Free cash flow remains deeply negative, with quarterly outflows consistently exceeding $50 million as the firm funds its capital-intensive manufacturing build-out.
| Cash from Operations | -273.32M | -283.57M | -206.27M | -145.59M | -112.31M | -117.86M | -117.76M | -101.48M | -25.85M | -16.36M | -9.85M | -3.33M |
| Operating CF Margin % | - | -375.27% | -2038.25% | -8574.03% | -1813.17% | -7820.9% | -6866.36% | -3489.82% | -2472.62% | -966.33% | -812.62% | -3533.51% |
| Operating CF Growth % | -94.87% | -37.47% | -41.68% | -29.63% | 4.71% | -0.09% | -16.04% | -292.63% | -57.99% | -66.11% | -196.17% | - |
| Net Income | -288.83M | -287.53M | -220.66M | -208.38M | -148.84M | -142.1M | -142.09M | -123.85M | -31.11M | -19.73M | -12.55M | -7.46M |
| Depreciation & Amortization | 12.18M | 9.81M | 7.72M | 6.57M | 7.42M | 8.46M | 5.66M | 4.61M | 1.1M | 1.01M | 478K | 3.64M |
| Stock-Based Compensation | 15.14M | 14.44M | 15.47M | 11.2M | 12.01M | 9.94M | 20.11M | 30.21M | 5.03M | 3.15M | 2.26M | 0 |
| Deferred Taxes | -789K | -286K | -185K | -986K | -268K | -72K | -1.34M | -399K | -5.21M | 0 | 0 | 0 |
| Other Non-Cash Items | -13.16M | 32.1M | 15.04M | 45.72M | 13.39M | 1.77M | -1.5M | 4.14M | -1.07M | 5.17M | 1.2M | 916.23K |
| Working Capital Changes | 2.27M | -52.11M | -23.66M | 292K | 3.97M | 4.14M | 1.41M | -16.2M | 5.42M | -795K | -1.23M | -413.95K |
| Change in Receivables | -13.46M | -24.21M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -413.95K |
| Change in Inventory | 15.14M | -40.34M | -4.23M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | -1.74M | 1.3M | 1.59M | -509K | 22K | -1.82M | 1.44M | -1.45M | 8.65M | 434K | 507K | 0 |
| Cash from Investing | 314.16M | 158.46M | -394.55M | -10.99M | -10.84M | -8.86M | -14.68M | -18.67M | -7.65M | -2.88M | -1.85M | -754.14K |
| Capital Expenditures | -15.52M | 0 | -22.07M | -10.99M | -10.84M | -8.86M | -14.68M | -18.34M | -8.77M | -2.88M | -1.85M | -762.07K |
| CapEx % of Revenue | 16.76% | 25.26% | 218.13% | 647% | 175.02% | 587.72% | 856.03% | 630.71% | 839.09% | 169.88% | 153.05% | 809.74% |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -6.06M | -27.13M | -12.74M | 0 | 0 | 0 | 0 | -327K | 1.13M | 0 | 0 | 7.92K |
| Cash from Financing | -6.4M | -4.34M | 589.55M | -883K | 223.61M | 284.06M | 74.42M | 108.86M | 117.49M | 127.69M | 32.22M | 12.23M |
| Debt Issued (Net) | -2.06M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 0 | 0 | 549.98M | 0 | 163.85M | 245.9M | 154.16M | 224.78M | 156.92M | 127.69M | 32.22M | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -3.18M | 0 | 0 | 0 |
| Other Financing | -4.34M | -4.34M | 39.58M | -883K | 59.76M | 38.16M | -79.75M | -115.92M | 0 | 0 | 0 | 12.23M |
| Net Change in Cash | 35.17M | -123.17M | -11.53M | -142.43M | 72.08M | 156.59M | -57.34M | -6.13M | 86.98M | 109.01M | 17.86M | 8.15M |
| Free Cash Flow | -291.52M | -303.32M | -241.09M | -156.57M | -123.15M | -126.72M | -132.44M | -120.15M | -34.62M | -19.24M | -11.7M | -4.09M |
| FCF Margin % | -314.86% | -401.4% | -2382.31% | -9221.02% | -1988.2% | -8408.63% | -7722.39% | -4131.77% | -3311.71% | -1136.21% | -965.68% | -4343.25% |
| FCF Growth % | -2.7% | -25.81% | -53.98% | -27.14% | 2.82% | 4.32% | -10.23% | -247.07% | -79.97% | -64.35% | -186.33% | - |
| FCF per Share | -1.10 | -1.14 | -0.94 | -0.90 | -1.30 | -1.76 | -2.57 | -2.79 | -1.10 | -1.40 | -0.85 | -0.30 |
| FCF Conversion (FCF/Net Income) | 1.01x | 0.98x | 0.93x | 0.70x | 0.75x | 0.83x | 0.83x | 0.82x | 0.83x | 0.83x | 0.78x | 0.45x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 1.03M | 0 | 2.39M | 551K | 471K | 364K | 1.84M | 1.53M | 0 | 0 | 0 | 0 |
Pre-commercial cash burn intensity
As reported in financial statements, Autolus exhibits a persistent disconnect between net losses and operating cash outflows, with the OCF/NI ratio fluctuating significantly, reaching 0.91 in 2026Q1, which suggests that non-cash items and working capital swings are primary drivers of the company's reported cash position.
The volatility in the OCF/NI ratio indicates that cash flow is heavily influenced by timing differences in milestone recognition and operational accruals rather than core business performance. Investors should monitor whether this conversion stabilizes as the company moves toward commercialization, as current figures appear to reflect the inherent instability of a pre-revenue clinical entity.
Based on Autolus's reported figures, the free cash flow trajectory remains deeply negative, with quarterly outflows consistently exceeding $50 million in most periods, underscoring the substantial capital requirements necessary to sustain clinical development and the ongoing maintenance of the Stevenage manufacturing facility ahead of commercial launch.
The consistent FCF burn highlights the company's reliance on external financing to bridge the gap between R&D intensity and the absence of product-derived cash inflows. This trend suggests that the company's liquidity position remains highly sensitive to the timing of future capital raises or strategic partnership milestones.
According to recent SEC filings, Autolus's capital expenditure profile is characterized by lumpy, project-based investments, with CapEx/Revenue ratios reaching as high as 383.2% in 2024Q4, reflecting the heavy upfront commitment to building out the proprietary 'Nucleus' manufacturing capabilities required for long-term commercial viability.
The high capital intensity relative to revenue suggests that the company is prioritizing vertical integration to mitigate supply chain risks, though this strategy places significant pressure on current cash reserves. Analysts should evaluate whether these investments will yield the expected operational efficiencies once commercial production scales, as the current asset base remains largely underutilized.
As indicated by quarterly data, working capital changes have been a significant source of cash flow volatility, with swings ranging from a $40.6 million inflow in 2025Q3 to a $22.9 million outflow in 2025Q2, reflecting the lumpy nature of milestone-driven receivables and clinical trial-related payables.
These fluctuations suggest that the company's cash position is susceptible to the timing of partner payments and the management of clinical trial logistics. Investors should remain cautious, as these working capital movements may obscure the underlying cash burn rate required to support daily operations.
Based on an analysis of the cash flow statement, the consistent add-back of stock-based compensation, which averaged over $3 million per quarter, suggests that the true economic cost of talent retention is not fully captured in the reported operating cash flow figures.
The reliance on equity-based incentives to preserve cash is a standard practice for clinical-stage firms, yet it effectively dilutes shareholders while masking the full operational cost of the business. This warrants further investigation into the long-term impact of these non-cash expenses on the company's capital structure and future dilution risks.
Quick answers to the most common questions about buying AUTL stock.
Autolus Therapeutics plc (AUTL) generated $-283.6M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Autolus Therapeutics plc (AUTL) reported negative free cash flow of $303.3M in 2025, indicating capital requirements exceeded cash from operations.
Autolus Therapeutics plc (AUTL) spent $0.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.