8.2% | -49.1% | -44.2% | -33.8% | -14.8% | -16.4% | +44.5% | +57.3% | +35.2% | +331.7% | +174.2% | +141.6% | +58.9% | -51.9% | -69.9% | -62.8% | -62.0% | +31.8% | +65.7% | +40.5% | |
| Quick Ratio | — | 15.83 | 12.66 | 16.80 | 19.38 | 17.25 | 24.89 | 30.12 | 29.27 | 20.25 | 29.78 | 20.84 | 18.61 | 14.97 | 6.90 | 7.60 | 7.70 | 9.42 | 14.35 | 25.23 | 20.70 |
| — | -8.2% | -49.1% | -44.2% | -33.8% | -14.8% | -16.4% | +44.5% | +57.3% | +35.2% | +331.7% | +174.2% | +141.6% | +58.9% | -51.9% | -69.9% | -62.8% | -62.0% | +31.8% | +65.7% | +40.5% | |
| Interest Coverage | — | -82.63 | -69.00 | -70.09 | -65.02 | -65.57 | -53.40 | -60.50 | -68.98 | -52.49 | -41.57 | -62.92 | -70.22 | -111.39 | -520.64 | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 31 years · Updated daily
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Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Akero Therapeutics, Inc.'s business trajectory between earnings reports.