The firm continues to burn cash at an unsustainable rate, with free cash flow deficits reaching $10.5 million in 2025Q4, necessitating potential future equity dilution to sustain operations.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 |
|---|
| Cash from Operations | -33.38M | -29.76M | -21.03M | -20.94M | -20.76M | -16.47M | -11.57M | -9.13M | -8.96M | -6.59M | -5.37M | -13.95M | -10.56M | -8.83M | -3.9M | -3.49M | -358.11K | -75.18K |
| Operating CF Margin % | - | - | - | - | - | - | - | - | - | - | - | -793702.84% | -26297.9% | -1395.93% | -809.39% | -232824.27% | - | - |
| Operating CF Growth % | -196.88% | -41.52% | -0.43% | -0.87% | -26.03% | -42.36% | -26.75% | -1.86% | -35.91% | -22.69% | 61.48% | -32.19% | -19.54% | -126.41% | -11.67% | -875.22% | -376.36% | - |
| Net Income | -37.64M | -34.77M | -25.5M | -30.09M | -26.96M | -20.61M | -17.83M | -17.24M | -11.4M | -8.12M | -6.37M | -12.76M | -14.66M | -10.78M | -5.08M | -3.44M | -1.09M | -122.86K |
| Depreciation & Amortization | 16K | 16K | 17K | 23K | 8K | 23K | 46.52K | 52.79K | 44.2K | 128.99K | 303.48K | 272.63K | 564.46K | 472.93K | 130.55K | 15.62K | 0 | 0 |
| Stock-Based Compensation | 2.08M | 2.65M | 2.29M | 4.62M | 6.79M | 5.27M | 3.02M | 8.84M | 2.46M | 786.55K | 876.19K | 840.1K | 698.66K | 1.44M | 121.81K | 140.06K | 30.4K | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 2.36M | 0 | 0 | 760.16K | -712.86K | -3.47M | -489.37K | 663.1K | -91.93K | 3.53M | 0 | 0 |
| Other Non-Cash Items | 722K | 0 | 1.72M | 2.99M | 3K | 0 | 939.2K | 5.81K | 0 | 192.82K | 1.6M | 840.1K | 3.05M | 389.77K | 121.81K | -3.44M | 73K | 0 |
| Working Capital Changes | 1.44M | 2.35M | 448K | 1.52M | -599K | -1.16M | -111.35K | -791.3K | -64.41K | -339.89K | -1.07M | 326.1K | 277.45K | -1.01M | 897.64K | -297.8K | 625.42K | 47.68K |
| Change in Receivables | 0 | 0 | 0 | 743K | 329K | -437K | 104.72K | -221.56K | -159.82K | -358.28K | 0 | 321.05K | -368.17K | -352.27K | -140.44K | -1.22K | 0 | 0 |
| Change in Inventory | 0 | -983K | -611K | 2.54M | -329K | 437K | -104.72K | 0 | 0 | 0 | 0 | 9.28K | -39.79K | -149.95K | -29.88K | -92.03K | 0 | 0 |
| Change in Payables | 1.4M | 3.61M | -127K | -2.16M | 1.25M | 128K | 1.3M | -60.16K | 18.43K | 80.58K | -560.13K | 301.4K | 346.21K | -58.58K | 3.45K | 64.77K | 0 | 0 |
| Cash from Investing | -14K | -23K | -19K | -14K | -4.73M | -9K | -9.37K | -7.63K | -110.91K | 0 | -9.21K | -288.42K | -343.26K | -489.81K | -134.58K | -136.93K | 0 | 0 |
| Capital Expenditures | -14K | -23K | -19K | -14K | -27K | -9K | -9.37K | -7.63K | -110.91K | 0 | -9.21K | -130.74K | -343.26K | -489.81K | -134.58K | -136.93K | 0 | 0 |
| CapEx % of Revenue | - | - | - | - | - | - | - | - | - | - | - | 7436.58% | 855.19% | 77.43% | 27.93% | 9128.73% | - | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -157.68K | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Financing | 0 | 0 | 3.67M | -1.48M | 0 | 113.3M | 38.55M | 11.34M | 12.29M | 10.78M | 4.7M | 9.46M | 13.06M | 13.94M | 3.85M | 5.53M | 284K | 159.54K |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -98.48K | 0 | -5.08K | -183.92K | 182K | 5K |
| Equity Issued (Net) | 0 | 0 | 3.67M | -1.48M | 0 | 69.67M | 38.57M | 11.34M | 12.29M | 10.03M | 4.7M | 9.46M | 13.16M | 13.94M | 3.85M | 5.71M | 102K | 154.54K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | -1.48M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 0 | 0 | 0 | 0 | 0 | 43.64M | -13.82K | 0 | 0 | 749.23K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Net Change in Cash | -33.4M | -29.79M | -17.38M | -22.43M | -25.49M | 96.82M | 26.97M | 2.2M | 3.22M | 4.19M | -687.93K | -4.78M | 2.16M | 4.62M | -185.62K | 1.9M | -74.11K | 84.36K |
| Free Cash Flow | -33.4M | -29.79M | -21.05M | -20.95M | -20.79M | -16.48M | -11.58M | -9.14M | -9.07M | -6.59M | -5.38M | -14.08M | -10.9M | -9.32M | -4.03M | -3.63M | -358.11K | -75.18K |
| FCF Margin % | - | - | - | - | - | - | - | - | - | - | - | -801139.42% | -27153.09% | -1473.36% | -837.32% | -241953% | - | - |
| FCF Growth % | -49.68% | -41.5% | -0.45% | -0.81% | -26.13% | -42.33% | -26.75% | -0.7% | -37.59% | -22.48% | 61.77% | -29.23% | -16.94% | -131% | -11.17% | -913.46% | -376.34% | - |
| FCF per Share | -3.87 | -3.46 | -2.51 | -2.49 | -2.46 | -2.11 | -15.36 | -16.13 | -32.73 | -101.47 | -328.80 | -1337.64 | -1224.16 | -1625.08 | -874.79 | -1074.71 | -161.02 | -22.21 |
| FCF Conversion (FCF/Net Income) | 0.89x | 0.86x | 0.82x | 0.70x | 0.77x | 0.80x | 0.65x | 0.53x | 0.79x | 0.81x | 0.84x | 0.89x | 0.72x | 0.82x | 0.77x | 1.01x | 0.33x | 0.61x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 250 | 0 |
Clinical trial funding dependency
According to the provided financial data, the OCF/NI ratio has fluctuated significantly, reaching 1.00 in 2026Q1, which suggests that the company's reported net losses are closely tracking actual cash outflows as the firm lacks the non-cash revenue streams that typically create a gap between accounting and cash.
The alignment between net income and operating cash flow is a direct consequence of the company's pre-revenue status, where expenses are almost entirely cash-based. Investors should monitor this relationship, as any future divergence would likely indicate the introduction of non-cash accounting items or changes in working capital management rather than operational profitability.
As reported in financial statements, Atossa Therapeutics has consistently generated negative free cash flow, with quarterly outflows reaching $10.5 million in 2025Q4, highlighting the company's total reliance on external capital to sustain its ongoing clinical research and development activities without any offsetting commercial revenue generation.
The trajectory of free cash flow remains deeply negative, reflecting the high fixed costs associated with clinical trial execution. This trend appears unlikely to reverse until the company achieves a major licensing milestone or regulatory approval, necessitating continued scrutiny of the remaining cash runway.
Based on reported figures, working capital changes have been highly erratic, swinging from a $1.9 million inflow in 2025Q3 to a $1.5 million outflow in 2024Q4, which suggests that the company's cash position is sensitive to the timing of vendor payments and clinical trial-related accruals.
These fluctuations in working capital appear to be driven by the timing of payments to clinical research organizations rather than underlying operational efficiency. Analysts should interpret these swings as temporary timing differences that do not alter the fundamental reality of the company's ongoing cash burn.
As indicated by the company's cash flow statements, stock-based compensation has been a consistent feature, peaking at $796,000 in 2025Q2, which effectively masks the true economic cost of operations by substituting equity for cash to retain talent during the critical Phase II development phase.
While stock-based compensation preserves immediate liquidity, it represents a real cost to shareholders through dilution. Investors should adjust their cash burn models to account for this non-cash expense, as it suggests that the company's operational costs are higher than the headline cash flow figures imply.
Quick answers to the most common questions about buying ATOS stock.
Atossa Therapeutics, Inc. (ATOS) generated $-29.8M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Atossa Therapeutics, Inc. (ATOS) reported negative free cash flow of $29.8M in 2025, indicating capital requirements exceeded cash from operations.
Atossa Therapeutics, Inc. (ATOS) spent $0.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.